Mitochondria

Mitochondrial DNA mutations play significant role in prostate cancer

Mutations in mitochondrial DNA (mtDNA) playan important role in the development of prostate cancer, according toresearch by scientists at Emory University School of Medicine and theUniversity of California, Irvine. The findings are published onlinethis week in the Proceedings of the National Academy of Sciences(PNAS). Mitochondrial DNA, which is separate from nuclear DNA, is foundin the hun...

New mitochondrial DNA gene chip may be early cancer diagnosis tool

A pilot study at the National Institute of Standards and Technology (NIST), in support of the National Cancer Institute's Early Detection Research Network (EDRN), has validated the measurement accuracy of new techniques that use mitochondrial DNA as an early indicator for certain types of cancer. Additional results suggest that a relatively simple diagnostic test using a DNA microarray "chip" cou...

Few clues about African ancestry to be found in mitochondrial DNA

Mitochondrial DNA may not hold the key to your origins after all. A study published today in the open access journal BMC Biology reveals that fewer than 10% of African American mitochondrial DNA sequences analysed can be matched to mitochondrial DNA from one single African ethnic group. There has been a growing interest in the use of mitochondrial DNA to trace maternal ancestries, and several com...

Getting old? Slowing down? Blame inefficient mitochondria

Mitochondria are the cell's equivalent of power stations. A power station burns fuel to build up steam pressure and uses that pressure to drive a turbine linked to a dynamo. This in turn generates electricity. In mitochondria, the fuel is oxidised and builds up a pressure of hydrogen ions (protons). These force through molecular turbines and enable the cell to generate ATP, an energy unit that ca...

First direct mechanical communication of mitochondria, cardiomyocyte nucleus shown

In a paper being presented in two American Physiological Society sessions at Experimental Biology 2006, a joint Estonian-French team demonstrated "for the first time that mitochondria are able to induce nuclear deformation, suggesting that mitochondria may mechanically regulate nuclear function." The team, which has been collaborating for over 10 years, reported that it recently "found a v...

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Mitochondria at Biology Products

Mitochondria Isolation Kit for Tissue and Cultured Cells from BioChain

Description:Components in this kit are prepared with pure chemicals according to our proprietary technology. Biochains Mitochondria Isolation Kit is designed to isolating intact and active mitochondria in a fast and easy way. One kit is consisted of reagents enough for performing 100 isolations (enriching mitochondria from 10 20 g tissue or from 1x10 cells)....
Company:BioChain

Isolated Mitochondria Staining Kit from Sigma-Aldrich

Description:The kit measures mitochondria intactness and detects events that dissipate the mitochondrial membrane potential....
Company:Sigma-Aldrich

APO LOGIX - JC-1 Mitochondrial Membrane Potential Detection Kit from BACHEM

Description:In situ detection of apoptosis and mitochondrial membrane potential. The mitochondrial permeability transition event provides an early indication of the initiation of cellular apoptosis. This process is typically defined as a collapse in the electrochemical gradient across the mitochondrial membrane, as measured by the change in the membrane potential (YD). Loss of mitochondrial YD is indicative...
Company:BACHEM

MitoLight Mitochondrial Apoptosis Detection Kit from CHEMICON

Description:Disruption of the mitochondrial transmembrane potential is one of the earliest intracellular events that occur following induction of apoptosis. The MitoLight Apoptosis Detection Kit utilizes a lipophilic cation, termed as MitoLight, as a mitochondrial activity marker. MitoLight is a mitochondrial dye that stains mitochondria in living cells in a membrane potential-dependent fashion. The monomer...
Company:CHEMICON

MitoPT Detection of Mitochondrial Permeability from B-Bridge International

Description:The MitoPT kit is used in conjunction with your existing apoptosis protocols. Grow your cells in culture and induce apoptosis according to your existing procedure (also reserve a non-induced population of cells as a negative control). Once you have induced apoptosis in your cells, add the 1X MitoPT solution to each population and incubate the cells for an additional 15 minutes. During this incuba...
Company:B-Bridge International

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Mitochondria at Biology Technology

The measurement of DNA condensation and mitochondrial changes during apoptosis and necrosis in cell based assays

Apoptosis represents a gene-directed, morphologically and biochemically distinct form of programmed cell death. Inappropriate control of apoptosis is associated with a variety of disease states such as cancer, AIDS, neurode...

