'Multi-target' immune therapy improves outcomes of severe lupus nephritis
A new treatment using a combination of drugs targeting different parts of the immune system improves the recovery rate for patients with severe lupus involving the kidneys, according to a report in the October Journal of the American Society of Nephrology (JASN).
"In our study, multi-target t...
What killed Naval hero John Paul Jones?
...ey failure as a result of viral or bacterial infection, which stimulated the development of a form of progressive glomerulonephritis. The interstitial nephritis
was the end result of this progressive disease. He also had pneumonia, an incidental finding not likely related to his kidney disease."
JCI table of contents: March 23, 2009
...or kallikrein proteins in anti-GBM antibodyinduced nephritis
(a mouse model of Goodpasture syndrome) and spontaneous lupus nephritis
in mice and humans.
In the study, which was led...systemic lupus erythematosus and spontaneous lupus nephritis
were found to be associated with kallikrein genes,...
Lupus is a Significant Cost to Employers, According to Thomson Reuters Study
...gher for lupus patients, though absence costs were not. Lupus
patients with nephritis
had much higher medical expenses. The mean annual
total medical expenditure...atients were almost four times higher
than those for lupus patients without nephritis
and $46,862 higher than those
of the control group.
Using similar me...
BioMarin and La Jolla Pharmaceutical Sign Worldwide (Excluding Asia Pacific) Development and Commercialization Agreement for Riquent
...ent reduces the frequency of
renal flares in lupus nephritis
patients. The ASPEN Phase 3 study is the
largest clinical study ever conducted in lupus nephritis
and there is
increasing evidence that Riquent targ...ceptionally good strategic fit for BioMarin. Lupus nephritis
is a serious
and potentially fatal orphan disease ...
Ovarian function and fertility preserved in women with severe systemic lupus erythematosus
...d by the difficult nature and impact of the disease itself."
In this retrospective evaluation of 61 postmenopausal women with SLE treated for lupus nephritis
(n=58), autoimmune hemolytic anemia (n=1) and central nervous system involvement (n=2), 39 patients received prolonged treatment with 1g/m2 intravenou...
Lupus more severe in patients with Southern European ancestry
...ilder mucocutaneous (skin) manifestations of SLE, whereas southern European ancestry contributes to more severe manifestations of the disorder such as nephritis
(inflammation of the kidneys) and increased production of specific autoantibodies (antibodies that fail to recognise and therefore attack the body's o...
Researchers investigate ways to detect lupus-associated kidney disease
...mmunology. Given that early intervention in lupus nephritis
is associated with better treatment outcome, it is...dy itself. When the antibodies attack the kidneys, nephritis
occurs, often shortening a patients life expectanc...and colleagues screened urine from mice with lupus nephritis
for the presence of four compounds VCAM-1, P-sele...
Black-white Life Expectancy Gap Reduces, Yet Remains Significant
...erinatal death, although demonstrating favorable trends, continue to keep the black-white gap unnecessarily large, and unfavorable mortality trends in nephritis
[kidney disease] and septicemia [bloodstream infection] are currently contributing to widening the gap," the authors write.
The authors emphasi...
Nephritis in Medical Technology
Nephritis in Medical Definition
Diseases of the glomerulus
| Post-infectious glomerulonephritis | Minimal...diseases of the kidney
Drug-induced interstitial nephritis
| Obstructive nephropathy | Radiation nephritis
| Reflux nephropathy | Sarcoidosis
Nephritis in Medical Dictionary
is inflammation of the kidney. The word comes from the Greek nephro- meaning "of the kidney" and -itis meaning "inflammation". Nephritis
is often caused by infections, toxins, and auto-immune diseases. More about Nephritis
: Causes and symptoms Diagnosis Tre...
is an inflammation of the kidney caused by systemic lupus erythematosus (SLE), a disease of the immune system. Apart from the kidneys, SLE can also damage the skin, joints, nervous system and virtually any organ or system in the body. Lupus nephritis
is a form of nephritis
affecting the interstitium of the kidneys surrounding the tubules. This disease can be either acute, which means it occurs suddenly or chronic, meaning it is ongoing and eventually ends in kidney failure. Interstitial nephritis
may be ...
...INTRODUCTION A percutaneous renal biopsy may be obtained for a number of reasons, ... Indications for renal biopsy in patients with lupus nephritis
... Renal biopsy . Definition. A renal biopsy is the removal of a ... Atheroembolic renal disease. Chronic glomerulonephritis. Complicat...
... Translational Research on Polyoma Virus (BK Virus) nephritis
in Renal Transplant Recipients ... Studies on Renal Transplantation - Newer Immunosuppressive ... Online Medical Dictionary and glossary with ...
... Sometimes, the kidneys aren't able to do their job properly. Other than kidney infections, the two most common kidney conditions among teens are nephritis
and nephrosis . Online Medical Dictionary and glossary with medical definitions ... Nephrosis an be caused by kidney disease, or it may be a...
...rs ... Inflammation is a natural defense of the body to protect against foreign substances or injury. ... Inflammation of kidneys is known as nephritis
and may cause ... How does inflammation relate to heart disease and stroke risk? " Inflammation " is the process by which the body respon...
Acute tubular necrosis
... Acute Tubular Necrosis . Prerenal Azotemia. Rate of creatinine rise ... Introduction· Acute Tubular Necrosis (ATN)· Tubulointerstitial nephritis
... most common causes of acute tubular necrosis (ATN) are hypotension and nephrotoxins. ... ACUTE TUBULAR NECROSIS . by Geoffrey K. ...
Acute nephritic syndrome
...hritic syndrome is the result of inflammation of the internal ... nephritic syndrome n. A syndrome comprising the clinical symptoms of nephritis
, hematuria, ... acute nephritic syndrome at Dorland's Medical Dictionary ... Acute nephritic syndrome is a group of disorders that c...
Nephritis in Biological Technology
Nephritis in Biological Definition
...t three times over the next thirty-five years.
Mendel died on January 6 , 1884 in Brno , Austria-Hungary (now Czech Republic ), from chronic nephritis
Rediscovery of Mendel's work
It was not until the early 20th century that the importance of his ideas was realized. In 1900 , his work w...
Renal cell carcinoma
Renal failure (acute and chronic)
Dialysis and kidney transplants
Generally, one can live fine with just one kidney. If both kidneys do not function properly, dialysis is pe...
Nephritis in Biological Dictionary
...ften used alone to designate one of the glomeruli of the kidney. ... glomerulus ... glomeruli . cyclooxygenase-2 (COX-2) glomerular. glomeruli . nephritis
... glomerulus synonyms. glomerulus usage examples and glomerulus quotes. ... glomeruli -·li′ (-lī′) any cluster or structure of blood ves...