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Narcolepsy in Medical News

Researcher IDs Narcolepsy as Autoimmune Disease

Discovery of 2 gene variants that kill off protective hormone could lead to new treatments MONDAY, May 4 (HealthDay News) -- Stanford University researchers say they have determined that the sleep disorder narcolepsy is actually an autoimmune disease. The finding, published in the ...

Cephalon Announces the Availability of NUVIGIL for the Treatment of Excessive Sleepiness Associated with Treated Obstructive Sleep Apnea, Shift Work Disorder and Narcolepsy

NUVIGIL Launch Enhanced by Robust Patient Access Programs FRAZER, Pa., June 1 /PRNewswire-FirstCall/ -- Cephalon, Inc. (Nasdaq: CEPH ) today announced that NUVIGIL(R) (armodafinil) Tablets [C-IV], a longer-lasting formulation of modafinil, is now available. NUVIGIL is indicated to improve ...

Publication Provides a Wake-Up Call For Clinicians Treating Narcolepsy

MONTVALE, N.J., April 9 /PRNewswire/ -- Narcolepsy remains underdiagnosed and undertreated even though this neurologic dysfunction is better understood and the available treatment options have increased in the last decade. To help health care providers and psychiatrists treat this neurologic...

Lower metabolism, eating behavior possibly explain the cause of overweight in narcolepsy

WESTCHESTER, Ill. A lower metabolism, as well as slight changes in eating behavior, could explain the positive energy balance leading to being overweight in narcolepsy, according to a study published in the October 1 issue of the journal SLEEP. The study, authored by Dorothe Chabas, MD, PhD, o...

UCLA Researchers Discover Link Between Parkinsons and Narcolepsy

Parkinson's disease is well-known for its progression of motor disorders: stiffness, slowness, tremors, difficulties walking and talking. Less well known is that Parkinson's shares other symptoms with narcolepsy, a sleep disorder characterized by sudden and uncontrollable episodes of deep sleep, s...

Addrenex Pharmaceuticals Announces Licensing Agreement With Dream Pharma

... ADHD) and ADX-415 (hypertension and menopausal flushing), Addrenex has two proprietary products in clinical development, ADX-N05 for the treatment of narcolepsy and ADX-117 for procedural sedation. For more information, visit www.addrenex.com ...

Jazz Pharmaceuticals to Present Data From First Phase III Study of Sodium Oxybate in Patients With Fibromyalgia

...lso approved by the European Medical Evaluation Agency for the treatment of narcolepsy with cataplexy in adult patients. Most commonly reported adverse drug reactions in narcolepsy patients are dizziness, nausea and headaches. Sodium oxybate has the potent...

Narcolepsy is an autoimmune disorder, Stanford researcher says

...rder confirming experts' long-held suspicion that narcolepsy is an autoimmune disease. The work, which will ...bringing this story to a close and that we can use narcolepsy as a model for other diseases." narcolepsy affects about one in 2,000 people and is character...

Treating sleep disorders in people with traumatic brain injury may not eliminate symptoms

...jects (35) were free of a sleep disorder, while 23 percent (13) had OSA, 7 percent (4) had periodic limb movements in sleep (PLMS), 5 percent (3) had narcolepsy without cataplexy and 3 percent (2) had post-traumatic hypersomnia. Participants underwent objective evaluation by overnight polysomnography to dete...

Narcolepsy Drug Might Be Addictive

...ding comes as use of stimulant for enhanced mental function is on the increase TUESDAY, March 17 (HealthDay News) -- A drug used to treat narcolepsy is increasingly being taken to sharpen mental skills, but researchers now report troubling evidence that it also harbors the potential for abuse. M...
Narcolepsy in Medical Technology

Addrenex Pharmaceuticals Expands Product Pipeline by Licensing New Drug to Treat Narcolepsy

DURHAM, N.C., May 13 /PRNewswire/ -- Addrenex Pharmaceuticals today expanded its pipeline of products aimed at adrenergic regulation with the signing of an agreement to license a new drug for the treatment of narcolepsy, a chronic and debilitating sleep disorder, as well as other neurologic and ps...

Jazz Pharmaceuticals and UCB Announce Second Phase III Study of Sodium Oxybate in Patients With Fibromyalgia Meets Primary Endpoints

...ution) in Europe , where it is approved by the EMEA for the treatment of narcolepsy with cataplexy in adult patients under a license from Jazz Pharmaceuticals. Most commonly reported adverse drug reactions in narcolepsy patients are dizziness, nausea and headaches. Sodium oxybate has the potent...

Data Suggest Sodium Oxybate Significantly Improves Pain and the Core Symptoms of Fibromyalgia

...roved by the European Medical Evaluation Agency (EMEA) for the treatment of narcolepsy with cataplexy in adult patients. Most commonly reported adverse drug reactions in narcolepsy patients are dizziness, nausea and headaches. Sodium oxybate has the potent...

