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Mycobacterium in Medical News

Higher drug doses needed to defeat tuberculosis, UT Southwestern researchers report

...ery skinny people 105 to 110 pounds. I haven't met many adults who are at that weight." About one-third of the world's population is infected with mycobacterium tuberculosis, the bacterium that causes TB, and as many as 2 million people die from the disease each year. TB, which is the leading cause of death am...

Eleven Veterinary Students Win Top Awards at Morris Animal Foundation's Annual Research Competition

...Wildlife, $1,500 Santiago Diaz, University of Florida D07ZO-607 : "Use of Elephant-Specific Monoclonal Antibodies and Recombinant Antigens of mycobacterium tuberculosis to Improve an ELISA Test for Elephants" IMPACT Award, $500 Ana Iris Mota Torres, University of Veracruz (Mexico) D07FE-60...

BD/PEPFAR Lab-Strengthening Initiative Marks Progress in Fight Against HIV/AIDS and TB in Sub-Saharan Africa

...s in Botswana, Ethiopia, Lesotho, Namibia, Nigeria and South Africa -- participated in ten-day courses to improve their ability to detect and identify mycobacterium TB. The training was conducted by CDC, BD, and other training partners. The course, entitled "TB Culture and Identification," was held at the African...

Unique Collaboration Between TB Alliance and Tibotec To Accelerate Tuberculosis Drug Development

...-third of the world's population is infected with mycobacterium tuberculosis ( M.tb ), the bacillus that causes T...ro studies show that it is highly active against mycobacterium tuberculosis ( M.tb) . TMC207 has a unique mechan...iarylquinoline Drug Active on the ATP Synthase of mycobacterium tuberculosis Science 14 January 2005: Vol. 307....

Cepheid Announces European Release of Improved Test for BCR-ABL Chromosomal Translocation Associated With Chronic Myelogenous Leukemia (CML)

...key benefit in monitoring minimal residual disease," said John Bishop, Cepheid's Chief Executive Officer. "Similar to our recently announced test for mycobacterium tuberculosis , Xpert BCR-ABL Monitor uses nested PCR, a critical amplification process possible only within a fully closed integrated molecular sample...

CEL-SCI Expands Testing of Its Vaccine to Determine Efficacy Against More Virulent Strain of H1N1 Swine and Other Influenza Viruses

...or Microbiology in Philadelphia, PA. This data demonstrates that vaccines utilizing its L.E.A.P.S. vaccine technology with specificity for particular mycobacterium tuberculosis (TB) antigens can elicit immune responses that would be protective against tuberculosis and have the potential to treat swine and other ...

TREK to Introduce New In Vitro Diagnostic and Research-Use-Only Susceptibility Products at American Society for Microbiology General Meeting, Booth 1301

...VersaTREK is the only system that performs four tests on one automated platform: culture for blood, sterile body fluids, and mycobacteria, as well as mycobacterium tuberculosis (TB) susceptibility testing. The 109th annual ASM General Meeting will be held May 17-21, 2009, at the Pennsylvania Convention Cent...

US releases updated clinical guidelines for HIV-associated opportunistic infections

...formation on the prevention and treatment of hepatitis B and C infections Information on interferon-gamma release assays for the detection of latent mycobacterium tuberculosis infection Updated information on interactions between antiretroviral drugs and drugs used to treat opportunistic infections A new se...

Statement From Sequella Founder and CEO, Dr. Carol Nacy at the 'Stop TB' Meeting in Brazil on the Eve of World TB Day

...ows activity against drug sensitive and multi-drug resistant (MDR and XDR) mycobacterium tuberculosis , the causative agent of TB. SQ109 is due to begin a Phase 1B ... diseases. Orally bioavailable with excellent single-drug activity against mycobacterium tuberculosis in vitro and in vivo , SQ609 has demonstrated synergistic ...

