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Molar in Medical News

Celator(R) Pharmaceuticals Initiates Research Agreement With Cephalon, Inc.

...fective therapies to treat cancer. CombiPlex(R), the company's proprietary drug ratio technology platform, represents a novel approach that identifies molar ratios of drugs that will deliver a synergistic benefit, and locks the desired ratio in a nano-scale drug delivery vehicle that maintains the ratio in...

Celator(R) Pharmaceuticals to Present at 2009 BIO International Convention

...fective therapies to treat cancer. CombiPlex(R), the company's proprietary drug ratio technology platform, represents a novel approach that identifies molar ratios of drugs that will deliver a synergistic benefit, and locks the desired ratio in a nano-scale drug delivery vehicle that maintains the ratio in...

Celator(R) Pharmaceuticals Presents New Data on CPX-351 And CPX-1 at the American Association for Cancer Research

...r highlight the utility of maintaining synergistic molar ratios of chemotherapeutic agents through nano-sca...tform, represents a novel approach that identifies molar ratios of drugs that will deliver a synergistic be... liposome formulation containing a synergistic 5:1 molar ratio of cytarabine (Cyt) and daunorubicin (Daun),...

Celator(R) Pharmaceuticals to Present at Future Leaders in the Biotech Industry Conference

...fective therapies to treat cancer. CombiPlex(R), the company's proprietary drug ratio technology platform, represents a novel approach that identifies molar ratios of drugs that will deliver a synergistic benefit, and locks the desired ratio in a nano-scale drug delivery vehicle that maintains the ratio in...

KODAK 9000 3D Extraoral Imaging System Earns High Marks From Dental Professionals In Third Party Survey

... system: “With the KODAK 9000 3D System, you know where an implant needs to be placed, and you also know precisely where the nerve and third molar are,” said Joey de Graffenried, DDS, of Kilgore, Texas. “The 2D panoramic images are the crispest I've seen and the 3D CBCT images are als...

Celator(R) Pharmaceuticals Enrolls First Patient in Its Phase 2 Study of CPX-351 in Acute Myeloid Leukemia in First Relapse

...PX-351 CPX-351 represents a new approach to treatment, where synergistic molar ratios of combined drugs are encapsulated in a drug delivery vehicle in ord...drug ratio technology platform, represents a novel approach that identifies molar ratios of drugs that will deliver a synergistic benefit, and locks the desi...

Children's Museum of Phoenix & Delta Dental of Arizona Foundation Celebrate National Children's Dental Health Month

... Special Appearances Planned by molar Man! Glendale, AZ (Vocu... throughout February. Dr. Gary Johnson a.k.a. molar Man will make the first of eight appearances at th... Spanish, will be distributed to show attendees by molar Man during these appearances. The Children's M...

United Concordia Celebrates National Children's Dental Health Month

...ealth Month by encouraging children to visit the new Becky Brush and Matty molar section on the company's Web site. "Dental health education is crucia... Klich, United Concordia's National Dental director. "Becky Brush and Matty molar help make dental health education fun for children of all ages, whether a c...

Celator(R) Pharmaceuticals To Present at Biotech Showcase 2009

...and more effective therapies to treat cancer. CombiPlex(R), the company's drug ratio technology platform, represents a novel approach that identifies molar ratios of drugs that will deliver a synergistic benefit, locks the desired ratio in a drug delivery vehicle that maintains the ratio in patients with ...

Celator(R) Pharmaceuticals Presents Phase 1 Results With CPX-351 in Patients With Advanced Leukemia at the American Society of Hematology Meeting

...oach to developing drug combinations in which drug molar ratios with synergistic anti-tumor activity are en...tform, represents a novel approach that identifies molar ratios of drugs that will deliver a synergistic be... carrier (CPX-351) containing a synergistic, fixed molar ratio of cytarabine (Ara-C) and daunorubicin (DNR)...
Molar in Medical Technology

Scientists Discover Why Teeth Form in a Single Row

...any teeth, mice lacking both Msx1 and Osr2 grew the first molars, but no additional teeth. Thus, without Osr2, enough BMP4 was expressed for the first molar teeth to grow, but without Msx1, the BMP4 signal was not amplified to the point where it could kick off the next tooth in the row. With these results,...

