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NTP in Medical News

FreePatentsOnline Launches the CitePatents Program : Making it Easy for Bloggers and Journalists to Reference Patents, and Add Patent Search to Websites

...the firm behind the BlackBerry, may have avoided its patent infringement lawsuit and settlement payment of $612.5 million to Annandale, Virginia-based ntp by simply searching CitePatents.com or FreePatentsOnline.com for an electronic mail system with RF communications to mobile processors patent. The res...

Newly approved ocular safety methods reduce animal testing

...use of live animals for eye safety testing by 10 percent or more," stated William Stokes, D.V.M., the executive director of ICCVAM and director of the ntp Interagency Center for the Evaluation of Alternative Toxicological Methods NICEATM). "More importantly, the use of these tests will eliminate the test...

Juvenile Products Manufacturers Association Supports Safety of Baby Bottles

...Program's (NTP) Center for the Evaluation of Risks to Human Reproduction. Following an expert panel review last year, this week's release of the draft ntp Brief on bisphenol A (BPA) affirms that there are no serious or high level concerns for adverse effects of BPA on human reproduction and development. ...

Draft National Toxicology Program Report Supports Safety of Bisphenol A

...review last year, yesterday's release of the draft ntp Brief on bisphenol A affirms that there are no ser...ientific and government bodies worldwide." The ntp Brief confirms that human exposure to bisphenol A ...esses one of the key areas identified in the draft ntp report." Many independent scientific and gover...

Rodent study finds artificial butter chemical harmful to lungs

...he two major components, diacetyl and another compound called acetoin. The ntp studies will help pinpoint more definitively the toxic components of artifi...lavoring and potentially help identify biomarkers for early detection. The ntp data will then be shared with public health and regulatory agencies so they...

Plan expedites alternatives to animal testing

...cedures so animals experience less pain and distress, or replacing animals with non-animal systems. William Stokes, D.V.M., director of NICEATM, the ntp office at the National Institute of Environmental Health Sciences (NIEHS) that administers ICCVAM, highlighted some of the progress made since ICCVAM ...

Hexavalent Chromium in Drinking Water Causes Cancer in Mice

...cause cancer in animals when administered orally," said Dr. Michelle Hooth, ntp study scientist for the technical report. During the study, male a... taken up by the cells in many tissues and organs," said Hooth. The ntp began work on this compound after gaining inputs from the public and a pane...
NTP in Biological News

Plastics chemical retards growth, function of adult reproductive cells

...ratory animals in some studies, such adverse effects "are observed at levels of exposure that far exceed those encountered by humans." However, the ntp reported that laboratory studies that showed effects in animals exposed to low doses of BPA led it to have "some concern for effects on the brain, beh...

Countries unite to reduce animal use in product toxicity testing worldwide

...lternatives to animal testing," said Linda Birnbaum, Ph.D., director of the ntp and National Institute of Environmental Health Sciences, part of the Nation... resources." Birnbaum signed as the U.S. representative on behalf of the ntp Interagency Center for the Evaluation of Alternative Toxicological Methods ...

Hear about emerging trends in toxicology research

...ew NIEHS/NTP director; hear about the new criteria ntp will be using to evaluate non-cancer studies; lear... Contact: To arrange an interview with NIEHS or ntp scientists, please contact Robin Mackar at 919-541...ll be held at the Baltimore Convention Center. ntp Criteria for Hazard Identification in Non-Cancer S...

NTP finalizes report on Bisphenol A

...ould result in clear adverse health effects," said ntp Associate Director John Bucher, Ph.D. "But we have...mmary gland or accelerate puberty in females. The ntp expressed "negligible concern" that exposure of pr...birth weight and growth in their offspring. The ntp also expressed "negligible concern" that exposure ...

NAS report offers new tools to assess health risks from chemicals

...ogy development, refined standardization and validation, so these tools can be even more useful to regulatory agencies, says Portier. The NIEHS and ntp have been steadily increasing the use of toxicogenomic and other technologies derived from the molecular biology revolution, said Samuel H. Wilson, M....

Hexavalent chromium in drinking water causes cancer in lab animals

... inhalation exposure," said Michelle Hooth, Ph.D., ntp study scientist for the technical report. "We now ...of Environmental Health Sciences (NIEHS) after the ntp Board of Scientific Counselors Technical Reports R...ontaining hexavalent chromium that was used in the ntp studies. The...

Nobel Laureate finds 'elegant' explanation for DNA transcribing enzyme's high fidelity

...form an extensive network of interactions with the ntp and other parts of the enzyme. Those interactions ...mponents of the growing RNA chain together. If the ntp is even slightly misaligned, Kornberg said, those .... The trigger loop mechanism therefore couples ntp recognition and catalysis, ensuring the fidelity o...

High fidelity keeps human DNA assembly line humming

... RNA. Burton's insight was to discover that the ntp bases preload to the DNA template several steps be...idea contradicts the prevalent view of how RNA and ntp bases hook up. Preloading of NTPs hints at a previ...ation to maintain accuracy of RNA synthesis. If an ntp doesn't match up properly with DNA, the system sta...
NTP in Biological Technology

NIH collaborates with EPA to improve the safety testing of chemicals

... Research and Development which houses the NCCT; and John R. Bucher, Ph.D., ntp associate director describe the possibility of shifting from reliance on a...ngths and establishes a long-term, multiple U.S. federal agency commitment. ntp will contribute thousands of compounds for testing. NTPs animal toxicology...

Flawed Routers Flood UW Server

...destined for one of the campus' public Network Time Protocol (NTP) servers. ntp servers are used to synchronize computer clocks on the Internet. The flood ...t page for their RP614 router , points out that some products use public ntp sources that can cause "spikes," and gives a firmware fix for a series of p...

Nuclease Protection Assays: The Basics

...), a 1:50 dilution of labeled ntp with "cold" ntp should be used to increase th...1:10,000 dilution with "cold" ntp should be used. NPA Analysis Ambion's NPA...

Synthesize High Yields of Biotinylated aRNA

...de is supplied as a pre-mixed ntp at an optimized ratio, providing convenient, ...50 ng total RNA Optimized ntp mix containing biotinylated U...t. Only a single biotinylated ntp is used because studies at Ambion and ...

Better RNA Amplification

..., incorporation efficiency varies for different labels (e.g. Cy3 ntp vs Cy5 NTP). These problems can be avoided by incorporating an amino allyl ntp into the aRNA and subsequently coupling its reactive amino group...

aRNA Synthesis and Labeling for Array Analysis

..., incorporation efficiency varies for different labels (e.g. Cy3 ntp vs. Cy5 NTP). These problems can be avoided by indirect labeling, whereby an amino allyl ntp is incorporated into the aRNA, and the reactive amino group is s...

Trouble-shooting: Low yield

...expected concentration of 10 mM. Using 0.05 M Tris-base and pH paper adjust the pH to 7.0. Dilute an aliquote of the neutralized ntp or dNTP appropriately and read the optical density at the wave lengths given in the following table. Calculate the actual concen...
NTP in Biological Dictionary

Ribonucleotides

...inding ... Ribonucleotides are found in RNA (ribonucleic acid) and sometimes in DNA. ... The ribonucleotides must also be phosphorylated to the ntp level to provide the ... ... have been able to show how RNA's component molecules, called ribonucleotides , ... " Ribonucleotides are simply an ...

Citric acid cycle

... a branched, non-cyclic mode under ... The first reaction of the citric acid cycle is the condensation of acetyl-CoA ... to generate the only ntp produced directly in the citric . acid cycle . ... The citric acid cycle takes place within the mitochondria in eukaryotes, and ... It ...
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