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NAADP in Biological News

Second messenger NAADP shows fast, dose-related impact on satiety cycle

One traditional approach to pharmaceutical design uses so-called "first messengers" ?hormones, other natural facilitators or synthetic products ?to initiate various cellular cascades for the desired physiological effect. To date, despite concerted efforts at all levels of research, this approach ha...

Canadian scientist mines drugs database for new diabetes treatment

...found after information about the natural chemical naadp was entered into the computer system and cross ref...ng Ned-19 in experiments they have discovered that naadp plays a crucial role in insulin secretion and ther... them diabetes! But now that we know how important naadp is we can start to look for drugs that work with...

Scientists mine drugs database for new diabetes treatment

...found after information about the natural chemical naadp was entered into the computer system and cross ref...ng Ned-19 in experiments they have discovered that naadp plays a crucial role in insulin secretion and ther... them diabetes! But now that we know how important naadp is we can start to look for drugs that work with...
NAADP in other areas

NAADP

Nicotinic acid adenine dinucleotide phosphate, also known as NAADP+, is a nucleotide very similar to NADP, with the nicotinamide replaced with a niacin molecule. NAADP is one of the most potent Calcium signalling messenger...

NAADP receptors in Ca2+ signalling

Commentary on 'Calcraft et al. (2009) NAADP mobilizes calcium from acidic organelles through two-pore channels. Nature 459 (7246):596-600.

Obesity Drug? - 'Second messenger' NAADP shows fast, dose-related ...

One traditional approach to pharmaceutical design uses so-called first messengers - hormones, other natural facilitators or synthetic products - to initiate various ...

Essential requirement for two-pore channel 1 in NAADP-mediated calcium ...

Essential requirement for two-pore channel 1 in NAADP-mediated calcium signaling ... Nicotinic acid adenine dinucleotide phosphate (NAADP) is a widespread and potent ...

A transport mechanism for NAADP in a rat basophilic cell line ...

NAADP is a second messenger that releases Ca2from intracellular stores. ... NAADP transport is Naand Ca2dependent, is partially blocked by dipyridamole, but ...

Citing Articles via HighWire

In contrast, the NAADP concentration was neither elevated upon activation of the ... NAADP Mobilizes Calcium from the Endoplasmic Reticular Ca2+ Store in ...
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