New discovery gives tuberculosis vaccine a shot in the arm

...losis. The researchers speculate that type I interferon may give the current vaccine the "boost" necessary to elicit a protective immunity against the mycobacterium tuberculosis. "The results from our work on the novel role of type I interferons should open new perspectives in their use as a vaccine adjuvant," ...
Mycobacterium in Medical Technology

Cepheid Announces European Release of First On-Demand Molecular Test for Simultaneous Detection of Mycobacterium tuberculosis (TB) and Resistance to Rifampicin

Unique GeneXpert(R) System Capabilities Enable Powerful New TB Diagnostic Tool SUNNYVALE, Calif., April 27 /PRNewswire-FirstCall/ -- Cepheid (Nasdaq: CPHD ) today announced the release of Xpert(R) MTB/RIF as a CE IVD Mark product under the European Directive on In Vitro Diagnostic Medical...

Cepheid Receives Grant to Develop Ten-Color Real-Time PCR Detection Technology for Use in the GeneXpert(R) System

...w assay for multidrug-resistant (MDR) and extensively drug-resistant (XDR) mycobacterium tuberculosis (MTB). Future GeneXpert-based tests, which apply the ten-colo...tect with a single test will enable us to develop an assay for MDR and XDR mycobacterium tuberculosis that will give clinicians a full panel of information, includ...

CEL SCI Collaborators Demonstrate Novel L.E.A.P.S. Vaccines Immunize Mice Against Tuberculosis Antigens and Suggest Potential to Treat Swine and Other Influenzas

...monstrates that vaccines utilizing its L.E.A.P.S.(TM) (Ligand Epitope Antigen Presentation System) vaccine technology with specificity for particular mycobacterium tuberculosis (TB) antigens can elicit immune responses that would be protective against tuberculosis and have the potential to treat swine and other ...

Sequella Lead Drug Compound SQ109 Selected for Phase 1B Clinical Trial Program

...ast Track designation and FDA/EMEA Orphan Drug Designation in 2007. SQ109 shows activity against drug sensitive and multi-drug resistant (MDR and XDR) mycobacterium tuberculosis, the causative agent of TB. The Phase 1B study will assess safety and pharmacokinetics of multiple doses of SQ109 in healthy subjects. ...

Parasites That Live Inside Cells Use Loophole to Thwart Immune System

...de team studied the arginase-inducing activity of the microorganisms that cause tuberculosis and toxoplasmosis, as well as a relative of tuberculosis, mycobacterium bovis, that is used as a live vaccine. Studies in macrophages in the culture dish and in mice demonstrated that these microbes did trigger arginase ...

Nutra Pharma Announces Publication of Research on Treatment for Multiple Sclerosis

...research and development of diagnostic test kits designed to be used for the rapid identification of infectious diseases such as Tuberculosis (TB) and mycobacterium avium-intracellulare (MAI). Nutra Pharma continues to identify and acquire intellectual property and companies in the biotechnology arena. http://ww...

FDA approves MyocondaR IND for MAP in Crohn's Disease

...velopment of MyocondaR to treat patients with Crohn's Disease infected with mycobacterium avium spp paratuberculosis (MAP). The Company understands that its lead ...s aim to treat symptoms rather than the cause of the disease. The bacterium mycobacterium avium ss. paratuberculosis (MAP) is the lead candidate as an infectious cau...
Mycobacterium in Medical Products

A.F.B. Stain Control Slides

Description:... Each slide contains an A.F.B. positive staining control of mycobacterium scrofulaceum ATCC ® 19981 in simulated sputum and an A.F.B. negative staining control of Escherichia coli ATCC ® 25922 in simulated sputum....
Company:Alpha-Tec Systems
Mycobacterium in Medical Dictionary

Tuberculosis

... often deadly infectious disease caused by mycobacteria, in humans mainly mycobacterium tuberculosis . Tuberculosis usually attacks the lungs but can also af..... Tuberculosis , or TB, is an airborne infectious disease caused by mycobacterium tuberculosis . ... Pulmonary tuberculosis is usually classified based on...

Tuberculin

... Tuberculin is the name given to extracts of mycobacterium tuberculosis, M. bovis, or M. avium that is used in skin testing in anima...ulin skin test is done to see if you have ever had tuberculosis (TB) ( mycobacterium ... A tuberculin skin test is done to see if you have ever had tub...

Swimming pool granuloma

... A swimming pool granuloma occurs when water containing mycobacterium marinum ... Swimming pool granulomas can usually be treated completel...iopsy ... A swimming pool granuloma occurs when water containing mycobacterium marinum ... Swimming pool granulomas can usually be treated completel...

