How is H pylori adhesion to gastric cells associated with MUC1 mucin VNTR size?
The Gram negative bacterium H pylori is involved in the pathogenesis of several gastrointestinal diseases, ultimately leading to gastric carcinoma. Adhesion of the bacteria to the gastric mucosa is an essential step for colonization and infection.
It is therefore important to know factors that ...
A better mesh: Researchers 'tighten' body's protective coating
...or the INBT.
The team showed that tiny strands in the mucus layer -- the mucin
fibers -- naturally tend to bundle and bunch together, creating gaps large ...gent to the mix, Lai and his colleagues partially disrupted the bundling of mucin
fibers, a procedure that decreased the size of the holes in the mesh. Parti...
Targeted Anticancer Drugs - In Vitro Assessment and Non-Invasive Imaging of Patient and Tumor Status Will Determine Clinical and Commercial Success
...EK); matrix metalloproteinase-2 (MMP-2); MMP-9;
melanin; mesothelin (CAK1); methionine aminopeptidase 2 (MetAP2);
motility-related protein-1 (MRP- 1); mucin
1 (MUC1); murine double minute 2
(MDM2), HDM2; N-acetylated alpha- linked acidic dipeptidase (NAALADase);
N-cadherin (NCAD); neural precursor cell exp...
JCI online early table of contents: Jan. 2, 2008
...uggested that TIM-1specific antibody therapy might provide a new approach to preventing transplant rejection.
TITLE: The emerging role of T cell Ig mucin
1 in alloimmune responses in an experimental mouse transplant model
Mohamed H. Sayegh
Brigham and Womens Hospital, and Children...
Cure For Persistent Oral Fungal Problem May Be Possible
...to treat potential oral infections up to double their original power.
One peptide called MUC7 12-mer, which occurs naturally in the human salivary mucin
molecule is quite effective for treating oral fungal infections. Even active in very low concentrations, when used with inhibitors, the peptide killed...
Mucin in Medical Technology
Mucin in Medical Dictionary
...ult to anastomose with nasal mucosa . ... fibrous adhesions between the lacrimal sac mucosa and the head of the stent may ... ... different mucin
genes in the ileal mucosa of patients with Crohn's disease and controls. ... healthy and involved ileal mucosa suggests a primary or very .....
Mucin in Biological News
SinuNase Phase 3 show almost 100 percent of chronic sinusitis cases are from fungal-induced inflamma
...ges in the sinuses. At the time of enrollment, all patients have had nasal mucin
collected. Subsequently, these specimens are being tested for eosinophilic...atient's nose and tests for eMBP, which is uniquely detectable in the nasal mucin
of patients with CS.
Smoking turns on genes -- permanently
... smoking: reversible (TFF3, encoding a structural component of mucus; CABYR, in it's newly discovered bronchial role), partially reversible (MUC5AC, a mucin
gene) and irreversible (GSK3B, involved in COX2 regulation). These findings were tested against a second cohort of current, former and non-smokers.
Progress toward an antitumor vaccine
...od is based on an immunocompatible connection by way of a sulfur atom, namely, a thioether.
Epithelial tumor cells have unusually large amounts of mucin
MUC1 on their surface. This MUC1, in comparison with its “normal” cousins, is also modified in a very characteristic manner. Mucins are mucilaginous s...
Mucin in Biological Technology
Drug Reduces Airway Mucus in Preclinical Asthma Model
...American Journal of Respiratory Cell and
Molecular Biology 2008; 38: 256-262, entitled, "Chronic Exposure to
Beta-Blockers Attenuates Inflammation and mucin
Content in a Murine Asthma
Model," airway mucus hypersecretion and inflammation were almost completely
reversed upon treatment with certain beta block...