Malignant

Can EUS elastography help distinguish benign from malignant tissue?

A major limitation of endoscopic ultrasound (EUS) examination is its limited capacity to determine the exact nature of a lesion. The differential diagnosis between benign and malignant lymph nodes and focal pancreatic masses based on the EUS appearance is difficult and frequently requires EUS-guid...

Video: The MDS Foundation Says Published Data Confirms VIDAZA(R) Significantly Extends Survival in Patients with the Malignant Condition MDS

VIDAZA Restores Gene Function to Double Survival and Increase Transfusion Independence CROSSWICKS, N.J., Feb. 18 /PRNewswire/ -- The Myelodysplastic Syndromes (MDS) Foundation says data published in the peer reviewed medical journal The Lancet Oncology confirms VIDAZA extends survival f...

MedPredict Publishes Two New Reports Providing Expert Analysis of Malignant Hematology Drug Development

SCOTTSDALE, Ariz., Jan. 23 /PRNewswire/ -- MedPredict Market Research, a global provider of pharmaceutical competitive intelligence and market research, has published two new reports providing critical strategic insight for companies developing therapies to treat hematologic malignancies. These r...

A Stage IV Malignant Melanoma Drug That Increases Overall Survival Would Earn a Higher Patient Share in the U.S. Than in Europe

Ipilimumab Will Earn Decision Resources' Clinical Gold Standard for Stage IV Malignant Melanoma in 2012, According to a New Report from Decision Resources WALTHAM, Mass., Jan. 19 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms for pharmaceutical an...

MDCT, virtual gastroscopy and MPR images differentiate malignant and benign gastric ulcers

Multidetector CT using virtual gastroscopy and post contrast enhanced multiplanar reformation images can be useful in differentiating between malignant and benign gastric ulcers, according to a recent study conducted by researchers from Kaohsiung Medical University Hospital in Kaohsiung, Taiwan. ...

New regulatory circuit identified for aggressive, malignant brain tumor

Research using a newly developed algorithm has significantly advanced understanding of the molecular events associated with the most common primary brain tumor in adults, human glioblastoma (GBM). The research, published by Cell Press in the April issue of the journal Cancer Cell, validates known ...

More>>

Malignant in Medical Technology

Medarex Announces Enhanced Activity Data with Second Generation Anti-CD30 Antibody for Malignant Lymphoma

PRINCETON, N.J., Dec. 8 /PRNewswire-FirstCall/ -- Medarex, Inc. (Nasdaq: MEDX ) announced today results from a preclinical study for MDX-1401, a second-generation non-fucosylated version of MDX-060 that targets CD30, a marker for activated lymphocytes that is present on the malignant cells of Ho...

Anti-TGF-Beta Antisense AP 12009 Shows Very Good Safety and Tolerability in Systemic Treatment of Pancreatic Carcinoma, Malignant Melanoma and Colorectal Carcinoma

CHICAGO and REGENSBURG, Germany, June 2 /PRNewswire/ -- The TGF-beta 2 inhibitor AP 12009, developed by Antisense Pharma, reveals very good safety and tolerability in the systemic treatment of pancreatic carcinoma, malignant melanoma and colorectal carcinoma. AP 12009, administered intravenous...

International Symposium on Malignant Mesothelioma 2008

Targeting a Cure WASHINGTON, May 28 /PRNewswire/ -- Leading international experts on the asbestos-related cancer, mesothelioma, will join meso patients, caregivers, loved ones and advocates to share the latest in treatment, research and clinical trials at the Mesoth...

Micromet to Present Clinical Update for BiTE Antibody MT103/MEDI-538 at the International Conference on Malignant Lymphomas

BETHESDA, Md., May 22 /PRNewswire-FirstCall/ -- Micromet, Inc. (Nasdaq: MITI), a biopharmaceutical company developing novel, proprietary antibodies for the treatment of cancer, inflammation and autoimmune diseases, today announced that the company will provide an update on the phase 1 clinical...

