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Mastocytosis in Medical News

Patient with rare disorder responds to cancer drug

... marrow cancer characterized by an overabundance of basophils. Systemic mastocytosis often results from a mutation in the gene that codes for the KIT receptor f...e fusion protein in patients who present with clinical findings of systemic mastocytosis and chronic basophilic leukemia may enable doctors to successfully treat th...

Abnormal immune cells may cause unprovoked anaphylaxis

...tic trigger related to that seen in mastocytosis. It is known that systemic mastocytosis in adults often results from a mutation in the Kit receptor found on the su...he NIH Clinical Center, the researchers examined 48 patients diagnosed with mastocytosis with or without associated anaphylaxis, 12 patients with idiopathic anaphyl...
Mastocytosis in Medical Technology

Video: Data on More Than 15 Novartis Oncology Compounds at ASCO Highlight Progress Toward Targeted Therapies for Diverse Tumor Types

...ersible with the administration of systemic steroids, circulatory support measures, and temporarily withholding imatinib. MDS/MPD disease and systemic mastocytosis may be associated with high eosinophil levels. Performance of an echocardiogram and determination of serum troponin should therefore be considered in ...
Mastocytosis in Medical Dictionary

Mastocytosis

Mastocytosis is a group of rare disorders of both children and adults caused by the presence of too many mast cells (mastocytes) and CD34+ mast cell precursors in a person's body. Mastocytosis is the term for a group of disorders caused by too many ... Systemic mastocytosis is cause...
Mastocytosis in Biological Dictionary

Cell growth

...mber ... Original Article from The New England Journal of Medicine -- Altered Metabolism of Mast- Cell Growth Factor (c-kit Ligand) in Cutaneous mastocytosis The outermost circle represents the various cell types in C. elegans in which ... genes that promote cancer cell growth in the androgen ind...
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