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Manic in Medical News

Chemical signature of manic depression discovered by scientists

People with manic depression have a distinct chemical signature in their brains, according to a new study. The research, published today in the journal Molecular Psychiatry, may also indicate how the mood stabilisers used to treat the disorder counteract the changes in the brain that it appears to...

Favorable Vote From FDA Advisory Committee on SEROQUEL Pediatric Supplemental New Drug Applications

...r adults in the treatment of depressive episodes in bipolar disorder; acute manic episodes in bipolar I disorder, as either monotherapy or adjunct therapy to...dicated for the treatment of depressive episodes in bipolar disorder; acute manic episodes in bipolar I disorder, as either monotherapy or adjunct therapy to...

FDA Panel Mulls Newer Antipsychotics for Kids

...Fassler added. Drug maker AstraZeneca is asking the FDA to let it market Seroquel to adolescents with schizophrenia and bipolar mania, also called manic depressive disorder. Pharmaceutical giant Lilly is asking for the same permission for its drug, Zyprexa. In addition, drug maker Pfizer wants approval...

Schering-Plough Announces European Filing of SYCREST(R) (asenapine) for the Treatment of Schizophrenia and Bipolar I Disorder

...ST(R) (asenapine) sublingual tablets for the treatment of schizophrenia and manic episodes associated with bipolar I disorder. The application will follow t...e acute treatment of schizophrenia in adults and for the acute treatment of manic or mixed episodes associated with bipolar I disorder in adults as monothera...

Olanzapine Long-Acting Injection (LAI) Efficacy and Safety Data Presented at American Psychiatric Association Annual Meeting

...yprexa (olanzapine) Zyprexa is indicated in adults in the United States for the acute- and maintenance treatment of schizophrenia, acute mixed and manic episodes of bipolar I disorder, and maintenance treatment of bipolar disorder. Zyprexa is not approved for the treatment of patients with deme...

FDA Grants Approval for Use of RISPERDAL(R) CONSTA(R) as Both a Monotherapy and Adjunctive Therapy in the Maintenance Treatment of Bipolar I Disorder

... mood swings from extreme highs (mania) to extreme lows (depression). Type I Bipolar Disorder is characterized based on the occurrence of at least one manic episode, with or without the occurrence of a major depressive episode, and affects approximately 1 percent of the American adult population in any giv...

Schering-Plough Reports Financial Results for 2009 First Quarter

...ablets, which was received in January 2009. SAPHRIS is under review for the acute treatment of schizophrenia in adults and for the acute treatment of manic or mixed episodes associated with bipolar I disorder in adults as monotherapy. (Announced Feb. 20, 2009) Announced a license agreement betwee...

FDA Advisory Committee Recommendation on SEROQUEL XR Supplemental New Drug Applications

...ive episodes associated with bipolar disorder, the manic and mixed episodes associated with bipolar I disor...e episodes associated with bipolar disorder, acute manic or mixed episodes associated with bipolar I disord... of depressive episodes in bipolar disorder; acute manic episodes in bipolar I disorder, as either monother...

New National Online Survey Says Bipolar Depressive Symptoms Have Impact on Day-To-Day Tasks as Well as Social Activities(1)

... moods and inability to concentrate -- than in the manic phase.(4) This fact was confirmed in the online s...g their depressive episodes last longer than their manic episodes.(1) "This survey clearly demonstrat...et al. Impact of Depressive Symptoms Compared with manic Symptoms in Bipolar Disorder: Results of a U.S. Co...

FDA Advisory Committee Recommendation on SEROQUEL XR Supplemental New Drug Applications

...ive episodes associated with bipolar disorder, the manic and mixed episodes associated with bipolar I disor...e episodes associated with bipolar disorder, acute manic or mixed episodes associated with bipolar I disord... of depressive episodes in bipolar disorder; acute manic episodes in bipolar I disorder, as either monother...
Manic in Medical Technology

U.S. Food and Drug Administration Approves ABILIFY(R) (aripiprazole) for the Acute Treatment of Manic and Mixed Episodes Associated With Bipolar I Disorder in Pediatric Patients (10 to 17 Years of Age)

- Otsuka-sponsored Study Evaluated Use of ABILIFY In This Patient Population - TOKYO and PRINCETON, N.J., Feb. 29 /PRNewswire/ -- Otsuka Pharmaceutical Co., Ltd. and Bristol-Myers Squibb Company (NYSE: BMY ) announced today that the U.S. Food and Drug Administr...

FDA Advisory Committee Votes in Favor of SAPHRIS(R) (asenapine) for Acute Bipolar I Disorder and Acute Schizophrenia

...s as effective and safe for the acute treatment of manic or mixed episodes associated with bipolar I disord...ency (EMEA) for the treatment of schizophrenia and manic episodes associated with bipolar I disorder. The ... Disorder Bipolar I disorder (also known as manic depression) is a chronic, episodic illness charact...

