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Microparticles in Medical News

Proteins in Microparticles Identified in Women With Preeclampsia

Proteins released by the placenta may damage blood vessels in women with preeclampsia (PE).// In PE, a complication of pregnancy linked to life-threatening increases in high blood pressure after 20 weeks of gestation, it has long been recognized that substances called "microparticles" released b...

Microscopic 'beads' could help create 'designer' immune cells that ignore transplanted organs

...sfully in mice with skin grafts. The degradable microparticles deliver the most powerful known form of HLA-G, a n...pically show the immune system what to attack. The microparticles are given right after a transplant, just as dendri...gy. When researchers compared the success of HLA-G microparticles with the dendritic cell marker to those without a ...

Virus filters for medical diagnosis

...r Biomedical Engineering IBMT came across an unexpected phenomenon: stable turbulence structures formed in the microscale pump channels. The nano- and microparticles actually intended to verify the pump effect accumulated in large quantities in the channels. The vortex patterns completely filled the whole microchan...

Tiny capsules deliver

... system, a tiny spherical container averaging less than 5 microns or the diameter of the smallest pollen grains. The spheres are formed around solid microparticles that are either the drug to be delivered or a substance that can be removed later leaving a hollow sphere for liquid drugs. They reported their result...

Cell phones using lens-free imaging promise to improve health monitoring

...other fluid sample. LUCAS captures an image of the microparticles in the solution using a sensor array. Because red blood cells and other microparticles have a distinct diffraction pattern, or shadow ima... a two-dimensional holographic shadow image of the microparticles can be captured that contains much more informatio...

Weill Cornell Medical College receives 2 $100,000 grants for innovative global health research

...th if successful. Dr. Anne Moscona and colleagues will research a new antiviral approach to treating respiratory viral disease that uses engineered microparticles to hijack the mechanism that the viruses use to enter cells. Acute respiratory infections account for close to 20 percent of deaths in young childr...

HIV conquers immune system faster than previously realized

...ected T cells has already been established. Through a series of in vitro laboratory experiments with peripheral blood cells, scientists found that microparticles suppressed levels of IgG and IgA, two classes of antibodies that normally would protect a person against infection. "This is important because many sc...

Novel 3-D cell culture model shows selective tumour uptake of nanoparticles

...del now reported, these two techniques have been brought together for the first time. Brain tumour cell aggregates were labelled with fluorescent iron microparticles and grown on normal newborn rat-brain tissue slices. The double cell labelling technique allowed investigation of tumour cell invasion into brain tis...

A New Inexpensive Technology for Multiplexed Detection

...y aligned for accurate scanning. Each time a particle flows past a detector, its barcode is read and the corresponding target is quantified. The microparticles are inexpensive because they can be produced efficiently in a single step. The design of the particles also makes the scanning devices cheaper. With m...
Microparticles in Medical Technology

Non-Invasive Diagnostic Tests for Celiac Disease

...ion of antibody are available from Bio-Rad Laboratories, Scimedx Corporation and IMMCO Diagnostics, Inc. The FDA has also approved a fluorescent-based microparticles immunoassay developed by Biomedical Diagnostics. Even though the predictive value of anti-gliadin antibody (AGA) testing is not as strong as the...
Microparticles in Medical Products

Sculptra® Injectable Poly-L-Lactic Acid

Description:... SCULPTRA™ is an injectable implant that contains microparticles of poly-L-lactic acid, a biocompatible, biodegradable, synthetic polymer from the alpha-hydroxy-acid family. SCULPTRA is reconstituted prior to use by...
Company:Dermik Laboratories

STA LIATEST FREE PROTEIN S

Description:... Immuno-turbidimetric assay for Free Protein Sby STA© Analyzers. Suspension of microparticles coated with monoclonal antibodies to Free Protein S....
Company:Diagnostica Stago, Inc.

