Anti-Craving Drug, Naltrexone Helps Women Quit Smoking
A new study finds that the anti-craving drug, Naltrexone may lessen cessation-related weight gain and negative moods and women who are trying to quit smoking appear //to benefit more than men. As a first step towards individualized medicine, scientists are focusing on gender differences in nicotine...Addiction Drug May Help Ease Fibromyalgia
... In small study, naltrexone offered some women relief FRIDAY, Apri...y News) -- Low doses of an inexpensive drug called naltrexone -- already used for years to treat drug addiction ...e drugs." Younger said he got the idea to study naltrexone after hearing that some other doctors had success ...Suppressing the compulsion to steal
...d randomized them to receive treatment with either naltrexone or placebo. naltrexone is a drug that blocks the effects of endogenous op.... They found that after eight weeks of treatment, naltrexone was able to reduce the urges to steal and stealing...Drug commonly used for alcoholism, drug addiction, curbs urges of compulsive stealers
...d an eight-week, double-blind study of 25 men and women ages 17-75, who spent an average of at least one hour a week stealing. Those who took the drug naltrexone (mean dose of 117mg/day) reported significantly greater decline in stealing behavior compared to those taking placebo. The research is published in ...Hormone Drug May Help Drinkers Stay Sober
...humans for the treatment of hyperprolactinemia." Only three medications have FDA approval for treating alcohol dependence -- disulfiram (Antabuse), naltrexone (Depade, ReVia), and acamprosate (Campral). The U.S. National Institutes of Health estimates that almost 18 million people in the United States --...UCSF Gallo Study Finds Hormone Disorder Drug Could Help Drinkers Stay Sober
...t, according to the National Institutes of Health. But there are just three medications approved to treat alcohol dependence -- disulfiram (Antabuse), naltrexone (Depade, ReVia), and acamprosate (Campral). Lead author of the study is Sebastien Carnicella, PhD, postdoctoral fellow at the Gallo Center. Co-aut...King Pharmaceuticals To Acquire Alpharma for Approximately $1.6 Billion
...morphine sulfate extended-release with sequestered naltrexone hydrochloride), both of which are designed to resi...morphine sulfate extended-release with sequestered naltrexone hydrochloride) Capsules ALO-01(morphine sulfate extended-release with sequestered naltrexone hydrochloride) Capsules (EMBEDA(TM)), Alpharma's p...Prescribed Meds Still Best Treatment for Alcoholism
...heir relapse rates appeared to be more a function of inadequate exposure to naltrexone and less influenced by CBI," he added. Overall, specialized CBI did not ...ion adherence rates," Zweben said. The findings show that combing MM and naltrexone could benefit a large percentage of alcohol-dependent patients. "Alcohol...Scientific poster abstracts from the 24th annual meeting of the American Academy of Pain Medicine
... 2005 Treatment Episode Data Set (TEDS) 157 Evaluation of Lacosamide in Diabetic Neuropathic Pain Trials 158 A Pilot Study to Select a Dose of naltrexone Hydrochloride That Will Reduce Subjective Euphoric Effects of Oxycodone Hydrochloride in Non-Dependent, Opioid-Preferring Subjects 159 Tapentadol ...Orexigen(R) Therapeutics Announces Changes to Its Clinical Programs and Management Team
...proof-of-concept Phase 2 trials for OREX-003 (zonisamide and olanzapine to mitigate antipsychotic-associated weight gain) and OREX-004 (fluoxetine and naltrexone to reduce symptoms of obsessive- compulsive disorder) will be discontinued effective immediately. The Company intends to maintain its intellectual pr...Orexigen(R) Initiates Second Phase IIb Empatic(TM) Trial on Schedule
...besity product candidate, Contrave(R), is a combination of bupropion SR and naltrexone in a proprietary SR formulation that also appears to result in improved tolerability compared to the legacy naltrexone IR formulation. Contrave currently is being studied in four Phase III clini...Orexigen(R) Therapeutics Announces First Quarter 2009 Financial Results
...t (p<0.001). Contrave was generally well tolerated by patients, with an overall safety profile that was consistent with its individual components, naltrexone and bupropion. The most frequently observed treatment-emergent adverse events for patients on study drug were nausea, headache, constipation and dizz...Orexigen(R) Therapeutics Issued a Key Fourth U.S. Patent on Contrave(R)
...n patent (U.S. Patent No. 7,375,111) which was issued by the USPTO in May 2008 and broadly covers sustained release (SR) compositions of bupropion and naltrexone combined in a single dosage form. The Weber/Cowley methods patent will provide protection for Contrave through mid 2024. "The issuance of this ...Orexigen(R) Therapeutics Announces Third Quarter 2008 Financial Results
...008, which covers SR compositions of bupropion and naltrexone combined in a single dosage form through March 202...ivity. OREX-004 is a proprietary SR formulation of naltrexone plus fluoxetine. The Phase 2a clinical trial, NF- ...xone successfully achieved key objectives (lowered naltrexone Cmax, increased Tmax, comparable AUC). Additionall...New MedPredict Report Suggests Market for Alcoholism Therapies is Underestimated
...rding to this physician panel, there are a number of factors stymieing biopharmaceutical companies, including the lackluster commercial performance of naltrexone and acamprosate, a lack of clear FDA guidance on trial design and resulting indications, the stigma associated with alcoholism and associated corporat...DNA Predicts Reaction to Drug That Fights Alcohol Dependence
...ing gratification from alcohol. Not only did patients who were treated with naltrexone and have the Asp40 gene variant go without harmful drinking for a longer pe...al without the therapy. Gene variant carriers of all ethnicities who took naltrexone were more likely than their counterparts to have a good clinical result. Ho...