Biosite Incorporated Issues Voluntary, Nationwide Recall for Cardiac Marker Test
...ttack). The product has been recalled due to reports of low recovery of quality control samples containing Creatine Kinase MB (CK-MB), troponin I and myoglobin
on the affected lot. Although there have been no reported issues of patient misdiagnosis associated with this lot to date, low recovery may lead to r...
JCI table of contents: March 23, 2009
...tance of these data and discus other ways in which myoglobin
might affect tumor progression.
TITLE: Prevention of hypoxia by myoglobin
expression in human tumor cells promotes different...e.php?id=36579
tames tumor growth and spread
Pressured proteins: A little pressure in proteomics squeezes 4-hour step into a minute
...glob of a protein that packs a second, loose molecule inside. When they put myoglobin
under 35 kpsi in the absence of trypsin, myoglobin
lost its molecular parcel, suggesting that pressure opens up or denatures p...
Scientists get first look at how water 'lubricates' proteins
...r protein molecule, and see how those movements influence the form and function of the protein.
Zhong and his team took laser snapshots of a single myoglobin
protein -- the protein that carries oxygen inside muscle tissue -- immersed in water in the laboratory. They were able to measure how fast the water m...
Kidney diseases and their complications, an alarming scenario in the Philippines
...tack or a traumatic injury, a serious infection, or a toxic reaction to drug. In case of athletes and long runners an acute kidney failure occurs when myoglobin
is released due to lack of fluids in the body.
Chronic - In this case deterioration takes place gradually over a period of many years. But this is ve...
New test for heart attack
...nosing a heart attack is very effective and is to be implemented. They do a blood test for three cardiac enzymes - troponin 1, creatine kinase-MB, and myoglobin
- which are released into the circulation by damaged heart tissue. Along with a patient history and an echocardiogram this can rule out a heart attack...
Myoglobin in Medical Technology
Point of Care Cardiac Analyzers Yield Rapid Cardiac Marker Results
...munoassay for quantitative determination of CK-MB, myoglobin
and troponin I in whole blood and plasma specimens... Marker System, with separate test kits for CK-MB, myoglobin
and troponin I. It is also a quantitative immunof...onversion to a quantitative result. The tests for myoglobin
and troponin T yield results in 8 and 12 minutes r...
Myoglobin in Medical Products
Acute Care Myoglobin TestPak
Description: The Acute Care myoglobin
method is an in vitro diagnostic test for the measurement of myoglobin
in heparinized whole blood /plasma. Myoglobin
measurements can be used as an aid in diagnosing myocardial infarction....
Company:Dade Behring, Inc.
Myocardial Infarction - Myoglobin and Troponin Cassette
Description: Rapid Screen Tests are used by hospitals, clinics and the retail consumers to help analyze many human health conditions. The majority of these products are one-step, lateral flow membrane tests, which are offered in strip, cassette, and stick formats. Other panel formats and flow through membrane t...
Company:Biotech Atlantic, Inc.
Human Myoglobin Enzyme Immunoassay
Description: For the quantitative determination of myoglobin
concentration in human serum or plasma. The Myoglobin
ELISA test is based on the principle of a solid phase enzyme-linked immunosorbent assay. The assay system utilizes a unique monoclonal antibody directed against a distinct antigenic determinant on ...
Company:Diagnostic Automation, Inc.
Description: AxSYM Myoglobin
is a Microparticle Enzyme Immunoassay (MEIA) for the quantitative determination of myoglobin
in human serum or plasma on the AxSYM System....
CARDIAC M Myoglobin
Description: CARDIAC M Myoglobin
assay for use with the Cardiac reader analyzer. The Cardiac reader analyzer is a compact, desktop instrument. Other features include: always ready to use (stand-by mode), no manual calibration, test and batch specific data entered automatically using a code chip and barcode an...
Myoglobin - Rapid Test
Description:... The myoglobin
Insta Test is an immunochromatography based one
step in vitro test. It is d...tative determination of
myoglobin in human serum specimens. The presence of myoglobin
serum at level 100 ng/mL or higher can be detected in 5 minutes....
Triage® Cardiac Panel
Description:... The Triage® Cardiac Panel is a fluorescence immunoassay used for the rapid quantitative determination of CK-MB, myoglobin
and troponin I in ethylenediaminetetraacetic acid (EDTA) whole blood and plasma specimens. The test is used as an aid in the diagnosis of acute myocar...
Myoglobin Test Modules
Description:... A fluorogenic enzyme-linked immunoassay (ELISA) for the quantitative measurement of myoglobin
in human serum or plasma aiding in the diagnosis of acute myocardial infarction (AMI). Features : Dry chemistry-based technology for ease of use....
Company:Dade Behring, Inc.
