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Monocyte in Medical News

Expansion of monocyte subset could serve as a biomarker for HIV progressions

An increase in the CD163+/CD16+ monocyte subset could be a biomarker for the progression of HIV disease, according to researchers at Temple University. The researchers reported their findings, CD163/CD16 Coexpression by Circulating Monocytes/Macrophages in HIV: Potential Biomarkers for HIV Infec...

UCLA scientists identify how immune cells may help predict Alzheimer's risk

...etry, researchers then measured the amount of amyloid beta ingested by the immune cells by assessing how much fluorescence was being emitted from each monocyte cell. The 18 Alzheimer's disease patients in the study showed the least uptake of amyloid beta; the healthy control group, which consisted of 14 u...

Study in Nature Medicine establishes major new treatment target in diseased arteries

...normal mice, with the opposite being true for mice with extra CypA. Angiotensin II treatment also dramatically increased expression of cytokines (e.g. monocyte chemoattractant protein 1(MCP-1)), unless CypA was missing. "Our lab has been studying CypA since the early 1990s," Berk said. "We had to deter...

Ophthalmology highlights Jan. 2009

...and 8 diabetic patients without retinopathy. Vascular endothelial growth factor (VEGF), intercellular adhesion molecule (ICAM)-1, interleukin (IL)-6, monocyte chemotactic protein (MCP)-1 and the anti-inflammatory pigment epithelium-derived factor (PEDF) were selected because earlier research had linked them ...

Researchers identify how binge drinking may drive heart disease

... buildup. At this point, adhesion molecules on the monocyte surfaces unfold and grab onto key proteins on the ..., like anchors that snag the vessel wall. Once the monocyte swings close to the wall on its tether, it can the...e current study found that acetaldehyde stimulated monocyte adhesion through its effect on three important pro...

Chemical liberated by leaky gut may allow HIV to infect the brain, Einstein scientists find

...ions of monocytesHIV/GFP-producing monocytes from the HIV/GFP-TG mice, and monocytes from the GFP-TG mice producing GFP aloneand injected each type of monocyte into control mice. Four days later, the researchers examined the brains of the injected mice to see whether monocytes from the bloodstream had cro...

Biomarker May Signal HIV Progression

... researchers found an increase in the CD163+/CD16+ monocyte subset may coincide with the advancement of human ...w, all we know is what the correlations are." A monocyte is a specific white blood cell, a part of the huma...ents with detectable virus had an increase of this monocyte subset that correlated with the amount of virus th...

An emerging candidate for protecting patients from liver injury after abdomen surgery

...leukocyte and the activity of hepatic enzymes, including LDH, ALT, and AST, and the concentration of pro-inflammatory mediators such as TNF-, IL-6 and monocyte chemotactic protein-1 (MCP-1). After careful evaluation, the researchers concluded R1 prevents I/R-induced hepatic microcirculation disturbance and he...

Evidence links anemia drugs with leukemic transformation in patients with primary myelofibrosis

...formation were documented. Other factors appeared to contribute to the development of leukemia, including anemia, leukocytosis and peripheral blood monocyte count greater than or equal to 1x109/L (both are measures of elevated white blood cells), hypercatabolic symptoms (results of excess metabolism), a sp...

IDM Pharma Announces Data Presentation From Mifamurtide (L-MTP-PE) Compassionate Use Program

...m2 IV over 1 hour) was administered twice a week for 12 weeks followed by once a week for 24 weeks in combination with aerosol recombinant granulocyte monocyte colony stimulating factor (GM-CSF), an immune stimulating agent. In addition, some patients in the program were also treated with gemcitabine (n=2) or...
Monocyte in Medical Technology

Opexa Advances Monocyte Derived Islet Technology to Proof of Principle in stz-induced NOD/SCID Mice

THE WOODLANDS, Texas--(BUSINESS WIRE)--Jun 27, 2007 - Opexa Therapeutics, Inc. (NASDAQ:OPXA), a company involved in the development and commercialization of cell therapies, presented poster presentations at the 5th International Society for Stem Cell Research Annual Meeting (ISSCR) in Cairns, Queen...

VisEn Molecular Imaging Technology Enables Key Insights Into Newly Discovered Biologic Pathway Published in SCIENCE

...s. The newly reported biologic pathway relates to monocyte deployment from the spleen to inflammatory sites, ...plenic reservoir of monocytes, and demonstrate the monocyte deployment to inflammatory sites in vivo . In th...f the heart to identify and quantify biomarkers of monocyte activity in vivo . These results enabled an impo...

