Novel Asthma Study Shows Multiple Genetic Input Required; Single-gene Solution Shot Down
For patients with high-risk breast cancer treated with radical mastectomy and adjuvant chemotherapy, the addition of radiation therapy leads to better survival outcomes with few long-term toxic effects, according to a 20-year follow-up of a randomized trial, which appears in the January 19 issue of the Journal of the National Cancer Institute. The British Columbia randomized radiation the...Multiple Campylobacter Genomes Sequenced
In 1995, the first complete bacterial genome sequence was published. Now, nearly 200 bacterial genomes have been completed, and a new one hits the scientific press most weeks. This burgeoning industry is not just scientific “stamp collecting,?however. Having all these genome sequences may provide useful clues about why some bacteria cause human disease, how to control their spread, and how to tre...Gene Signatures Predict Interferon Response For Multiple Sclerosis Patients
Multiple sclerosis (MS) can be an unpredictable disease. It develops when the body's immune system attacks healthy nerve cells and disrupts normal nerve signaling. Patients experience a wide range of symptoms—including tingling, paralysis, pain, fatigue, and blurred vision—that can appear independently or in combination, sporadically or persistently. Although symptoms appear in no particular orde...Multiple-drug resistant gene expression pattern predicts treatment outcome for pediatric leukemia
A new study is providing scientists with a better understanding of why some pediatric acute lymphoblastic leukemia (ALL) patients fail to respond to treatment even when existing clinical predictive criteria point towards a positive treatment outcome. The research, published in the April issue of Cancer Cell, is likely to facilitate development of new strategies to combat drug resistance and treat...Higher risk for cervical cancer seen among women infected with multiple HPV types
Although doctors have known that the cervical tissue at the opening to the womb can harbor multiple HPV types, this study is the first to document that the risk for developing cervical cancer, the second most common form of cancer in women worldwide, is higher in females infected with multiple HPV types than those infected with just one HPV type. In addition, the study's findings provide...FAST Frame Multiple Slide Plate from Whatman, Inc
Description:High Throughput Processing of Microarrays Using the New FAST(tm) Frame Multi-Slide Plate! FAST Frame multiple slide plate is designed to hold four, 16-pad FAST Slides and the corresponding multi-well incubation chambers in a microplate footprint for high throughput processing of microarrays. The footprint dimensions meet the standards recommended by the Society of Biomolecular Screening.<U...Multiple Affinity Removal System from Agilent Technologies
Description:Now, for the first time, you can identify and characterize high-value, low-abundant proteins faster and more efficiently without interferences. The Agilent Multiple Affinity Removal System allows you to remove unwanted, multiple high-abundant proteins from human serum, plasma, CSF samples and more with just one device. Remove six targeted, high-...Multiple Species Tissue Array - Lung Tissue from ProSci, Inc
Description:The Multiple Species Tissue Array (MSTA) slides were designed to study protein expression patterns in different cells and tissues from multiple species. Tissue slices from three different species are mounted on each MSTA slide which can then be treated as a single histological slide for H&E staining, immunohistochemistry, or hybridization. This format allows a rapid analysis of p...Multiple Species Tissue Array - Testis Tissue from ProSci, Inc
Description:The Multiple Species Tissue Array (MSTA) slides were designed to study protein expression patterns in different cells and tissues from multiple species. Tissue slices from three different species are mounted on each MSTA slide which can then be treated as a single histological slide for H&E staining, immunohistochemistry, or hybridization. This format allows a rapid analysis of p...Multiple Species Tissue Array - Breast Tissue from ProSci, Inc
Description:The Multiple Species Tissue Array (MSTA) slides were designed to study protein expression patterns in different cells and tissues from multiple species. Tissue slices from three different species are mounted on each MSTA slide which can then be treated as a single histological slide for H&E staining, immunohistochemistry, or hybridization. This format allows a rapid analysis of p...Mx4000 Multiplex Quantitative PCR System*,PPP
