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Mesenchymal in Medical News

Stem Cells Used for 'Biological Pacemaker'

... is to create a biological pacemaker." Brown fat tissue is a source of mesenchymal stem cells, which previous studies have shown can develop into many differe... own pacemaker-like cells. "Our findings suggest that brown-fat-derived mesenchymal stem cells…may become a useful cell source for antiarrhythmic therapy,...

Study finds survival rates from gastrointestinal tumors improving among African-Americans

...performed using the Surveillance, Epidemiology and End Results (SEER) database that identified 3,795 patients diagnosed with GIST and other intestinal mesenchymal tumors between1992 to 2005. Patient demographics showed 72.2 percent Caucasians, 15.6 percent African Americans, and 9.1 percent Hispanics. Survival w...

Fate Therapeutics to Present Data on Stimulation of Osteogenic Activity Using Small Molecule Modulators of Wnt Pathway

...ected Wnt activators induce the differentiation of mesenchymal stem cells to mature, bone-forming osteoblasts. T...plying our knowledge of adult stem cell biology to mesenchymal stem cell populations, we have identified osteogen...es. Naturally-occurring adult stem cells, such as mesenchymal stem cells, can differentiate into a variety of ce...

Fate Therapeutics Granted Exclusive License By The Regents of the University of California to Stem Cell Modulators for Osteo-Regeneration

...cells found in almost all tissues or organs in the body and are primarily responsible for maintaining and repairing their native tissue. For example, mesenchymal stem cells are multipotent cells that can differentiate into a variety of cell types, including osteoblasts, chondrocytes, myocytes and adipocytes. D...

Hysterectomies Could Be Source of Stem Cells

...versity of Sao Paulo in Brazil found that human fallopian tubes are rich in mesenchymal stem cells. The team isolated and grew these cells in a laboratory and diff... Past studies have also shown success with isolating and differentiating mesenchymal stem cells harvested from umbilical cords, dental pulp and body fat. To...

Stem Cell Study Offers Hope for Targeting Tumors

...ut 38 percent of metastasized lung tumors in rodents. The study results combined findings from two previous areas of research: one that found that mesenchymal stem cells (MSCs), which come from bone marrow, can work as messengers to tumors cells, and another that found TRAIL effective at killing cancer while...

World Anti-Aging Congress 2009 Defies Global Economic Downturn, Demonstrating Strength of Anti-Aging Medical Movement

....D., a physician based in the Boulder, Colorado USA area, presented the latest on "Stem Cell Therapeutics: Tissue Regeneration,"highlighting mesenchymal stem cells for musculoskeletal tissue repair The worldwide anti-aging marketplace is estimated at $96.89 Billion in 2008. Growing at a compounded...

Former Executive at Genzyme Corp. and Osiris Therapeutics, Inc. to Head Business Advisory Board at Rx for Africa, Inc.

...s currently exceed $600 million. Genzyme's market cap exceeds $18 billion. Mr. Pursley subsequently became CEO of Osiris Therapeutics, Inc., a leading mesenchymal stem cell company, which recently announced a major corporate alliance with Genzyme. In 1999, Mr. Pursley joined Transkaryotic Therapeutics as Se...

Patient Movement Forms in Opposition to FDA Position that the Patient's Own Stem Cells are Drugs

... avoid the need for more invasive orthopedic surgery. Dr. Centeno has published numerous medical research papers on the clinical application of adult mesenchymal stem cells. For more information, visit www.stemcelldocs.org . MEDIA CONTACT: Holly Hamann media (at) stemcelldocs (dot) org # # # Read...

