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NCBI in Medical News

Scientists identify new congenital neutropenia syndrome and causative gene mutation

...ed for the study using the SCN International Registry. A researcher from ncbi analyzed data on the children to look for suspect genes, and determined tha... of interest was among 258 on chromosome 17. Further positional analysis at ncbi reduced the number of suspect genes to 36. A big break in the research came...

ABC and NMDP Partner to Meet Growing Need for Stem Cell and Cord Blood Transplants, Assure Funding for Cord Blood Network, Encourage Minority Donor Recruitment

...h ensures the availability of cord blood units collected and increases the diversity of the National Cord Blood Inventory (NCBI). The objective of the ncbi is to increase the inventory by 150,000 cord blood units. Three ABC members -- New York Blood Center, South Texas Blood and Tissue Center, and Puget S...

Genome-wide association study on Parkinson's disease finds public home at NIH

... in significantly more data being available through dbGaP and will greatly enhance the discovery opportunities for researchers mining these data, said ncbi Director David Lipman, M.D. Researchers interested in accessing the Mayo-Perlegen LEAPS Collaboration study dataset should go to dbGaPs Web site a...

Researchers provide genetic associations from a genome-wide scan for cardiovascular disease traits

...l associations and allowing the data to be explored in the context of other ncbi genomic resources. We are excited by the possibilities of genome-wide ... the FHS 100K study or develop new hypotheses for further research. The ncbi web site has the added advantage of linking into dozens of other databases,...
NCBI in Medical Dictionary

Chromosome

...a) the telomere region from one original chromosome ... Fig. 1: Chromosome #2, enlarged, comparing all four species. Fig. 2: Chromosome #2, from ncbi Map ... Chromosome : a very long DNA molecule and associated proteins, that carry ... A chromosome is formed from a single DNA molecule that co...
NCBI in Biological News

7th annual [BC]2 Basel Computational Biology Conference 'Molecular Evolution' June 18-19, 2009

...National Center for Biotechnology Information (NCBI) at the National Institutes of Health (NIH) and is active in Computational Biology and Genomics at ncbi since 1991. He is also editor of the Genome Analysis section in Trends in Genetics. Other speakers include: Manolis Dermitzakis, Wellcome Trust ...

Novel publishing approach puts textbook in more hands

...ycobiology , published in print in 1999, was released online as part of the ncbi Bookshelf in 2003. The content of the second edition of Essentials of Glyc... edition of Essentials of Glycobiology online," wrote David Lipman, M.D., ncbi Director, in the preface to the new edition. "These readers are geographic...

American Society for Microbiology honors David J. Lipman

...s. He also led the way in creating powerful bioinformatics software tools that have revolutionized discovery research. In his role as Director of the ncbi at NIH, he has had a profound impact on the progress of biological science and biotechnology around the world by providing easy access to data, tools,...

SLIM Search Launches Academic Pricing Program

...imary search phase, it can be paired with any secondary alignment phase. The first release of SLIM is paired with BL2SEQ (the alignment phase from the ncbi Blast package). The final result can be identical to whatever is desired, simply by selecting a different alignment phase. A Revolutionary Solution ...

Researchers identify gene involved in dog size

...a Cruz; and at the Broad Institute website ( www.broad.mit.edu/mammals/dog ). The SNPs may be viewed at dbSNP ( www.ncbi.nlm.nih.gov/projects/SNP ) at ncbi and at the Broad Institute website ( www.broad.mit.edu/mammals/dog/ ). ...

U-M scientists say fused genes trigger the development of prostate cancer

...earch scientist Eran Halperin at ICSI, worked with ncbi scientists Michael Feolo and Stephen Sherry to inf...isease. All of the HapMap data is deposited in ncbi and was made available to the California researche...me there is a new release of data deposited in the ncbi database." "By reducing the waiting time to ...

California computer scientists double volume of data in NIH biotech repository

...earch scientist Eran Halperin at ICSI, worked with ncbi scientists Michael Feolo and Stephen Sherry to inf...isease. All of the HapMap data is deposited in ncbi and was made available to the California researche...me there is a new release of data deposited in the ncbi database." "By reducing the waiting time to ...