REPLI-g Mitochondrial DNA Kit

The REPLI-g Mitochondrial DNA Kit provides specific and uniform whole genome amplification from human mitochondrialDNA in total DNA samples. The simple procedure enriches for mitochondrial DNA with minimal contamination from nuclearDNA, thus avoiding the need...

Mitochondria at Biology Dictionary

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Mitochondria at Medicine News

Citrinin, a fungal toxin, induces apoptosis via mitochondrial pathway

The Mycotoxin citrinin (CTN) is a secondary metabolite produced by several fungal species that belong mainly to the genus Penicillium and Monascus. It is widely considered as a hazard contaminant of foods// and feeds, including corn, wheat, rice, barley and nuts, and is known to be cytotoxic and genotoxic to various mammalian cells. CTN has been suggested as a causative factor in renal disease am...

Researchers Have Linked Rett Syndrome to Mitochondrial Gene

Researchers from the laboratory of Adrian Bird, a molecular geneticist at the University of Edinburgh, Scotland, had announced on 23rd June// that the abnormally high levels of a protein called Uqcrc1 in the brains of mouse used as models of Rett Syndrome is causing its mitochondria, which are the powerhouses of the cells to work overtime. Dr. Bird stated that this is the first time that mitochon...

MitoChip v2.0 – the new Mitochondrial DNA sequencing too

The latest versions of High-tech laboratory tools such as computers with greater analytical capacities are updated publicly. The NIH grantees have developed a second// generation "lab on a silicon chip" called the MitoChip v2.0. This can for the first time sequence all mitochondrial DNA quickly and reliably. Their report will be published in the September issue of the Journal of Molecular Diagnos...

High -tech Mitochondrial DNA Sequencing Tool Updated

With the increase of analytical capabilities of high-tech laboratory tools, like computers, their updating is often conducted publicly . NIH grantees report they have// developed a second generation "lab on a silicon chip" called the MitoChip v2.0 that for the first time rapidly and reliably sequences all mitochondrial DNA, in the September issue of the Journal of Molecular Diagnostics. Mitochond...

Mitochondrial Protein Maintains Appetite During Fasting

Researchers at Yale School of Medicine have found that a thyroid hormone in the brain is linked to the “uncoupling” protein UCP2, which can maintain appetite during periods// of fasting so that the body is ready to eat when food is reintroduced. Published in the January issue of Cell Metabolism, the study was conducted by observing the behavior of mice that fasted for 24 hours. The re...

Mitochondria at Medicine Products

Liquichek Autoimmune Controls - Anti-Mitochondrial

Description:Liquichek Autoimmune Controls are individual controls for monitoring the performance of autoimmune assays....
Company:Bio-Rad Laboratories

Anti-Mitochondrial M2 Antibody, IgG (ELISA)

Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...
Company:ARUP Laboratories

Anti-Mitochondrial Antibody (AMA) Test Kit

Description:Inverness Medical Professional Diagnostics is a leading provider of immunofluorescence assays, with an extensive IFA and DFA test menu that includes kits for autoimmune diseases, infectious diseases and STDs as well as miscellaneous conjugates and components. Our Impact IFA Test Systems give you a wide assortment of substrates and kit sizes to choose from. Kit components include substrate slides,...
Company:Inverness Medical Innovations

Mitochondria ELISA Test Kit

Description:Our ELISA products for autoimmune testing feature single-well ANA screen and ENA screen ELISAs, as well as specific reflex tests including dsDNA, and 6 individual ENA kits: Sm, Sm/RNP, SS-A (Ro), SS-B (La), Scl-70 and Jo-1. In addition, our autoimmune ELISA family includes a full line of products for Cardiolipins (IgA, IgG, IgM), Thyroglobulin, Thyroid Microsomal, MPO, PR3, Rheumatoid Factor and...
Company:Inverness Medical Innovations

Mitochondrial M2 Antibody, IgG (ELISA)

Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...
Company:ARUP Laboratories

Mitochondria at Medicine Technology

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