BacLite™

Description:...tive ID and AST result to the clinician. The sensitivity of AK technology combined with specific microorganism extraction methods based on magnetic microparticles makes the BacLite an extremely powerful and versatile diagnostic tool. Identification and sensitivity tests can be performed on culture isolates or di...
Company:Acolyte Biomedica Ltd
Microparticles in Biological News

Drug-embedded microparticles bolster heart function in animal studies

Researchers at Emory University and Georgia Institute of Technology have developed tiny polymer beads that can slowly release anti-inflammatory drugs and break down into non-toxic components. When injected into rats' hearts after a simulated heart attack, the drug-embedded "microparticles" redu...

Laughing hyenas, wailing levees, the sound of cheese and blaring bagpipes

...o stick to the cells that line blood vessels. This technique, ultrasound-mediated gene delivery (UMGD), exploits the properties of contrast agents, microparticles that are normally injected into the body to improve the quality of ultrasound images. In UMGD, the tiny particles are microbubbles composed of pockets...

Ancient geologic escape hatches mistaken for tube worms

...trapped beneath the seafloor in the form of gas hydrates. If these hydrates were to be destabilized, methane bubbles could release large quantities of microparticles to the ocean bottom. This release would cloud up the deep ocean and the effect would be akin to fouling up the atmosphere with a dense smog. Given tha...

Ship-in-a-bottle kit on a microchip

...ld. The scientists construct the magnetic field with four coils so that the microparticles are literally remote controlled and form diamond shapes or cog wheels. "The...ains Tobias Sawetzki, who a doctoral student is working on the project. The microparticles then remain in this shape as long as the magnetic field is switched on. ...

Children's National researchers develop novel anti-tumor vaccine

...em, developed in the laboratory of Children's National Chief of General and Thoracic Surgery Anthony Sandler, MD , involves the creation of synthetic microparticles known as "immune stimulatory antigen loaded particles" (ISAPs), that consist of tumor antigens (proteins) from the specific tumor to be targeted, as w...

Biodegradable polymers show promise for improving treatment of acute inflammatory diseases

...o disease locations in the body. "The polyketal microparticles we developed are simply a vehicle to get the drugs...ell culture experiments have demonstrated that the microparticles degraded more rapidly in cells that overproduced s...at inflammatory bowel disease. "We think these microparticles are going to be fantastic for oral drug delivery b...

Can micro-scaffolding help stem cells rebuild the brain after stroke?

...s as a result of stroke. Speaking at the conference in Edinburgh, Dr Mike Modo from the Institute of Psychiatry will explain how combining scaffold microparticles with neural stem cells (NSCs) could regenerate lost brain tissue. Strokes cause temporary loss of blood supply to the brain which results in areas ...

Scientists ask whether microscaffolding can help stem cells rebuild brain after stroke damage

...ill hear today (10 April). Speaking at the conference in Edinburgh, Dr Mike Modo from the Institute of Psychiatry will explain how combining scaffold microparticles with neural stem cells (NSCs) could regenerate lost brain tissue. Strokes cause temporary loss of blood supply to the brain which results in areas ...

MIT sculpts 3-D particles with light

... CAMBRIDGE, Mass.--MIT engineers have used ultraviolet light to sculpt three-dimensional microparticles that could have many applications in medical diagnostics and tissue engineering. For example, they could be designed to act as probes to detect certai...

Novel 3-D cell culture model shows selective tumor uptake of nanoparticles

...model now reported, these two techniques have been brought together for the first time. Brain tumor cell aggregates were labeled with fluorescent iron microparticles and grown on normal newborn rat-brain tissue slices. The double cell labeling technique allowed investigation of tumor cell invasion into brain tissu...
Microparticles in Biological Technology

Xspray Expands to Meet Pharma's Interest in its Ground-Breaking Particle Production Technology

... STOCKHOLM, April 27 /PRNewswire/ -- Xspray microparticles AB, the Swedish life science technology company, h...antage of them." About Xspray Xspray microparticles AB is a Swedish life science technology company wi...facture of pharmaceutical particles. Xspray microparticles has its headquarters and development laboratories ...

