Muscling in on type 2 diabetes
...lly occurring mutations in the gene which controls myostatin
results in doublemuscling in cattle, dogs and even... the body building community believe that blocking myostatin
is a shortcut to the Arnold Schwarzenegger body.
The flipside is that producing too much myostatin
has been linked with muscle wasting conditions suc...
Researchers discover target that could ease spinal muscular atrophy symptoms
...esearchers inhibited myostatin, a protein that limits muscle tissue growth. myostatin
activity can be reduced significantly by enabling several proteins that bind to myostatin, including follistatin. When myostatin
is inhibited, muscle mass and strength increase.
SMA is caused by the ...
Myostatin inhibitors may improve recovery of wartime limb injuries
...oldiers, researchers say.
They are studying two myostatin
inhibitors in mice with limb injuries, first to se...is enabling laboratory studies of two experimental myostatin
inhibitors: a decoy receptor and a binding protein...ns of injured limbs before and after treatment.
is primarily produced by muscle cells. Females ten...
New potential treatment for muscular dystrophy appears to be safe
...and strength. A new study, the first to evaluate a myostatin
inhibitor in patients, assessed its safety in adul...o four groups given sequentially higher doses of a myostatin
inhibitor called MYO-029 produced by Wyeth Pharmac...rts the hypothesis that systemic administration of myostatin
inhibitors provides an adequate safety margin for ...
Drugs to bulk up muscles may make injuries more likely
...for some medical conditions.
Such drugs, called myostatin
inhibitors, also are stirring interest among body ...sity of Michigan study in mice suggests that while myostatin
inhibitors may indeed bulk up muscles, they may al...scle injuries more likely.
Those interested in myostatin
inhibitors need to be aware of the fact that by do...
Hope For Patients With Muscular Dystrophy
...her tests revealed the child had a mutation in his myostatin
gene that effectively kept his body from producing the myostatin
protein, which is known to regulate muscle growth....ly as he grows up.
The original research on the myostatin
gene was conducted by researchers in 1997. They fo...
Myostatin gene could hold the key to treatment for DMD
...discovered that drugs or molecules used to inhibit myostatin
- a protein that inhibits muscle growth - might pr...h in mice with DMD is increased by the loss of the myostatin
gene. She teamed with Hopkins geneticist Se-Jin Lee to create a strain of mice lacking the myostatin
gene which were later bred with mice with DMD. The...