OROS(R) Methylphenidate in Adults with ADHD: New Insights

Final results of sub-analyses of dose-titration study and long-term, open-label study presented today WASHINGTON, May 7 /PRNewswire/ -- Although once considered to be a disorder only seen in children, Attention Deficit Hyperactivity Disorder (ADHD) is now known to be a con...

Consumer Reports to Parents: Think Twice About Free Prescription ADHD Drug Samples for Your Children

...n the spot. ADHD Drugs May Only Work for a Few Years And there is another hitch: a recent study shows that at least one ADHD stimulant drug, methylphenidate (Ritalin), may only work for a few years. There is little evidence proving a clear benefit beyond that. Long term studies have not been done on other ...

ADHD Drugs Linked to Sudden Death in Kids

...ny as 2.5 million children in the United States take ADHD stimulant medications, such as amphetamine, dextroamphetamine (Adderall), methamphetamine or methylphenidate (Ritalin), according to an editorial in the same issue. In the early 1990s, several reports of sudden, unexplained death in children taking these m...

San Diego Psychiatrist Scott Irwin Honored With National Recognition

...ssfully secured a $154,000 career development grant from the National Palliative Care Research Center (NPCRC). The award supports Dr. Irwin's study of methylphenidate (Ritalin) for the treatment of depression in hospice patients. "This award was granted in an exceedingly competitive environment where there is ...

$1.5 million awarded for palliative care research to improve care of seriously ill patients

...Irwin will assess the feasibility of conducting a randomized, controlled, safety and efficacy trial of rapidly treating major depressive episodes with methylphenidate monotherapy in patients receiving hospice care. This trial will lay the groundwork for future multi-site randomized controlled trials in patients rece...

District Court Decision Received in CONCERTA(R) Patent Case

...y generic versions of CONCERTA(R) extended-release methylphenidate tablets are both bioequivalent and clinically equi...ld not be taken by patients who have: allergies to methylphenidate or other ingredients in CONCERTA; significant anxi...ars of age should not take CONCERTA. Abuse of methylphenidate may lead to dependence. Tell your healthcare profe...

Non-safety-related voluntary market withdrawal of a limited portion of DAYTRANA(R) (methylphenidate transdermal system) patches announced

...problems, such as chest pain or fainting. Daytrana should not be used if the child has: significant anxiety, tension, or agitation; allergies to methylphenidate or other ingredients of Daytrana; glaucoma; discontinued in the last 14 days or is taking a monoamine oxidase inhibitor (MAOI); tics, or family histor...

Narcolepsy Drug Might Be Addictive

...th schizophrenia and attention-deficit/hyperactivity disorder (ADHD). This new finding suggests that the drug may work more like stimulants such as methylphenidate (Ritalin) and amphetamine than previously thought. These drugs, used to treat ADHD, increase dopamine levels. And now people are also buying it wit...

Mouse Study Suggests ADHD Drug Might Be Addictive

...addictive properties of methylphenidate, and imply that chronic exposure of methylphenidate in humans may lead to addiction," he said. Kim noted that the researcher...igh doses or injected, Ritalin could become addictive, he said. "Indeed, methylphenidate is widely abused for improving concentration and enhancing performance, or ...

CCHR Says New Mental Health Study on College Age Students Misleading

...) depressants, "such as barbiturates and benzodiazepines (Klonopin, Xanax)," and stimulants, "such as dextroamphetamine (Dexedrine) and methylphenidate (Concerta, Ritalin)." Moreover, the website says approximately 50 million Americans aged 12 or older reported non-medical use of any psychotherap...

Methylphenidate in Medical Technology

Addrenex Pharmaceuticals Reports Positive Results in Second Phase 3 Study of ADHD Medication

...stimulants," said Moise Khayrallah, Ph.D., CEO of Addrenex Pharmaceuticals. "In children who are not receiving optimal benefit from stimulants such as methylphenidate or amphetamine, Clonicel may provide greater relief than using a stimulant medication alone." The current study of 200 children with ADHD is the ...

Head-to-Head Study Demonstrates Focalin(R) XR Offers Faster and Better Symptom Control than Concerta(R)1 in Early Part of ADHD Patients' Day

...-methylphenidate. Therefore, only half the dose of methylphenidate is required. Concerta is a d,l-methylphenidate. ...en with ADHD with 6-12 years of age, stabilized on methylphenidate and randomized to different treatment sequences fo...ymptoms; in patients known to be hypersensitive to methylphenidate or other components of the product; in patients wi...

New Analysis in Boys and Girls Shows the ADHD Patch, DAYTRANA(TM) (methylphenidate transdermal system), Offered ADHD Symptom Control for 12 Months

...art problems, such as chest pain or fainting. DAYTRANA should not be used if the child has: significant anxiety, tension, or agitation; allergies to methylphenidate or other ingredients of DAYTRANA; glaucoma; discontinued in the last 14 days or is taking a monoamine oxidase inhibitor (MAOI); tics, or family histor...

Shire to Present Additional Scientific Data on ADHD Treatment Portfolio at American Psychiatric Association Annual Meeting

...mmunity will find the lisdexamfetamine dimesylate, methylphenidate transdermal system and guanfacine extended release...ts with ADHD APA Oral Presentation Session # 28 methylphenidate Transdermal System: May 7, 2008; 12:00 p.m. ET Long-Term Treatment Effects of the methylphenidate Transdermal System in Boys and Girls with ADHD A...