Jazz Pharmaceuticals, Inc. Completes Enrollment in Second of Two Phase III Clinical Trials of Sodium Oxybate to Treat Fibromyalgia

...the U.S. Food and Drug Administration-approved indications. It is also approved by the European Medical Evaluation Agency (EMEA) for the treatment of narcolepsy with cataplexy in adult patients. Most commonly reported adverse drug reactions in narcolepsy patients are dizziness, nausea and headaches. Sodium o...

Jazz Pharmaceuticals and UCB Announce Positive Phase III Results for Sodium Oxybate (JZP-6) in Fibromyalgia

... the U.S. Food and Drug Administration-approved indications. It is also approved by the European Medical Evaluation Agency (EMEA) for the treatment of narcolepsy with cataplexy in adult patients. Most commonly reported adverse drug reactions in narcolepsy patients are dizziness, nausea and headaches. Sodium oxy...
Narcolepsy in Medical Dictionary

Narcolepsy

Narcolepsy is chronic sleep disorder, or dyssomnia. The condition is characterized by excessive daytime sleepiness (EDS) in which a person experiences extreme fatigue and possibly falls asleep at inappropriate times, such as whilst at work or at school. A narcoleptic... Narcolepsy is ...

Sleeping problems

... Learn about a variety of sleep problems including circadian rhythm disorder, insomnia, snoring, sleep apnea, narcolepsy and others. Learn about different sleep problems and the symptoms associated with these disorders. ... Help for Infant Sleep Problems . Ti...

Drowsiness

...y, your doctor may prescribe stimulants (such ... Drowsiness Christina Care Health System Wilmington, Delaware DE ... For drowsiness due to narcolepsy , stimulants (like Ritalin) may be prescribed. ... ...

Diagnosis

...& Treatment for Medical Providers. Comprehensive resources to prevent, diagnose , and manage child/adolescent abuse victims Diagnosis of narcolepsy is based on the clinical recognition of excessive ... Original Source: http://www.sleepdisorderchanne l.com/narcolepsy/ diagnosis .shtml ... Di...

Amphetamine

...atigue and decreased appetite. Drugs with similar psychoactive properties can be referred to... Amphetamine is a stimulant and is used to trat narcolepsy and attention deficit disorder. ... Amphetamine passes into breast milk and may affect a nursing baby. ... Learn about the prescriptio...
Narcolepsy in Biological News

Genetic study confirms the immune system's role in narcolepsy

Scientists funded by the National Institutes of Health have identified a gene associated with narcolepsy, a disorder that causes disabling daytime sleepiness, sleep attacks, irresistible bouts of sleep that can strike at any time, and disturbed sleep at night. The gene has a known role in the immu...

What happens when we sleep

...leep-wake cycle and vital insight into the basis of sleep disorders such as narcolepsy and possibly also other diseases such as depression and Parkinson's. Sl...d turn off during sleep and in their absence, animals and humans experience narcolepsy with cataplexy or sudden loss of mucle tone. However, the role of MCH neuro...

Natural brain substance blocks weight gain in mice, UT Southwestern researchers discover

...nd sleep. He found that reduced levels of orexin lead to the sleep disorder narcolepsy in both rodents and humans. Orexin can boost the appetite in the short t...that mimics the action of orexin on its receptor, we might be able to treat narcolepsy and other sleep disorders, as well as obesity," Dr. Yanagisawa said. "We ha...

New mechanism explains glucose effect on wakefulness

...food seeking, hormone release, and metabolic rate, to ensure that the brain always has adequate glucose." Malfunction of orexin neurons can lead to narcolepsy and obesity, and researchers have also found evidence that orexin neurons play a role in learning, reward-seeking, and addiction, wrote the researcher...
Narcolepsy in Biological Technology

$425 Million Cephalon Civil Settlement and Criminal Fine; In America's Largest

...uted federal regulations on a grand scale for years by off-label marketing its first three prescription drugs far beyond the cancer pain, epilepsy and narcolepsy specialists for whose patients those drugs had been FDA-approved. Instead, Cephalon focused its national marketing muscle on unapproved uses, targetin...

FDA Grants Orphan Drug Designation to TREANDA, an Investigational Treatment for Chronic Lymphocytic Leukemia

...medications for orphan diseases. The company's first product, PROVIGIL(R) (modafinil) Tablets [C-IV], was launched with an orphan drug designation for narcolepsy in 1999. Other Cephalon therapies with orphan drug designation include TRISENOX(R) (arsenic trioxide) injection and CEP-701 (lestaurtinib), which is i...
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