Aluminum-oxide nanopore beats other materials for DNA analysis
CHAMPAIGN, Ill. Fast and affordable genome sequencing has moved a step closer with a new solid-state nanopore
sensor being developed by researchers at the University of Illinois.
sensor, made by drilling a tiny hole through a thin film of aluminum oxide, could ultimately prove capa...
Story tips from the Department of Energy's Oak Ridge National Laboratory, September 2008
...elop a high speed DNA sequencing device. Using the Paul trap to manipulate DNA between nanotube electrodes could result in a lower cost alternative to nanopore
sequencing, which works by moving strands of DNA through a small hole in a membrane. Most of the work is being conducted in collaboration with the Mar...
NHGRI seeks DNA sequencing technologies fit for routine laboratory and medical use
.... The goal of this group is to design and optimize nanopore
technology using novel electronic control and sensing methods to eventually lead to a nanopore
detector chip capable of sequencing a mammalian ge...le
$830,000 (3 years)
Exploration of Solid-state nanopore
Reading Labeled Linear DNA Sequence
The goal of...
New technique could dramatically lower costs of DNA sequencing
...A by driving the molecule back and forth through a nanopore
capacitor in a semiconductor chip. The technique c... that back-and-forth motion of a DNA molecule in a nanopore
capacitor 1 nanometer in diameter produces an elec...tional Center for Supercomputing Applications, the nanopore
capacitor consists of two conducting layers of dop...
NHGRI aims to make DNA sequencing faster, more cost effective
...hroughput DNA Sequencing Using Design Polymers and nanopore
This group along with their industrial... previously funded through this program in which a nanopore
is used to simultaneously detect electrical and fl...versity, Cleveland,$815,000 (3 years),"Large-Scale nanopore
Arrays for DNA Sequencing"
This team will aim ...
MIT's molecular sieve advances protein research
...ssor of Electrical Engineering and Biological Engineering at MIT. "With our nanopore
system, we control the pore size precisely, so we can control the sieving p...s. The MIT researchers were, however, able to confirm Ogston sieving in the nanopore
"This is the first time anyone was able to experimentally confir...
Nanopore method could revolutionize genome sequencing
... always fluctuate so much as it passes through the nanopore
that measuring the current would not give us any i... hurdles to overcome because no one has yet made a nanopore
with the required configuration of electrodes, but...re someone successfully assembles the device. The nanopore
and the electrodes have been made separately, and ...
NHGRI expands effort to revolutionize sequencing technologies
... is a collaborative effort between two laboratories that have experience in nanopore
research, protein engineering and molecular recognition. The group will eng...cule using a type of silicon integrated circuit. The circuit incorporates a nanopore
mechanism with a molecular trap that forces the DNA molecule to oscillate b...
DNA gripped in nanopores
...er Serge Lemay, has now shown for the first time how the gel influences the movement of the DNA. The researchers drove a single DNA molecule through a nanopore
in order to analyze the forces on the DNA. The results of the research were published on March 29 in Nature Physics .
The movement of DNA under th...
Making a good impression: Nanoimprint lithography tests at NIST
...could pattern the film accurately and do so without destroying the delicate nanopore
In a paper published last fall,** NIST materials scientists ad...* they extend this work to study the effect of the embossing process on the nanopore
structure in the glass. Using a combination of techniques to measure the di...