FDA Advisory Committee Votes in Favor of Zyprexa for Two Adolescent Indications

...y safe for the acute treatment of schizophrenia or manic or mixed episodes associated with bipolar I disord...cceptable safety. For the proposed indication for manic or mixed episodes associated with bipolar I disord...a in 107 adolescents (aged 13-17 years) with acute manic or mixed episodes associated with bipolar I disord...

RISPERDAL(R) CONSTA(R) (Risperidone) Long-Acting Treatment Delayed the Time to Relapse in Patients with Bipolar I Disorder

...I Bipolar Disorder is characterized based on the occurrence of at least one manic episode, with or without the occurrence of a major depressive episode, and ... Bipolar I Disorder who were stable on medications or experiencing an acute manic or mixed episode. In the first phase of the study, 303 patients were stabil...

Cephalon Announces Positive Results From a Phase Two Study of NUVIGIL in Bipolar Depression

...h is characterized by fluctuations between extreme highs (manic) and lows (depressed) in mood. People with bipolar disorders cycle between periods of manic or depressive mood and typically spend more time in the depressed phase of the illness. The eight-week, double-blind, placebo-controlled study ...

Study Suggests New Treatment Approach May be Needed for Management of Depression in Some People With Bipolar Disorder

...abilizers have proven effective at controlling the manic phase of the illness, but treating the depressive ...mptoms. "We found that people who had minimal manic symptoms or a "mixed depression" presentation were...ought to be a disorder with two distinct phases (a manic upswing and a depressive downswing), may be incomp...

U.S. FDA Issues Complete Response Letter for SAPHRIS(TM) (ASENAPINE) in the Acute Treatment of Both Schizophrenia and Bipolar I Disorder

...omplete response letter for SAPHRIS(TM) (asenapine) sublingual tablets in the acute treatment of schizophrenia in adults and in the acute treatment of manic or mixed episodes associated with bipolar I disorder in adults as monotherapy. The action letter includes proposed labeling for both indications and ...

FDA Issues a Complete Response Letter for Lilly's Olanzapine LAI for Treatment of Schizophrenia in Adults

...nformation for Zyprexa Zyprexa oral is indicated in the United States for the short- and long- term treatment of schizophrenia, acute mixed and manic episodes of bipolar I disorder, and maintenance treatment of bipolar disorder. Olanzapine is not approved for the treatment of patients with d...

Schering-Plough Highlights R&D Pipeline Progress, Innovation and Breadth of Research Projects

...n and certain other Asian markets; SAPHRIS(TM)** (asenapine), a novel psychopharmacologic agent (under U.S. review for schizophrenia and acute manic or mixed episodes associated with bipolar I disorder); pivotal relapse-prevention data were presented showing that only 12 percent of patients receivi...

Schering-Plough Unveils Top-Line Study Results for SAPHRIS(TM) (asenapine) Demonstrating Efficacy in Long-Term Schizophrenia Relapse Prevention

...senapine in Europe in 2009 for treatment of schizophrenia, and treatment of manic episodes associated with bipolar 1 disorder. Asenapine is currently under ... and Drug Administration (FDA) for the treatment of schizophrenia and acute manic or mixed episodes associated with bipolar I disorder. The company acquired...
Manic in Medical Dictionary

Mood disorder

...orders ) is caused by a chemical ... ... II disorder often enjoy being hypomanic (due to elevated mood and inflated ... Bipolar disorder , or manic depression, is characterized by extreme mood swings. ... All about Mood disorders . ... Mood disorders are among the most common diagnose...

Manic Depression

... Bipolar disorder, also known as manic depression , manic depressive disorder or bipolar affective disorder...pression and ... disorder (also sometimes called manic depressive illness) is another depressive ... ...

Manic-depressive

... Bipolar disorder, also known as manic depression, manic depressive disorder or bipolar affective disorder...ipolar. Suggestions for family and friends of manic depressive ... In addition, getting enough slee...

Mania

...tail behemoth "Mega-Mart" moves in, Jill's beloved family... Mania is characterized by excessive physical activity and feelings of elation ... manic psychosis is an extreme form of mania . ... Arsenal Mania - The Arsenal Website For Arsenal Fans - News - Daily Round-Up for 30 December, 200...

Depression

...ymptoms and treatment of depression . Clearinghouse for information on all types of depressive disorders and treatments for major depression , manic depression , cyclothymia, and dysthymia. Wikipedia entry includes van Gogh painting, descriptions of treatments, signs and ... For other depressi...

Bipolar disorder

... Bipolar disorder , also known as manic depression, manic depressive disorder or bipolar affective diso...ted by bipolar I disorder has had at least one manic episode in his or her life. ... Includes comme...
Manic in Biological News

Bipolar disorder genes, pathways identified by Indiana University neuroscientists

...bipolar disorder, and achieve this major breakthrough in our understanding of the illness," Dr. Niculescu said. Bipolar disorder, sometimes called manic depression, affects nearly 2.3 million Americans. A serious illness, people who suffer from it can experience mild or dramatic mood swings, shifts in ...

