Models

Study Models Impact Of Anthrax Vaccine

Rapidly distributing antibiotics to peopleexposed to anthrax spores during a bioterrorist attack, could byitself, prevent about 70 percent of anthrax infections from occurring,according to researchers from the Johns Hopkins Bloomberg School ofPublic Health. To increase the prevention rate to 90 percent, theirstudy found that at least 63 percent of the population would need to beimmunized wi...

Research Using Mouse Models Reveals A Novel Key Player In The Initiation Of Colon Cancer

Gastric and colorectal cancers account for more than 1 million deaths worldwide every year and several research groups have been working to identify the molecular events that result in the initiation and progression of these tumors. It has been established that interfering with the function of one gene, called Adenomatous Polyposis Coli (APC) has a profound effect on the cells lining the innermos...

Molecular models advance the fight against malaria

Research from Dartmouth Medical School, demonstrating how malaria parasites form mutations that make them stubbornly resistant to drug therapy, may hold the key to a new treatments for a disease that afflicts more than half a billion people worldwide. The scientists developed disease models using yeast and successfully introduced five mutations that make malaria resistant to the anti-malar...

A new way to share models of biological systems

Today sees the launch of BioModels, the world's first database of annotated biological models. BioModels is the result of a collaboration led by the European Bioinformatics Institute (UK) and the SBML Team, an international group that develops open-source standards to describe biological systems. Other contributors include the Keck Graduate Institute (USA), the Systems Biology Institute (Japan) a...

Understanding biases in epidemic models important when making public health predictions

Mathematical models have become invaluable decision-making tools for public health officials. As demonstrated during the United Kingdom's foot-and-mouth epidemic of 2001, models can be useful in two ways: they can reveal the underlying characteristics of an infection and they can allow the comparison of alternative control measures. Often, however, such models make implicit assumptions that may s...

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Web-centric entrepreneurs find models that attract investment

- Five years removed from the dotcom bubble, when adolescent business models were scorching investors and questioning the value of the online world, new business models that investors find attractive are emerging. The models are both progressive in their cutting-edge approach to business and traditional in their adherence to financial rea...

Gaming technologies alter classroom, textbook models

The first annual was sponsored by <a href="http://www.ac...

Models at Medicine News

Women's Self-Esteem Not Lowered By Seeing Ultra Thin Models

Thin models, believed to set unrealistic standards of beauty are most commonly blamed for lowering self-esteem of women who watch the advertisement. Based on this trend, // a lot of marketing companies (including Dove) have started looking out for realistic-looking models to convey messages in an effective way. A new study has now revealed that moderately heavy women are more likely t...

Mouse Models To Determine The Cause Of Aggressive Leukemia

According to the research conducted by the scientists at St. Jude Children’s Research Hospital it was found that mutation and loss of tumor suppressor gene resulted in aggressive leukemias.// Researchers have used mouse models to determine the reason behind aggressive nature and drug resistant nature of the acute lymphoblastic leukemia (ALL). The investigators found that the combination...

Academy for Eating Disorders Calls for Ban on Underweight Models

The Academy for Eating Disorders, an international organization for eating disorder treatment, research and education professionals//, calls for a global ban on the use of severely underweight models in fashion shows and in fashion magazines, and encourages the industry to adopt a minimum acceptable height-to-weight ratio in keeping with the guidelines established by the World Health Orga...

Fashion Industry Takes Its Toll on Young Models

As they stride down the catwalk with their long, slender legs, they seem almost perfect and in a way untouchable, these young women who will be showing off the creations of// the top couturiers during the New York Fashion Week. But now these much-admired models who are participating in the fashion week that started Friday - for many years icons for millions of women - are having a cr...

Spanish Fashion Show Rejects Five Models as too Thin

A top Spanish fashion show, the Pasarela Cibeles, has rejected five models from its team of 69 for being too thin//,the show's nutritionist said. "Some of the girls were rejected due to a very low body mass index of 16 - the equivalent of being 1.80 meters and weighing less than 50 kg," said Susana Monereo, who sets the standards for the show with two other doctors. Althou...

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EntreMed's Aurora Kinase Inhibitor Induces Tumor Regression in Preclinical Models

ROCKVILLE, Md., June 01, 2007 /PRNewswire-FirstCall/ --EntreMed, Inc. , a clinical-stage pharmaceutical company developingtherapeutics for the treatment of cancer and inflammatory diseases,announced the presentation of preclinical results for its Aurorakinase - angiogenesis inhibitor, ENMD-981693. The data werepresented during oral and poster presentations by EntreMedscientists at the 2n...

VGX Pharmaceuticals' Novel HIV and Pandemic Influenza DNA Vaccine Candidates Trigger Robust Immune Responses and Protection in Pre-Clinical Models

MALAGA, Spain--(BUSINESS WIRE)--May 23, 2007 - VGX Pharmaceuticals'novel pandemic influenza vaccine candidates triggered protectiveimmune responses in pre-clinical challenge studies, according todata presented for the first time today at the Third InternationalConference on DNA Vaccines in Malaga, Spain. VGX scientists created four synthetic consensus DNA vaccines toprotect against a leth...

Data Presented at AACR Meeting Show Peregrine's Bavituximab Equivalent Can Generate Curative Immune Responses as Part of a Vaccine-Like Regimen in Preclinical Models of Aggressive Brain Cancer

--Immunization with a Bavituximab Equivalent and Irradiated TumorCells Increased Long-Term Survival to 57% From 0% in Controls in aPreclinical Model of Brain Cancer-- LOS ANGELES and TUSTIN, Calif., April 18, 2007/PRNewswire-FirstCall/ -- Peregrine Pharmaceuticals, Inc. , aclinical stage biopharmaceutical company developing targetedmonoclonal antibodies for the treatment of cancer and hep...

Medarex Presents Preclinical Data Demonstrating Potent Anti-Tumor Activity of Anti-CD19 and Anti-CD70 Antibody-Drug Conjugates in Cancer Animal Models

- Data presentations at American Association for Cancer Researchannual meeting - PRINCETON, N.J., April 17, 2007 /PRNewswire-FirstCall/ --Medarex, Inc. today presented preclinical data demonstrating potentanti- tumor activity from two separate studies exploring theefficacy and safety in animal models of anti-CD19 and anti-CD70antibody-drug conjugates. CD19 and CD70 are both attractive tar...

EntreMed Presents Multi-Mechanism Antitumor Data for ENMD-1420 in Preclinical Models

Tumor Inhibition Demonstrated in Lung and Colorectal Cancers ROCKVILLE, Md., April 16, 2007 /PRNewswire-FirstCall/ --EntreMed, Inc. , a clinical-stage pharmaceutical company developingtherapeutics for the treatment of cancer and inflammatory diseases,announced the presentation of results for its preclinical tubulininhibitor compounds. The data were presented by EntreMed scientistsat the A...

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