Mayo researchers discover mechanism of cell type-specific signaling in tumor development

...pment, is activated in one type of tissue but not another. PAK2 is a downstream component of transforming growth factor beta (TGF-β) signaling in mesenchymal cells those that make up connective tissues in the body, as well as blood and lymphatic vessels. However, TGF-β is unable to activate PAK2 in ep...
Mesenchymal in Medical Technology

Three Surgeons in East Texas Are Successfully Integrating a Novel Stem Cell Procedure for Spine Surgeries

... patient. This is minimally invasive, efficient, safe and effective. The concentrations of endothelial progenitor cells, hematopoietic stem cells, and mesenchymal stem cells have adhesion properties that ensure the cells remain localized where we need them to promote tissue growth and healing. Surprisingly, the ...

Cardium Reports on Applicability of Corgentin to Stem Cell Therapies: Independent Studies Indicate that Ad5IGF-1 Potentiates Stem Cells to Improve Cardiac Function After Heart Attack

...ity of Cincinnati entitled IGF-1--Overexpressing mesenchymal Stem Cells Accelerate Bone Marrow Stem Cell Mobili...(11): 1300-1308). The investigators reported that mesenchymal stem cells (MSCs) can be potentiated by introducin.../CARDIUMLOGO ) "Recent findings indicate that mesenchymal stem cells, which are processed ex vivo before rei...

New Study Using Combination of Bioengineered Skin and Stem Cells Shows Promise in Treatment of Non-Healing Wounds

...ention was to grow a particular type of stem cells in the laboratory called mesenchymal stem cells, which are cells that can create other cell types, including tho...case, the two substances, highly diluted, were used to deliver the cultured mesenchymal stem cells to the wounds of scleroderma patients in a fine transparent spra...

Scientists Discover Why Teeth Form in a Single Row

...mmals can develop teeth (the "tooth morphogenetic field") is shaped and restricted by the effect of Osr2 on the expression of the Bmp4 gene within the mesenchymal cell layer. Jiang's team has shown not only that removing the Osr2 gene results in extra teeth outside of the normal row, but also that Osr2 is expres...

Gene Marker May Improve Odds of Stem Cell Therapies for Disease

... PHILADELPHIA, Jan. 9 /PRNewswire-USNewswire/ -- A single tumor-suppressor gene may provide a unique marker for senescence in mesenchymal stem cells (MSCs) in vitro, while also playing a role in moving MSCs into senescence, researchers at the Human Health Foundation and the Sbarro Instit...

NeoStem Reports Positive Stem Cell Industry Research Trends From The Journal of the American Medical Association and Third Annual Stem Cell Summit

...isorders. The article also highlighted that the vast majority of human stem cell trials have focused on clinical applications for hematopoietic and/or mesenchymal stem cells, both of which may be obtained from peripheral blood, bone marrow, or umbilical cord blood and placenta. The National Institutes of Healt...

New Non-Surgical Stem-Cell Procedure to Relieve Chronic Tendon Problems

...mail Regenexx@rsihealth.net. All costs directly related to the study will be covered by the company. The study involves harvesting the patient's own mesenchymal stem cells, growing them in a culture using the company's patent pending procedure, and then injecting these culture expanded cells into an area in ne...

Derma Sciences to Enter Phase II Development of Wound Healing Product That May Use Body's Own Naturally Occurring Stem Cells

...ng powers may work by promoting the recruitment of mesenchymal stem cells to sites of tissue injury. mesenchymal stem cells are integral to the creation of several...te of tissue injury may promote the recruitment of mesenchymal stem cells in numbers that support the rapid heali...

Leukemic Cells Find Safe Haven in Bone Marrow

... St. Jude study shows mesenchymal cells in bone marrow supply leukemic cells with th...s Research Hospital. The researchers showed that mesenchymal cells in the bone marrow create a protective niche...agine should be tested to see if they also prevent mesenchymal cells from making this amino acid. In addition, th...

