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Nematode in Medical News

New devices to boost nematode research on neurons and drugs

A pair of new thin, transparent devices, constructed with soft lithography, should boost research in which nematodes are studied to explore brain-behavior connections and to screen new pharmaceuticals for potential treatment of parasitic infections in humans, report 10 scientists at three institut...

Researchers gain ground in efforts to fight parasite infection

...r author of the new study in PNAS, had made the discovery in C elegans, a nematode about the size of a pinhead. In the new study, the UT Southwestern resea...d source the host is available," Dr. Mangelsdorf said. Many infectious nematode larva live in the soil, often in areas where proper sanitation is lacking. ...

Key protein may explain the anti-aging and anti-cancer benefits of dietary restriction

... targets for both designing and testing drugs which could mimic the effects of dietary restriction in humans," said Kapahi. The research involved nematode worms that were genetically altered to both under and over-express HIF-1. The animals, which are the most-often used model to study aging, were fed di...

Worms Reveal More of Longevity's Secrets

...tt Kaeberlein, an assistant professor of pathology at the University of Washington, Seattle, said in a university news release. His team found that nematode worms live longer if they're also able to switch on the hypoxic response when oxygen levels are normal. In addition, the worms' cells contain fewer to...

Researchers ID Suite of Genes in Aging Process

...use these biomarkers to test anti-aging drugs. The study, which included nematode worms, microarrays that measure changes in gene expression, and complex com...0s, while other 70-year-olds seem prematurely aged. The same is true of the nematode worms used in the study. The Buck Institute team conducted individual wh...

New research on mutation in yeast can enhance understanding of human diseases

...d a fundamental question: "What is the baseline rate and spectrum of mutation in yeast?" They found that, like the previously studied mutations in the nematode Caenorhabditis elegans, the yeast Saccharomyces cerevisiae had a very high rate of mutation from generation to generation. Its patterns of mutatio...

Nuvelo Announces Presentations on NU206 and rNAPc2 at 2008 American Association for Cancer Research Annual Meeting

...tion and therapeutic potential of NU206 (R-spondin1) for chemotherapy or radiation-induced oral mucositis, and preclinical data evaluating recombinant nematode anticoagulant protein c2 (rNAPc2) in mouse models of colorectal cancer, will be presented at the 2008 American Association for Cancer Research (AACR) ...

The onchocerciasis parasite showing signs of resistance

...nfection caused by Onchocerca volvulus, a parasite nematode worm transmitted to humans by a species of black f...s as a marker of resistance to ivermectin in other nematode species parasitic on cattle. As a control, they mo.... These results could be the sign of adaptation of nematode worm populations to repeated treatments using this...

Could Hydrogen Sulfide Hold the Key to A Long Life?

... used to put mice into a state of reversible metabolic hibernation -- has now been shown to significantly increase life span and heat tolerance in the nematode worm, or C. elegans. These findings by Mark Roth, Ph.D., a member of the Center's Basic Sciences Division, and Dana Miller, Ph.D., a postdoctoral re...

A longer-living, healthier mouse that could hold clues to human aging

...esearch on Ageing, led by Professor Linda Partridge. The teams at the Centre analyse the cellular and biochemical mechanisms of ageing in fruit flies, nematode worms and mice, and in particular the role of insulin signalling. Their work was recognised in June 2007 by a Strategic Award from the Wellcome Trust ...
Nematode in Medical Technology

Nuvelo Announces Presentation on rNAPc2 at American College of Cardiology 56th Annual Scientific Session

.... today announced that clinical data from the ANTHEM (Anticoagulation with rNAPc2 To Help Eliminate MACE)/TIMI 32 Phase 2 trial looking at recombinant nematode anticoagulant protein c2 (rNAPc2) in patients with non-ST-elevation acute coronary syndromes (NSTE-ACS) will be presented in a V-poster presentation a...