‘Blue Brain?project explores thought at molecular level

...anish Pig Genome Project can be found at: http://www.biomedcentral.com/1471-2164/6/70 and the genome sequence data are immediately accessible from the ncbi Trace Repository (Center name: "SDJVP"; Project name: "Sino-Danish Pig Genome Project") and GenBank, a public DNA sequence database of the US National...

Public release of pig genomic sequences

...anish Pig Genome Project can be found at: http://www.biomedcentral.com/1471-2164/6/70 and the genome sequence data are immediately accessible from the ncbi Trace Repository (Center name: "SDJVP"; Project name: "Sino-Danish Pig Genome Project") and GenBank, a public DNA sequence database of the US National...
NCBI in Biological Technology

FlexiPlate siRNA

...orporates exciting new features (Figure 2). New design features: siRNA target sequence from up-to-date ncbi databases siRNAs are designed against the most up-to-date gene sequences from the NCBI. Using the latest sequence information ...

Matched siRNAs and Assays: Ambion + Applied Biosystems = RNAi Success

...com/catalog/CatNum.php?16704"> Silencer Pre-designed siRNAs for >34,000 human, mouse, and rat genes in the ncbi RefSeq database eliminate costly and time-consuming siRNA design, synthesis, and testing steps. Similarly, A...

Cenix-Designed siRNAs for 95% of Human and Mouse Genomes

...hoice is up to you. We can also use the algorithm to design siRNAs to genes in other organisms listed in the ncbi database, or to design siRNAs to target a sequence that you provide. And sequence information is included as...

siRNA Design Guidelines

...-17 contiguous base pairs of homology to other coding sequences. We suggest using BLAST, which can be found on the ncbi server at: www.ncbi.nlm.nih.gov/BLAST . 3. Design appropriate controls. ...

Low Abundance cDNA Cloned Using Stratagenes Human Universal cDNA Library

...equence information from very limited amounts of protein, which can be used to screen the wealth of information available in the ncbi databasesincluding both nonredundant and Expressed Sequence Tag (EST) databases. In the case of a novel protein, identifying the...
NCBI in Biological Products

DeCypher Biocomputing Solutions from TimeLogic, a Brand of Active Motif, Inc.

Description:...cards to speed compute-intensive bioinformatics analyses. With DeCypher, you can perform searches like these from your desktop: BLAST 300,000 ESTs vs ncbi NT database in under 6 days Align BAC-sized queries (~250 kb) to genomic DNA Use HMM analysis to compare 100,000 sequences to PFAM in 5 hours Map...
Company:TimeLogic, a Brand of Active Motif, Inc.

Geneious from Biomatters Ltd

Description:... and more; all in a single application. Retrieve sequences from several ncbi databases, Uniprot, sort and filter them in real-time Organize your data h...rapidly searching, filtering and sorting Provides up-to-date articles from ncbi PubMed as they become available, links to full articles, Google scholar Se...
Company:Biomatters Ltd
NCBI in Biological Definition

Apoptosis

...information search engine provided by the US National Center for Biotechnology Information ( [27] ). Entrez Bookshelf is a service provided by the ncbi in collaboration with book publishers [28] . freebooks4doctors promotes free access to medical books ( [29] ) PubMed Central (PMC), provided b...

Biology

...echnologies - List of conservation topics Biomedical topics A to E - F to J - K to O - P to T - U to Z External links ncbi Open-Access Books EverythingBio : An online source for everything biology related. Kimball's Biology Pages : An online searchable textbook...

Bioinformatics

... The computational biology tool best-known among biologists is probably BLAST , an algorithm for searching large sequence (protein, DNA) databases. ncbi provides a popular implementation that searches their massive sequence databases. Computer scripting languages such as Perl and Python are ofte...

BLAST

...program can either be downloaded and run as a command-line utility "blastall" or accessed for free over the web. The BLAST web server, hosted by the ncbi , allows anyone with a web browser to perform similarity searches against constantly updated databases of proteins and DNA that include most of the ne...