Heart Attack Patients Treated With Novel Stem Cell Therapy Experience Significant Improvement in Heart and Lung Function

...promising is that these stem cells can be used without tissue typing and do not trigger an immune response, and are available for every patient. The mesenchymal stem cells (MSC) are found in the adult bone marrow and have the potential to develop into mature heart cells and new blood vessels. The MSC cells are...
Mesenchymal in Biological News

Intraspinal implant of mesenchymal stem cells may not heal the demyelinated spinal cord

Tampa, Fla. (Nov. 12, 2008) Multiple sclerosis is a disease caused by the loss of the myelinated sheath surrounding the nerve fibers of the spinal cord. Therapeutic hope for curing multiple sclerosis and other demyelinating diseases has included the possibility that stem cell transplants could he...

Stem cell research: From molecular physiology to therapeutic applications

... group has taken stem cell therapy into phase II clinical trials in China, and is the leading runner in stem cell therapeutics. They have identified a mesenchymal stem cell (MSC) population from human fetal bone marrow and found that these cells could differentiate not only into osteogenic, adipogenic and endoth...

NIH funds work at WPI on regenerating heart tissue and preventing urinary tract infections

...h cranberry juice. The goal is to develop a new therapy for UTIs that does not rely on antibiotics. Gaudette's lab explores the potential for human mesenchymal stem cells (hMSCs), which come from the bone marrow, to regenerate cardiac tissue, thereby helping a damaged heart beat more effectively. Heart attack...

Adult bone marrow stem cells injected into skeletal muscle can repair heart tissue

...ntract, by up to 50 percent. "This work demonstrates a novel non-invasive mesenchymal stem cell (MSC) therapeutic regimen for heart failure based on an intramusc..., UB associate professor of biochemistry and senior author on the paper. mesenchymal stem cells are found in the bone marrow and can differentiate into a variet...

MIT: New tissue scaffold regrows cartilage and bone

...in Europe. The scaffold has two layers, one that mimics bone and one that mimics cartilage. When implanted into a joint, the scaffold can stimulate mesenchymal stem cells in the bone marrow to produce new bone and cartilage. The technology is currently limited to small defects, using scaffolds roughly 8 mm in...

Scientists discover why teeth form in a single row

...mmals can develop teeth (the "tooth morphogenetic field") is shaped and restricted by the effect of Osr2 on the expression of the Bmp4 gene within the mesenchymal cell layer. Jiang's team has shown not only that removing the Osr2 gene results in extra teeth outside of the normal row, but also that Osr2 is expres...

Columbia University scientist devises new way to more rapidly generate bone tissue

... researchers has co-transplanted hematopoietic and mesenchymal stem/progenitor cells to promote the regeneration ...ries of Science, takes a new approach: rarely have mesenchymal and hematopoietic cells been delivered in combinat...r. Mao and colleagues demonstrated that when human mesenchymal stem/progenitor cells were seeded in micropores of...

New 'control knobs' for stem cells identified

... "Membrane Potential Controls Adipogenic and Osteogenic Differentiation of mesenchymal Stem Cells" in the November 17, 2008, issue of PLoS ONE ( http://www.plo... changes in membrane potential (voltage across the membrane) shown by human mesenchymal stem cells (hMSCs) obtained from donor bone marrow as the hMSCs were differ...

Case Western Reserve receives Ellison Medical Foundation New Scholar in Aging award

...Novel Microenvironmental Technology to Rescue the Chondrogenic Potential of mesenchymal Stem Cells from Aged Individuals for Autologous Cartilage Tissue Engineerin...this possible." One cell population of particular interest to Alsberg is mesenchymal stem cells (MSCs). They have the remarkable ability to change into differen...

Simple chemical procedure augments therapeutic potential of stem cells

...er problems. They're not limited to sticking SLeX on cells." The team worked with human cells extracted from the bone marrow. The cultures included mesenchymal stem cells (MSCs), which can form fat cells, cartilage, bone, tendon and ligaments, muscle cells, and even nerve cells. When injected into the bloodst...
Mesenchymal in Biological Technology

STEMCELL Technologies Introduces a New Animal Component-Free, Serum-Free Medium for Culturing Human Mesenchymal Stem Cells

STEMCELL Technologies, Inc. today announced the release of MesenCult®-ACF Medium , the first defined, animal component-free (ACF) and serum-free medium for culturing human mesenchymal stem cells (MSCs). Vancouver, B.C. (PRWEB) April 28, 2009 -- STEMCELL Technol...