The Leukemia & Lymphoma Society and Celator Pharmaceuticals Announce Partnership to Accelerate Development of CPX-351 for AML

...represents a new approach to developing combinations of drugs in which drug molar ratios with synergistic anti-tumor activity are encapsulated in a drug deli...drug ratio technology platform, represents a novel approach that identifies molar ratios of drugs that will deliver a synergistic benefit, locks the desired ...

Celator(R) Pharmaceuticals Announces Enrollment of First Patient in Phase 2 Study with CPX-351

...s a liposomal formulation of cytarabine and daunorubicin delivered in a 5:1 molar ratio shown in preclinical studies to represent a synergistic ratio for use...se 1 Study of a Liposomal Carrier (CPX-351) Containing a Synergistic, Fixed molar Ratio of Cytarabine (Ara-C) and Daunorubicin (DNR) in Advanced Leukemias wi...

Celator Pharmaceuticals Receives Orphan Drug Designation for Anticancer Agent CPX-351

...eting in December and will report Phase 1 results at that time. CPX-351 is a liposomal formulation of cytarabine and daunorubicin delivered in a 5:1 molar ratio shown to be strongly synergistic in preclinical studies. CPX-351 was developed using Celator's proprietary CombiPlex(R) technology platform. O...

Celator(R) Pharmaceuticals Reports CPX-351 Shows Anti-Cancer Activity in Leukemia Patients

...sions and the fact that the drug has been very well-tolerated." CPX-351 is a liposomal formulation of cytarabine and daunorubicin delivered in a 5:1 molar ratio shown in preclinical studies to represent a synergistic ratio for use in combination chemotherapy. CPX-351 represents a new approach to developi...
Molar in Medical Products

IGF-II, w/ Extraction IRMA Test

Description:...evels are low in GH deficiency [7], although IGF-II levels may also decrease in GH excess and with exogenous administration of IGF-I [3]. The combined molar concentrations of IGF-I and IGF-II (i.e. Total serum IGF) is proportional to serum IGFBP-3 and consequently may be useful for evaluation of GH-related...
Company:Diagnostic Systems Laboratories, Inc.

IGF-II, w/ Extraction ELISA Test

Description:...evels are low in GH deficiency [7], although IGF-II levels may also decrease in GH excess and with exogenous administration of IGF-I [3]. The combined molar concentrations of IGF-I and IGF-II (i.e. Total serum IGF) is proportional to serum IGFBP-3 and consequently may be useful for evaluation of GH-related...
Company:Diagnostic Systems Laboratories, Inc.

IGF-II, Non-Extraction IRMA Test

Description:...evels are low in GH deficiency [7], although IGF-II levels may also decrease in GH excess and with exogenous administration of IGF-I [3]. The combined molar concentrations of IGF-I and IGF-II (i.e. Total serum IGF) is proportional to serum IGFBP-3 and consequently may be useful for evaluation of GH-related...
Company:Diagnostic Systems Laboratories, Inc.

IGF-II, Non-Extraction ELISA Test

Description:...evels are low in GH deficiency [7], although IGF-II levels may also decrease in GH excess and with exogenous administration of IGF-I [3]. The combined molar concentrations of IGF-I and IGF-II (i.e. Total serum IGF) is proportional to serum IGFBP-3 and consequently may be useful for evaluation of GH-related...
Company:Diagnostic Systems Laboratories, Inc.

IGFBP-3 IRMA Test

Description:... allowing IGFBP-3, along with ALS, to regulate the actions of the IGFs. The molar concentration of IGFBP-3 in normal serum is proportional to the molar concentration of total IGFs (i.e. IGF-I + IGF-II) [1]. In addition, total I...
Company:Diagnostic Systems Laboratories, Inc.

