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Necrotizing in Medical News

Sigma-Tau Pharmaceuticals and Danisco BioActives Announce Partnership Agreement to Develop Drug Candidate for Prevention of Necrotizing Enterocolitis

GAITHERSBURG, Md., April 7 /PRNewswire/ -- Sigma-Tau Pharmaceuticals, Inc. and Danisco BioActives announced today that they have signed a partnering agreement for the development of a new biologic drug candidate, which may help to prevent a deadly disease called necrotizing enterocolitis (NEC). ...

Blood tests can help detect presence of necrotizing soft tissue infections

TORRANCE (Dec. 4, 2008) With less than half of patients with necrotizing soft tissue infections displaying the physical signs of these very serious infections, researchers have found two simple blood tests can help physicians diagnose what is commonly known as "flesh-eating bacteria," according t...

A potential anti-ulcer herb medicine: Rocket 'Eruca sativa'

...ced the basal gastric acid secretion, titratable acidity and ruminal ulceration. Rocket extract significantly attenuated gastric ulceration induced by necrotizing agents (80% ethanol, 0.2 mol/L NaOH, 25% NaCl), indomethacin and hypothermic restraint stress. The anti-ulcer effect was further confirmed histologica...

25 Clinical Abstracts at National Conference Spotlight Clinical Utility of Somanetics INVOS System in Neonates

...e to severe conditions that are traditionally difficult to diagnose such as necrotizing enterocolitis and patent ductus arteriosis as well as to the need for blood...ndition escalates and causes damage." One disease elusive to detect is necrotizing enterocolitis (NEC), a dying off of the intestinal and bowel tissue that of...

ULURU Inc. Announces Altrazeal(TM) Clinical Experience Published in the International Wound Journal

...Nanoflex(TM) powder dressing for wound management following debridement for necrotizing fasciitis in the diabetic foot." The article details the treatment of a di...Nanoflex(TM) powder dressing for wound management following debridement for necrotizing fasciitis in the diabetic foot" International Wound Journal , 6(2): 133-13...

Packard/Stanford study suggests two causes for bowel disease in infants

... children and young adults. The bowel disorder, necrotizing enterocolitis, or NEC, is seen mainly among premat...y curing the disease." To gain insight into how necrotizing enterocolitis starts, Dutta and his collaborators ...ts who had a congenital heart defect together with necrotizing enterocolitis and 126 infants who had...

Arterial infusion using gabexate mesilate: Is it effective therapy for severe acute pancreatitis?

...cute pancreatitis in Japan, but the protease inhibitors used to treat acute necrotizing pancreatitis cannot easily reach the pancreas when administered intravenous...ibly reduce the mortality rate and incidence of infectious complications in necrotizing pancreatitis. Furthermore, until now, most cases have been used with nafamo...

Amylin Pharmaceuticals Diabetes Drug Byetta the Focus of California Lawsuit

...sp;  Deleon's lawsuit comes two days after the Food and Drug Administration (FDA) announced that it has received six reports of hemorrhagic or necrotizing pancreatitis in patients taking Byetta® since October of 2007. Two of the six patients died. In a press release, the FDA said it is "workin...

Actress Continues Fight Against Hospital Errors & Rise in MRSA Cases

... to becoming a real-life patient after contracting necrotizing Fasciitis (NF), 'Man-eating Flesh Disease'. This l...d that would lead to the traumatizing diagnosis of necrotizing Fasciitis. To view the ravaging effects of this di... to Cole's site at http://www.aliciacole.com . necrotizing Fasciitis (NF) is a bacterial infection that attac...

Aurora St. Luke's Medical Center Installs the Country's Second-Largest Hyperbaric Chamber

...because of chronic medical conditions such as diabetes and poor circulation. It is also used to treat other difficult to heal wounds such as necrotizing infections (flesh-eating bacteria), radiation tissue damage, burns, carbon monoxide poisoning, smoke inhalation and scuba diving injuries. ...
Necrotizing in Medical Technology

ULURU Inc. to Present Altrazeal(TM) Clinical Evidence and Advanced Therapeutic Research at the Diabetic Foot Global Conference (DFCon) 2009

...gement of Soft Tissue Wounds ". This research details the application of Altrazeal(TM) in the treatment of a patient following radical debridement of necrotizing fasciitis. Commenting on the work, DFCon organizer and one of the study's co-authors, Dr. David Armstrong, Professor of Surgery and Director, Souther...

NPS Reports Successful GATTEX(TM) Extension Study

...thelium. NPS is also pursuing development of GATTEX as a possible treatment for chemotherapy-induced gastrointestinal mucositis in cancer patients and necrotizing enterocolitis in preterm infants. About NPS Pharmaceuticals NPS Pharmaceuticals is developing specialty therapeutics for gastrointestinal and endo...