ArunA Biomedical Announces Commercial Release of its Human Embryonic Stem Cell Derived Mesenchymal Cells

ATHENS, Ga., March 27 /PRNewswire/ -- ArunA Biomedical, Inc., announced today that it will make its CELL-EZ(TM) brand hMC(TM) human mesenchymal progenitor cells commercially available to the research community in mid 2009. Derived from pluripotent human embryonic stem cells, ArunA's hMC lines wil...

ArunA Biomedical Announces Exclusive Worldwide Technology Licensing Agreement to Commercialize Human Embryonic Stem Cell Derived Mesenchymal Cells

ATHENS, Georgia, Aug. 19 /PRNewswire/ -- ArunA Biomedical, Inc., a leader in human embryonic stem cell derived products, announced today that it has entered into an exclusive worldwide technology licensing agreement with the University of Georgia Research Foundation that will enable the compan...

Cardium Announces New Orthobiologics Product Initiative Extending Gene Activated Matrix Technology to Deliver Bone Growth Factors

...ective. ( Click here to see x-ray images from TRC pre-clinical research relating to chBMP-4 ). BMPs play a key role in the transformation of mesenchymal cells into bone and naturally recruit stem cells from the surrounding tissue to initiate the bone formation cascade. BMPs have been the focus of many...

Fallopian tubes offer new stem cell source

...st time that human fallopian tubes are abundant in mesenchymal stem cells which have the potential of becoming a ... cell types. It has previously been shown that mesenchymal stem cells obtained from umbilical cords, dental p...solate and assess the differentiation potential of mesenchymal stem cells from discarded human fallopian tubes. I...

Physician's Organization Makes History by Publishing U.S.'s First Adult Stem Cell Guidelines (ASCTA Drives Safe Stem Cell Practices)

... avoid the need for more invasive orthopedic surgery. Dr. Centeno has published numerous medical research papers on the clinical application of adult mesenchymal stem cells. More information on Dr. Centeno can be found at here . About Zannos Grekos, M.D. Zannos Grekos, MD, FAAC is an invasive cardiologis...

NeoStem Obtains Exclusive License to Innovative Stem Cell Procedure Treating Musculoskeletal Diseases

...m cells from an individual's bone marrow, isolates mesenchymal stem cells (which can grow into bone, tendon, musc.... Centeno will continue to assist NeoStem in using mesenchymal stem cell isolation and transplantation methods ab...e will also train NeoStem personnel in Colorado in mesenchymal stem cell isolation, preparation and transplantati...

NeoStem Obtains Exclusive Worldwide License for Innovative Stem Cell Technology and Applications to Heal Chronic Wounds

...Healing Society, the leading scientific organization focused on this specialty. Dr. Falanga's stem cell product under development, Primcel, is a mesenchymal stem cell (MSC) product. Early clinical studies indicate that Primcel can be used to accelerate or jump start healing of chronic wounds. Dr. Falanga...

Heart Hospital of Austin First Site in World to Test Efficacy of New Adult Stem Cell Therapy to Treat Damaged Heart Tissue in Phase II Trial

... Prochymal(R) is being evaluated for its ability to treat heart damage caused by a heart attack. The active ingredient in the new treatment is adult mesenchymal Stem Cells (MSCs). The cells in the drug are from normal, healthy adult volunteer donors and are not from a fetus, embryo or animal. MSCs have the a...