Nuvelo Announces Presentations on rNAPc2 and NU172 at the XXIst Congress of the International Society on Thrombosis and Haemostasis

...daq: NUVO) today announced that data from the ANTHEM (Anticoagulation with rNAPc2 To Help Eliminate MACE)/TIMI 32 Phase 2 trial looking at recombinant nematode anticoagulant protein c2 (rNAPc2) in patients with acute coronary syndromes (ACS), preclinical data evaluating rNAPc2 in mouse models of colorectal ca...
Nematode in Medical Dictionary

Nematode

The "roundworms" or "nematodes" are the most diverse phylum of pseudocoelomates, and one of the most diverse of all animals. Nematode species are very difficult to distinguish; over 80,000 have been described, of which over... Allows access to their expressed sequence tags...

Toxocariasis

...ntroduction, prevalence, prognosis, profile, symptoms, diagnosis, misdiagnosis, and treatment toxocariasis n. A disease caused by a parasitic nematode of the genus Toxocara , transmitted to humans by ingestion of a substance, such as soil, toxocariasis . toxoplasmosis. trichinosis. visceral lar...

Roundworms

... The " roundworms " or "nematodes" are the most diverse phylum of pseudocoelomates, and one of the most diverse of all animals. nematode species are very difficult to distinguish; over 80,000 have been described, of which over... Roundworm infection can have numerous negative ef...

Pinworm

...ommon intestinal worm infection, which can survive up to two weeks on clothing, bedding, and other objects. pinworm ( ) n. Any of various small nematode worms of the family Oxyuridae that are parasitic on ... pinworm . Dictionary: pin·worm (pĭn'wûrm') Home > Library > ... ... of Pinwor...

Hookworm Infection

... The hookworm is a parasitic nematode worm that lives in the small intestine of its host, which may be a mamma... microscopic images. hookworm ( ) n. Any of numerous small parasitic nematode worms of the family ... Hookworm infection is widely distributed thr...

Hookworm

... The hookworm is a parasitic nematode worm that lives in the small intestine of its host, which may be a mamma...enale and Necator... hookworm ( ) n. Any of numerous small parasitic nematode worms of the family Ancylostomatidae, having a ... hookworm . Dictionar...
Nematode in Biological News

ISU researchers help map first plant-parasitic nematode genome sequence

AMES, Iowa -- There are numerous plant-parasitic nematodes in the world, but only a handful are responsible for the largest part of an estimated $157 billion in agricultural damage globally every year. Nematodes are small worms that burrow into plant roots and feed off living cells. Now, Iowa S...

Soybean varieties viable in southern Indiana, resistant to root-knot nematode

WEST LAFAYETTE, Ind. - Purdue University researchers have identified several soybean varieties that grow well in areas of the Midwest like southern Indiana and are resistant to root-knot nematodes, a plant-destroying parasite with a recently confirmed presence in that part of the state. The res...

UGA scientists engineer root-knot nematode resistance

University of Georgia professor Richard Hussey has spent 20 years studying a worm-shaped parasite too small to see without a microscope. His discovery is vastly bigger. Hussey and his research team have found a way to halt the damage caused by one of the world's most destructive groups of plant pat...

Program finds lost genes in nematode genome

A computer scientist at Washington University in St. Louis has applied software that he has developed to the genome of a worm and has found 150 genes that were missed by previous genome analysis methods. Moreover, using the software, he and his colleagues have developed predictions for the existenc...

Pinhead-size worms + robot = new antibiotics

... (a type of worm) infected with E. faecalis (a type of bacteria). That bacterium causes life-threatening infections in humans. C. elegans are tiny nematode worms that are widely used in scientific research. The tests identified 28 potential new drugs never before reported to have germ-fighting effects. So...

Restoring a natural root signal helps to fight a major corn pest

... roots. The substance attracts nematodes that attack and kill larvae of the Western corn rootworm, a voracious root pest. In field tests, the enhanced nematode attraction resulted in reduced root damage and considerably fewer surviving rootworms. Further fine-tuning of this natural defense strategy will allow...

Nematode courting caught on camera

... Researchers studying the nervous control of nematode mating behavior have produced video footage of a male worm preparing to mate with a hermaphrodite. Writing in the open access journal BMC Biology , A...