Scrofula

... in adults is most often caused by the bacteria mycobacterium tuberculosis. ... Scrofula can occur in children... in adults is most often caused by the bacteria mycobacterium ... Scrofula - All Information, Scrofula i... in adults is most often caused by the bacteria mycobacterium tuberculosis. ... Scrofula can occur in children...

Pulmonary tuberculosis

... Tuberculosis is a common and often deadly infectious disease caused by mycobacteria, in humans mainly mycobacterium tuberculosis . Tuberculosis usually attacks the lungs but can also affect the central nervous system, the... TB; Tuberculosis - pulmonary...

Ocular

...Ocular steroids are indicated in inflammatory conditions of the palpebral and ... The term " ocular tuberculosis" encompasses any infection by mycobacterium ... The definition of primary ocular tuberculosis (TB) has varied: some authors have ... Buy Edge III ProActive 3 Pack by OSI/ Ocular Scien...

Leprosy

... is a chronic disease caused by the bacteria mycobacterium leprae and mycobacterium lepromatosis. Leprosy is primarily a granulomato...tious disease of humans caused by the bacteria mycobacterium leprae. ... justification for isolating persons wi...

BCG

...ette-Guérin is a vaccine against tuberculosis that is prepared from a strain of the attenuated (weakened) live bovine tuberculosis bacillus, mycobacterium bovis, that has lost its virulence in humans by being... The Boston Consulting Group ( BCG ) is a global management consulting firm, founded by Br...

Acid-fast stain

...bercle bacilli with carbol acid - fast stain ( ′asəd ′ fast ′stān ) ( microbiology ) A differential stain used in identifying species of mycobacterium and one species of Nocardia Acid Fast Stain . Purpose: The acid - fast stain is a differential stain which ... (Note: Acid - fast sta...
Mycobacterium in Biological News

Experimental TB drug effective against resistant and latent mycobacterium tuberculosis

An experimental tuberculosis drug may be effective against not only multi drug-resistant forms of the disease but could also be the first compound to treat the latent stage of infection as well. Researchers report their results today at the 2006 ASM Biodefense Research Meeting. "The class of wh...

How does Mycobacterium tuberculosis infect the lung?

Tuberculosis (TB) is the most common major infectious disease today. It is estimated that two billion people--or one-third of the world's population--are chronically infected without active symptoms. Nine million new cases of active disease are diagnosed annually, resulting in two million deaths. T...

Harvard scientists solve mystery about why HIV patients are more susceptible to TB infection

... A team of Harvard scientists has taken an important first step toward the development of new treatments to help people with HIV battle mycobacterium tuberculosis (TB) infection. In their report, appearing in the July 2009 print issue of the Journal of Leukocyte Biology ( http://www.jleukbio.org ...

Powe Award supports research on how enzymes enable the pathogenicity of 2 human disease organisms

... an investment in promising achievements in an important area. The award to Sobrado will support his research on the mechanism of iron acquisition by mycobacterium tuberculosis and Aspergillus fumigatus . Iron is essential for all life. M. tubercuolis and A. fumigatus need iron in order to replicate. The...

American Chemical Society's Weekly PressPac -- May 20, 2009

...Yadav and colleagues note that a bacterium called mycobacterium immunogenum ( M. immunogenum ) was first identifi...Functional Evaluation of the Secretome Fraction of mycobacterium immunogenum, a Newly Recognized Species of the mycobacterium chelonae ...

TB -- hiding in plain sight

... Stockholm, Sweden and Addis Ababa, Ethiopia Current research suggests that mycobacterium tuberculosis can evade the immune response. The related report by Rahman et al, "Compartmentalization of immune responses in human tuberculosis: few C...

Alzheimer's, asthma, cancer, malaria and TB focus of new Singapore grants

...berculosis and malaria, which cause deaths as well as serious illness despite widespread efforts to prevent their transmission. In their studies of mycobacterium tuberculosis (MTB), which infects an estimated two billion people worldwide, National Cancer Centre of Singapore (NCCS) scientists will sift through a...

Open access research celebrated

...were introduced: Editor of the Year - Chris Arme, Parasites & Vectors Case Report of the Year Derek Rajakumar, University of Saskatchewan mycobacterium tuberculosis monoarthritis in a child Rajakumar D, Rosenberg AM Pediatric Rheumatology 2008, 6:15 (18 September 2008) http://www.ped-rheum.com...

