Novel technology detects human DNA mutations
Researchers at today reported unprecedented benefits in the company's technology for the medical analysis of human DNA. genotyping...Fox Chase Cancer Center scientists identify immune-system mutation
A team of Fox Chase Cancer Center scientists led by immunologist Dietmar J. Kappes, Ph.D., has identified the genetic mutation that keeps a mouse strain from developing white blood cells, or lymphocytes, called helper T cells. The report by Kappes and his colleagues appears in the Feb. 24 issue of Nature. Kappes' laboratory first discovered the mice with this naturally occurring defect in...Mitochondrial DNA mutations play significant role in prostate cancer
Mutations in mitochondrial DNA (mtDNA) playan important role in the development of prostate cancer, according toresearch by scientists at Emory University School of Medicine and theUniversity of California, Irvine. The findings are published onlinethis week in the Proceedings of the National Academy of Sciences(PNAS). Mitochondrial DNA, which is separate from nuclear DNA, is foundin the hun...Same mutation aided evolution in many fish species, Stanford study finds
After decades of laboratory work studying how animals evolve, researchers sometimes need to put on the hip waders, pull out the fishing net and go learn how their theory compares to the real world. According to a Stanford University School of Medicine study published in the March 25 issue of Science, Mother Nature is more predictable than lab experiments suggest. In a diverse group of fish...Bioelectronic ‘signatures?hold key to DNA mutations
A new method to identify DNA mutations may shepherd in an era of small, portable, electronic devices for the rapid screening and identification of genes that harbor disease. Joseph Wang, director of the Center for Bioelectronics and Biosensors at the Biodesign Institute at ASU, led a team effort that successfully merged work in the fields of biosensors, electronics, and nanotechnology to...Random DNA mutagenesis Service from Yorkshire Bioscience Ltd
Description:We can introduce random mutations to the gene supplied by a customer. Mutated DNA will be then cloned into a vector of choice to obtain a library of the mutated DNA. Mutation frequency can be set to a desired value within 1-20 mutations per kb. Number of clones 106-108. Mutations can be restricted to a desired region of a gene. 106-108 clones...MutaGEL Parodontitis from Alpco Diagnostics
Description:...MutaPLATE Salmonella sp. from Alpco Diagnostics
Description:Screening test for the detection of Salmonella sp. by means of DNA amplification, subsequent molecular hybridization and detection on a microtitre plate....MutaPLATE Listeria monocytogenes from Alpco Diagnostics
Description:Screening assay to detect the Listeria monocytogenes in food samples byDNA amplification and molecular hybridization on a microtiter plate....A Positive Selection Assay for Mutation Analysis in Big Blue Animals
Select-cII mutation assay kit Animals Stratagene Stratagene now offers an alternative way to perform mutational analysis inthe Big Blue<sup...Big Blue Rodent Cell Cultures for Mutagenesis Studies
Rat and mouse embryonic cell lines are useful for in vitro mutagenesisstudies Stratagene Cloning Systems, Inc. The Big Blue rat cell line and the Big Blue transgenic mouse embryoniccell line are useful for in vitro mutagenesis studies. These cell lines are partof the Big Blue transgenic rodent mutagenesis assay system...High-Efficiency Site-Directed Mutagenesis of Large Plasmid Vectors
QuikChange XL: a highly versatile kit for site-directed mutagenesis oflarge plasmids Michael Borns Peter Vaillancourt Holly Hogrefe Jeff Braman Stratagene The QuikChange site-directed mutagenesis kit* characteristicallygenerates mutagenesis efficiencies exceeding 80%. We have created a new kit formutagenesis of large plasmid...Organize Your Data from the Big Blue Mutation Assay
Stratagene Solana Consulting Group, Solana Beach, CA Stratagene introduces the MutaTrak electronic notebook to record BigBlue transgenic rode...Fluorescence-Based Single-Tube Assays to Rapidly Detect Human Gene Mutations
Xiuyuan Hu Beti Belachew Lingyu Chen HaoqiangHuang Jason Zhang Stratagene can distinguish human DNA specimens that differ by a few nucleotides or only asingle nucl...CCR5 Mutation Confers Immunity Against HIV But Not Against West Nile Virus Illness
A research conducted by Philip M. Murphy, M.D., and colleagues say that mutation in CCR5 (cell surface protein) protects people against HIV infection but increases the risk of developing West Nile virus (WNV) illness. // West Nile virus (WNV) illness is caused due to a mosquito-borne virus. This research as conducted at the National Institute of Allergy and Infectious Diseases (NIAID)...Mutation connected to Osteoporosis
Researchers report they have identified a genetic defect that causes a rare bone disease in which the body makes too much bone, a finding that may lead to treatments for osteoporosis. According to Dr. Michael Levyn, director of the bone and mineral center at Hopkins University, the new finding will help bone researchers understand why the body loses the ability to make new bone cells as p...Mutating viruses helps produce antibodies
Scientists at the University of California reported that, a rapidly mutating gene in a virus that preys on bacteria may help lead to a new way to create artificial antibodies. This surprising mechanism may even be found in humans and other life, suggesting a new way of generating biological diversity.// Jeff Miller, author of this study, the viruses are a treasure trove of fascinating b...Achondroplasia Mutation, Fetal
Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...APC Resistance Mutation Detection
Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...Apolipoprotein B Mutation Detection
Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...ANA380 Exhibits Activity In Vitro Against Multiple Clinically Relevant Hepatitis B Virus Mutants
Poster Presentation at EASL on April 13, 2007, 2007 SAN DIEGO, and SEOUL, South Korea, April 13/PRNewswire-FirstCall/ -- Anadys Pharmaceuticals, Inc. and LG LifeSciences, Ltd., presented data from an in vitro study showing thatANA380 (LB80380) retains potency against multiple mutant strains ofhepatitis B virus (HBV) which are resistant to lamivudine,adefovir, entecavir or telbivudine, dur...