Computers aid in cracking deception in plants

...n, the soybean cyst nematode. The soybean cyst nematode is a small parasitic roundworm that infects the ro... soybean plant. As part of its modus operandi, the nematode secretes proteins into the soybean that change the...ses it to create a specialized cell from which the nematode feeds. Scientists think molecular mimicry may be i...

SIRT1 takes down tumors

...tudy will be published online April 13 ( www.jcb.org ) and will appear in the April 20 print issue of the Journal of Cell Biology . The yeast and nematode equivalents of SIRT1 are fountains of youth that stretch lifespan. Whether SIRT1 slows aging in mammals isn't certain, but it's beneficial in other wa...

Parasite-resistant peppers green alternatives to chemical pesticides

...at nematode-resistant varieties such as Charleston Belle and Carolina Wonder are viable alternatives to methyl bromide for managing southern root-knot nematode in bell pepper in sub-tropical environments. To increase the availability of parasite-resistant vegetables, commercial seed companies are currently de...
Nematode in Biological Technology

Syngenta and Evogene to Collaborate on Soybean Nematode Resistance

RESEARCH TRIANGLE PARK, N.C., June 26 /PRNewswire/ -- Syngenta Biotechnology, Inc. announced today that it has entered into a collaboration agreement with Evogene, Ltd., focusing on identifying plant genes related to soybean nematode resistance. Under the agreement, Syngenta will receive exclusive...

Pasteuria Bioscience Receives EPA Registration for Nematode Control

ALACHUA, Fla., June 8 /PRNewswire/ -- Pasteuria Bioscience announced that it has received registration from the United States Environmental Protection Agency (EPA) for Pasteuria usgae . This is a critical step towards the commercial use of Pasteuria spp., a natural bacteria prevalent in soi...

Divergence Receives $1.2 Million in Grants, Including NSF Grant to Fund Continuing Nematode Research in Corn

Company's work could help farmers protect against billions in pest losses annually St. Louis, MO (PRWEB) April 29, 2009 -- In the past year, St. Louis biotech firm Divergence, Inc. , has received more than $1.2 million in research grants, including a $500,000 grant jus...

Dow AgroSciences, NemGenix Establish New Collaboration in Plant Biotechnology

...search team is excited to have the opportunity to build on our expertise in nematode control with the strength and capabilities of a partner such as Dow AgroSci...partment of Education, Science and Training to undertake the development of nematode resistant wheat. See www.nemgenix.com . About Dow AgroScience...

Divergence Raises $11.8 Million in Series C Financing

...financing will be used to advance Divergence's nematicide program. The company is developing molecules for the control of plant parasitic nematodes. nematode control is the largest unsolved pest problem in agriculture limiting the yield of crops worldwide and causing billions of dollars in crop damage annua...

Combating infection of crops by nematodes is soon to improve

... cells and to start producing food for the nematode. This plant cell − which can become as large as 200 normal plant cells − is called the nematode feeding site. Nematodes trick the plant Research has revealed that nematodes mislead the plant by disrupting its hormonal regulation. The plant ...

DuPont and Athenix Collaborate to Advance Insect Control in Corn, Soybeans

...lants, microbes, genes, enzymes, and processes with emphasis on two major markets: 1) novel agricultural traits for growers such as insect resistance, nematode resistance, herbicide tolerance, and their use for the crop production industry; and 2) the discovery of genes and proteins for use in the sustainable...

Growing old together: Yeast, worms and people may age by similar mechanisms

...cted a genome-wide analysis of the yeast Saccharomyces cerevisiae and the nematode worm Caenorhabditis elegans , to identify genes that may regulate aging in...mon functional pathways. We find that there is significant overlap between nematode and yeast aging genes, particularly those in nutrient-response pathways, de...

Montana State University lab gives early warnings about biological invaders

...tified in areas neighboring Montana (the pale cyst nematode in Idaho and the golden cyst nematode in Alberta) but not yet in Montana. "Say the ne...ot out that Montana had either golden or pale cyst nematode in potatoes," Burrows says. "If that got into the ...

