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Morphine in Medical News

FDA Reverses Stance on Removal of Morphine Painkiller

Appeals from hospice experts mean an unapproved drug, one of 14 given recent warning, will remain on the market, agency says,,,, THURSDAY, April 9 (HealthDay News) -- Bowing to the pleas of hospice experts, the U.S. Food and Drug Administration has backed off its intent to remove from ...

GSU study first to confirm long-term benefits of morphine treatment in infants

ATLANTA A recent study conducted by researchers at Georgia State University is the first of its kind to demonstrate that administration of preemptive morphine prior to a painful procedure in infancy blocks the long-term negative consequences of pain in adult rodents. These studies have serious i...

Roxane Laboratories, Inc. Announces the Approval of Morphine Sulfate Tablets and Oral Solution

COLUMBUS, Ohio, July 14 /PRNewswire/ -- Roxane Laboratories, Inc. announced today the approval of its New Drug Application (NDA) for Morphine Sulfate Tablets and Oral Solution CII by the U.S. Food and Drug Administration. Roxane Laboratories' Morphine Sulfate CII is available in 15mg, 30mg tab...

ETHEX Corporation Voluntarily Recalls a Single Lot of Morphine Sulfate 60 mg Extended Release Tablets Due to the Potential for Oversized Tablets

ST. LOUIS, June 9 /PRNewswire/ -- ETHEX Corporation announced today that it has voluntarily recalled a single lot of morphine sulfate 60 mg extended release tablets (Lot No. 91762) due to a report of a tablet with twice the appropriate thickness. Oversized tablets may contain as much as two ti...

Blocking Potent Oxidant Could Prevent Morphine Tolerance

Findings in animal tests may lead to new therapies for treating chronic pain FRIDAY, Nov. 2 (HealthDay News) -- Blocking a substance called peroxynitrite, a potent oxidant that's formed when patients take morphine, can prevent the development of tolerance to the pain-relieving effects of the na...

KV Pharmaceutical Announces FDA Approval for Morphine ER 100 mg and 200 mg Tablets

Approval of Two Additional Strengths Gives ETHEX Full Line of Morphine ER Tablet Capability ST. LOUIS, Oct. 25 /PRNewswire-FirstCall/ -- KV Pharmaceutical Company (NYSE: KVa/KVb) announced today that it has received approval from the U.S. Food and Drug Administration (...

How Morphine Affects Memory

The brains ability to retain memory takes a beating with morphine, a study has shown. Researchers from Brown University feel// that this discovery could have implications in the development of addiction therapy. To understand the effects of morphine on the brain, researchers demonstrated the...

Using Morphine to Hasten Death Is a Myth, Says Doctor

Using morphine to end a person’s life is a myth, argues a senior doctor in a letter to this// week’s BMJ. It follows the case of Kelly Taylor, a terminally ill woman who went to court earlier this month for the right to be sedated into unconsciousness by morphine, even though it will hasten h...

Inhibition of morphine tolerance by spinal melanocortin receptor blockade

Recent research suggests that the melanocortin system is an important component influencing the changes in the spinal neuronal plasticity observed after chronic morphine administration//. The chronic use of morphine is accompanied by the development of morphine tolerance, which is one of the maj...

Medicines Top Source of Kids' Poisonings

...good or getting high, experimentation and then pain relief. Students used drugs such as hydrocodone, oxycodone (Oxycontin), hydromorphone, meperidine, morphine and codeine without a prescription, the researchers found. The dangers of misused cold medications for infants and young children has also been a t...
Morphine in Medical Technology

King Pharmaceuticals Showcases Data From Pain Pipeline of Medicines Designed to Deter Common Methods of Non-Therapeutic Use

...tain pellets of an extended-release formulation of morphine sulfate surrounding an inner core of naltrexone hy... drawn to measure plasma concentrations (concs) of morphine (M) naltrexone (N) and its metabolite, 6-beta-nalt... ALO-01 was taken as directed, steady state plasma morphine levels remain stable. Naltrexone and 6-beta-N do n...