Cytokine Announces Oral Efficacy of Anti-Cytokine Semapimod

...mod's efficacy in animal models of inflammatory and proliferative diseases, including endotoxic shock and toxicity, pancreatitis, ischemia and stroke, necrotizing enterocolitis, and neointimal formation. Despite early signals of efficacy, the Phase II studies CPSI conducted in Crohn's disease were dose-limited b...

Clinical Benefits Demonstrated with Low-Dose GATTEX(TM) in Phase 3 Short Bowel Syndrome Study

...ions with high unmet needs, including chemotherapy-induced GI mucositis and necrotizing enterocolitis." There are several hypotheses that may explain the higher r... for chemotherapy-induced gastrointestinal mucositis in cancer patients and necrotizing enterocolitis in preterm infants. Conference Call Information A conferenc...
Necrotizing in Medical Products

ImmuGlo COMVI-ANCA (ethanol+formalin fixed)

Description:...t for the detection and semi-quantitation of anti-neutrophil cytoplasmic antibodies (ANCA) in human serum. ANCA are found in the sera of patients with necrotizing vasculitides and hence, serve as an aid to the clinical and other laboratory findings in the diagnosis of these disorders....
Company:IMMCO Diagnostics

Anti-MPO ANCA EIA Auto-Immune Markers 013-MPO-48 Myeloperoxidase

Description:...CA are a family of autoantibodies associated with vasculitic disorders and glomerulonephritis (GN). They were first described in 1982 in patients with necrotizing GN (1) and in patients with vasculitis and GN in 1984 (2). In 1985 research on Wegeners granulomatosis (WG), independent from the earlier observations...
Company:ALPCO Diagnostics
Necrotizing in Medical Definition

Pathology

... Salivary glands Drooling - Benign lymphoepithelial lesion - Frey's syndrome - Mikulicz's disease - Mucus retention cyst - Mumps - necrotizing sialometaplasia - Ranula - Sialadenitis - Sialolithiasis - Sjogren's syndrome - Stomatitis - Xerostomia Tongue Geographic tong...
Necrotizing in Medical Dictionary

Imperforate anus

...om birth) defect in which the opening ... Imperforate anus may occur in several forms. ... Imperforate Anus . Inguinal Hernia. Laparoscopy. necrotizing Enterocolitis ... Imperforate anus is a relatively common congenital malformation that occurs in ... Imperforate anus repair is surgery...

Vasculitis

...al Arteritis " ... Are there additional vasculitis disorders that can cause neurological symptoms? ... There are many types of vasculitis . ... necrotizing vasculitis is an inflammatory condition of blood vessels ... Allergic vasculitis ... ...

Toxic Shock Syndrome

...re, often life-threatening illness that develops suddenly after an infection. About invasive group A streptococcal infections with or without necrotizing fasciitis associated with shock and organ failure. Detailed information on toxic shock syndrome , including symptoms, diagnosis, treatme...

Streptococcal infections

...ions , including strep throat, scarlet fever and necrotizing fasciitis. Streptococcal Infections glossa... or impetigo, to severe and even life-threatening necrotizing fasciitis and streptococcal toxic shock syn... ... Serious streptococcal infections (such as necrotizing fasciitis, endocarditis, ... ... Respiratory D...

Streptococcal Infection

...ions , including strep throat, scarlet fever and necrotizing fasciitis. Then, every streptococcal infect... ... Serious streptococcal infections (such as necrotizing ... Streptococcal infections are caused by... or impetigo, to severe and even life-threatening necrotizing fasciitis and streptococcal toxic shock syn...

Scleritis

... systemic autoimmune ... Scleritis ... Scleritis may be the initial or only presenting clinical manifestation of these ... In severe cases of necrotizing scleritis , the sclera may become transparent due ... Treated improperly, scleritis can render a great deal of damage to the ... Scleritis ...

Pulmonary aspergillosis

...ve aspergillosis and pulmonary aspergilloma. Allergic bronchopulmonary aspergillosis information including symptoms, diagnosis, ... Chronic necrotizing pulmonary aspergillosis . more related diseases... Pulmonary aspergillosis - invasive - Overview, Invasive pulmonary aspergillosis is...

Porphyrias

...e types, causes, symptoms, diagnosis, and ... Nail-Patella Syndrome, Narcolepsy, Narcotic Drugs, Nasal Trauma, Nausea and Vomiting, Near-Drowning, necrotizing Enterocolitis, Neonatal Jaundice, Neonatal ... Porphyria's Lover summary and study guide with notes, essays, quotes, analysis and pictures ... P...