CEL SCI Collaborators Demonstrate Novel L.E.A.P.S. Vaccines Immunize Mice Against Tuberculosis Antigens and Suggest Potential to Treat Swine and Other Influenzas

...ges of Medicine and Pharmacy and colleagues showed that CEL-SCI's L.E.A.P.S. vaccines can activate and cause human immature dendritic cells from blood monocyte cells to become dendritic cells that secrete the IL-12 cytokine. The dendritic cells that result initiate a protective cell mediated and antibody imm...

Alba Therapeutics Presents New Data for Larazotide Acetate at the 2008 American College of Gastroenterology Annual Scientific Meeting

...t increase in the anti-tTG titer in the placebo (control) group, which was prevented in the group on larazotide acetate. -- Other trends in specific monocyte populations induced by gluten challenge were also prevented to varying extents by larazotide acetate. The second presentation, "Larazotide Acetate, ...

IDM Pharma Announces Updated Data From Mifamurtide (L-MTP-PE) Compassionate Access Program

...d by once a week for 24 weeks. In addition, some patients in the program were also treated with other agents including aerosol recombinant granulocyte monocyte colony stimulating factor (GM-CSF) an immune stimulating agent (n=20), ifosfamide (n=4), and/or gemcitabine (n=2). Results to date are as follows:...

Opexa Therapeutics Reports Positive Top-line Data in Phase I/II Dose Escalation Trial with Tovaxin for Multiple Sclerosis

...usive worldwide license for adult multipotent stem cells derived from mononuclear cells of peripheral blood. The technology allows large quantities of monocyte derived stem cells to be produced efficiently for use in autologous therapy, thus circumventing the threat of rejection. The Company is in preclinical...

Opexa Presents Tovaxin Research at Federation of Clinical Immunology Societies Annual Meeting

...usive worldwide license for adult multipotent stem cells derived from mononuclear cells of peripheral blood. The technology allows large quantities of monocyte derived stem cells to be produced efficiently for use in autologous therapy, thus circumventing the threat of rejection. The Company is in preclinical...

Opexa Therapeutics Reports Positive Top-line Data in Phase I/II Extension Trial with Tovaxin for Multiple Sclerosis

...usive worldwide license for adult multipotent stem cells derived from mononuclear cells of peripheral blood. The technology allows large quantities of monocyte derived stem cells to be produced efficiently for use in autologous therapy, thus circumventing the threat of rejection. The Company is in preclinical...
Monocyte in Medical Products

Giemsa Stain

Description:...and bone marrow. Erythrocytes stain pink to buff with platelets exhibiting a very light, pale pink. Leukocyte nuclear chromatin stains magenta-purple, monocyte cytoplasm stains the classical "ground glass" blue and lymphocyte cytoplasm stains clear, sky blue....
Company:Richard-Allan Scientific
Monocyte in Medical Dictionary

Monocyte

Monocyte is a type of white blood cell, part of the human body's immune system. ... Retrieved from "http://en.wikipedia.org /wiki/ Monocyte " ... monocyte ( ) n. A large, circulating, phagocytic white blood cell, having a single well-defined nucleus and very fine...

Erythrocyte

...id bilayer and the cytoskeleton.3 ... The cytoskeleton is the other domain of the erythrocyte membrane. ... The B-cell antigen CD22 mediates monocyte and erythrocyte adhesion. Stamenkovic I, Seed B. ... Like CD2, the T-cell erythrocyte receptor, CD22 may facilitate antigen ... Erythrocyt...
Monocyte in Biological News

Melanoma vaccine strategy shows promise in laboratory experiments

... T cells to attack the melanoma cells. Another type of immune cell called a monocyte was used to present the peptide, BRAFV600E, to the killer T cells to trigge...00E peptide would trigger the killer T cells even more effectively than the monocyte cells used in the current study. Indeed, such prepared dendritic cells migh...

Source of crucial immune cell in the skin discovered

...nt beads in mice in a group of immune cells known as monocytes. They then followed the cells to observe their fate. They found that a specific type of monocyte know as Gr-1 homes to inflamed skin, proliferates, and then differentiates to form Langerhans cells. They also found that a protein, called colony sti...
Monocyte in Biological Technology

CEL-SCI Files Patent Application to Support Company's Treatment for More Virulent Strain of H1N1 Swine and Other Influenza Viruses

...edicine and Pharmacy and colleagues at the 12th NFID meeting in Baltimore showed that CEL-SCI's L.E.A.P.S. vaccines can activate and cause human blood monocyte cells to become dendritic cells that secrete the IL-12 cytokine. The dendritic cells that result initiate a protective cell mediated and antibody imm...