New Study of Concerta(R) Showed Significant Improvement of ADHD Symptom Management in Adults Compared to Placebo

...ficant anxiety, tension or agitation; allergies to methylphenidate or other ingredients in CONCERTA(R); glaucoma; Tou...or family history of Tourette's syndrome. Abuse of methylphenidate may lead to dependence. Tell your health care prof...ren. McNeil Pediatrics markets CONCERTA(R) OROS(R) methylphenidate HCL for treatment of children and adolescents with...

Long-Term 12-Month Safety Data Presented on ADHD Patch DAYTRANA(TM) (methylphenidate transdermal system)

...0 October 25, 2007; 11:00 a.m. EDT Long-Term (Up To 12 Months) Use of the methylphenidate Transdermal System Frank A. Lopez, M.D., Oscar G. Bukstein, M.D., Robert L.... if the child has: significant anxiety, tension, or agitation; allergies to methylphenidate or other ingredients of Daytrana; glaucoma; discontinued in the last 14 day...

New Data Suggests Less Abuse-Related Effects For OROS Methylphenidate

...tion highlighted findings that long-acting OROS(R) methylphenidate had fewer reports of abuse and lower abuse-related...ations for ADHD. The unique, long-acting OROS(R) methylphenidate formulation initially releases the drug, followed ...mpared with an immediate-release, or short-acting, methylphenidate formulation. The data presented Tuesday from two s...

New Data Focuses on Abuse of Stimulant Medication

...tion highlighted findings that long-acting OROS(r) methylphenidate had fewer reports of abuse and lower abuse-related...ations for ADHD. The unique, long-acting OROS(r) methylphenidate formulation initially releases the drug, followed ...mpared with an immediate-release, or short-acting, methylphenidate formulation. The data presented on Tuesday from tw...

12-Month Study Demonstrated Tolerability and Efficacy of DAYTRANA (methylphenidate transdermal system)

...ll of the children in this open-label, flexible-dose trial participated in one of four trials in which the children previously received DAYTRANA, OROS methylphenidate or a placebo. All of the children previously used DAYTRANA for at least a minimum of three days and a maximum of 37 months. While this study evaluated...

Daytrana (methylphenidate transdermal system) Provides Significant Effectiveness in ADHD Symptom Relief in Both Boys and Girls

...art problems, such as chest pain or fainting. Daytrana should not be used if the child has: significant anxiety, tension, or agitation; allergies to methylphenidate or other ingredients of Daytrana; glaucoma; discontinued in the last 14 days or is taking a monoamine oxidase inhibitor (MAOI); tics, or family histor...

Methylphenidate in Medical Dictionary

Ritalin

... methylphenidate (MPH) is the most commonly prescribed psychostimul...yle destination... Stimulant ADHD Medications: methylphenidate and Amphetamines information at the ... methylphenidate (e.g., Ritalin and Concerta—a formulation that r...

Behavior

... Behavior ... Since "Diet, ADHD, and Behavior " was. published in 1999, several ... adverse effects on behavior and on possible. problems with methylphenidate (Ritalin), the ... ... for school personnel, parents, and other professionals concerning the full range of behavior problems and challenges di...

Methylphenidate in Biological News

Studies examine genetic determinants of ADHD

...ing ADHD and whether these initial findings can be confirmed. Another study, also led by Dr. Faraone, is the first genome-wide study of response to methylphenidate in ADHD children. Dr. Faraone and his colleagues, examined genetic markers across the entire human genome to search for genes that may someday be used...

Hopkins scientists show hallucinogen in mushrooms creates universal 'mystical' experience

...d. Each of thirty of the subjects attended two separate 8-hour drug sessions, at two month intervals. On one they received psilocybin, on another, methylphenidate (Ritalin), the active placebo. In designing the study, researchers had to overcome or at least, greatly minimize two hurdles: the risk of adverse...

Ritalin packs punch by elevating norepinephrine, suppressing nerve signal transmissions

... methylphenidate (Ritalin) elevates norepinephrine levels in the br...ate," Waterhouse said. "If we can show exactly how methylphenidate works, we may be able to produce even more effecti...aking the drug who do not suffer from ADHD or ADD. methylphenidate use is on the rise among college students who soli...

Methylphenidate in Biological Technology

FDA Approves CONCERTA(R) (methylphenidate HCI) Extended-release Tablets for Treatment of ADHD (Attention Deficit Hyperactivity Disorder) in Adults

...noamine oxidase inhibitor (MAOI); esophagus, stomach, or intestinal narrowing. Children under six years of age should not take CONCERTA(R). Abuse of methylphenidate may lead to dependence. Tell your healthcare professional if you or your child has had problems with alcohol or drugs; has had any heart problems, hea...

Non-Safety-Related Voluntary Recall of a Limited Portion of DAYTRANA(TM) (Methylphenidate Transdermal System) Patches Announced

...art problems, such as chest pain or fainting. Daytrana should not be used if the child has: significant anxiety, tension, or agitation; allergies to methylphenidate or other ingredients of Daytrana; glaucoma; discontinued in the last 14 days or is taking a monoamine oxidase inhibitor (MAOI); tics, or family histor...

Separation and Quantitation of R and S Enantiomers using Normal Phase Chromatography on an API 3000 LC/MS/MS System

...gs include the antidepressant fluoxetine (Prozac), methylphenidate (Ritalin)used to treat attention deficit disorder,...pared using a simple protein precipitation whereas methylphenidate required a liquidliquid extraction. ...e R and S entantiomers of each drug. Verapamil and methylphenidate showed excellent response and linearity over the c...