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Mismatch in Medical News

New decision model seeks to avert flu vaccine mismatch of 2007-2008 season

To avoid producing vaccines that treat the wrong strains during flu season, the FDA should consider deferring some of its selections as well as other changes to the vaccine composition, according to a study by two decision analysts published in a journal of the Institute for Operations Research an...

MDS Nordion Submits Expression of Interest Proposal to Government of Canada on Medical Isotope and Generator Production

...gulation, Canadian Nuclear Safety Commission, stated "The issue is not whether, necessarily, there's any problem with a positive coefficient. It was a mismatch between the (value) predicted in their safety case in the computer codes that said it should be negative and the actual measurements in the reactor th...

Innovative New Wellness and Nutrition Program Leverages Latest Understanding of Relationship Between Diet and Genes

... Gene Smart(TM) Takes New Approach to Diet and Exercise to Live Longer, Healthier Lives WINSTON-SALEM, N.C., June 11 /PRNewswire/ -- The mismatch between today's typical diets and our genes has been a major contributor to the nation's health crisis, including obesity and chronic inflammatory dis...

Gene Screen May Predict Colon Cancer's Return

... the two older screens. "The new tool is an independent important variable," Kerr said. "There would be 70 percent of patients in whom T-stage and mismatch will not be informative and we think that, in this group, the new tool will provide a useful addendum to the clinical decision-making process." M...

Genomic Health's Oncotype DX(R) Colon Cancer Test Predicts Individualized Recurrence Risk for Stage II Colon Cancer Patients

...nt clinical value beyond standard measures. The study showed that the colon cancer Recurrence Score maintained significance (p=0.008), independent of mismatch repair (MMR), also known as MSI (Microsatellite Instability), T-stage, nodes examined, grade and lymphovascular invasion. These findings, which ...

American Transplant Congress 2009: New Investigator Forum Presents Cutting Edge Research

...e RNA and microRNA biology Cholangiocarcinoma in Liver Transplantation Transplant Tourism Clinical Trials Impact of the Acceptable mismatch in Europe on the Transplantation Rate of Highly Sensitized Patients ...many more vital presentations For more information about the A...

Brain Scans Shed Light on Dyslexia

... mismatch occurs between seeing letter and the sound it represents, study suggests ...ow the minds of people with dyslexia work. The key problem seems to be a mismatch between seeing the letter and connecting it to the sound it represents or v...

Living Kidney Donation Chains May Help More Get Transplants

...rocurement and Transplantation Network. Many of these people have a friend or family member who is willing to donate a kidney but can't because of a mismatch or other problem. People can find themselves unable to donate to a loved one if their blood type doesn't match or if they've developed certain anti...

Also in the Feb. 24 JNCI

.... John's, Newfoundland, and colleagues tested the ability of four models to distinguish between individuals who did and did not carry mutations in DNA mismatch repair genes. They examined a series of 725 colorectal cancer patients whose mutation status was known. By analyzing such factors as the age of the...

David G. Mutch Elected 41st President of the Society of Gynecologic Oncologists

...book chapters on the treatment of cancers of the female reproductive tract. Currently, Dr. Mutch is the co-PI on an NIH grant looking at defective DNA mismatch repair in endometrial cancers. Prior to being named SGO's president, Dr. Mutch served as the Society's President Elect, was the Chair of the SGO...
Mismatch in Medical Technology

EnVivo Pharmaceuticals Announces Initiation of Clinical Safety and Biomarker Study of Alpha-7 Nicotinic Agonist, EVP-6124, in Patients with Schizophrenia

...logy markers (the P50 auditory evoked response and mismatch negativity) in Schizophrenia patients. The princ...f an alpha-7 nicotinic agonist in Schizophrenia. mismatch negativity is another electrophysiological biomark...effects of EVP-6124 on the P50 evoked response and mismatch negativity may be very useful in determining the t...

Memory Pharmaceuticals Reports Fourth Quarter and Full Year 2007 Financial Results

...y Pharmaceuticals announced that it plans to conduct a clinical study of MEM 3454 on two biomarkers of schizophrenia, P50 sensory gating and mismatch negativity, in patients with schizophrenia. The biomarker study, and additional formulation and manufacturing activities for MEM 3454, will...

