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Microcephaly in Medical News

BRIT1 allows DNA repair teams access to damaged sites

...imary microcephaly, in which the brain develops to only one third of normal size. The team showed that in experiments using cells derived from primary microcephaly patients that BRIT1 dysfunction may specifically contribute to development of the neurological disease by failing to bind to SWI-SNF to relax chromati...
Microcephaly in Medical Dictionary

Microcephaly

Microcephaly is a neurodevelopmental disorder in which the circumference of the head is more than two standard deviations smaller than average for the person's age and sex. Microcephaly may be congenital or it may develop in... Microcephaly information sheet compiled by the National...
Microcephaly in Biological News

New molecular insight into vertebrate brain development

...PPO path may bring insights to human brain malformations. There are a number of brain size defects for which we are considering a follow up, including microcephaly and Autism, where the overall brain size is affected but structures retain the proportionality. The function of the HIPPO pathway also has implication...

Human brain is still evolving

...o genes - Microcephalin and "abnormal spindle-like microcephaly associated" (ASPM) - across different human popula... genes can render the gene nonfunctional and cause microcephaly - a clinical syndrome in which the brain develops ... two genes would make it a trend. Here we have two microcephaly genes that show evidence of selection in the evolu...
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