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Methylenetetrahydrofolate in Biological News

SNPs affect folate metabolism in study of Puerto-Rican adults

...on, four SNPs in two genes involved in folate metabolism previously associated with altered blood folate and homocysteine concentrations were studied: methylenetetrahydrofolate reductase (MTHFR) and methionine synthase (MTR). SNPs are variations in the sequence of nucleotides, or building blocks, that make up genes. Human...

MUHC researchers make cancer target breakthrough

..., the researchers document a reduction in the growth of both colon and lung cancer tumors with inhibition of the gene. The new target gene is called methylenetetrahydrofolate reductase, or MTHFR. Researchers were able to inhibit the function of the gene by creating antisense--an exact opposite of a tiny section of the MTHFR...
Methylenetetrahydrofolate in Biological Technology

Detect Single Nucleotide Sequence Changes with Mx4000 Molecular Beacon Allelic Discrimination Kits

... thrombosis (Table 1). The MTHFR (C677T) allelic discrimination kit is used to detect a common point mutation in the human methylenetetrahydrofolate reductase gene. This mutation has been shown to be an important genetic risk factor for vascular disease and coronary heart dise...
Methylenetetrahydrofolate in Biological Products

Rabbit Anti-Human MTHFD1 Polyclonal Antibody, Unconjugated from Atlas Antibodies

Description:... C-1-tetrahydrofolate synthase, cytoplasmic (C1-THF synthase) [Includes: methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate synthetase (EC 6.3.4.3)]. [Source:Uniprot/SWI...
Company:Atlas Antibodies
Methylenetetrahydrofolate in Biological Dictionary

Polymorphisms

... Nucleotide Polymorphisms - SNPs - SNP genotyping information and resources available for pharmacogenomics - Building on the Human Genome Project methylenetetrahydrofolate reductase (MTHFR) is 'a critical enzyme in both folate and homocysteine metabolism,' according to Ueland (LOCUS for Homocysteine and ... ...
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