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NAADP in Biological News

Second messenger NAADP shows fast, dose-related impact on satiety cycle

One traditional approach to pharmaceutical design uses so-called "first messengers" ?hormones, other natural facilitators or synthetic products ?to initiate various cellular cascades for the desired physiological effect. To date, despite concerted efforts at all levels of research, this approach ha...

Canadian scientist mines drugs database for new diabetes treatment

...found after information about the natural chemical naadp was entered into the computer system and cross ref...ng Ned-19 in experiments they have discovered that naadp plays a crucial role in insulin secretion and ther... them diabetes! But now that we know how important naadp is we can start to look for drugs that work with...

Scientists mine drugs database for new diabetes treatment

...found after information about the natural chemical naadp was entered into the computer system and cross ref...ng Ned-19 in experiments they have discovered that naadp plays a crucial role in insulin secretion and ther... them diabetes! But now that we know how important naadp is we can start to look for drugs that work with...
NAADP in other areas

NAADP

Nicotinic acid adenine dinucleotide phosphate, also known as NAADP+, is a nucleotide very similar to NADP, with the nicotinamide replaced with a niacin molecule. NAADP is one of the most potent Calcium signalling messenger...

NAADP receptors in Ca2+ signalling

Commentary on 'Calcraft et al. (2009) NAADP mobilizes calcium from acidic organelles through two-pore channels. Nature 459 (7246):596-600.

Obesity Drug? - 'Second messenger' NAADP shows fast, dose-related ...

One traditional approach to pharmaceutical design uses so-called first messengers - hormones, other natural facilitators or synthetic products - to initiate various ...

Essential requirement for two-pore channel 1 in NAADP-mediated calcium ...

Essential requirement for two-pore channel 1 in NAADP-mediated calcium signaling ... Nicotinic acid adenine dinucleotide phosphate (NAADP) is a widespread and potent ...

A transport mechanism for NAADP in a rat basophilic cell line ...

NAADP is a second messenger that releases Ca2from intracellular stores. ... NAADP transport is Naand Ca2dependent, is partially blocked by dipyridamole, but ...

Citing Articles via HighWire

In contrast, the NAADP concentration was neither elevated upon activation of the ... NAADP Mobilizes Calcium from the Endoplasmic Reticular Ca2+ Store in ...
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(Date:8/21/2014)... effective vaccination, polio is considered nearly eradicated. Each year ... scientists of the University of Bonn, together with colleagues ... that was able to resist the vaccine protection to ... outbreak in the Congo in 2010. The pathogen could ... results appear now in the magazine PNAS . ...
(Date:8/21/2014)... August 21, 2014 Glioblastoma Multiforme ... Therapeutic Approaches Target High Unmet Need in Newly ... of the Glioblastoma Multiforme (GBM) therapeutics market within ... and Japan. The report provides estimates of market ... 2020. It also covers disease epidemiology, treatment algorithms, ...
(Date:8/21/2014)... 2014 One of the emerging trends ... experience is an increasing adoption of non-invasive administration products. ... the patient through their convenient application, they find more ... a medical device used for the administration of drugs ... and paranasal sinus such as allergic and non-allergic rhinitis ...
(Date:8/21/2014)... Hospital officials, community leaders and elected officials ... new building at Mount Sinai Queens, marking the completion ... expansion and modernization project. During the event, hospital ... Kaufman, Chairman of the nearby Kaufman Astoria Studios, for ... will be named. The project, which began late ...
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(Date:8/19/2014)... nutrition rating systems be used in supermarkets to encourage ... researchers sought to answer that very question by tracking ... the Guiding Stars System to rate the nutritional value ... Food and Brand Lab,s David Just, PhD, and Brian ... the sales records of over 150 Hannaford Supermarkets in ...
(Date:8/19/2014)... Long-Term Ecological Research and Network-Level Science, , Imagine if ... range of ecosystems was responding to global changes in ... if it coupled multiple decades of information about ecological ... models from dozens of different ecosystem types. , ... Ecological Research (LTER) Network, which will soon celebrate its ...
(Date:8/19/2014)... leprosy and tuberculosis live side-by-side. Worldwide there are ... with nearly all of them occurring where tuberculosis ... Calmette-Guerin, or BCG, provides only partial protection against ... vaccine is needed to combat both diseases. UCLA-led ... both diseases., In a study published in the ...
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