Savara Expands Board of Directors, Appoints Three New Members

...ncreasing interest in our platform NanoCluster technology." "Savara's formulation technology combines the features of nanoparticles in structured microparticles to yield a powder with ideal aerodynamic properties for inhalation. Their approach is unique and addresses many of the challenges associated with exis...

Soliris(R) Reduced Measures of Thrombosis and Inflammation, and Decreased Indicators of Pulmonary Hypertension, in Studies of Patients with PNH

..., including LDH levels (p=0.0001), D-dimers (p=0.0057), thrombin-antithrombin complex or TAT (0.01), interleukin 6 or Il-6 (p=0.04), and tissue factor microparticles or TFMP (0.02) during the four-week induction phase of treatment. All decreases in D-dimers, TAT, Il-6, TFMP, and LDH were sustained in the maintenanc...

MagSense to Exhibit Its Scientific and Clinical Applications at International Magnetic Carriers Conference

...eparation technologies for life sciences research and biochemical production. The enhanced magnetic properties and uniformity of its superparamagnetic microparticles are ideally suited for pharmaceutical, biotechnology, and diagnostics companies, as well as research centers and laboratories of academic, government,...

JCI table of contents: April 22, 2008

...t for the development of anti-thrombotic drugs. microparticles are small particles released from cells when they ...was shown to mediate binding of human platelets to microparticles derived in vitro from the cells that would be damaged by blood vessel injury and to microparticles isolated from healthy people. Further analysis ind...

Immucor To Acquire BioArray Solutions Ltd.

...yping) using its proprietary BeadChip(TM) system for molecular medicine. BioArray's BeadChip(TM) system deploys planar arrays of proprietary encoded microparticles to perform rapid and reliable molecular analysis of nucleic acids and proteins. Its recently launched transfusion genotyping system is currently insta...

'Two-Faced' Particles Act Like Tiny Submarines

...cles leads to unbalanced liquid flows and nonlinear, induced-charge electrophoretic motion. We report experimental observations of the motion of Janus microparticles with one dielectric and one metal-coated hemisphere induced by uniform fields of frequency 100Hz-10kHz in NaCl solutions. The motion is perpendicular ...

Two-faced miniatures

...escribed in the journal Angewandte Chemie, with the use of stop-flow interference lithography, the team has even been able to produce Janus particles, microparticles with two chemically different hemispheres. Our new method is a combination of phase mask interference lithography and mirofluidic flow lithography, ...

New DNA-based technique for assembly of nano- and micro-sized particles

... formations. The researchers performed the experiments on gold nanoparticles measuring billionths of a meter and polystyrene (a type of plastic) microparticles measuring millionths of a meter. These particles served as models for the possibility of using the technique with other small particles. The scientis...

Protein Depletion for Plasma and Serum Proteomic Analysis

...SF), urine [16-18], saliva [19-21], interstitial fluid [22], amniotic fluid [23-26], follicular fluid [27], and platelet-derived microparticles in blood [28] are also now being investigated for diagnostic biomarker discovery. In addition, proteomic profiles of human tissu...
Microparticles in Biological Products

ELISA Kit for Hepatitis B Surface Antigen Using GoldMag-AS Microparticles from BioChain

Description: The ELISA Kit for Hepatitis B Surface Antigen (HBsAg) is an in vitro enzyme immunoassay for the detection of HBsAg in human serum or plasma....
Company:BioChain

PDS-1000 He System from Bio-Rad

Description:... The biolistic PDS-1000 He system uses a burst of high-pressure helium gas to accelerate micron-size nucleic acid-coated gold or tungsten microparticles to velocities necessary to transfect cells, tissues, or organelles without dependence or interaction with the cell surface. The system includes helium...
Company:Bio-Rad
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