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Myopathy in Medical News

Inflammatory Myopathy may Indicate Intolerance to Gluten

Researchers investigate the relationship between myopathy and intolerance to gluten.// Inflammatory myopathies are immunological diseases that lead to inflammations in muscular tissue. Coeliac disease is occasionally reported in patients with inflammatory myopathies. Inflammatory myopat...

Statins May Cause Muscle Damage in Some Patients

...eir use for at least three weeks. Biopsies showed that 25 of the 44 with myopathy had muscle damage, defined as injury to 2 percent or more of the muscle fib...onary artery disease. In the new study, 41 percent of those experiencing myopathy were taking simvastatin (Zocor); 31 percent were taking pravastatin (Pravac...

Abbott and AstraZeneca Submit New Drug Application to the FDA for CERTRIAD(TM), an Investigational Treatment for Mixed Dyslipidemia

... in women who are or may become pregnant, and in nursing mothers. Cases of myopathy and rhabdomyolysis with acute renal failure secondary to myoglobinuria have... any dose level but are increased at the highest dose (40 mg). The risk of myopathy during treatment with CRESTOR may be increased with concurrent administrati...

Australian team reveals world-first discovery in a 'floppy baby' syndrome

...the Western Australian Institute for Medical Research (WAIMR) has restored muscle function in mice with one type of Floppy Baby Syndrome a congenital myopathy disorder that causes babies to be born without the ability to properly use their muscles. The currently incurable genetic diseases render most of t...

Video: CRESTOR(R) Reduced Risk of Blood Clots in the Veins

... pregnant, and in nursing mothers. Cases of myopathy and rhabdomyolysis with acute renal failure second... caution in patients with predisposing factors for myopathy (eg, age Greater Than or Equal To 65 years, inadeq...ted hypothyroidism, renal impairment). The risk of myopathy during treatment with CRESTOR may be increased wit...

CRESTOR Cuts Risk of Stroke by Nearly Half in JUPITER Study

...me pregnant, and in nursing mothers. Cases of myopathy and rhabdomyolysis with acute renal failure second... caution in patients with predisposing factors for myopathy (eg, age greater than or equal to 65 years, inadeq...ted hypothyroidism, renal impairment). The risk of myopathy during treatment with CRESTOR may be increased wit...

Study Finds Folic Acid Not Cardioprotective, Though Safe

...iated with more myopathy cases than 20mg simvastatin, although the SEARCH trial had identified a genetic variant that accounted for much of the excess myopathy risk with the higher-dose simvastatin regimen. Co-authors are the SEARCH Collaborative Group. Individual author disclosures are available on the abs...

GlaxoSmithKline Obtains Exclusive U.S. OTC Marketing Rights to MEVACOR(R) (lovastatin) from Merck & Co., Inc.

...e, in part, to inhibition of CYP3A4. The risk of myopathy is increased by high levels of HMG-CoA reductase i...ctase inhibitory activity and increase the risk of myopathy (see WARNINGS, Myopathy/Rhabdomyolysis and PRECAUT...hibitors of HMG-CoA reductase, occasionally causes myopathy manifested as muscle pain, tenderness or weakness ...

CRESTOR(R) Now Indicated to Slow the Progression of Atherosclerosis in Patients With Elevated Cholesterol

...ported with drugs in this class, including CRESTOR. These risks can occur at any dose level but are increased at the highest dose (40 mg). The risk of myopathy during treatment with CRESTOR may be increased with concurrent administration of some other lipid-lowering therapies (fibrates or niacin), gemfibrozil...

Abbott's Investigational SIMCOR(R) Offers Comparable LDL Lowering to Simvastatin and Significantly Raises HDL and Lowers Triglycerides in Phase III Study

...ur different doses of Niaspan combined with simvastatin for 24 weeks was well tolerated. There was no evidence for increased risk of hepatotoxicity or myopathy with the combination. Treating Beyond LDL Treatment of high cholesterol has long centered on the use of statins, including simvastatin, to lower LDL...
Myopathy in Medical Technology

Neurobiological Technologies' Partner, Celtic Pharma, Announces Results of XERECEPT(R) Phase 3 Clinical Program

... In addition, the NTI-0303 trial showed that use of XERECEPT(R) leads to statistically significant reductions in steroid-related adverse events of myopathy (muscle weakness) and Cushingoid syndrome. Specifically, patients demonstrated a statistically significant increase in Ileopsoas muscle strength. Th...

Pharmasset Voluntarily Halts Clinical Studies with Clevudine in Hepatitis B Infected Patients

...clevudine than patients in the QUASH studies and have reported more serious myopathy than have patients in the Pharmasset clinical trials. Given the number and ..., MPH, Pharmasset's Chief Medical Officer. "Although the number of cases of myopathy in the QUASH trials was low and the severity was mild, more severe reports ...