New Study Shows Proprietary Canola Extract, Dermytol(TM), Produces Pronounced Decrease in Malignant Melanoma Tumor Volume

KGK Synergize Inc. Presents Findings Today SAN DIEGO, April 7, 2008 /PRNewswire/ -- A new study presented at the Experimental Biology Annual Meeting shows that a proprietary blend extracted from canola, Dermytol(TM), produces a pronounced reduction of malignant melanoma cell gro...

AmpliMed Corporation Announces Promising 1-year Survival Data from Phase I/II Study of Amplimexon(R) in Metastatic Malignant Melanoma

TUCSON, Ariz., Jan. 3 /PRNewswire/ -- AmpliMed today reported one year survival results from a Phase I/II trial of its lead drug candidate, Amplimexon(R) (imexon for injection) in combination with dacarbazine in patients with unresectable stage III or stage IV metastatic malignant melanoma. Re...

Malignant in Medical Products

Zilver 518 Biliary Stent

Description:... The Zilver 518 Biliary Stent, a flexible, self-expanding nitinol design intended to treat patients with malignant neoplasms in the biliary system, is now available from Cook Incorporated following clearance by the U.S. Food and Drug Administration. Incorporating t...
Company:Cook Incorporated

Malignant in Medical Definition

Anterior mediastinal mass

...Anterior mediastinal compartment, also known as anterosuperior compartment, is anterior to the pericardium. Masses in this area is more likely to be malignant than those in other compartments (1) Most common masses found here include thymomas, germ cell tumors, lymphomas, thyroid tissue, and parathyroid lesi...

Clean margin

... A clean margin is a medical term referring to the attempt in surgical oncology to resect a tumor with no portion of the malignant growth on microscopic examination by a pathologist extending past a set delineation known as the 'tumor margin'. [1] This is an important issue...

Hematopathology

...are diseases that are mainly based in lymph nodes . Hematopathologists have named different lymphomas after the type of lymphocyte that has become malignant . Thus there are B cell lymphomas , T cell lymphomas , and NK cell lymphomas . The hematopathologist uses immunohistochemistry and flow cyto...

Pathology

... , neoplasia , and oncology ( C00-D48 ) Benign tumors Hyperplastic tumor - Cyst - Pseudocyst - Hamartoma - Benign neoplasm malignant progression Dysplasia - Carcinoma in situ - Invasive cancer - Metastasis Topography Anus - Bladder - Bile duct - Bone - Bra...

Ocular oncology

...nd orbit can be benign like dermoid cysts , or malignant like rhabdomyosarcoma and retinoblastoma . The...de squamous carcinoma , sebaceous carcinoma and malignant melanoma . The most common malignant primary intraocular tumor in adults is melan...

Malignant in Medical Dictionary

Yellow Fever

...ications, risks, statistics, long-term outlook ... Most yellow fever infections are mild. ... Yellow Fever . One of the severest forms of malignant fever ; so named from the lemon or orange ... A remittent fever , with yellow skin from disorder of the ... To identify cases of yellow f...

Vulva

...ly - even though ... The clitoris is at the front of the vulva where the labia minora meet. ... Vulvar cancer is a rare disease in which malignant (cancer) cells form in the tissues of the vulva . ... Tests that examine the vulva are used to detect (find) ... Cancer of the vulva involves...

Thyroid cancer

... Thyroid neoplasm or thyroid cancer usually refers to any of four kinds of malignant tumors of the thyroid gland: papillary, follicular, medullary or anaplastic. Most patients are 25 to 65 years of age when first diagnosed;... ...

Thrombocytopenia

...s can cause thrombocytopenia . Thrombocytopenia can occur when the ... Thrombocytopenia has various causes, among which are both benign and malignant conditions. ... This type of Thrombocytopenia is commonly seen in children and ... Thrombocytopenia is a general term for blood disorders th...

Stomach

...online English dictionary and encyclopedia. stomach ... gastrica - one of several veins draining the stomach walls ... Stomach cancer is a malignant cell growth that begins in the cells of the ... About stomach cancer - Types and differences - Risk factors and causes - Signs ... Radiograp...