IGFBP-3 ELISA Test

Description:... allowing IGFBP-3, along with ALS, to regulate the actions of the IGFs. The molar concentration of IGFBP-3 in normal serum is proportional to the molar concentration of total IGFs (i.e. IGF-I + IGF-II) [1]. In addition, total I...
Company:Diagnostic Systems Laboratories, Inc.
Molar in Medical Dictionary

Pregnancy Loss

...s Remembrance Day. ... Learn more about Pregnancy Loss Remembrance Day, which is recognized in all 50 ... Blighted Ovum, Ectopic Pregnancy , molar Pregnancy , and Stillbirth ... heard they cause miscarriage, because they are not documented causes of a loss . ... Pregnancy loss can happe...

Molar pregnancy

... molar pregnancy is an abnormal form of pregnancy , c...erized by the presence of a hydatidiform mole . molar pregnancy comprises two distinct entities, par...s. Complete moles have no identifiable... A molar pregnancy is a mass of abnormal tissue (hydat...

Incisor

...r ... The relative stability of the incisor relationships in the present investigation ... incisor . Real-time Video Performance extension to molar VST. Project Home. Downloads ... (Setting up your system for Incisor ) Wiki page edited by momoDmonster ... The role of the BDJ is to inform its ...

Hyperemesis gravidarum

... that may occur during the first trimester of pregnancy include miscarriage, hyperemesis gravidarum (extreme vomiting), ectopic pregnancy, and molar ... Human chorionic gonadotropin and hyperemesis gravidarum . T. Murphy Goodwin, MD ... Transient hyperthyroidism and hyperemesis gravidar...

Hydatidiform mole

... molar pregnancy is an abnormal form of pregnancy, char...rized by the presence of a hydatidiform mole . molar pregnancy comprises two distinct entities, part...d curettage (D ... A hydatidiform mole , or molar pregnancy, results from over-production of the ......

Choriocarcinoma

... to be invasive and to metastasize early and widely through ... Choriocarcinoma . Hydatidiform mole, invasive mole, cancers of pregnancy, or molar pregnancy ... This occurs when cancer affects the tissues that would ... Verified medical information database including information on hundred...
Molar in Biological News

Scientists discover why teeth form in a single row

...any teeth, mice lacking both Msx1 and Osr2 grew the first molars, but no additional teeth. Thus, without Osr2, enough BMP4 was expressed for the first molar teeth to grow, but without Msx1, the BMP4 signal was not amplified to the point where it could kick off the next tooth in the row. With these results,...

From seed to nuts: human ancestor's face evolved to eat survival foods

...lice said. "The overall structure of the Australopith face looks well-adapted to the sort of function we tested in our paper, but this is at odds with molar microwear patterns that suggest a varied diet of relatively few hard foods. It is possible that their facial architecture was driven not by their day-...

Paracetamol, one of most used analgesics, could slow down bone growth

... In Medicine, paracetamol is used to soothe every kind of pain, from simple molar pain to pain produced by bone fractures. This medicine is one of the most used nowadays. However, research carried out at the Departamento de Enferme...

'Banana-jawed' fossil mammal linked to rare sound-producing skill

...y understood," Simons said. In order to gain answers, the Duke team measured tooth samples from the newly available fossils. "We looked first at molar teeth, which are used for grinding food, and found that all of them in our specimens were identical, so we were pretty sure they were from the same sp...

Neanderthal teeth grew no faster than comparable modern humans'

...archers that a Neanderthal childhood was equal to a modern human's. "The missing key bit of data to show that would be evidence for when the first molar tooth erupted in the Neanderthals, and we simple have no evidence of when that occurred," she said. The length of time is important, the researche...
Molar in Biological Technology

Celator(R) Pharmaceuticals Presents Data on the Activity of CPX-351 Against Leukemia at the European Hematology Association Congress

... liposomal encapsulation maintains the desired 5:1 molar ratio of cytarabine:daunorubicin in CPX-351, exten...is confirmed that CPX-351 maintained the fixed 5:1 molar ratio of cytarabine:daunorubicin for prolonged per...cells, allowing the release of the synergistic 5:1 molar ratio of the active agents intracellularly, and de...

Cephalon Submits Supplemental New Drug Application for FENTORA

...phalon subsidiary CIMA LABS. FENTORA is covered by patents until 2019. The sugar-free FENTORA tablet is placed between the cheek and gum above a rear molar tooth where it remains until it dissolves. When it comes into contact with saliva, FENTORA's delivery system generates a chemical reaction believed to...

