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Microinjection in Medical News

1st EMEA application filed for product using innovative intradermal microinjection system BD Soluvia

Franklin Lakes, NJ, USA (February 13, 2008) -- Sanofi Pasteur, the vaccines division of sanofi-aventis Group, has submitted the first application in Europe to deliver a vaccine using BD Soluvia, the innovative microinjection system developed by BD (Becton, Dickinson and Company). The submission ...

Microbiotic technology developed for microinjection of zebrafish embryos

Funded by an NSERC Idea to Innovations grant and an Ontario Early Researcher Award, Prof. Yu Suns group, the Advanced Micro and Nanosystems Laboratory ( http://amnl.mie.utoronto.ca ) at the University of Toronto (U of T) recently developed a microrobotic technology for automated microinjection of ...

Sanofi-aventis Announces Good First-quarter 2009 Performance

..., the European Commission granted marketing authorization for Intanza (R) , the first influenza vaccine to be administered using a novel intradermal microinjection system. The benefits of this vaccine, in particular its convenience and ease of administration, should help improve vaccination coverage in Europe. ...

Sanofi-aventis: Encouraging First-Quarter 2008 Results Further Positive Phase III Results for Eplivanserin

...keting authorization application with the European Medicines Agency (EMEA) for the first influenza vaccine delivered by an innovative intradermal (ID) microinjection system. The file was accepted for review by the EMEA. Also in February 2008, sanofi pasteur announced the signing of an agreement with Statens Serum...

Penn Veterinary Medicine report new strategy to create genetically modified animals

... also demonstrates that germline transduction and germ cell transplantation in large animals provides an approach that is potentially less costly than microinjection and cloning, the traditional methods used to generate transgenic large animal models for biomedical research. Researchers used mouse germ cells har...
Microinjection in Medical Technology

Researchers Create First Targeted Knockout Rats Using Zinc Finger Nuclease Technology

...or embryonic stem cells and allows rapid creation of new animal models." In the study published in Science titled "Knockout Rats via Embryo microinjection of Zinc Finger Nucleases," (Geurts, et al.) scientists used ZFNs to knock out an inserted reporter gene and two native rat genes without causing measu...
Microinjection in Medical Products

IX51 Inverted System Microscope

Features:...ion pillar and has a 45mm working distance and 0.5NA to provide excellent 3-D relief images of specimens in plastic vessels, especially oocytes during microinjection observations ...
Company:Olympus America Scientific
Microinjection in Biological News

AVS 55th International Symposium & Exhibition, Oct. 19-24

...p?abstractID=210 . TINY SYSTEMS FOR GROWING AND STUDYING CELLS "...We present microfluidic systems for cell growth... [and] for quantitative microinjection of macromolecules and nanoparticles into living cells..." See: http://www.avssymposium.org/paper.asp?abstractID=31 . TUNABLE MICROEDDIES TRA...

Penn Veterinary Medicine report new strategy to create genetically-modified animals

... also demonstrates that germline transduction and germ cell transplantation in large animals provides an approach that is potentially less costly than microinjection and cloning, the traditional methods used to generate transgenic large animal models for biomedical research. Researchers used mouse germ cells har...

Imaging techniques permit scientists to follow a day -- or four -- in the life of a cell

...escently labeled, so scientists can track the glowing protein with a microscope and observe what it's doing and where it's going inside the cell. This microinjection technique is similar to those that are used to create cloned and transgenic organisms, and it can also be applied to more complex assays--including la...

'Underground' tunnels discovered as means for communication between immune system cells

...if calcium flux occurs before dendritic cells unfurl their veils. With a microinjection tip, they squirted a mixture of E. coli fragments into a culture dish, and,... dendritic cells, they found that by giving a deliberate poke with an empty microinjection tip it caused the same reaction. But why some cells responded and others di...
Microinjection in Biological Technology

Sample Preparation for Microinjection

General Comments Microinjection is the loading or transfer of a dissolved substance into a living cell. The microscopic tip of the glass microcapillary has an inner...

OMT announces a breakthrough in the development of a novel human antibody platform

...st targeted knockout rats as detailed in "Knockout Rats Produced via Embryo microinjection of Designed Zinc Finger Nucleases," published in the July 24th issue of Sc... heritable, specific and permanent modifications in a mammal using standard microinjection techniques and engineered ZFNs in early-stage embryos. With antibody s...

Laser Capture Microdissection (LCM) and Expression Profiling of Long-Range Projection Neurons

...o Alexa-fluor dyes (Molecular Probes, Cat. #C-22841, C-22842) ◊ Glass micropipettes (Drummond Wiretrol, 1-5 uL Cat. #5-000-1001) ◊ microinjection apparatus (Narishige PE-2) II. FREEZING BRAIN AND CRYOSECTIONING ◊ Tissue embedding molds (ThermoShandon, Cat. #2219) ...