Pancreatic abscess

...ularly if you have recently had a ... A pancreatic abscess (PA) is a collection of... Pancreatic abscess is a late complication of acute necrotizing pancreatitis (ANP) ... Pancreatic abscess is a cavity of pus within the pancreas. ... < http://healthguide.howstuffwor ks.com/ pancre...

Otitis

...ormation handout on otitis externa, written by the author of this ... necrotizing (malignant) external otitis , an infection involving the temporal and ... Patients with necrotizing external otitis complain of severe otalgia that ... Provides informat...
Necrotizing in Biological News

NIH expands Human Microbiome Project; funds sequencing centers and disease projects

...D., Washington University School of Medicine, Saint Louis Digestive tract: necrotizing Enterocolitis $1 million This group of researchers will examine the potential connection between the intestinal microbiome and the development of necrotizing enterocolitis, a gastrointestinal disorder that can damage the intestine, i...

Repeat C-section before 39 weeks raises risk of neonatal illness

...as diagnosed with a number of conditions, including respiratory distress syndrome and/or transient tachypnea of the newborn, newborn sepsis, seizures, necrotizing entercolitis, hypoxic ischemic encephalopathy, required ventilator support within 24 hours of birth, had umbilical cord arterial pH (a measure of oxyg...

Genetic mutation causes familial susceptibility for degenerative brain disease

...teins migrate in and out of the cell's genetic command center the nucleus puts some families at higher risk for the degenerative brain disease acute necrotizing encephalopathy (ANE). This is the conclusion of a global study to be published Jan. 9 by the American Journal of Human Genetics , and currently po...

American Chemical Society's Weekly PressPac -- Sept. 24, 2008

...s of human breast milk. Researchers have found, for example, that certain sugars in breast milk could be developed into treatments that help fight necrotizing enterocolitis (NEC), a potentially deadly disease that affects about 10 percent of premature infants. Some types of sugars in breast milk appear to pr...

Leading cause of death in 'preemies' might be controlled by resetting a molecular switch

...eceptor that normally switches on the intestines immune response but instead becomes too intense in the presence of stress and toxins may help reverse necrotizing enterocolitis (NEC), a leading cause of death in premature newborns, according to scientists at the American Society for Cell Biology 47th annual meet...

Solved: The mystery of flesh-eating bacteria's relentless attack

...Journal, could lead to new strategies for treating necrotizing fasciitis and halting its rapid destruction of tis...struction on muscle and skin tissue in the form of necrotizing fasciitis, which kills roughly 30 percent of its v...l interventions, the known treatments, often fail. necrotizing fasciitis is a serious but rare infection of the s...

Study indicates dramatic rise in antibiotic-resistant community-acquired staph infections

...ses, and typically infects tissues through cuts or rashes. Those infections can remain minor, or lead to illnesses ranging from boils or abscesses to necrotizing skin infections, pneumonia and sometimes blood stream infections. The Centers for Disease Control and Prevention (CDC) reports that staph is one of t...

Flesh-eating bacteria escape body's safety net

...om simple throat and skin infections to life-threatening conditions such as necrotizing fasciitis ("flesh-eating disease") and toxic shock syndrome. "These find...nic Strep strain that was originally isolated from a patient suffering from necrotizing fasciitis. "Deprived of this single enzyme, the mutant Strep strain was ...

Emerging staph strains found to be increasingly deadly and deceptive

...eat, affecting vital organs and leading to toxins poisoning the blood and infection overwhelming the heart. One of the most severe types of disease is necrotizing pneumonia, where bacteria destroy lung tissue. "The reason that some mild infections become severe or fatal is not well understood, but virulence i...
Necrotizing in Biological Technology

Trillium Strengthens its Board of Directors

...he company's lead program, a recombinant heparin-binding epidermal growth factor-like growth factor (HB-EGF), is being developed for the prevention of necrotizing enterocolitis and the treatment of interstitial cystitis. IND filing on the lead product, TTI-1612, was submitted to the FDA in October 2008. In addit...

Trillium secures additional financing on the strength of lead program and proprietary position around the CD200 immunoregulatory pathway

... recombinant growth factor under parallel development for the prevention of necrotizing enterocolitis and the treatment of interstitial cystitis. TTI-1612 is on tr...gram, a recombinant growth factor, is being developed for the prevention of necrotizing enterocolitis and the treatment of interstitial cystitis. Trillium has two ...

NPS Pharmaceuticals Reports Third Quarter 2007 Financial Results, Revises Financial Guidance

...e U.S. sales of between $150 and $250 million in this indication. NPS is also running pre-clinical studies of GATTEX in support of a pediatric IND in necrotizing enterocolitis. NEC affects 12,000 neonates annually in the U.S. and mortality approaches 50% in infants weighing less than fifteen-hundred grams. Addi...
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