Memory Pharmaceuticals & Roche Expand Development Program for MEM 3454 in Schizophrenia

...riod. The primary objective of the trial is to study P50 sensory gating and mismatch negativity as potential efficacy biomarkers for nicotinic alpha-7 agonists, such as MEM 3454, in schizophrenia. P50 sensory gating and mismatch negativity are two neurophysiological measurements that have been shown to ...

Roche responds to announcement of 'IDEAL' hepatitis C trial results

...cal ribavirin regimens. A third arm was added to the study in which patients received PEGASYS 180 mcg with a different ribavirin dosing schedule. This mismatch of ribavirin dosing introduces several potential biases into the study because experts agree that an optimized dose of ribavirin, with either pegylate...

Somanta Announces the Presentation of Alchemix Data at The American Association for Cancer Research Annual Meeting

...os Angeles. The poster presentation is entitled "Cytotoxicity of novel alkylating anthraquinones in cells with DNA Nucleotide Excision Repair and DNA mismatch Repair defects," and focuses on structure-activity studies on the company's novel technology for targeting and irreversibly binding to DNA / DNA proce...
Mismatch in Medical Products

Foundation Total Shoulder System

Description:...are index. A/P and lateral fins with holes for suture attachment and rotational stability. Proximal medial hole, humeral / glenoid diametral curvature mismatch for optimizing natural joint translation. Rough textured proximal surface to provide enhanced proximal fixation. Distal grooves for rotational resista...
Company:Encore Medical Corporation
Mismatch in Medical Definition

Acute care

...th care crisis in the US is the result of the growing need for acute care despite a decrease in the number of facilities which provide that care. This mismatch has resulted from the dramatic increase in the number of patients who are uninsured or underinsured, and therefore unable to pay for services rendered...
Mismatch in Biological News

Extraterrestrial platinum was 'stirred' into the Earth

...tanding the variations in isotopic ratios of osmium with time. Osmium isotopes are widely used as tracers of mantle processes, but there has been a mismatch between signals from osmium and from other important isotopic tracer systems which has eluded explanation until now. Co-authors Dr Marco Fiorentini ...

Aussie meat ants may be invasive cane toad's Achilles' heel

...e them eating small toads, so we suspected that there might be some kind of mismatch between the invader and its newly invaded range, for example something abou...uld be used to snare invasive species elsewhere. "The end result of this mismatch between traits of metamorph cane toads, which evolved in the Americas, and ...

'Strained' quantum dots show new optical properties

...s, advanced color displays, and more efficient solar panels, Nie adds. A mismatch between the lattices of the semiconductors making up the inner core and out...e blood." "Core-shell nanocrystals are all expected to have some lattice mismatch between the core and the shell, so the strain effect is a general phenomeno...

Springer launches Food Security

...ial and (2) to address the means by which these constraints may be overcome. Food Security will cover the following topics: global food needs, the mismatch between population and the ability to provide adequate nutrition, global food potential, natural constraints to satisfying global food needs, nutritio...

Key to function of dinosaur crests found in brain structure

...in and nasal passages are," said Evans. "From there, the anatomy of these missing soft parts is easily interpreted." The CT scan results revealed a mismatch between the external shape of the crest and the internal shape of the nasal passages in closely related species, suggesting a special function for the...

Brain structure provides key to unraveling function of bizarre dinosaur crests

...n and nasal passages are," said Evans. "From there, the anatomy of these missing soft parts is easily interpreted." The CT scan results revealed a mismatch between the external shape of the crest (which no doubt functioned as a visual display) and the internal shape of the nasal passages in closely relate...

Duke team explains a longtime visual puzzler in new way

... was published in PNAS Early Edition online on October 13. Other explanations of the flash-lag effect have included theories that the effect is a mismatch between systems dedicated to the perception of speed and the perception of position, and also theories of how stimuli are integrated over time. Th...

ORNL researchers analyze material with 'colossal ionic conductivity'

...an, for example, an electron. "The new layered material solves this problem by combining two materials with very different crystal structures. The mismatch triggers a distortion of the atomic arrangement at their interface and creates a pathway through which ions can easily travel," Varela said. Other ...

New electrostatic-based DNA microarray technique could revolutionize medical diagnostics

...ges in surface charge density as a result of specific DNA hybridization can be detected and quantified with 50-picometer sensitivity, single base-pair mismatch selectivity, and in the presence of complex backgrounds. Furthermore, our electrostatic detection technique should render DNA and RNA microarrays suff...