Methadone Frequently Causes Menopausal Symptoms in Young Women

...ng methadone failed to inform them of hormonal suppression risks caused by methadone. Physicians prescribing methadone, Vicodin, Oxycontin, Percocet, morphine and other opiate pain medications, seldom test or treat patients for hormonal deficiencies caused by these medications. Although studies reveal m...

QRxPharma Successfully Completes Comparative Study for Dual-Opioid(TM) Pain Therapy

...te MoxDuo(TM) IR Provides Better Tolerability Than morphine and Oxycodone Alone SYDNEY, Australia and BED...rofile of MoxDuo(TM) IR against component doses of morphine and oxycodone. Results demonstrated that MoxDuo(T...; further, when compared to equianalgesic doses of morphine and oxycodone, MoxDuo(TM) IR produced fewer and le...

DURECT Reports Positive Phase IIb Data from TRANSDU(TM)-Sufentanil Clinical Program

... As a result of converting screened patients to stable pain control and into the maintenance period (see above), the conversion ratios from oral morphine equivalents at baseline to TRANSDUR-Sufentanil dosage strengths were established and are expected to be utilized in the Phase III program. Ef...

Nektar Announces Positive Results from Phase 2 Study of Oral NKTR-118 in Patients with Opioid-Induced Constipation (OIC)

... in SBMs at the end of the first week of randomized study drug. Patients in the study were being treated for moderate to severe pain with 30 to 1,000 morphine equivalent units. Under the study protocol, patients were randomly assigned to placebo or one of three different dose cohorts (5 mg, 25 mg, and 50 mg...

Archimedes Pharma Announces Successful Proof-of-Concept Results on Two Intranasal Development Projects

...ted products include Gliadel, a biodegradable wafer impregnated with an anti-cancer drug, carmustine, for high-grade glioma; Zomorph and Oramorph both morphine products for pain; and Pabrinex, a high potency vitamin formulation used to treat the symptoms of malnutrition especially in patients with acute alcoh...

Innocoll Announces Dosing of Last Patient in US Phase 2 Clinical Trial to Investigate CollaRx(R) BUPIVACAINE SURGICAL IMPLANT for the Management of Post-Operative Pain

...of sustained, post-operative analgesia for approximately 96 hours as measured by VAS (visual analogue scale) scores and reduced dependence on systemic morphine administered by PCA (patient-controlled analgesia). This extended analgesic action was achieved despite a low total bupivacaine dose (150mg as the hyd...

Headache Specialists Convene in Boston For 50th Annual American Headache Society Meeting

...ch outnumber neurons 20:1, have been shown to prompt chronic pain in a variety of ways, such as by a virus, nerve damage or even medication. morphine and other opiates also activate glial cells, which mean those drugs you're taking to alleviate pain might actually be making it worse. -- ...

QRxPharma Releases Additional Phase 3 Data for Q8003IR 'Dual Opioid' Pain Therapy

...l Phase 3 data for Q8003IR establishing a 12mg/8mg morphine and oxycodone combination as the preferred dose fo...nfirm that our patented dual opioid combination of morphine and oxycodone provides synergistic effects on pain...d outcomes compared to what is typically seen with morphine or oxycodone. The significance of these observatio...

New AMITIZA 8 mcg Phase III Studies Demonstrated Overall Symptom Improvement in Adult Women with Irritable Bowel Syndrome with Constipation (IBS-C)

... 12pm-2pm PDT 844 Lubiprostone Reverses the Inhibitory Oral; Tuesday, May Action of morphine on Mucosal 20, 2008 from 4pm- Secretion in the Human Jejunum 5:30pm PDT; ...
Morphine in Medical Products

SureStep Morphine (MOP)

Description: For the qualitative detection of single and multiple drugs and drug metabolites in human urine...
Company:Inverness Medical Professional Diagnostics

Opiates - Rapid Test

Description:...phy based one step in vitro test. It is designed for qualitative determination of Opiates and its metabolite in human urine specimens. The presence of morphine in human urine above a cut-off level of 300 ng/mL can be detected. This assay has not been evaluated in the point of care location and is for use by H...
Company:Bio-Quant, Inc.