Soft tissue

...nt of childhood soft tissue sarcomas. ... More About Childhood Soft Tissue Sarcoma. Get More Information ... Soft tissue sarcomas are malignant (cancerous) tumors that can develop from fat, muscle, nerve, ... types of soft tissue tumors is important. ... Soft Tissue Sarcoma Key Ter...

Malignant in Biological News

New study shows Dermytol produces pronounced decrease in malignant melanoma tumor volume

SAN DIEGO, CA., April 7 . . .A new study presented at the Experimental Biology Annual Meeting shows that a proprietary blend extracted from canola, Dermytol, produces a pronounced reduction of malignant melanoma cell growth. Dermytol, a proprietary compound developed by KGK Synergize Inc., a biot...

Tumor-targeting viral therapy slows neuroblastoma, malignant peripheral nerve sheath tumors

CINCINNATI Researchers in a multi-institutional study led by Cincinnati Childrens Hospital Medical Center slowed the growth of two particularly stubborn solid tumor cancers neuroblastoma and peripheral nerve sheath tumors without harming healthy tissues by inserting instructions to inhibit tissue...

Possible birthplace of malignant brain tumors identified

Researchers have found that abnormal stimulation of a cellular trigger that normally regulates replenishment of brain cells in adults causes invasive tumor-like growths in mice. Removing the abnormal stimulation causes the growths to regress--a finding the researchers said suggests a possible treat...

Stem cell microenvironment reverses malignant melanoma

Northwestern University researchers have demonstrated how the microenvironments of two human embryonic stem cell (hESC) lines (federally approved) induced metastatic melanoma cells to revert to a normal, skin cell-like type with the ability to form colonies similar to hESCs. The researchers also sh...

Newfound roadblock to interferon effectiveness against malignant melanoma

Researchers have uncovered a significant contributing factor to interferon resistance of malignant melanoma cells. The finding represents a step forward in understanding the molecular events that govern the growth of this type of cancer and the changes in gene expression and cellular signaling that...

'Normal' cells far from cancer give nanosignals of trouble

...e that can detect features as small as 20 nanometers, validate the "field effect," a biological phenomenon in which cells located some distance from a malignant or premalignant tumor undergo molecular and other kinds of abnormal changes. The most striking findings were that these nanoscale alterations occu...

Malignant in Biological Technology

Sanofi-aventis Announces Second Quarter 2009 Results

...III. A license agreement has been signed with Exelixis, along with an exclusive research collaboration to discover PI3K inhibitors in the treatment of malignant tumors. We have also entered into a collaboration agreement with Kyowa Kirin. Exploring external growth opportunities - In July, our Vaccines ...

NeoGenomics Reports Second Quarter 2009 Results

...tes and Europe have demonstrated that a very specific FISH panel test containing the genes and IP covered by our agreement with Abbott can distinguish malignant melanoma from pre-malignant or dysplastic nevi with a sensitivity of approximately 87-90% and a specificity of approximately 95%. Over the next six m...

Morphotek(R), Inc. and Cancer Innovations, Inc. Announce Evaluation and Option Agreement for Therapeutic Monoclonal Antibodies

...echnology is based on proprietary discoveries concerning the importance of stromal factors uniquely present within the surrounding microenvironment of malignant tumors. About Morphotek Morphotek((R)), Inc., a subsidiary of Eisai Corporation of North America, is a biopharmaceutical company specia...

Oncolytics Biotech(R) Inc. Research Collaborators Present Glioma Reovirus Research at ASV Annual Meeting

... The investigators concluded that the data supports the use of reovirus in combination with standard radiation and chemotherapies for the treatment of malignant glioma in humans. The poster will be available on the Oncolytics website at www.oncolyticsbiotech.com at a later date. About Oncolytics Biote...

EMcision Announces 510(k) Clearance of the Habib EndoHPB, its Novel Bipolar RF Device for the Palliation of Biliary and Pancreatic Tumours

...b™ EndoHPB can be used to ablate the occluding tissue. "The EndoHPB significantly improves on the procedure for patients suffering from malignant biliary obstruction," stated EMcision's CEO, the internationally renowned surgeon, Professor Nagy Habib. "I am particularly excited about th...