Celator(R) Pharmaceuticals Study Shows CPX-571 Maintains Synergistic Ratio of Irinotecan and Cisplatin to Improve Anti-tumor Activity

...r's proprietary CombiPlex technology, researchers then engineered a combination of irinotecan and cisplatin in liposomes to maintain a synergistic 7:1 molar ratio following intravenous administration. The product, known as CPX-571, was compared to a combination of irinotecan and cisplatin administered as f...

Mice teeth explain the troubles with human wisdom teeth

...olars develop from front-to-back so that the first molar appears first and the posterior molars bud sequentially along the jaw. Normally the last molar to develop is the third, or wisdom tooth. Experime... numbers, one curious effect being that the second molar makes up one-third of total...

Fundamentals of Fermentation: Techniques For Benchtop Fermentors

... 3. The probe should be stored standing upright. The electrode tip should be immersed in the solution of 3 molar KC1 or a buffer solution between pH 4 and pH 7. The two rubber "T" stoppers should be inserted. At no time should the electrode be allowed t...

Separation of Peptides by Hydrophilic Interaction Chromatography Using TSKgel Amide-80

...and sequester the apparent IEX interactions. Subsequent work (not shown) indicates little improvement with the addition of equal molar amounts of TFA and TEA at 0.1% or 0.2% over what is possible with TFA alone(4). The advantage of using TFA to eliminate IEX interactions ...

Practical Aspects of Evaluation of Chromatographic Data in Size Exclusion Chromatography

...ntly the most common method for determination of molar masses and molar mass distributions of synthetic polymers. It is ... intra-laboratory repeatability (precision) of the molar mass data, often better than +/- 5%. At the same...

XANTHOCHROMIA IN CEREBROSPINAL FLUID

...es into account and compensates for the interference of haemoglobin and bilirubin absorption bands. Figure 1: molar Extinction Coefficient of Haemoglobin (left) and Bilirubin (right) [cm-1/M vs nm] The method consists in scanning the region 350-5...

Evaluation of FlashPlate in a Helicase Assay

... 1. DNA oligo #2 was 5'-labeled with 33 P by T4 polynucleotide kinase, following the manufacturer's protocol. 2. Equal molar quantities of DNA oligo #1 and the [ 33 P]-labeled #2 oligo were annealed at 90C for 5 minutes and cooled to room temperature. 3. Approxima...

Simultaneously characterizing and quantifying chloramphenicol and its metabolite using LC/MS/MS

...terials and methods Biological Methods: Chloramphenicol was incubated with rat liver S9 fractions at a substrate concentration of 50 micro molar and a protein concentration of 1 mg/ml in 100 mM potassium phosphate buffer at pH 7.4. Reactions were initiated by the addition of nicotinamide adenin...
Molar in Biological Products

Eclipse Particle sizing systems from Wyatt Technology

Description:...ts multi-angle light scattering (MALS) instruments: DAWN, miniDAWN Tristar, as well as the Optilab DSP. The combined system provides absolute size and molar mass distributions of the particles/molecules separated by the AFFF unit. The combined system solves the most difficult sizing tasks in the macromolec...
Company:Wyatt Technology

Ligase, T4 DNA from USB Corp.

Description:...ligation reaction, a combination of 2040 ng of vector DNA and a 1:3-10 fold molar excess of foreign DNA will produce an adequate yield of recombinant genomes... 1. Combine the following: Vector DNA (2040 ng) __ l Insert DNA (310-fold molar excess) __ l Ligation Buffer, 10X 5 l Water __ l T4 DNA Ligase __ l (1...
Company:USB Corp.

