New research finds markers for esophageal cancer before it develops
... biomarkers that could distinguish between low-grade and high-grade dysplasia. Using state-of-the-art molecular techniques, including laser capture microdissection followed by gene expression analysis, the researchers identified a number of potential biomarkers. Resnick concludes, "Using this process, it is the f...MDS Reports Second Quarter 2008 Results
...us XT(TM) instrument for laser capture microdissection. The new Arcturus XT(TM) offers researchers improved speed, precision and flexibility for their microdissection experiments. Guidance Primarily as a result of softening demand for high-end instruments in the pharmaceutical markets and a delay in achieving ta...Theranostics Health Signs Research Collaboration Agreement
...Duke investigators access to the company's core technologies: Laser Capture microdissection (LCM) and Reverse Phase Protein Microarray (RPMA). The proprietary combinat...le, MD. Its core technology is the proprietary combination of Laser Capture microdissection (LCM) and Reverse Phase Protein Microarray (RPMA) both developed by the com...NIH Grants Exclusive License to Theranostics Health
...usive license from the National Institutes of Health (NIH) to commercialize microdissection including Laser Capture Microdissection (LCM) combined with protein analysi...through Reverse Phase Protein Microarray (RPMA) combined with Laser Capture microdissection (LCM). The technology measures the activity of a large number of biomarkers...Area Around Breast Tumor May Predict Cancer's Spread
...sue samples from 218 breast cancer patients: 43 with hereditary breast cancer and 175 with sporadic breast cancer. A technique called laser-capture microdissection was used to take individual breast cancer cells and surrounding stromal cells. Mutations in p53, in the stroma but not in the cancer, increased the...Reducing The After Effects of Tonsillectomy
...long to control bleeding during the procedure. The microdissection needle technique uses less energy to achieve the s...rounding tissue. Researchers investigated the microdissection needle technique on nearly 50 children between age...tonsillectomy was performed using the lower-energy microdissection needle. The children that underwent the...Theranostics Health Receives Green Light to Perform Clinical Testing
... a privately held company founded in 2006. Its core technology is the breakthrough Reverse Phase Protein Microarray (RPMA) combined with Laser Capture microdissection (LCM). The technology measures the activity of a large number of biomarkers, enabling pharmaceutical companies to accurately profile their drug candid...One gene links newborn neurons with those that die in diseases such as Alzheimer's
...ices of brain tissue, the researchers used a technique called laser capture microdissection to collect cells of each type. From these they purified RNA, the quantity o... which corresponds to the activity of the particular gene producing it. The microdissection technique uses a low-power laser to melt a small circle of film into the ti...Laser Capture Microdissection of Cells Labeled with Enhanced Green Fluorescent Protein
Vasker Bhattacherjee, Partha Mukhopadhyay, Saurabh Singh, Robert M. Greene and M. Michele Pisano, University of Louisville Birth Defects Center, Department of Molecular, Cellular and Craniofacial Biology, Louisville, KY 40202 Abstract This application note describes a Las...Laser Capture Microdissection of muscle fiber populations and expression analysis by RT-PCR
Sven Fraterman and Neal Rubinstein, Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia Abstract To locate gene products in distinct muscle fiber populations of different muscle allotypes, a novel protocol was establi...Laser Capture Microdissection (LCM) and Expression Profiling of Long-Range Projection Neurons
(Anthony Lombardino, Rockefeller University) Abstract Brain tissue is notoriously heterogeneous, and accurate analysis of neural gene expression requires procurement of specific cell types. In this application note a technique is described for using Laser Capture Microd...Working With Laser Capture Microdissection Samples
Laser Capture Microdissection (LCM) is a method for obtaining pure populations of cells from heterogeneous samples. LCM permits the selection and capture of cells, cell aggregates, and discrete morphological structures from thin tis...Laser microdissection and nucleic acid purification - a Leica - QIAGEN cooperation
Stefanie Schrer, Werner Wittke,* and Christian Kupfer QIAGEN GmbH, Hilden, Germany * Leica Microsystems, Wetzlar, Germany Laser microdissection (LMD) provides a powerful t...Isolate and Analyze Total RNA from Cells Harvested by Laser Capture Microdissection
StrataPrep total RNA microprep kit for very small samples Karen Dolter Sylvia Norman Jeff Braman Stratagene Isolating total RNA from laser capture microd...Danong Chen appointed CEO of Theranostics Health
... a privately held company founded in 2006. Its core technology is the breakthrough Reverse Phase Protein Microarray (RPMA) combined with Laser Capture microdissection (LCM). The technology measures the activity of a large number of biomarkers, enabling pharmaceutical companies to accurately profile their drug candid...Eppendorf MicroDissector from Eppendorf North America
Description:... The Piezo Power microdissection (PPMD) system is designed for rapid isolation of single cells or small cell areas...CapSure Macro LCM Caps - Bulk Pack from Arcturus, now part of Molecular Devices
Description:... Precision-designed for Optimal microdissection CapSure HS and CapSure Macro LCM Caps enable th...cap surface. Using the PixCell, AutoPix or Veritas microdissection Systems, an infrared laser pulses through the top ...ssue or cell samplecreating a gentle, non-damaging microdissection that preserves the integrity of the captured mater...CapSure Macro LCM Caps from Arcturus, now part of Molecular Devices
Description:... Precision-designed for Optimal microdissection CapSure HS and CapSure Macro LCM Caps enable th...cap surface. Using the PixCell, AutoPix or Veritas microdissection Systems, an infrared laser pulses through the top ...ssue or cell samplecreating a gentle, non-damaging microdissection that preserves the integrity of the captured mater...Imaging Mass Spectrometry for Small Molecule Localization from Protein Discovery, Inc.
Description:...ound. Imaging mass spectrometry enables cell type specific analysis without microdissection or homogenization and differentiates between drug compounds and their metab...drug compound from metabolites Preserves spatial information No microdissection No homogenization ...