CRESTOR(R) Reduced CV Risk in Patients Achieving Low LDL and hsCRP Targets in New JUPITER Analysis

... pregnant, and in nursing mothers. Cases of myopathy and rhabdomyolysis with acute renal failure second... caution in patients with predisposing factors for myopathy (eg, age Greater Than or Equal to 65 years, inadeq...ted hypothyroidism, renal impairment). The risk of myopathy during treatment with CRESTOR may be increased wit...

CRESTOR(R) Reduced Risk of Blood Clots in the Veins

... pregnant, and in nursing mothers. Cases of myopathy and rhabdomyolysis with acute renal failure second... caution in patients with predisposing factors for myopathy (eg, age Greater Than or Equal To 65 years, inadeq...ted hypothyroidism, renal impairment). The risk of myopathy during treatment with CRESTOR may be increased wit...

Dramatic JUPITER Findings Fail to Sway Prescribing Behavior, Poll Shows

... A second M.D., wary of statins, objected to placing people on medications who ostensibly don't need them. "Statins have side effects such as myopathy and ED with decreased libido in men and women," he observed. "Recently they have been associated with cognitive impairment and possible early developm...

CRESTOR Demonstrates Dramatic CV Risk Reduction in a Large Statin Outcomes Study

...ecome pregnant, and in nursing mothers. Cases of myopathy and rhabdomyolysis with acute renal failure second... caution in patients with predisposing factors for myopathy (eg, age greater than or equal to 65 years, inadeq...scontinued if markedly elevated CK levels occur or myopathy is diagnosed or suspected. All patients should be ...

Idenix Announces Data Presentations at the 2007 Digestive Disease Week Meeting

...therapy may be warranted. -- Cases of myopathy have been reported with TYZEKA use several weeks to months after starting therapy. myopathy has also been reported with some other dru...eatment with these or other agents associated with myopathy should weigh carefully the potential benef...
Myopathy in Medical Definition

Proteopathy

...Keratins Corneal lactoferrin amyloidosis Lactoferrin Pulmonary alveolar proteinosis Surfactant protein C (SP-C) Critical illness myopathy (CIM) Hyperproteolytic state of myosin ubiquitination References ^ Walker LC and LeVine H (2000). "The cerebral proteopathi...
Myopathy in Medical Dictionary

Myopathy

In medicine, a myopathy is a muscular disease in which the muscle fibers do not function for any one of many reasons, resulting in muscular weakness. " Myopathy " simply means muscle disease . This meaning implies that the primary defect is within the muscle, as opposed to the...

Skeletal

...e control of fiber-type switching in skeletal muscle. ... Identification of FHL1 as a regulator of skeletal muscle mass: implications for human myopathy ... Addresses the functions of muscles and bones, bone growth, joints, and the two systems interactions. Since skeletal dysplasias are unco...

Dermatomyositis

...nd polymyositis. ... Dermatomyositis is an idiopathic inflammatory myopathy with characteristic skin manifestations. ... manifestations of dermatom...n ... Overview: Dermatomyositis (DM) is an idiopathic inflammatory myopathy (IIM) with ... Dermatomyositis ... disease of dermatomyositis is poo...
Myopathy in Biological News

Stem cell breakthrough gives new hope to sufferers of muscle-wasting diseases

...re that dramatically strengthens stem cells' ability to regenerate damaged tissue could offer new hope to sufferers of muscle-wasting diseases such as myopathy and muscular dystrophy, according to researchers from the University of New South Wales (UNSW). The world-first procedure has been successfully use...

Potential therapy for congenital muscular dystrophy

... in muscle repair and suggest direct muscle injections of laminin may serve as an exciting novel therapy for patients with alpha 7 integrin congenital myopathy and other muscle diseases." Dr. Burkin's group is "currently investigating the potential of this technology to treat Duchenne and other forms of musc...
Myopathy in Biological Technology

Abbott and AstraZeneca Expand Relationship to Include Co-Promotion of CRESTOR(R)

..., in women who are or may become pregnant, and in nursing mothers. Cases of myopathy and rhabdomyolysis with acute renal failure secondary to myoglobinuria have...t any dose level but are increased at the highest dose (40 mg). The risk of myopathy during treatment with CRESTOR may be increased with concurrent administrati...

A New President at the Head of the Genethon Laboratory

...of the AFM (French Muscular Dystrophy Association) from 1981 to 2001, Bernard Barataud is the father of three children, one of whom died from Duchenne myopathy in 1986 at the age of sixteen. Co-founder of the French Telethon in 1987, he was also the founder of Genethon in 1990 with the Nobel Prize winner Jean...
Myopathy in Biological Dictionary

Distal

...ossible that the main title of the report Distal myopathy is not the name you expected. ... Information a...d tarsometatarsal joints, move very little. ... myopathy of distal lower limbs: the clinical variant of M...hi" ... Refined mapping of the Welander distal myopathy region on chromosome 2p13 ... ... end toward ...
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