Renowned Stem Cell Researcher Files Study Results With Stemedica

...exciting and profound. First of all, the results reaffirm our assumptions about the short and long term safety of adult stem cells in general and our mesenchymal bone marrow stem cell line in particular. Secondarily, study results clearly showcase the regenerative nature of adult stem cell therapy in compariso...
Mesenchymal in Biological Products

Human Mesenchymal Stem Cell Functional Identification Kit from R&D Systems

Description: Request Info...
Company:R&D Systems

Pancreatic Cell Cryopreservation Medium from CHEMICON

Description:...um (2X) is intended for the cryopreservation of LT2 Immortalized Pancreatic mesenchymal Cells (SCR013) and VIT1 Primary Pancreatic mesenchymal Cells (SCR014)....
Company:CHEMICON

UCB MSC Cell Chip-IHC from 3H Biomedical AB

Description:... Umbilical cord blood mesenchymal stem cells, For immunohistochemistry (IHC) Cell Chip with Human Umbilical Cord Blood Progenitor Cells...
Company:3H Biomedical AB

Human BMP-5 ELISA development Kit, DuoSet Economy Pack from R&D Systems

Description:... and morphogenesis of various tissues and organs. BMPs regulate the growth, differentiation, chemotaxis and apoptosis of various cell types, including mesenchymal cells, epithelial cells, hematopoietic cells and neuronal cells. Similar to other TGF-beta family proteins, BMPs are highly conserved across animal sp...
Company:R&D Systems

Treated Tissue Culture 245 mm x 245 mm Dish, 4/pk from StemCell Technologies, Inc.

Description:... Recommended for supporting the growth of anchorage-dependent cells including human and mouse stromal cells, mesenchymal cells and cell lines....
Company:StemCell Technologies, Inc.
Mesenchymal in Biological Definition

Stem cell

...from liposuction. This source of cells seems to be similar in many ways to mesenchymal stem cells (MSCs) derived from bone marrow, except that it is possible to i...itically ill heart patients, researchers in Vienna have successfully used mesenchymal stem cells to regenerate healthy new heart tissue. The adult stem cells we...

Tumor

...le ducts epithelium: cholangiocellular adenoma , cholangiocellular carcinoma melanocytes: melanocytic nevus , malignant melanoma Tumors of mesenchymal origin: connective tissue: fibroma , fibrosarcoma myxoma , myxosarcoma chondroma , chondrosarcoma osteoma , osteosarcoma (ost...
Mesenchymal in Biological Dictionary

Typhlosole

...at blog ... typhlosole . Typhoid. typhoid fever. Typhoid mary. Typhoo put the T in Britain, and you ... The typhlosole emanates from a lamina of mesenchymal cells located between the ... The typhlosole primordium is later embedded in the dorsal wall of intestine ... Transcripts from Lymphocyte...

Sterile cell

...mother cells abort prior to completing meiosis (Figs. ... cells varied significantly between fertile and sterile plants. ... S1569 Stemline mesenchymal Stem Cell Expansion Medium Without L-glutamine, liquid, sterile -filtered, cell culture tested Developed to promote the optimal expansion ... ...

Stem

...cellence. ODE Curriculum. ODE Academic Content Standards ... Adult stem cells, obtained from developed tissue (regardless of the age of the ... mesenchymal stem cells can produce such tissue types as bone, cartilage, ... The question of stem cells is currently the dominant subject in the de...

Stem cell

...What are the potential uses of human stem cells ? ... Adult stem cells , obtained from developed tissue (regardless of the age of the ... mesenchymal stem cells can produce such tissue types as bone, cartilage, ... ...

Myotome

...e development (MGI Ref ID J:29279) ... ... embryo has normal looking somites, including a normal myotome , but no myoblasts. ... cells become mesenchymal again, first the scleratome, and later the myotome . ... ...

Blastema

...he proximal components of the nephron from the ... Blastema ' carries hidden implications, some of which may be quite problematic. ... But the mesenchymal cells of the blastema produce cartilages and, in time, the ... called Blastema , which adds fast repairability in a portable way ... pairable ...
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