Researchers make headway in mystery of migraines
Scientists at the MUHC have made progress in understanding what causes migraines. The research, published in the new issue of the Proceedings of National Academy of Sciences (PNAS), reveals how gene mutations known to cause a form of inherited migraine--the kind that cause debilitating headaches and light flashes known as auras--target a cellular process involved in brain cell communication....Device effective in zapping the pain out of migraines
An electronic device designed to "zap" away migraine pain before it starts may be the next form of relief for millions of people who suffer from the debilitating disease. The study, led by the Ohio State University Medical C...Mice with a migraine show signs of brain damage
Migraines may be doing more than causing people skull-splitting pain. Scientists have found evidence that the headaches may also be acting like tiny transient strokes, leaving parts of the brain starved for oxygen and altering the brain in significant ways. A paper describing the work by neuroscientists at the University of Rochester Medical Center appeared online April 29 in Nature Neuros...New FDA Approved Drug To Treat Migraine
Axert has been approved by the FDA for the acute treatment of migraine with or without aura in adults. This drug targets serotonin receptors and act against migraine headaches by inducing the constriction...New Modality in Migraine Management
Texas researchers have come out with a new way of administration of drug that treats migraine.Giving migraine patients the drug valproate sodium "rapidly and forcefully" eases severe headaches without side effects. Dr. John Claude Krusz of Anodyne PainCare in Dallas, in his study, which included 85 patients who had experienced no relief after treatment with standard therapies,//treated...The best treatment for migraine
A class of drugs known as the triptans are known to help counter the unpleasant symptoms of a migraine headache. Since there are seven different triptan drugs available, it is very diffcult to choose the drug. Researchers at the University of Netherlands have carried out an analysis of all the clinical trials on the triptans, covering over 18,000 patients. They find that in comparis...Magnesium sulfate offers no help in migraine treatment
Addition of intravenous magnesium sulfate to standard emergency department migraine therapy with metoclopramide, appears to reduce rather than enhance the effectiveness of treatment.// Dr. Jill Corbo, and colleagues from the Albert Einstein College of Medicine in the Bronx, New York, note that there is evidence that magnesium may be helpful in the treatment of migraine headache and that studies i...Trexima (Sumatriptan/Naproxen Sodium) Demonstrated Migraine-Free Response Across Multiple Attacks
Nearly Twice as Many Patients Taking Trexima were Migraine FreeCompared to Placebo CHICAGO, June 08, 2007 /PRNewswire/ -- New data from two largetrials show that Trexima, when taken early, was nearly twice aseffective as placebo in eliminating all traditional migrainesymptoms at two and four hours across multiple attacks with justone tablet. The findings will be presented tomorrow at the...NuPathe Reports Positive Phase One Results for NP101 Transdermal Therapy for Acute Migraine
CONSHOHOCKEN, Pa.--(BUSINESS WIRE)--Jun 8, 2007 - NuPathe Inc., aprivately held specialty pharmaceutical company, today announcedpositive results from an initial Phase I study of NP101SmartRelief, a novel treatment for acute migraine being developedby NuPathe. NP101 combines NuPathe's SmartRelief(TM) proprietaryiontophoretic transdermal technology with sumatriptan, the mostwidely prescri...