Opiates II - Rapid Test

Description:...phy based one step in vitro test. It is designed for qualitative determination of Opiates and its metabolite in human urine specimens. The presence of morphine in human urine above a cut-off level of 2,000ng/mL can be detected. This assay has not been evaluated in the point of care location and is for use by ...
Company:Bio-Quant, Inc.

SureStep Drug Screen Tests - One-Step Immunoassays (THC)

Description:... both MDA and MDEA but no cross-reactivity to any isomer of methamphetamine or amphetamine.The SureStep Drug Screen Tests for cocaine, amphetamine and morphine are available in SAMHSA recommended cutoffs or in high-sensitivity formats for zero-tolerance testing....
Company:Wampole Laboratories

SureStep Drug Screen Tests - One-Step Immunoassays

Description:...both MDA and MDEA but no cross-reactivity to any isomer of methamphetamine or amphetamine. The SureStep Drug Screen Tests for cocaine, amphetamine and morphine are available in SAMHSA recommended cutoffs or in high-sensitivity formats for zero-tolerance testing....
Company:Wampole Laboratories

SureStep™ Drug Screen Tests - One-Step Immunoassays (Amphetamine)

Description:...DA and MDEA but no cross-reactivity to any isomer of methamphetamine or amphetamine.The SureStep™ Drug Screen Tests for cocaine, amphetamine and morphine are available in SAMHSA recommended cutoffs or in high-sensitivity formats for zero-tolerance testing....
Company:Wampole Laboratories

SureStep™ Drug Screen Tests - One-Step Immunoassays (Methamphetamine)

Description:...DA and MDEA but no cross-reactivity to any isomer of methamphetamine or amphetamine.The SureStep™ Drug Screen Tests for cocaine, amphetamine and morphine are available in SAMHSA recommended cutoffs or in high-sensitivity formats for zero-tolerance testing....
Company:Wampole Laboratories

SureStep™ Drug Screen Tests - One-Step Immunoassays (THC)

Description:...DA and MDEA but no cross-reactivity to any isomer of methamphetamine or amphetamine.The SureStep™ Drug Screen Tests for cocaine, amphetamine and morphine are available in SAMHSA recommended cutoffs or in high-sensitivity formats for zero-tolerance testing....
Company:Wampole Laboratories

SureStep™ Drug Screen Tests - One-Step Immunoassays (Cocaine II)

Description:...DA and MDEA but no cross-reactivity to any isomer of methamphetamine or amphetamine.The SureStep™ Drug Screen Tests for cocaine, amphetamine and morphine are available in SAMHSA recommended cutoffs or in high-sensitivity formats for zero-tolerance testing....
Company:Wampole Laboratories

SureStep™ Drug Screen Tests - One-Step Immunoassays (Cocaine)

Description:...DA and MDEA but no cross-reactivity to any isomer of methamphetamine or amphetamine.The SureStep™ Drug Screen Tests for cocaine, amphetamine and morphine are available in SAMHSA recommended cutoffs or in high-sensitivity formats for zero-tolerance testing....
Company:Wampole Laboratories

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Morphine in Biological News

A link is found between morphine addiction and the tendency to explore

A team of researchers from the UAB has found experimental evidence in rats showing a link between addiction to morphine and the tendency to explore perseveringly. This is the first time a direct relationship has been found without other psychological characteristics, such as anxiousness, that might...

Hepatitis C complicated by morphine withdrawal

Researchers at the University of Pennsylvania have demonstrated that morphine withdrawal complicates hepatitis C by suppressing IFN-alpha-mediated immunity and enhancing virus replication. The paper by Wang et al., Morphine withdrawal enhances hepatitis C virus (HCV) replicon expression, appears in...