Mouse resistin Neutralizing Peptide from ABR-Affinity BioReagents

Description:...d mouse resistin, catalog # PA1-1050. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~ 70-fold) for competitive inhibition of antibody-protein binding reactions. Storage: -20 C, Avoid Freeze/Thaw Cycles....
Company:ABR-Affinity BioReagents

Bovine rhodopsin Neutralizing Peptide from ABR-Affinity BioReagents

Description:... bovine rhodopsin, catalog # PA1-729. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~ 70-fold) for competitive inhibition of antibody-protein binding reactions. Storage: -20 C, Avoid Freeze/Thaw Cycles....
Company:ABR-Affinity BioReagents

Rat SCAMP 5 Neutralizing Peptide from ABR-Affinity BioReagents

Description:...MP 5, catalog # PA1-737. Using a solution with equal weights per unit volume of peptide and corresponding antibody will yield a solution with a large molar excess of peptide that is able to competitively bind the antibody. Storage: -20 C, Avoid Freeze/Thaw Cycles....
Company:ABR-Affinity BioReagents

Rat SAP97 Neutralizing Peptide from ABR-Affinity BioReagents

Description:... product and SAP97, catalog # PA1-741. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~ 70-fold) for competitive inhibition of antibody-protein binding reactions. Storage: -20 C, Avoid Freeze/Thaw Cycles....
Company:ABR-Affinity BioReagents

Rat rab 3D Neutralizing Peptide from ABR-Affinity BioReagents

Description:...ct and rat rab 3D, catalog # PA1-773. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~ 70-fold) for competitive inhibition of antibody-protein binding reactions. Storage: -20 C, Avoid Freeze/Thaw Cycles....
Company:ABR-Affinity BioReagents

Human and Mouse RAR Neutralizing Peptide from ABR-Affinity BioReagents

Description:...g # MA1-811 and PA1-811. Using a solution with equal weights per unit volume of peptide and corresponding antibody will yield a solution with a large molar excess of peptide that is able to competitively bind the antibody. Storage: -20 C, Avoid Freeze/Thaw Cycles....
Company:ABR-Affinity BioReagents
Molar in Biological Definition

Biophysics

... 6 See also 7 External links Overview Traditional studies in biology are conducted using statistical ensemble experiments, using molar concentrations of macromolecules . Because the molecules that comprise living cells are so small, techniques such as PCR amplification, gel blott...

Carbohydrate

...er projection ) Fructose ( Fischer projection ) Pure carbohydrates contain carbon , hydrogen , and oxygen atoms , in a 1:2:1 molar ratio , giving the general formula C n H 2n O n . However, many important carbohydrates deviate from this, such as deoxyribose . Sometime...

Osmosis

...ressure increases the chemical potential of the system in proportion to the molar volume ( δμ = δ P V ). Therefore, osmosis stops, when the... i.e.: Where δ P is the osmotic pressure and V is the molar volume of the solvent. For the case of very low solute concentrations, ...

Turgor

...d turgor. The osmotic pressure π of a dilute solution can be calculated using the formula where M is the molarity R is the molar gas constant T is absolute temperature (i.e. measured in kelvin ). Note the similarity of the above formula to the ideal gas law . See...
Molar in Biological Dictionary

Transposase

...s ... Tn5 transposase is the key enzyme in forming transposomes for random transposon insertions. ... of cut out fragments with transposase molar excess of 0-9x ... ... tnpR, this transposon also carries a transposase or tnpA and a β-lactamase Bla ... This process is catalysed by the Tn3 ...

Primary root

...on. process is regulated in a manner similar to bone ... start resorbing the primary root at a specific area and time, ... concept of primary molar root canals and the ... investigations of primary tooth root canal ... assessing the primary stage of root canal negotiation and ... Defi...

Premolars

... transitional teeth located between the canine and molar teeth. In humans, there are two premolars per qu...ek teeth. Premolars have deciduous (baby) teeth, molar do not. Temporomandibular joint. Molars ... Wha...tive ... ... normally 3 or 4 premolars and 3 molar teeth ... The first premolars , if present, are ...

Molar teeth

... This kind of molar is found in mammals that wear their teeth ... Teeth . Permanent (Incisor, Canine, Premolar, molar ) · Deciduous ... Third molar teeth consist of the mandibular and maxillary thi...

Bicuspid

...ollowing chart sshows when primary and permanent teeth erupt ... Second premolar (second bicuspid ) 10 to 12 years. First molar. 6 to 7 years. Second molar ... Bicuspid aortic valve is the most common malformation of the heart valves. ... Unfortunately, bicuspid aortic valves are also more prone ...
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