Master gene controls healing of skin in fruit flies and mammals
University of California, San Diego biologists and their colleagues have discovered that the genetic system controlling the development and repair of insect cuticle--the outer layer of the body surface in insects--also controls these processes in mammalian skin, a finding that could lead to new insights into the healing of wounds and treatment of cancer. The UCSD biologists' study, publish...UT Southwestern researchers discover master switch in cell death
Researchers at UT Southwestern Medical Center have found an enzyme vital for controlling the early stages of cell death ?a beneficial and normal process when it works right, but malignant in a variety of cancers when it malfunctions. “We think t...Master regulatory gene found that guides fate of blood-producing stem cells
Researchers from the University of Pennsylvania School of Medicine found that a protein called NF-Ya activates several genes known to regulate the development of hematopoietic stem cells (HSC), or blood-producing stem cells, in bone marrow. Knowing the details of this pathway may one day lead to new treatments for such blood diseases as leukemia, as well as a better understanding of how HSCs work...Wisconsin scientists discover a master key to microbes' pathogenic lifestyles
For some microbes, the transformation from a benign lifestyle in the soil to that of a potentially deadly human pathogen is just a breath away. Inhaled into the lungs of a mammal, spores from a class of six related soil molds found around the world encounter a new, warmer environment. And as soon as they do, they rapidly shift gears and assume the guise of pathogenic yeast, causing such s...Master genetic switch found for chronic pain
In experiments with mice, researchers have found that eliminating what appears to be a master genetic switch for the development of pain-sensing neurons knocks out the animals' response to "neuropathic pain." Such pain is abnormal pain that outlasts the injury and is associated with nerve and/or central nervous system changes. The animals rendered deficient in the gene, called Runx1, also showed...Mastercycler ep gradient S thermal cycler from Eppendorf North America
Description:To keep pace with these technological advances, the challenges of tomorrow must b...Rapid-Screen Arrayed cDNA Library Panels Master Plates -Human Placenta from OriGene Technologies
Description:The Rapid-Screen cDNA Library Panels were designed for full-length gene cloning and require just three sets of PCRs to identify the desired cDNA clone. The first PCR analysis is performed in a 96-well "Master Plate," where each well contains plasmid DNA from 5,000 clones. Having identified the positive well(s) by gel electrophoresis of the reaction products, the second PCR analysis is carried out...Rapid-Screen Arrayed cDNA Library Panels Master Plates -Human Heart from OriGene Technologies
Description:The Rapid-Screen cDNA Library Panels were designed for full-length gene cloning and require just three sets of PCRs to identify the desired cDNA clone. The first PCR analysis is performed in a 96-well "Master Plate," where each well contains plasmid DNA from 5,000 clones. Having identified the positive well(s) by gel electrophoresis of the reaction products, the second PCR analysis is carried out...Rapid-Screen Arrayed cDNA Library Panels Master Plates -Mouse Testis from OriGene Technologies
Description:The Rapid-Screen cDNA Library Panels were designed for full-length gene cloning and require just three sets of PCRs to identify the desired cDNA clone. The first PCR analysis is performed in a 96-well "Master Plate," where each well contains plasmid DNA from 5,000 clones. Having identified the positive well(s) by gel electrophoresis of the reaction products, the second PCR analysis is carried out...Amplification of the amoA Gene of Nitrosococcus oceani Bacteria Using Eppendorf MasterTaq
University of Georgia, Department of Marine Sciences This application describes the use of the MasterTaq polymerase kit for improving PCR efficiency when studying functio...Amplification of Mouse cDNAs for Microarrays Using the Eppendorf MasterTaq Kit
BIOGEM, Division of Biology, University of California San Diego, La Jolla, CA 92093-0349 e-mail: ghardiman@ucsd.edu www.biogem.ucsd.edu Microarray technology, primarily advanced by Pat...cMaster RTplusPCR System for increased sensitivity and product length in RT-PCR
RT-PCR has become an essential method that allows researchers to determine the presence, structure and level of expression of an mRNA transcript in the organism, tissue or cell of interest. The basic protocol involves the synthesis of a cDNA copy of all the mRNA present in the s...Protein acts as "Master Switch" that cuts off cells' Cancer-Growth machinery
A Washington University research team headed by Shrikant Anant, PhD, is mighty excited about their new discovery that was reported in the journal, Molecular Cell. They have found a "master switch" - a protein named CUBGP2(cytidine-uridine-guanosine binding protein) - that makes cancer cells self-destruct. The findings that were published// apply only to cancer cells grown in a test tube. Human st...Researchers discover cardiac master cells
In a breakthrough finding, scientists have zeroed in on cardiac master cells that could develop into several heart tissues. //This has been discovered by different groups of researchers who have been putting their independent efforts to uncover two basic contenders. Research teams from Massachusetts General Hospital have recognized a variety of progenitor cell in mice, and have demons...Master Switches Found for Adult Blood Stem Cells
Johns Hopkins Kimmel Cancer Center scientists have found a set of "master switches" that keep adult blood-forming stem cells in their primitive state//. Unlocking the switches' code may one day enable scientists to grow new blood cells for transplant into patients with cancer and other bone marrow disorders. The scientists located the control switches not at the gene level, but farther...Master Regulatory Gene of Epithelial Stem Cells Identified
The skin’s ability to replace the tissue it sloughs off is controlled by a variety of genes. A new study from Harvard Medical School published// in the May 4 issue of Cell, however, identifies a "master regulator" of this regeneration process not only for skin, but for many epithelial tissues including breast, prostate, and urogenital tract. This master regulator of epithelial stem cells turns ou...Master Regulatory Gene of Epithelial Stem Cells Identified
The skins ability to replace the tissue it sloughs off is controlled by a variety of genes. A new study from Harvard Medical School published in the May 4 issue of Cell, however, identifies a "master regulator" of this regeneration process not only for skin, but for many epithelial tissues including breast, prostate, and urogenital tract. This master regulator of epithelial stem cells turns out...Ultramatic RX Master PHOROPTOR Refracting Instrument - Minus Cylinder Black
Description:The Ultramatic Rx Master is designed and constructed to provide years of reliable service and give the professional distinctive features that measurably improve procedures. It embodies the characteristics that doctors need and want most, including accuracy, speed, ease, patient comfort, and reliability....Ultramatic RX Master PHOROPTOR Refracting Instrument - Plus Cylinder Black
Description:The Ultramatic Rx Master is designed and constructed to provide years of reliable service and give the professional distinctive features that measurably improve procedures. It embodies the characteristics that doctors need and want most, including accuracy, speed, ease, patient comfort, and reliability....Ultramatic RX Master PHOROPTOR Refracting Instrument
Description:The Ultramatic RX Master Phoroptor the first and always thebest refracting instrument - continues to be the industry standard after nearly 80 years. Every Phoroptor has that unmistakable feel of quality. The smooth rotation of the dials. The virtual absence of play in the mechanisms. The precise, solid click of the control knobs. Constant reminders that youre using the worlds finest refractin...Ultramatic RX Master PHOROPTOR Refracting Instrument - Plus Cylinder White
Description:The Ultramatic Rx Master is designed and constructed to provide years of reliable service and give the professional distinctive features that measurably improve procedures. It embodies the characteristics that doctors need and want most, including accuracy, speed, ease, patient comfort, and reliability....