International team cracks mammalian gene control code
An international consortium of scientists, including researchers from The University of Queensland (UQ), have probed further into the human genome than ever before. They have discovered how genes are controlled in mammals, as well as the tiniest genetic element ever found. Their discoverie...CSHL neuroscientists propose project to comprehensively map mammalian brain circuits
Cold Spring Harbor, NY -- Thirty-seven scientists from Cold Spring Harbor Laboratory (CSHL) and 20 other major research institutions in the U.S. and Europe have issued a major challenge to the neuroscience community. At long last, the time has come, they argue in a just-published paper, to assemb...Crystallography reveals the 3-D structure of mammalian sperm receptor
Scientists at the Swedish medical university Karolinska Institutet have determined the first 3D structure of ZP3, a protein essential for the interaction between the mammalian egg coat and sperm. The findings, presented in Nature , gives a first glimpse into the molecular architecture of animal e...Medical College of Wisconsin researchers identify proteins that help develop mammalian hearts
The absence of two proteins in mammalian embryos prevents the development of a healthy heart, a new study by researchers at the Medical College of Wisconsin, Milwaukee, has found. The study, which appears in the May 15 issue of Developmental Biology, was led by Stephen Duncan, Ph.D., professor ...Cannibalistic Signals Help Mammalian Embryos Develop Normally
A process called autophagy spurs dying embryonic stem cells to send cannibalistic signals to have their corpses purged, a last gasp that paves the way for normal mammalian// development. Autophagy is the way cells devour their own unwanted or damaged parts. It was known to be active in cell d...Filling a Niche -- Role of Rb in Mammalian Stem Cells
Drs. Gustavo Leone and Michael Robinson (Ohio State University) and colleagues uncover a stem-cell specific role for the well-known tumor suppressor gene// , Rb, in the developing mammalian embryo. Researchers had previously shown that mice deficient in Rb die as embryos. Using a combination...DSM Announces Yield Boosts of 5-10 Fold With XD(R) Technology for Mammalian Manufacturing Platforms
PARSIPPANY, N.J., May 18 /PRNewswire/ -- DSM announced today that its proprietary XD(R) Technology boosts bioreactor productivity and titers of mammalian cell culture processes by 5-10 fold for the production of proteins and antibodies. Recent studies completed at the R&D labs of DSM Biol...St. Jude Settles Century-Old Debate on Origin of Mammalian Network of Lymphatic Vessels
Embryonic veins are the source of cells that multiply and migrate in the embryo to give rise to the entire network of lymphatic vessels, a finding that suggests that these cells might one day be used to grow new vessels MEMPHIS, Tenn., Oct. 3 /PRNewswire-USNewswire/ -- Investigators at St. ...Researchers Create First Targeted Knockout Rats Using Zinc Finger Nuclease Technology
...lls and zebrafish embryos and are now in human clinical trials for the treatment of HIV/AIDS. This is the first example of successful gene editing in mammalian embryos using this technology. "Our ZFN technology is widely applicable across species," stated Philip Gregory, D.Phil., Sangamo's vice presi...Atomic structure of the mammalian 'fatty acid factory' determined
Mammalian fatty acid synthase is one of the most complex molecular synthetic machines in human cells. It is also a promising target for the development of anti-cancer and anti-obesity drugs and the treatment of metabolic disorders. Now researchers at ETH Zurich have determined the atomic structure...Adult stem cells activated in mammalian brain
Irvine, Calif., July 24, 2008 Adult stem cells originate in a different part of the brain than is commonly believed, and with proper stimulation they can produce new brain cells to replace those lost to disease or injury, a study by UC Irvine scientists has shown. Evidence strongly shows that ...A mammalian clock protein responds directly to light
We all know that light effects the growth and development of plants, but what effect does light have on humans and animals? A new paper by Nathalie Hoang et al., published in PLoS Biology this week, explores this question by examining cryptochromes in flies, mice, and humans. In plants, cryptoch...First high-res 3D structures of mammalian HSP90 protein solved
Dr. Dan Gewirth, Hauptman-Woodward senior research scientist, has just solved the structure of the first mammalian GRP94 protein implicated in immune diseases such as sepsis, AIDS and certain cancers. His work is being published today in a cover article in a top scientific journal - Molecular Cel...St. Jude settles century-old debate on origin of mammalian network of lymphatic vessels
Investigators at St. Jude Children's Research Hospital settled a century-old debate on the origin of the mammalian lymphatic vasculaturethe network of vessels and capillaries critical to various essential housekeeping functions in the body. The finding holds the promise for the development of new ...New Study Finds Growth Factor Boosts Productivity in Mammalian Cell Culture
Leading researchers in academia and industry reveal powerful effects of recombinant lactoferrin (tradename: Lacromin) in mammalian cell culture leading to a significant boost in productivity. FORT COLLINS, Colo., Oct. 10 /PRNewswire/ -- A recently published study in the scientific...InVitria's Cellastim Delivers Superior Results in Mammalian Cell Culture
FORT COLLINS, Colo., Sept. 25 /PRNewswire/ -- Steve Pettit, Director of the company's Cell Culture Group, presented results of InVitria's ( http://www.InVitria.com ) Cellastim in mammalian cell culture at the 2008 BioProcess International Conference in Anaheim, California this week. "Cellast...KGI Offers Mammalian Cell Culture Program for Biotech Industry Professionals
CLAREMONT, Calif., Sept. 18 /PRNewswire/ -- Keck Graduate Institute (KGI) today announced that it will conduct a five-day program for industry professionals to learn the latest developments in mammalian cell culture, from November 2-7, 2008. "Mammalian cell biotechnology has undergone explos...Rentschler Biotechnologie Extends Capacities for Mammalian Cell Culture Manufacturing
Laupheim, Germany – June 20, 2008 / b3c newswire / - Rentschler Biotechnologie, a leading full-service contract manufacturing organization (CMO) for the development and production of biopharmaceuticals in mammalian cells, started operation of a 2,500 L multi-process production suite....Seth Dobin heading up Marshfield's Mammalian Genotyping Service
Marshfield, Wis. -- Research scientist Seth Dobrin, Ph.D., has been named the new head of the Center for Human Genetics' Mammalian Genotyping Service of the Marshfield Clinic Research Foundation. He plans to apply his experience in genetics and genomics research to problems of mental health an...CheckMate Mammalian Two-Hybrid System from Promega
Description: ...PhosphoSafe Extraction Buffer from Novagen
Description:... PhosphoSafe Extraction Reagent extracts cytosolic proteins from mammalian and insect cells while preserving their phosphorylation state. The reagent, an enhancement of the CytoBuster Protein Extraction reagent, includes four...GenoStat Inducible Expression System from Upstate
Description:...n System provides tightly regulated control of exogenous gene expression in mammalian cells and is capable of repeated on/off expression kinetics. This degree of...tilizing the GenoStat Inducible Expression System is unmatched by any other mammalian expression system on the market. Applications: RNAi/siRNA/Gene Kno...mirVana™ qRT-PCR Primer Set for Normalization (5S) from Ambion
Description:...c 2005 Quantitative results in less than 3 hours Detection from as little as 25 pg of total RNA Specific primers available for hundreds of mammalian miRNAs Suitable for either real-time or end-point RT-PCR Ideal for validating expression profiling data and high-throughput applications ...