Pitt-led researchers create quick, simple fluorescent detector for TB

...ert Einstein College of Medicine have developed an onsite method to quickly diagnose tuberculosis (TB) and expose the deadly drug-resistant strains of mycobacterium tuberculosis that can mingle undetected with treatable strains. The researchers engineered bacteriophagestiny viruses that attack bacteriato inject TB...

Einstein and Pitt researchers develop new TB test that will dramatically cut diagnosis time

...ells. In this case, the GFP gene accompanies the DNA of the phage into the mycobacterium tuberculosis cell, the bacterium that causes TB, causing the cell to glow....es for Rapid, Specific, and Sensitive Antibiotic Susceptibility Testing of mycobacterium tuberculosis ," will appear in the March 19, 2009 edition of PLoS ONE . ...
Mycobacterium in Biological Technology

Cepheid Announces New Diagnostic Technology to Aid World Efforts in Halting the Spread of Mycobacterium Tuberculosis (TB)

SUNNYVALE, Calif. March 24 /PRNewswire-FirstCall/ -- Cepheid (Nasdaq: CPHD ) today announced details of technology expected to revolutionize the speed of diagnosis of Mycobacterium tuberculosis (TB) and the resistance to common drug treatment for the disease. The new test techn...

Bacteria pack their own demise

...intestinal residents, Escherichia coli bacteria, more commonly known as E.coli, have such a T-A system in five different locations in their DNA, while mycobacterium tuberculosis bacteria even have them in 60 locations. A difficult feat The T-A mechanism has been known for a while, but nobody clearly understo...

Transave Enters Into Cooperative Research Agreement With NIH To Study ARIKACE(TM) In Nontuberculous Mycobacteria

...s have been assessed for this disease in many years. "Patients with mycobacterium avium complex or mycobacterium abscessus lung disease have limited options, which is why we welcome the o...

Magellan Diagnostic Businesses to Feature Automated Systems and Diagnostic Tests at Clinical Lab Expo

...robial-detection system performs four tests on one automated platform: culture for blood, sterile body fluids, and mycobacteria detection, as well as mycobacterium tuberculosis (TB) susceptibility testing. With a proven "tough-bug" advantage and reduced time to detection, Trek designed the VersaTREK system to imp...

CEL-SCI Files Patent Application to Support Company's Treatment for More Virulent Strain of H1N1 Swine and Other Influenza Viruses

...crobiology in Philadelphia, PA. This TB data demonstrated that vaccines utilizing the L.E.A.P.S. vaccine technology with specificity for particular mycobacterium tuberculosis (TB) antigens can elicit immune responses that would be expected to be protective against tuberculosis and have the potential to treat s...

Cepheid Announces Symposium Speakers and Program Highlights for 19th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID)

... Test for mycobacterium tuberculosis (TB) Expected to Highlight Broad On-D... expect to showcase our Xpert(R) MTB/RIF test for mycobacterium tuberculosis - a product that, in my opinion, is ... Diagnostic test for the simultaneous detection of mycobacterium tuberculosis and resistance to rifampicin ...

Sequella Receives SBIR Funding Grant from the NIH for Further Development of Tuberculosis Drug SQ609

...000 new molecular entities with activity for a broad spectrum of infectious diseases. Orally bioavailable with excellent single-drug activity against mycobacterium tuberculosis in vitro and in vivo , SQ609 has demonstrated synergistic activity with several front-line antitubercular drugs and can be readily sy...

Infectious Disease Research Institute Receives Grant for Acquisition of Core Research Equipment from M.J. Murdock Charitable Trust

... left untreated. -- Tuberculosis is a worldwide health problem. Caused by mycobacterium tuberculosis infection, every fifteen seconds someone in the developing...of Congo, Madagascar, Mozambique, Nepal, and Tanzania. It is caused by mycobacterium leprae infection. -- Chagas disease, caused by Typanosoma cruzi infection,...

BoVir(R) Named Best New Veterinary Diagnostics Product in International Animal Pharm Awards

...n demands. Its worldwide diagnostics distribution also includes BSE screening, and ParaTub(R), an automated, high throughput test for the detection of mycobacterium paratuberculosis (Johne's disease), an incurable cattle infection impacting the beef and dairy cattle industry. For more information on the annual An...