First Catalog Cancer Biochip for Sequence Capture Now Available from febit

...rofessor Eckart Meese, director of the Department of Human Molecular Genetics at Saarland University. "It is of utmost importance for our research on malignant brain cancer to obtain deep sequencing results of the 100 most relevant genes with high sequence coverage using the HybSelect technique. It is equally...

Malignant in Biological Products

Mouse Anti-Human SM22 alpha Monoclonal Antibody, Unconjugated Conjugated, Clone 10H12 from Vision BioSystems

Description:...scular and visceral forms. It is also reported to be expressed in some rare malignant tumors such as malignant fibrous histiocytomas....
Company:Vision BioSystems

Cell Transformation Colorimetric Assay Kit from CHEMICON

Description:... Cell Transformation Detection Assay is an anchorage-independent growth assay in soft agar, which is considered the most stringent assay for detecting malignant transformation of cells. For this assay, cells (pre-treated with carcinogens or carcinogen inhibitors) are cultured with appropriate controls in soft...
Company:CHEMICON

Malignant in Biological Definition

Apoptosis

...ith fragments of inappropriately expressed proteins (resulting, say, from a malignant mutation) or with foreign antigen produced as a consequence of a viral infe...ller T cells, which are then primed for the eradication of cells undergoing malignant transformation. This apoptosis-dependent pathway for T cell activation is n...

Cancer

... cells can lead to either a benign tumor or a malignant tumor (cancer). Benign tumors do not spread to ot...her tissues, and they are rarely a threat to life. malignant tumors can invade other organs, spread to distant ...s of the sample are examined closely to see if all malignant tissue has truly been excised. The nature of the...

Diabetes mellitus

...ing pancreatic beta cells, thus producing "artificial" type 1 diabetes. Other pancreatic problems including trauma, pancreatitis or tumors (either malignant or benign) can also lead to loss of insulin production. Currently , type 1 is treated with insulin injections, lifestyle adjustments, and careful ...

Tumor

... article about cancer for the main article about malignant tumors. Tumor ( American English ) or tumour...mal growth of tissue . This growth can be either malignant or benign . malignant tumors are called cancer . Cancer has the potenti...

Malignant in Biological Dictionary

Tumor

... the brain by the blood stream. ... common sites of the primary tumor which can spread to the ... Wilms tumor , also called nephroblastoma, is a malignant (cancerous) tumor originating in the ... The tumor can be very large and it may spread (metastasize) to ... From the American Brain Tumor Ass...

Small intestine

.... The small intestine begins at the end of the stomach and ends where the colon ... Small intestine cancer is a rare disease in which malignant (cancer) cells form ... The small intestine is part of the body's digestive system, which also includes ... Small Intestine . From The WAL...

Skin cell

... layers of cell with melanin in them, and the ... Skin cancer is a malignant growth on the skin which can have many causes. The most common skin can...are compelling but just how do ... Skin cancer is a disease in which malignant (cancer) cells form in the tissues of the skin . ... skin condition th...

Salivary glands

..... Expert-reviewed information summary about the treatment of salivary gland cancer. ... Salivary gland cancer is a rare disease in which malignant (cancer) cells form ... Salivary glands produce the saliva used to moisten your mouth, initiate ... Secondary infection of salivary glands...

Renal

...ell) Cancer ... Expert-reviewed information summary about the treatment of renal cell cancer. ... Renal cell cancer is a disease in which malignant (cancer) cells form in tubules ... o Medulla – broken into 8-18 striated conical segments = renal pyramids ... Renal artery divides into bran...

Plasma cells

...clonal) ... In most cases of multiple myeloma, the malignant plasma cells all make an identical Ig. ... ...ction to a foreign ... Single tumor comprised of malignant plasma cells that occurs in bone or soft tissu...ired the complex skill of ... As the name implies, malignant plasma cells collect in multiple foci in the b...