Massey Cancer Center researcher helps to identify a piece of the cancer puzzle
A structural biologist from the Virginia Commonwealth University Massey Cancer Center, in collaboration with researchers at Memorial Sloan-Kettering Cancer Center, has identified the crystal structure of a protein that plays a role in supplying nutrients to solid tumors. This identification may help researchers gain a greater understanding of the cell signaling that occurs when cancer cell...VCU Massey Cancer Center study shows enzyme linked to spread of breast cancer cells
Researchers at the Virginia Commonwealth University Massey Cancer Center have found a new signaling component that influences movement of human breast cancer cells toward epidermal growth factor. In the August issue of the Journal of Biological Chemistry, researchers showed that epidermal growth factor, which plays a critical role in breast cancer progression, stimulates sphingosine kinase...VCU Massey Cancer Center researchers identify a new class of anti-cancer drugs based on platinum
Researchers at Virginia Commonwealth University's Massey Cancer Center have created a new platinum-based, anti-cancer agent able to overcome acquired drug resistance by first modifying the way it is absorbed into cancer cells and then attacking the DNA of those cancer cells. The findings may help researchers design a new generation of anti-cancer drugs that selectively target cancer cells...Massey researchers induce cell death in leukemia
Researchers from the Virginia Commonwealth University Massey Cancer Center today presented preclinical research at the American Association of Cancer Research's annual meeting suggesting the potential of a new combination treatment for chronic lymphocytic leukemia (CLL). In this study, led by Steven Grant, M.D., Massey's associate director of translational research, interactions between...