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The development of a CXCR2 chemokine receptorbinding assay using the LEADseeker Multimodality Imaging System

CXCR2 • GPCR • receptor binding assay • LEADseeker • SPA Imaging Beads Chemo-attractant cytokines (chemokines) are low molecular weight, pro-inflammatory cytokines with potent leukocyte activation and/or chemotactic activity (1). Chemokines are classified into four families (CXC, CC, C, and CX...

Performance of the AMARA HitHunter Chemiluminescence Kinase Assay with the LEADseeker Multimodality Imaging System

AMARA • kinase assay • LEADseeker • chemiluminescence It is predicted that at least 500 kinase and phosphatase enzymes exist, their activities having wide-ranging regulatory responses. Many kinases are part of a signaling cascade in disease pathways such as inflammation and cancer, so identifying modulators of kinase...

The development of a melanocortin MC4 receptor binding assay using the LEADseeker Multimodality Imaging System

Melanocortin • receptor binding assay • LEADseeker • SPA Imaging Beads Pro-melanocortins are present in high levels in the pituitary and are processed into three major peptide hormone fragments: adrenocorticotrophin (ACTH), the melanocyte stimulating hormones, and β-endorphin. The various melanocyte stimulat...

The development of a melanocortin MC5 receptor binding assay using the LEADseeker Multimodality Imaging System

Melanocortin • receptor binding assay • LEADseeker • SPA Imaging Beads Pro-melanocortins are present in high levels in the pituitary and are processed into three major peptide hormone fragments: adrenocorticotrophin (ACTH), the melanocyte stimulating hormones, and β-endorphin. The various melanocyte stimulat...

The development of a calcitonin-gene related peptide (CGRP) receptor-binding assay using the LEADseeker Multimodality Imaging System

CGRP • receptor binding assay •LEADseeker • SPA Imaging Beads Calcitonin-gene related peptide (CGRP) is believed to have an important physiological role in the central nervous and cardiovascular systems. Indeed, using CGRP receptors isolated from coronary and basilar arteries, studies have i...

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(Date:10/3/2008)...- Inc. Magazine recently included,Connolly Consult...ing,private companies in the country. The list is ...segment of the economy -- America,s,independent-mi...ies,represent the backbone of the U.S. economy., ...03/NY36880LOGO ), Connolly Consulting,s consiste...
(Date:10/3/2008)... Discrimination; Recognizes,Importance of Mental H.../PRNewswire-USNewswire/ -- Mental Health,America t...approval of a,mental health parity legislation tha...ion against Americans with mental health and subst...lans., The legislation, which recognizes the impo...
(Date:10/3/2008)...search Foundation(R) Collection of, Bouquets to T...Research, LOS ANGELES, Oct. 3 /PRNewswire/ -- Tel...g only hand-arranged, hand-delivered floral,arrang...nth-long,collaboration with The City of Hope, John... Cancer Center in southern California and national...
(Date:10/3/2008)...- As the population ages, a big,question employers...e the,financial crunch of an illness?", In most c...eck to,paycheck and now need two incomes to provid... spouses becomes critically ill and unable to work...ut the healthy,employee/spouse is strained by the ...
Breaking Medicine News(10 mins):Health News:Connolly Consulting Makes the 2008 Inc. Magazine's List of America's 5000 Fastest Growing Companies 2Health News:Mental Health America Hails Approval of Federal Parity Legislation 2Health News:Mental Health America Hails Approval of Federal Parity Legislation 3Health News:Teleflora and Nationally Recognized Hospitals to Honor Women Battling Breast Cancer 2Health News:Teleflora and Nationally Recognized Hospitals to Honor Women Battling Breast Cancer 3Health News:Can Your Employees Survive the Financial Crunch of an Illness? 2
(Date:10/3/2008)... Aluminum toxicity, a global agricultural problem,...ricultural productivity for more than half of the ...s have puzzled over how toxic levels of aluminum d...is that aluminum binds to several targets in the r...and ultimately interrupting plant growth. , Now,...
(Date:10/3/2008)...e has confirmed the appointment of Esin Gulari, de...emson University, to serve on the National Science...ulari for the post along with six other distinguis...r me as a scientist and an engineer," said Gulari....ke contributions on a national level. I hope that ...
(Date:10/3/2008)... 3, 2008 Case Western Reserve University School o... to participate in The National Children,s Study, ...study on the interaction of genes and the environm...y, NIH officials named Case Western Reserve Univer...ing study centers which would recruit study volunt...
(Date:10/3/2008)...ing with the observance of Nuclear Medicine Week (...ess Month (October), SNM released today a new fact...ar imaging technologies that are dramatically impr... and treated. , Molecular imaging is a highly ef...sing and treating breast cancer. Physicians report...
Breaking Biology News(10 mins):UC Riverside biochemists devise method for bypassing aluminum toxicity effects in plants 2UC Riverside biochemists devise method for bypassing aluminum toxicity effects in plants 3US Senate confirms Clemson University engineering Dean Esin Gulari to National Science Board 2NIH selects Case Western Reserve University to participate in National Children's Study 2SNM releases new fact sheet on breast cancer and molecular imaging 2Senior GE Executive to lead IMRIS Sales team in the U S 20659 1Landauer Inc Declares Regular Cash Dividend 20656 1Preschoolers in Family Child Care Homes Need More Activity 20653 1Preschoolers in Family Child Care Homes Need More Activity 20653 2Vion Pharmaceuticals to Present Clinical Data on Cloretazine 28R 29 28VNP40101M 29 at the ASCO 28R 29 Annual Meeting 2240 1Vion Pharmaceuticals to Present Clinical Data on Cloretazine 28R 29 28VNP40101M 29 at the ASCO 28R 29 Annual Meeting 2240 2Vion Pharmaceuticals to Present Clinical Data on Cloretazine 28R 29 28VNP40101M 29 at the ASCO 28R 29 Annual Meeting 2240 3
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