Global warming linked to caribou-calf mortality

...rial mammals. "Our work is the first documentation of a developing trophic mismatch in a terrestrial mammal as a result of climatic warming," said Post. "And the rapidity with which this mismatch has developed is eye-opening, to say the least." While Post and Forchham...
Mismatch in Biological Technology

RT-PCR Primer Sets for Human and Mouse Mismatch Repair Genes

Primer sets facilitate study of DNA mismatch repair Mark Dycaico Stratagene Cloning Systems Stratagene has designed RT-PCR primer sets from the cDNA sequences of mismatch repair genes. These genes code for specialized proteins that participate in correcting areas of ...

New statistical technique improves precision of nanotechnology data

...cs. "The curves should have been symmetric. To address this issue, we developed a new modeling technique that uses the data itself to filter out the mismatch step-by-step using the regression technique." Ideally, researchers would search out and correct the experimental causes of these data errors, but b...

Real Time Genomics to Show SLIM Search(TM) Technology on Windows HPC Server 2008 at Bio-IT World Conference

...is to researchers using next generation DNA sequencing technologies. The company is building genomics applications based on its own fast, accurate and mismatch tolerant read mapping and alignment algorithm. Real Time Genomics is a private, San Francisco based company backed by investment from Catamount Ventur...

Transgenomic Completes Licensing Option With Dana-Farber Cancer Institute on Cold-PCR for Enrichment of DNA Mutations

...reviewed publications. As an alternative offering, Transgenomic's SURVEYOR Nuclease cleaves such heteroduplexes with high specificity at sites of base mismatch or small insertions/deletions. It has a proven track record as a robust and reliable tool in analyzing DNA variations, especially where the mutant all...

Using a grating with a grade, engineers trap a rainbow

...erials. But light is more difficult to control at the nanoscale because of natural limits on its diffraction, or ability to resolve. "There is a mismatch between nanoelectronics and nanophotonics," says Gan. "Because of the diffraction limit of light, optical circuits are now much larger than their elec...

Memory Pharmaceuticals Reports First Quarter 2008 Financial Results

...armaceuticals announced that it plans to conduct a clinical study of R3487/MEM 3454 on two biomarkers of schizophrenia, P50 sensory gating and mismatch negativity, in patients with schizophrenia. External costs of the biomarker study, and additional formulation and manufacturing activities fo...

Treatment with Paliperidone ER May Be Associated with Significantly Reduced Use of Mental Health Resources

...ations include the lack of a control group; pre/post design comparing historical data with data collected in the trials could create a bias due to the mismatch in settings; and patients may have had more frequent contact with treating physicians and investigators during the trial period which could favor the ...

VaxGen Issues Rebuttal to MedCap Letter

... price following the merger announcement. This drop was and remains very disappointing. VaxGen believes it is largely attributable to a mismatch between the expectations of certain stockholders related to asset value and transaction type, and transactions that were actually availa...

NIST demos industrial-grade nanowire device fabrication

...h-temperature process, the gold deposits bead up into nanodroplets that act as nucleation points for crystals of zinc oxide, a semiconductor. A slight mismatch in the crystal structures of zinc oxide and sapphire induces the semiconductor to grow as a narrow nanowire in one particular direction across the waf...

Lessons in Offshore Software Development

...nd communicating requirements, designing the software, tracking development and making sure the software matches the specs. The goal is to avoid a mismatch between expectations and deliverables. There can be problems with communication and understanding of requirements. It is even more important to docume...
Mismatch in Biological Products

Bacterial Strain BMH 71-18 mutS, Glycerol Stock (noncompetent) from Promega

Description:... BMH 71-18 mutS and ES1301 mutS are mismatch repair minus strains of E. coli. Use of these strains prevents repair of the newly synthesized unmethylated strand (1), leading to high mutation effic...
Company:Promega

Bacterial Strain ES1301 mutS, Glycerol Stock (noncompetent) from Promega

Description:... BMH 71-18 mutS and ES1301 mutS are mismatch repair minus strains of E. coli. Use of these strains prevents repair of the newly synthesized unmethylated strand (1), leading to high mutation effic...
Company:Promega

Rice microRNA Microarray from LC Sciences

Description:...control probes spatially distributed across the array, signal intensities, spot uniformity, cross-array spot-to-spot uniformity, and perfect-match vs. mismatch specificities are thoroughly evaluated. LC Sciences LC Sciences is a genomics and proteomics company offering innovative, customizable, and compreh...
Company:LC Sciences