Examples of Electro-Transfected Eukaryotic and Prokaryotic Cells

... Leuconostoc (3 species) Listeria (5 species) mycobacterium (3 species) Pediococcus acidilactici Propionibacteriu... Acholeplasma laidlawii Methylophillus (3 species) mycobacterium (4 species) Serpula hyodysenteriae Spiroplasma citri ...

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Mycobacterium in Biological Products

Rabbit Anti-MYCOBACTERIUM TUBERCULOSIS Polyclonal Antibody, Unconjugated from AbD Serotec

Description:... ANTI mycobacterium TUBERCULOSIS...
Company:AbD Serotec
Mycobacterium in Biological Definition

Antibiotic resistance

...esistance to penicillin substitutes is also known beyond S. aureus . By 1993 Escherichia coli was resistant to five fluoroquinolone variants. mycobacterium tuberculosis is commonly resistant to isoniazid and rifampin and sometimes universally resistant to the common treatments. Other pathogens showi...

Immune system

...host. With the adjuvant, the response is much more robust. Historically, a commonly used formula Freund's Complete Adjuvant , an emulsion of oil and mycobacterium . It was later discovered that toll-like receptors, expressed on innate immune cells, are critical in the activation of adaptive immunity. Disord...

Microbiology

... generation times (the time needed for division of a bacterial cell in two in optimal conditions; ~30 minutes for E. coli , but 12 to 24 hours for mycobacterium tuberculosis ) Cells can easily survive in isolation from other cells Unicellular eukaryotes reproduce by mitotic division and prokaryotes ...

Antibiotic resistance

...esistance to penicillin substitutes is also known beyond S. aureus . By 1993 Escherichia coli was resistant to five fluoroquinolone variants. mycobacterium tuberculosis is commonly resistant to isoniazid and rifampin and sometimes universally resistant to the common treatments. Other pathogens showi...

Robert Koch

...(named after J.R. Petri ), both of which are still used today. With these techniques, he was able to discover the bacterium causing tuberculosis ( mycobacterium tuberculosis ) in 1882 (he announced the discovery on March 24 ). Tuberculosis was the cause of one in seven deaths in the mid-19th century. The...
Mycobacterium in Biological Dictionary

VNTR

..., analysis and reviews from Psychology Journals, Newspapers, and magazines at HighBeam.com. Free Trial, Credit Card Required. ... analysis tool for mycobacterium tuberculosis MIRU- VNTR (MLVA)-, Spoligo-, RD (LSP)-, and SNP-data. ... Change VNTR loci set. 24 loci. Change VNTR loci order ... Defini...

Tandem repeat sequence

...esting, ... Sequence Information (annotated) Variant Allele Reports. Tri-Allelic Patterns ... Use of Short Tandem Repeat Sequences to Study mycobacterium leprae in Leprosy ... Such variability makes short tandem repeat sequences unsuitable as a general ... ...

Tandem repeat sequences

... (1999) Tandem repeats finder: a program to analyze DNA sequences . Nucleic Acids Res. ... Use of Short Tandem Repeat Sequences to Study mycobacterium leprae in Leprosy ... Such variability makes short tandem repeat sequences unsuitable as a general ... ...

Polymorphic loci

...ghly polymorphic DNA loci from Human Biology provided by Find Articles at BNET Multiple Polymorphic Loci for Molecular Typing of Strains of mycobacterium leprae ... we have identified nine additional polymorphic loci in a small set of four ... Polymers of random short oligonucleotides detect pol...

Ocular

.... Ocular ultrasonography is a relatively new application in emergency medicine. ... The term " ocular tuberculosis" encompasses any infection by mycobacterium ... The definition of primary ocular tuberculosis (TB) has varied: some authors have ... Ocular albinism is characterized by severely impaire...

Bacilli

...ing diode fluorescence microscopy to detect acid-fast bacilli ... Impact of antibiotic resistance in gram-negative bacilli on empirical and... mycobacterium tuberculosis or unidentified acid fast bacilli (presumed to be M. ... tuberculosis, the multiplication of the bacilli within the lungs of such ....
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