Genetic code

...han today. 2 References There are several books available online that go into great detail on this topic. They are available through the ncbi Bookshelf , maintained by the United States National Institutes of Health . In particular the following books would be useful to consult: Griff...

Bioinformatics

... The computational biology tool best-known among biologists is probably BLAST , an algorithm for searching large sequence (protein, DNA) databases. ncbi provides a popular implementation that searches their massive sequence databases. Computer scripting languages such as Perl and Python are ofte...

Expressed sequence tag

...tides . ESTs are also a useful resource for designing probes for DNA microarrays used to determine gene expression . External links The ncbi Handbook, Part 3, Chapter 21 has a very nice overview. ...

Genetic code

...han today. 2 References There are several books available online that go into great detail on this topic. They are available through the ncbi Bookshelf , maintained by the United States National Institutes of Health . In particular the following books would be useful to consult: Griff...

Immune system

... A standard textbook on the immune system is Immunobiology , by Charles Janeway , et al. The paperback of the sixth edition is ISBN 0815341016 . ncbi makes the 5th edition availiable electronically at [2] . See also antigen /antigenic determinant / epitope / hapten / memory cell au...

Retrovirus

...dge of retroviruses, this is no longer appropriate. See also sarcoma and leukaemia HIV External links Retroviruses ncbi retrovirus book online ...
NCBI in Biological Dictionary

NCBI

The National Center for Biotechnology Information ( NCBI ) is part of the United States National Library of Medicine (NLM), a branch of the National Institutes of Health. The NCBI is located in Bethesda, Maryland and was... National Center for Biotechnology Information , part of the U.S. Nat...

Synteny

...cumstances where a pair of genes are located on ... Synteny map. Human ncbi build 31 vs. Mouse ncbi build 30. Conserved ... http://kp03.iis.sinica.edu .tw/ synteny /supplement...

Sequence

...wer gating & multi-Vt,active power, ... Query sequence (s) to be used for a BLAST search should be pasted in the 'Search' text area. ... These ncbi sequence identifiers have a very specific syntax as ... Navigation through sequence . Default displays. Representative displays ... The region o...

RNAi

...al screening pools. miR-express lentiviral ... pLKO.1 Lentiviral shRNA Libraries from the RNAi Consortium (TRC) RNAintro shRNA Starter Kits ... ncbi database of RNAi reagents and experimental results generated using ... RNAi probes ... RNA interference ( RNAi ) is mechanism for sequence-speci...

Phylogenetics

...ology phylogenetics is the... Phylogenetics Publications. In biology, phylogenetics (Greek: phyle = tribe, race and genetikos = relative ... ncbi - Systematics and Molecular Phylogenetics ... Oxford University Press UK - dictionaries, educational, academic, and scholarly books, journals, .....

Organelles

...lles are small structures within cells that perform dedicated functions. As the name implies, you can think of organelles as small organs. ... ncbi Organelle Genome Resources is a collection of organelle genomic sequences that is a part of the Entrez Genomes, which provides curated sequence ...

Organelle

... Organelle at Dictionary.com a free online dictionary ... Some organelles , such as mitochondria and chloroplasts, have their own genome ... ncbi Organelle Genome Resources is a collection of organelle genomic sequences that is a part of the Entrez Genomes, which provides curated sequence ...

Nucleotide

...y Pui-Yan Kwok. Reagents for Glycoside, Nucleotide , and ... Site for the EMBL database including documentation and how to submit data to EMBL ... ncbi - The Nucleotide Sequence Database is produced in collaboration with ... nucleotide Databases, ASD, ATD, EMBL-Align, EMBL-Bank, EMBL-CDS, Ensem...

Multi-gene family

... Patatins encoded by a multi - gene family are one of the major storage ... patatin multi - gene family in the potato were downloaded from the ncbi database ... Chromosomal localization of the spiggin multi - gene family in threespine stickleback. Localization of the spiggin multi - gene ...

Genomic clone

... The ncbi Clone Registry is a database that integrates information about genomic clones and libraries, including sequence data, genomic position, and ...
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