Innotrac Aio! cardiac marker assays
Description:... on the Innotrac Aio! immunoassay system. Cardiac Troponin I (cTnI) is a marker with very high sensitivity and specificity for myocardial injury (MI). myoglobin
appears very soon following AMI. CK-MB (mass) is a traditional marker of cardiac injury....
Cardiac Reader System
Features:...results for decentralized testing as for central laboratory testing. Choosing the best parameter combination for your patients: Testing troponin T and myoglobin
allows rapid diagnosis and risk stratification in patients presenting chest pain and suspicion of myocardial infarction. If you suspect deep vein thro...
Myoglobin in Medical Dictionary
is a single-chain globular protein of 153 amino acids, containing a heme prosthetic group in the center around which the remaining apoprotein folds. It has eight alpha helices and a hydrophobic core. It has a... myoglobin
n. A single-chain, iron-containing protein found in ...
...MS, Mullins RJ. ... Crush injuries resulting in traumatic rhabdomyolysis are an important cause of ... INTRODUCTION High circulating plasma myoglobin
levels secondary to rhabdomyolysis can cause heme pigment-associated ... of crush -related injuries after ... However, minor crushing injur...
Acute tubular necrosis
...dney disorder involving damage to the tubule cells of the kidneys, resulting in acute kidney failure. INTRODUCTION High circulating plasma myoglobin
levels secondary to rhabdomyolysis can cause heme pigment-associated acute tubular necrosis (ATN), which results in an ... Acute tubular...
Myoglobin in Biological News
Natural-born divers and the molecular traces of evolution
... is important as divers may contain 10 times more myoglobin
in their muscles than terrestrial animals. The tea...cuous increase of the amino acid histidine in the myoglobin
of strong divers, which may allow the animal to de...e, they went on to study the molecular sequence of myoglobin
in small aquatic mammals such as beavers, muskrats...
Tracking sperm whales and jumbo squid
...upport their metabolism," Davis added. "Sperm whales, on the other hand, take the oxygen down with them bound to the hemoglobin in their blood and the myoglobin
in their muscles, so they don’t have to worry about hypoxia at depth."
By spending most of their time in cold, deep waters, he noted, sperm whale...
It's in your head: The brain's own globin defends you from shock and stroke
...nvolved in the brain's response to oxygen deprivation and plays a protective role against brain damage. Structurally similar to hemoglobin (blood) and myoglobin
(skeletal muscle), neuroglobin is found in neurons and is most prevalent in areas of the brain that have adapted to physiological stress, such as stro...
Myoglobin in Biological Technology
Acrongenomics on Track to Acquire Molecular Vision
...ry test using a
multi-channel device in less than 5 minutes.
Work is underway on developing cardiac markers with preliminary data
demonstrating that myoglobin
at 100ng/ml can be detected by the system
using a fluorescent immunoassay.
Acrongenomics Inc. is a publicly traded company th...
Fully Automated Nano-Electrospray Coupled with a Finnigan LCQ Deca XP Plus for Sub-fmol Proteomic Analysis
..., human hemoglobin, human macroglobulin, and horse myoglobin
were purchased from Sigma-Aldrich, St. Louis, MO, ...iscussion
The tryptic digest of horse myoglobin
was analyzed by nanospray liquid chromatography as...teins and not optimized for the detection of horse myoglobin
digest. The mass range for full mass spectrum was ...
Myoglobin in Biological Products
Myoglobin in Biological Definition
Slow twitch (type I or "red") - rich in myoglobin
(which is red and carries oxygen ), higher aero...ype II) - more anaerobic metabolism (due to less myoglobin
and mitochondria) but better at generating more po...may not lead to any muscular symptoms at all, the myoglobin
thus released may cause acute renal failure .
2 External links
List of pigments
Heme / Porphyrin based
Alpha and Beta Carotene
... A representation of the 3D structure of myoglobin
, showing coloured alpha helices . This protein was the first to have its structure solved by X-ray crystallography by Max Perutz and Sir John...
... A representation of the 3D structure of the myoglobin
protein. alpha helices are shown in colour, and random coil in white, there are no beta sheets in shown. This protein was the first to have its...
...irst protein crystal structure was of sperm whale myoglobin
, as determined by Max Perutz and Sir John Cowd...e in Chemistry . The X-ray diffraction analysis of myoglobin
was originally motivated by the observation of myoglobin
crystals in dried pools of blood on the decks of w...
Myoglobin in Biological Dictionary
...his substance decreases the affinity of hemoglobin for oxygen. ... The myoglobin
and hemoglobin page provides a description of the structure and function of these two ... myoglobin
and hemoglobin are hemeproteins whose ... Hemoglobin in vertebrates...