Mechanism for the in-vivo transport of siRNA

...o established the technique of RNA interference, in which double-stranded RNA switches genes off efficiently and specifically. The scientists used the nematode (roundworm) Caenorhabditis elegans to study this. Subsequently, however, considerable problems arose in the attempt to transfer the strategy used by M...
Nematode in Biological Products

Soil Nematode microRNA Microarray from LC Sciences

Description: Microarrays designed for genome-wide microRNA expression profiling and built on the flexible and powerful Paraflo microfluidic on-chip synthesis platform. These microarrays are available as part of our comprehensive microRNA Expression Profiling Service. Probe Content The Soil Nematode microRNA ...
Company:LC Sciences
Nematode in Biological Definition

Apoptosis

... of Molecular Biology (LMB) in Cambridge, UK. It was at this lab that during the 1970s and 80s, a team led by John Sulston succeeded in tracing the nematode C. elegan's entire embryonic cell lineage. In other words, Sulston and his team had traced where each and every cell in the roundworm's embryo ca...

Genome project

...or corn) Escherichia coli bacterium E.coli SARS virus Arbacia punctulata the purple-spined sea urchin Caenorhabditis elegans a nematode worm Brachydanio rerio Zebrafish Xenopus laevis The African clawed toad Oryzias latipes A medakafish Takifugu rubipres A ...

Insulin

... Insulin as a medication Principles Insulin is absolutely required for all animal (including human) life. The mechanism is almost identical in nematode worms (ie, C. elegans ), fish, and in mammals. In humans, insulin deprivation due to the removal or destruction of the pancreas leads to death in d...

Neuron

...ment, byproduct of synthesis of catecholamines) and lipofuscin (yellowish-brown pigment that accumulates with age). Neurons of the brain The nematode worm ( Caenorhabditis elegans ) has 302 neurons. Scientists have mapped all of the nematode's neurons. The human brain has about 100 billion ( 10...
Nematode in Biological Dictionary

Post-meiotic segregation

...biological,biology dictionary,biology terminology,biology terms,biology abbreviations ... Post - meiotic segregation ... Slide 26 of 27 ... nematode protein-coding gene pms-2. Represented by 28 ESTs from 5 cDNA libraries. ... PMS ( Post Meiotic Segregation ) family member (pms-2) (pms-2) (p...

Phage

...of antibacterial treatment that harnesses the bacteria ... These concentrated, polyvalent phage preparations are typically comprised of ... The nematode acts as a vector for the phage , facilitating the spread of its own competitor. ... We employed the segmented RNA phage 6 and Pseudomonas syringa...

Parthenogenesis

...it is ... Parthenogenesis summary with 18 pages of encyclopedia entries, essays, summaries, research ... Meiotic Parthenogenesis in a Root-Knot nematode Results in ... Jacques Loeb\'s research on fertilization was part of a larger agenda that he ... Artificial parthenogenesis brought Loeb scient...

Microtubules

... is concerned with the progression from molecules to multicellular organisms. ... The microtubules in six specialized touch-sensitive neurons in the nematode ... With respect to microtubules , what is dynamic instability and why is it important to the cell? ... How might microtubules organize differen...

Maternal effect

...al Fasting During Pregnancy. Douglas Almond. and ... fasted: "the effect on maternal glucose levels during Ramadan fasting is cumulative. ... nematode protein-coding gene mes-4. Represented by 10 ESTs ... Caenorhabditis elegans Maternal Effect Sterile family member (mes-4) (mes-4) mRNA, compl...

Endosymbiont

... Jun 06, 2008 - Where do you get your genes? ... endosymbiont that somehow transfers bits of its genome into yours (which is a ... Soybean cyst nematode (SCN) is an important yield limiting pest of soybean in ... Candidatus paenicardinium endoi', an endosymbiont of the plant-parasitic ... PLoS ONE...

Ascaris

... Ascaris is a genus of parasitic nematode worms known as the giant intestinal roundworms. On... lumbricoides is a helminth or more specifically a nematode (roundworm) ... Feces from a human infected with...ean? ... Ascaris /As·ca·ris/ (-ris) a genus of nematode parasites of the large intestine. ... Ascari...
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