Fish may actually feel pain and react to it much like humans

...line. The researchers believed that those with the morphine would be able to withstand higher temperatures bef...iting different behaviors. "The fish given the morphine acted like they always had: swimming and being fis... aversive experience." Garner believes that the morphine blocked the experience of pain, but not behavioral...

Study first to pinpoint why analgesic drugs may be less potent in females than in males

...n; however, it is becoming increasingly clear that morphine is significantly less potent in women compared wit...pulation of mu-opioid receptor expressing neurons. morphine and similar drugs bind to these mu-opioid receptor...ales. This higher level of receptors is what makes morphine more potent in males because less drug is required...

Discovering drugs, biofuels in tropical seas

...Named the Harvard Foundation's 2007 Scientist of the Year, his work led to development of Ziconotide, a commercial drug considered more effective than morphine in blocking out extreme pain. Shipworms, the marine equivalent of termites and the scourge of wooden structures in estuarine and marine habitats wor...

Codeine not safe for all breastfeeding moms and their babies

...ic death of an infant who died from an overdose of morphine acquired from breast milk, Koren and his team, loc...eine at a rapid rate, producing significantly more morphine in their system than most of the population. While...can end up exposing their babies to high levels of morphine through their breast milk. This can cause babies t...

Caltech engineers build mini drug-producing biofactories in yeast

...cals, materials, and products. However, the natural plant sources of BIAs accumulate only a small number of the molecules, usually "end products" like morphine and codeine that, while valuable, can't be turned into other compounds, thus limiting the availability of useful new products. To their reticuline-...

Incense is psychoactive: Scientists identify the biology behind the ceremony

...ed to incensole acetate, the compound had no effect on their brains. Perhaps Marx wasnt too wrong when he called religion the opium of the people: morphine comes from poppies, cannabinoids from marijuana, and LSD from mushrooms; each of these has been used in one or another religious ceremony. said Gerald...

A research of the UGR shows the genetic predisposition to develop alcohol abuse

... that the lack of endorphin is hereditary, and thus that there is a genetic predisposition to become addicted to alcohol. Beta-endorphin is a kind of morphine released by the brain in response to several situations, such as pain. In this way, beta-endorphins can be considered endogenous analgesics to numb or...

Opium and marijuana research go underground

... and thebaine, and cannabis produces psychoactive cannabinoids and is used as a source of high-quality fiber and oil. The domestic market for codeine, morphine and oxycodone, which is derived from thebaine, is in excess of $1.6 billion annually, all of which is currently imported. Canada is well-positioned to...
Morphine in Biological Technology

ETHEX Corporation Voluntarily Recalls Specific Lots of 30 mg. and 60 mg. Morphine Sulfate Extended Release Tablets Due to the Potential for Oversized Tablets

NDC #58177-320-04 & 58177-330-04 Lot Numbers listed below ST. LOUIS, June 13 /PRNewswire/ -- ETHEX Corporation announced today that it has voluntarily recalled specific additional lots of morphine sulfate 60 mg extended release tablets, and specific l...

Detection of Morphine and Morphine-Glucuronide in Saliva or Urine with a Rapid and Simple Method Without Derivatization on the Varian 500-MS

Jason S. Wood, Ph.D. Varian, Inc. Introduction Testing for drugs of abuse (DoA) is becoming more prevalent in various environments, including forensics and social justice environments as well as in sporting events. Non-heroin opiates such as morphine, oxycodone, and...

QRxPharma Initiates Comparative Phase 2 Proof-of-Concept Study for MoxDuo(TM) IV Pain Therapy

... efficacy and safety of MoxDuo(TM) IV (intravenous morphine and oxycodone) versus IV morphine alone for the treatment of moderate to severe post...M) IV has fewer opioid-related adverse events than morphine alone at equianalgesic doses and (2) whether the m...

