DNA Molecules Used To Assemble Nanoparticles
University of Michigan researchers have developed a faster, more efficient way to produce a wide variety of nanoparticle drug delivery systems, using DNA molecules to bind the particles together. Nanometer-scaled dendrimers can be assembled in many configurations by using attached lengths of single-stranded DNA molecules, which naturally bind to other DNA strands in a highly specific fash...Imaging Lymph Nodes with Nanoparticles
Accurate staging of cancers is one of the most important parts of thework up of patients for both prediction of prognosis and determinationof the most appropriate treatment. And an essential part of this workup is assessing wh...Probing The Promise And Perils Of Nanoparticles
For all its promise, the prospect of using nanoparticles in biomedical applications and consumer products has raised concerns about possible harmful effects of the miniscule materials. Scientists at the University of Michigan are addressing those concerns by investigating how certain kinds of nanoparticles damage cell membranes—enough to cause cell death in some cases—and how the damage can be pr...Probing the promise and perils of nanoparticles
For all its promise, the prospect of using nanoparticles in biomedical applications and consumer products has raised concerns about possible harmful effects of the miniscule materials. Scientists at the University of Michigan are addressing those concerns by investigating how certain kinds of nanoparticles damage cell membranes---enough to cause cell death in some cases---and how the damage can b...Nanoparticles offer new hope for detection and treatment
Specially designed nanoparticles can reveal tiny cancerous tumors that are invisible by ordinary means of detection, according to a study by researchers at Washington University School of Medicine in St. Louis. The researchers demonstrated that very small human melanoma tumors growing in mice--indiscernible from the surrounding tissue by direct MRI scan--could be "lit up" and easily locate...MRI with nanoparticles highly sensitive in detecting prostate cancer metastases
High-resolution MRI with magnetic nanoparticles is highly sensitive in detecting clinically occult lymph-node metastases in prostate cancer, according to a new report. In fact, routine use of this modality preoperatively could obviate many unneeded surgeries.// The nanoparticles, which are given intravenously 24 hours before scanning, work by binding to lymphatic cells. The particles only...Gold Nanoparticles: Agents For Noninvasive Cancer Therapy
Gold nanoparticles are potential and very practical agents in therapeutic applications. Researchers from the University of California, San Francisco and Georgia Institute of Technology, writing Cancer Letters // (Available online 28 September) demonstrate the efficiency of gold nanospheres as photothermal agent by selectively delivering gold nanoparticles to oral carcinoma cells that overexpress...Alzheimer's Can Be Slowed Down By Gold Nanoparticles
A combination of radiation and gold nanoparticles can help in slowing down the progress of Alzheimer's disease, according to a research conducted by scientists from Spain and Chile. The healthy brain // cells will not be affected by this. According to their study, to be published in the American Chemical Society's Nano Letters, the technique, a type of molecular surgery, has the potential to d...Gold Nanoparticles Are Good Detectors Biological Toxins
Researchers at the University of East Anglia have found that gold nanoparticles are very effective detectors of biological toxins//. These particles they say reveal the presence of poisons far faster than existing techniques that often involve shipping samples back to a lab. This they hope would help in aiding investigations at crime scenes. Researchers led by Professor David Russell...Scientists To Study Effect Of Nanoparticles On Liver
University of Edinburgh researchers will study the effect of tiny nanoparticles on the health of the liver. These nanoparticles are found in pollution// from traffic exhaust and are also used in making household goods such as paint, sunblock, food, cosmetics and clothes. The scientists will assess if these particles damage liver cells. Nanoparticles are atoms and molecules 80,000 times...Vision Deficit in Retinitis Pigmentosa Mice Corrected with DNA Nanoparticles
CLEVELAND--(BUSINESS WIRE)--Jun 4, 2007 - Copernicus Therapeutics,Inc. announced today that a research team at University of OklahomaHealth Sciences Center, led by Dr. Muna Naash, Professor of CellBiology, demonstrated that Copernicus' DNA nanoparticles correctedvision defects in a mouse model of retinitis pigmentosa (RP). Thesefindings were presented at the American Society of Gene Therapy...Evidence of Nanoparticles Found in Plaque-Filled Arteries
ROCHESTER, Minn., April 30. 2007-- Scientific evidenceincreasingly links arterial calcification to the presence ofnanosized particles -- so small that some scientists questionwhether a nanoparticle can live and, if so, play a viable role incausing disease. A new Mayo Clinic study cites evidence showing the presence ofnanoparticles near plaque-filled arteries in animal models....