Transgenic Zebrafish by Electroporation

...dy of developmentally regulated genes. The traditional method of microinjection of foreign DNA into fertilized embryos is tedious and time consu...h by electroporation has several advantages over the traditional microinjection technique. The procedure is rapid and simple, and it allows trea...

Transformation of Nematodes With the Helios Gene Gun

...esults The established mode of DNA transfer into C. elegans is microinjection of DNA into the gonadal syncytium (Stinchcomb et al., 1985; Fire... has been observed for this Biolistic DNA transfer method as for microinjection experiments (Fire, 1986), while this new strategy is less time c...

TURBO DNase: Hyperactive, Salt Tolerant DNase

... DNA templates from transcription reactions, particularly for the synthesis of RNA standards used in RT-PCR and generating RNA for microinjection and transfection experiments. Figure 1. TURBO DNase Provides Superior Elimination of DNA from in vit...

The use of TaqMaster PCR Enhancer

... that has been incorporated into their genome. The most common method of introducing recombinant DNA into the mouse genome is by microinjection of the DNA into the pronuclei of one-cell stage mouse embryos. A fraction of these embryos develop into newborn mic...

Transgenic Animals

... microinjection of linear DNA into the pronucleus (Fig. 1) ... Fig. 1 microinjection of DNA into the pronucleus ... microinjection of DNA ...

Intracytoplasmic Spermatocyte Injection (ICSI)

...rs after microinjection. For the microinjection process described, Eppendorf offers ideal tools for easing the w...mann contrast optics or differential interference contrast optics, microinjection can be effected quickly and simply. ...

Production of Full-Length, Biologically Active MEK1WT and MEK1CA

...e uses for constitutively active MEK1 CA include identifying potential substrates, making activated MAPK, screening for inhibitors and performing microinjection studies. The term mitogen-activated protein kinase/extracellular signal-activated protein kinase ( M APK/ E RK k inase, MEK) refers to two du...
Microinjection in Biological Products

Rabbit Anti-Human XAB2 (N-terminus) Polyclonal Antibody, Unconjugated from GeneTex

Description:... demonstrated that a fraction of XAB2 interacts with the transcription-coupled repair-specific proteins CSA and CSB as well as with RNA polymerase II. microinjection experiments with XAB2 antibodies resulted in the inhibition of both transcription-coupled repair and transcription. Immunogen: Peptide correspondin...
Company:GeneTex

Nanoject II, 220 VOLT from Drummond Scientific Company

Description:...mmond Scientific has a long and outstanding history in the manufacturing of microinjection apparatus. Several years ago we became aware that our 10uL positive displac... filling needle and maintenance kit. Automated Microprocessor controlled microinjection Pipet delivering precise nanoliter volumes accurately Remote control and...
Company:Drummond Scientific Company

m7G(5)ppp(5)G (Cap Analog) from Ambion

Description:...erm in vitro translation systems. Uncapped mRNAs are rapidly degraded after microinjection into cells. Thus, it is important to cap in vitro transcripts for microinjection experiments. Cap analog is also used as a highly specific inhibitor of the ...
Company:Ambion

m7G(5)ppp(5)G (Cap Analog) from Ambion

Description:...erm in vitro translation systems. Uncapped mRNAs are rapidly degraded after microinjection into cells. Thus, it is important to cap in vitro transcripts for microinjection experiments. Cap analog is also used as a highly specific inhibitor of the ...
Company:Ambion

TURBO DNase (2 U/l) from Ambion

Description:... eliminating plasmid DNA templates from transcription reactions, particularly for the synthesis of RNA standards used in RT-PCR and generating RNA for microinjection and transfection experiments. The proficiency of TURBO DNase in binding very low concentrations of DNA means that the enzyme is particularly effective...
Company:Ambion
Microinjection in Biological Definition

Molecular biology

...or animal cells. Introducing DNA into bacterial cells is called transformation , and can be effected by several methods, including electroporation , microinjection and chemically. Introducing DNA into eukaryotic cells, such as animal cells, is called transfection. Several different transfection techniques are ...
Microinjection in Biological Dictionary

Xenopus

... Xenopus . Vernacular Names: African Clawed Frogs. References ... Xenopus laevis as a model organism. Syst. Biol. 42(4):476-507. de Sá, R. O. ... microinjection of Xenopus laevis oocytes followed by thin-sectioning electron ... Part 3: Dissection of Xenopus oocytes. The next day, wash the oocytes 3 tim...

Transgenic mouse

...out of the transgenic facility to the investigators own mouse rooms. ... Transgenic Mouse . MGE core. Construct design expertise. Pronuclear microinjection ... Transfer of founder transgenic mice and littermates as controls to PI laboratory ... Jun. 24, 2002 - Emerging technologies allow researcher...
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