Cumberland Pharmaceuticals Announces FDA Approval of Caldolor(TM)

...ly injectable drugs currently available to reduce pain are opioids, such as morphine and meperdine, and ketorolac, a non-steroidal anti-inflammatory drug. Opioi...intensity within the first 24 hours while also significantly reducing their morphine use. Clinical trials including critically ill and non-critically ill patien...

Phosphagenics Announces Completion of Transdermal Patch Prototypes

...rrently administered either orally or intravenously. It is more potent than morphine with fewer side effects. Worldwide sales of oxycodone exceed $US1.5 billion...in patch should allow us to deliver other opioid based compounds, including morphine and hydromorphone, as well as other products that are targeted for delivery...

QRxPharma Initiates Second Comparative Study for MoxDuo(TM) IR Dual-Opioid(TM) Pain Therapy

...ainst the present standard use of intravenous (IV) morphine in patients who self-control their pain relief usi...hat consists of two opioid drugs (a fixed ratio of morphine and oxycodone). While many analgesic combination ... indicate that QRxPharma's patented combination of morphine plus oxycodone works synergistically to increase a...

ETHEX Corporation Issues Nationwide Voluntary Recall of Products

...peridine/Promethazidne Capsules (58177-027-04) morphine InveAmp, 20mg x 1mL (58177-886-56) morphine InveAmp, 5mg/.25mL (58177-888-80) morphine Sulfate Concentrated Oral Solution 20mg/1ml (58177...

QRxPharma Initiates Comparative Study for MoxDuoIR(TM) Dual-Opioid(TM) Pain Therapy

...MoxDuoIR(TM) against equivalent analgesic doses of morphine and oxycodone alone for the treatment of acute mod...acy when compared to equivalent analgesic doses of morphine and oxycodone alone," said Dr. John Holaday, Manag...and safety to corresponding doses of oxycodone and morphine in patients experiencing moderate to severe pain f...

Abbott Scientists Present a New Approach for Treating Attention-Deficit Hyperactivity Disorder

...mpounds that may have the ability to elicit relief across a broad spectrum of pain states. The lead compounds have demonstrated efficacy comparable to morphine across a number of different pre-clinical pain models -- including osteoarthritis, post-operative and cancer pain. About Abbott Abbott is a global...

Innocoll Announces Dosing of First Patient in a Second US Phase 2 Clinical Trial to Investigate CollaRx(R) BUPIVACAINE SURGICAL IMPLANT for the Management of Post-operative Pain

...of sustained, post-operative analgesia for approximately 96 hours as measured by VAS (visual analogue scale) scores and reduced dependence on systemic morphine administered by PCA (patient- controlled analgesia). This extended action was achieved despite a low total bupivacaine dose (150mg as the hydrochlorid...
Morphine in Biological Definition

Biodiversity

...tory. For example, quinine comes from cinchona tree (used to treat malaria ), digitalis from the foxglove plant (chronic heart trouble), and morphine from the poppy plant (pain relief). According the National Cancer Institute , over 70 % of the promising anti-cancer drugs come from plants in the...

Drug

...or their euphoric effects Opiates refined from the opium poppy morphine Codeine Synthetic and semi-synthetic opioids Heroin Ox... Amphetamines Anabolic steroids Inhalants Methadone morphine Varies from tolerated to prohibited for medical use: Cannabis ...

Peptide

...ns such as gluten , casein , egg protein and spinach protein are broken down, opioid peptides are formed. These peptides mimick the effects of morphine , and those who are unable to break them down will experience mental illness. These peptides are quite short and are given names such as casomorphine...

Peptide

...ns such as gluten , casein , egg protein and spinach protein are broken down, opioid peptides are formed. These peptides mimick the effects of morphine , and those who are unable to break them down will experience mental illness. These peptides are quite short and are given names such as casomorphine...
Morphine in Biological Dictionary

RNAi

...encing by RNA interference ( RNAi ) literature and resources using selected links or top search and clustering engines. ... RNAi turns poppies off morphine ... RNA interference ( RNAi ) is a mechanism in molecular biology where the presence ... RNAi is distinct from other gene silencing phenome...
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