CEL-SCI Presents Data at Prestigious Medical Conference Demonstrating That Its L.E.A.P.S. Technology Stimulates Maturation of Human Blood Cells Into Dendritic Cells Suggesting Potential for Prevention and Treatment of Infectious Disease

...astern Ohio Universities Colleges of Medicine and Pharmacy and colleagues showed that CEL-SCI's L.E.A.P.S. vaccines can activate and cause human blood monocyte cells to become dendritic cells that secrete the IL-12 cytokine. The dendritic cells that result initiate a protective cell mediated and antibody imm...

MedImmune Presents Data Highlighting its Progressive Inflammatory Disease Portfolio at the 72nd Annual Meeting of the American College of Rheumatology

...ehouse, M.Sc., Sunday, October 26 from 9:00 a.m. - 11:00 a.m. in Hall A, Abstract: 46 -- Internalization of the antibody (CAM-3001) following monocyte cell surface binding to the GM-CSFR alpha chain - Brandon Higgs, Ph.D., Sunday, October 26 from 9:00 a.m. - 11:00 a.m. in Hall A, Abstract: ...

Cellix Ltd. Launches VenaEC Biochip for Flow-based Cell-adhesion Assays

...essfully on the VenaEC Biochip. Validated examples to date include a Human Coronary Artery Endothelial Cell (HCAEC) monolayer for the investigation of monocyte adhesion for cardiovascular diseases and a Human Microvascular Endothelial Cell (HMVEC) monolayer for the investigation of eosinophil adhesion for res...

Laser Capture Microdissection (LCM) for the Analysis of Macrophage Gene Expression from Atherosclerotic Lesions

...ene transcript levels of the following genes were measured: vascular cell adhesion molecule-1 (VCAM-1), intercellular adhesion molecule1 (ICAM-1), and monocyte chemoattractant1(MCP-1) (see Table I for gene primer sequences). As shown in Table II, LPS stimulation increased the expression of the Nuclear Factor-...

HL-60

...5.028 11/1999 Cell line HL-60, human monocyte like cells (suspension cell line) Transfection with Plasmid pEGFP-N1 (in bidistilled H 2 O) ...

Eppendorf Multiporator Transfection Protocols for Eukaryotic Cells

... line 721.82: EBV transfected B-cell line HeLa: Cervix epitheloid carcinoma HL-60: monocyte like cells Jurkat: T-cell line T98G: Glioblastoma t-HUVEC: Transformed ...

Eppendorf Multiporator Transfection Protocols for Eukaryotic Cells

... line 721.82: EBV transfected B-cell line HeLa: Cervix epitheloid carcinoma HL-60: monocyte like cells Jurkat: T-cell line T98G: Glioblastoma t-HUVEC: Transformed ...

Enzyme Immunoassay for Studying Intracellular Levels of cAMP

...e maximal stimulation in the cell line of interest. In addition to Jurkat cells, AC toxin has also been shown to elevate cAMP in monocyte macrophages, 10 polymorphonuclear leukocytes and alveolar macrophages, 11 natural killer cells 12 and HL-60 promyelocytic leu...
Monocyte in Biological Products

UCB Monocyte Cell Chip-IHC from 3H Biomedical AB

Description: Umbilical cord blood CD14+ Monocytes, For immunohistochemistry (IHC) Cell Chip with Human Umbilical Cord Blood Monocytes, B Cells and NK Cells...
Company:3H Biomedical AB

Canine CCL2 (JE; MCP-1) ELISA development Kit, DuoSet from R&D Systems

Description:...s DuoSet ELISA Development kit contains the basic components required for the development of sandwich ELISAs to measure natural and recombinant canine monocyte Chemotactic Protein 1 (MCP-1) in cell culture supernates and serum.1 Each kit contains sufficient materials to run ELISAs on approximately fifteen 96-...
Company:R&D Systems

Mouse Anti-Human DEP-1 / CD148 Monoclonal Antibody, Fluorescein Conjugated, Clone 143-41 from R&D Systems

Description:... Human DEP-1/CD148 Fluorescein MAb (Clone 143-41) Protein Family: Granulocyte Markers, monocyte Markers, Phosphatases & Regulators, Other Dendritic Cell Molecules...
Company:R&D Systems
Monocyte in Biological Dictionary

Monocytes

... monocyte is a type of white blood cell, part of the human body's immune system. Monocytes have two main functions in the immune system: (1) replenish r...

Beta sheet

...yclopedia ... Dr Chromo's School: the beta -pleated sheet ... Home of protein beta - sheet tools ... The featured beta - sheet is from the monocyte chemoattractant protein 1 (MCP-1) (PDB code 1DOK) ... ... beta - sheet tools ... These beta - sheets can be encoded in graphs, where vertic...
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