Stratagene has improved upon currently available QPCR machines with the Mx4000 multiplex quantitative PCR system. This new system offers better performance and functionality at a more economical price. Real-time quantitative PCR (QPCR) allows researchers to quickly and easilyquantify nuclei...Fully automated DNA purification and efficient multiplex PCR for analysis of microsatellite loci
Marion Schmidt, Holger Engel, Markus Sprenger-Hauels, Corinna Kppers, Gaby Schulte, Silke Zobel, and Dirk Lffert QIAGEN GmbH, Hilden, Germany Microsatellites highly polymorphic DNA markers comprised of nucleotides that are repeated in tandem arrays and distributed throughout the geno...Naked DNA Vaccination May Conquer Arthritis and Multiple Sclerosis
A novel modification of a new technology born of genetic engineering, and known as naked DNA vaccination, holds the potential of overcoming autoimmune diseases such as multiple sclerosis and rheumatoid arthritis. The vaccine is currently being successfully tested in animals. In multiple sclerosis (MS) and rheumatoid arthritis (RA), the body essentially attacks itself, caus...Multiple organ disease cured by genes
Researchers University of Pennsylvania report the first ever use of gene therapy, in dogs, to cure a gene involving multiple body organs.// Mucopolysaccharidosis VII (MPS) is one of a group of rare genetic disorders called lysosomal storage diseases. Other examples include Tay Sachs disease and Gaucher disease. MPS involves an enzyme defect, leading to blindness, heart disease, and loss of mobili...Associated therapy for multiple myeloma
According to a new study it is observed that thalidomide is effective as first-line therapy for newly diagnosed multiple myeloma patients when combined with a standard chemotherapy agent. Researchers from the Mayo Clinic in Rochester, Minn.// gave 60 newly diagnosed myeloma patients the drug thalidomide along with the synthetic steroid dexamethasone. Results show 55 percent of patients responded...Latest drug shows promise in multiple myeloma
According to researchers, many trials show that a new type of drug can assist patients with multiple myeloma who have failed to respond to other treatments.// Multiple myeloma is an incurable cancer of the bone marrow. Researchers at Dana-Farber Cancer Institute have been assessing a new drug, called bortezomib, in a group of 180 patients who had not been helped by other forms of treatment. In th...Acclaim 7000 Multiple Application Laser
Description:The Acclaim 7000 Nd:YAG laser allows you to expand your practice by offering cosmetic procedures such as hair removal, treatment of leg and facial veins, our Dermique LaserFACIAL for sun-damaged skin. The Acclaim 7000 offers selectable parameters for customizing treatment based on skin and hair type, improving outcomes on a variety of patients....LIGACLIP ERCA Endoscopic Rotating Multiple Clip Applier
Description:Ethicon Endo-Surgery provides clip appliers in 10mm and 5mm sizes. Our market-leading 10mm endoscopic clip appliers provide precise clip placement. The LIGACLIP ERCA Endoscopic Rotating Multiple Clip Applier is a sterile, single patient use instrument designed to provide a means of ligation through ENDOPATH Surgical Trocars. The instrument delivers 20 titanium clips that individually adv...ACUCLIP Right-Angle (Multiple Clip Applier With Titanium Clips)
Description:ACUCLIP Endoscopic Right-Angle Multiple Clip Applier, 10 mm Shaft Diameter with 20, 8 mm Titanium Clips...ENDO CLIP MultApplier (Multiple Use Clip Applier)
Description:The Auto Suture ENDO CLIP MultApplier reusable clip applier is designed for use with the ENDO CLIP MultApplier single-use loading unit, each of which contains eight (8) titanium clips. The overall length of the shaft of the instrument is approximately 12.8" (32.5 cm). The clip applier is designed for introduction and use through an appropriately sized Auto Suture trocar sleeve or lar...Gentium's Defibrotide Seen as Active in Multiple Myeloma
NEW YORK--(BUSINESS WIRE)--Jun 27, 2007 - Gentium S.p.A. (Nasdaq:GENT) announced the presentation of both clinical and preclinicaldata that support the safety, activity, synergy and potentialmechanism of action of Defibrotide in combination with anticancertherapy in multiple myeloma. Investigators presented both an updatefrom the Company's ongoing Phase I/II clinical trial for patientswith...ACE-011 Improves Multiple Myeloma Bone Disease in a Preclinical Model
KOS, Greece--(BUSINESS WIRE)--Jun 26, 2007 - Acceleron Pharma,Inc., a biopharmaceutical company developing therapeutics for thetreatment of musculoskeletal, metabolic and cancer-relateddiseases, today announced results demonstrating that ACE-011, anovel anabolic bone agent for the treatment of bone loss, preservedbone mass and architecture in a murine model of multiple myeloma.Multiple myel...