Adults who eat eggs for breakfast lose 65 percent more weight

...n the yolk, so make sure to eat the whole egg for maximum benefits." Newgent suggests these nutrition tips for a successful weight loss plan: manic Monday: Make a batch of hard-cooked eggs on Sunday, so you'll have all-natural, high-quality protein meals for your on-the-go schedule during the week...

Brain's 'gambling circuitry' identified

...e to misperception of risk or disruptions in cognitive processes, such as learning, planning, and choice. "For example, a bipolar subject during a manic episode may invest in a risky business proposition either because they misperceive the risk to be lower than it actually is, or because they accuratel...
Manic in Biological Technology

Schering-Plough Reports Financial Results for 2009 Second Quarter

...EMEA had accepted for review the Marketing Authorization Application for SYCREST (asenapine) sublingual tablets for the treatment of schizophrenia and manic episodes associated with bipolar I disorder. (Announced June 2) Reported findings from extensions of two Phase III studies showing that subcuta...

Schering-Plough Submits Response to FDA for SAPHRIS(TM) (asenapine) in the Acute Treatment of Both Schizophrenia and Bipolar I Disorder

...ablets, which was received in January 2009. SAPHRIS is under review for the acute treatment of schizophrenia in adults and for the acute treatment of manic or mixed episodes associated with bipolar I disorder in adults as monotherapy. The action letter included proposed labeling for both indication...

Asenapine Meets Primary Endpoint in Long-Term Schizophrenia Relapse Prevention Trial

...which developed the product. Asenapine is currently under review by the U.S. Food and Drug Administration for the treatment of schizophrenia and acute manic or mixed episodes associated with bipolar I disorder. Schering-Plough is an innovation-driven, science-centered global health care company. Through ...

Lilly to Take Charge to Earnings Related to Pending Federal and State Investigations of Past Practices

...ding Zyprexa. Zyprexa Background Zyprexa is indicated in the United States for the short- and long-term treatment of schizophrenia, acute mixed or manic episodes of bipolar I disorder, and maintenance treatment of bipolar disorder. Since Zyprexa was introduced in 1996, it has been prescribed for an est...

FDA Approves AstraZeneca's SEROQUEL XR(R) for the Treatment of Bipolar Depression and Bipolar Mania

...ive episodes associated with bipolar disorder, the manic and mixed episodes associated with bipolar I disor... once-daily acute treatment of both depressive and manic episodes associated with bipolar disorder.(1) "W...rience depressive symptoms three times longer than manic symptoms," said Dr. Trisha Suppes, Professor of Ps...

Strong Double-Digit Net Sales Growth and Solid Earnings Growth Highlight First Quarter for Bristol-Myers Squibb Company

...ug Administration (FDA) for the acute treatment of manic and mixed episodes associated with Bipolar I Disor... ABILIFY(R) in the treatment of moderate to severe manic episodes in Bipolar I Disorder and for the prevention of a new manic episode in patients who experienced predominantly...

AstraZeneca Submits sNDA for SEROQUEL XR(TM) for the Treatment of Major Depressive Disorder

... SEROQUEL XR to seek approval for the treatment of manic episodes associated with bipolar disorder and the ... of depressive episodes in bipolar disorder; acute manic episodes in bipolar I disorder, as either monother...feature between the disorders being the absence of manic or hypomanic symptoms in MDD.(6) It has been repor...

Study Suggests Risperidone Long-Acting Injection Combined with Standard Treatment Helped Delay Time to Relapse in Patients with Bipolar Disorder

... use of a long-acting injection medication in the maintenance treatment of frequently relapsing bipolar disorder (FRBD). FRBD, defined as four or more manic or depressive episodes in the previous year that require a doctor's care, may affect 20% of the 27 million people with bipolar disorder worldwide(2,3)...

Organon's Asenapine Further Demonstrates Efficacy in Reducing Mania Symptoms for the Treatment of Bipolar I Disorder

...acologic agent being developed by Organon -- is effective in treating acute manic episodes associated with bipolar I disorder. These results, from two Phase ...ng Mania Rating Scale) score. The YMRS is an 11-item scale used to evaluate manic symptoms. A difference in YMRS score reduction between the active treatment...

Validus Pharmaceuticals Expands Product Portfolio with Acquisition of Bipolar Drug: Equetro(R)

... the unique Bipolar Disorder treatment, Equetro(R) (carbamazepine) extended release capsules, from Shire plc. EQUETRO(R) is a treatment for the acute manic and mixed episodes associated with Bipolar-1 Disorder -- a condition where patients experience extended periods of exaggerated highs in addition to th...
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