Arabidopsis microRNA Microarray from LC Sciences

Description:...control probes spatially distributed across the array, signal intensities, spot uniformity, cross-array spot-to-spot uniformity, and perfect-match vs. mismatch specificities are thoroughly evaluated. LC Sciences LC Sciences is a genomics and proteomics company offering innovative, customizable, and compreh...
Company:LC Sciences

Fishes microRNA Microarray from LC Sciences

Description:...control probes spatially distributed across the array, signal intensities, spot uniformity, cross-array spot-to-spot uniformity, and perfect-match vs. mismatch specificities are thoroughly evaluated. LC Sciences LC Sciences is a genomics and proteomics company offering innovative, customizable, and compreh...
Company:LC Sciences

Cow microRNA Microarray from LC Sciences

Description:...control probes spatially distributed across the array, signal intensities, spot uniformity, cross-array spot-to-spot uniformity, and perfect-match vs. mismatch specificities are thoroughly evaluated. LC Sciences LC Sciences is a genomics and proteomics company offering innovative, customizable, and compreh...
Company:LC Sciences

Maize microRNA Microarray from LC Sciences

Description:...control probes spatially distributed across the array, signal intensities, spot uniformity, cross-array spot-to-spot uniformity, and perfect-match vs. mismatch specificities are thoroughly evaluated. LC Sciences LC Sciences is a genomics and proteomics company offering innovative, customizable, and compreh...
Company:LC Sciences

Viruses microRNA Microarray from LC Sciences

Description:...control probes spatially distributed across the array, signal intensities, spot uniformity, cross-array spot-to-spot uniformity, and perfect-match vs. mismatch specificities are thoroughly evaluated. LC Sciences LC Sciences is a genomics and proteomics company offering innovative, customizable, and compreh...
Company:LC Sciences

Soil Nematode microRNA Microarray from LC Sciences

Description:...control probes spatially distributed across the array, signal intensities, spot uniformity, cross-array spot-to-spot uniformity, and perfect-match vs. mismatch specificities are thoroughly evaluated. LC Sciences LC Sciences is a genomics and proteomics company offering innovative, customizable, and compreh...
Company:LC Sciences

Mammals microRNA Microarray from LC Sciences

Description:...control probes spatially distributed across the array, signal intensities, spot uniformity, cross-array spot-to-spot uniformity, and perfect-match vs. mismatch specificities are thoroughly evaluated. LC Sciences LC Sciences is a genomics and proteomics company offering innovative, customizable, and compreh...
Company:LC Sciences
Mismatch in Biological Dictionary

Post-meiotic segregation

... recombination at HIS4. ... Failure to repair the mismatch will result in a post meiotic segregation (P...st meiotic segregation increased 2) is a DNA mismatch repair protein ... nonpolyposis colorectal can...les. ... Post Meiotic Segregation 2. DNA mismatch repair protein ... Post Meiotic Segregatio...

MutS

...asymmetric, and ... MutS protein initiates mismatch repair with recognition of a non-Watson-Crick ......itute ... MutS and MutL are involved in ... DNA mismatch repair protein MutS , type 1. DNA mismatch repair protein, MSH2 ... The European Bioinfor...

MSH2

...an mutator gene homolog MSH2 and its association with hereditary ... mismatch Repair Factor MSH2 -MSH3 Binds and Alters the Conformation of Branched ...... Rabbit polyclonal to MSH2 . ... MSH2 is involved in DNA repair as a mismatch repair protein, and ... MSH2 antibody - related products: Products for...

Mismatch repair

... DNA mismatch repair is a system for recognizing and repairing ...s well as repairing some forms of DNA damage . mismatch repair (MMR)--Correction of mismatched nucleotides and small loops. The mechanism of mismatch repair was first thoroughly studied in E. coli....

Heteroduplex Dna

... recombination. provides a convenient addition to existing DNA ... Heteroduplex constructs have. been widely used in studying mechanisms of DNA mismatch ... ...

DNA repair

...age to the DNA molecules that encode its genome. In human cells, both normal metabolic activities and environmental factors such as UV... DNA mismatch repair is a system for recognizing and repairing erroneous insertion, deletion and mis-incorporation of bases that can arise during DNA replic...
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