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Malformed in Medical News

Preeclampsia May Stem From Malformed Proteins

Yale researchers say discovery could lead to earlier diagnosis, treatment FRIDAY, Jan. 30 (HealthDay News) -- Misfolded proteins may be the cause of preeclampsia, say Yale University researchers. And, they say, the proteins are easy to detect in urine, which could offer a new method of...

Epilepsy Drug Valproate and Lamotrigine Linked To Malformed Fetus

In a study in the March issue of Neurology, the epilepsy drug Valproate has been linked to malformation of fetus //when prescribed to pregnant ladies. For pregnant women with epileptic seizures, often the drug Valproate is prescribed. The new study shows that women who took the drug in their ...

CryoLife Announces Release Date and Teleconference Call Details for 2009 Second Quarter Financial Results

...man heart valve, processed using CryoLife's proprietary SynerGraft((R)) technology, has FDA 510(k) clearance for the replacement of diseased, damaged, malformed or malfunctioning native pulmonary valves. The Company's BioGlue((R)) Surgical Adhesive is FDA approved as an adjunct to sutures and staples for use ...

BioGlue(R) Surgical Adhesive Hits 500,000 Procedure Milestone Worldwide, Company Data Indicates

...human heart valve, processed using CryoLife's proprietary SynerGraft(R) technology, has FDA 510(k) clearance for the replacement of diseased, damaged, malformed or malfunctioning native pulmonary valves. The Company's BioGlue(R) Surgical Adhesive is FDA approved as an adjunct to sutures and staples for use in...

Finding Raises Hope for Treating ALS

...les die off. Its cause is unknown, though an inherited defective gene is suspected in up to 20 percent of cases. Scientists thought it originated with malformed -- or "misfolded" -- proteins that malfunction and lead to the protein aggregates in the brain. The ALS Association says that about 30,000 America...

Big-hearted fish reveals genetics of cardiovascular condition

...rtial loss of CCM2 produces a worse cardiovascular defectfailure to even form critical blood vessels. Third, all of these defects are characterized by malformed cell-cell junctions in the endothelial cells that line these organs. And finally, HEG actually physically interacts with CCM proteins. "It looks li...

FDA Clears New Immune Response Claim for the CryoValve(R) SG Pulmonary Human Heart Valve

... CryoValve SG pulmonary human heart valves. The CryoValve SG pulmonary human heart valve is indicated for the replacement of diseased, damaged, malformed or malfunctioning native or prosthetic pulmonary valves. The valve can be used in conjunction with right ventricular outflow tract reconstruction pro...

Give the foie gras a miss

... organs. In laboratory tests amyloidosis is found to be accelerated by injection of tiny quantities of amyloid fibrils, which induce production of the malformed proteins strands. Greger points out that pt de foie gras is the only food stuff currently known to contain high levels of amyloid fibrils and no de...

New findings on emerging contaminants

...PAHs on zebrafish, which medical researchers have determined to have systems comparable to those of humans. The zebrafish embryos hearts were severely malformed after absorbing PAHs through their skin. What isnt good for them, isnt good for us, Incardona says. Given the amount of PAH emissions that come out...

Super-Thin Drug-Free Coating 'Hides' Stent as It Unblocks Heart Arteries

...for several years to coat tiny particles that embolize (block) arteries and treat a number of conditions, including liver cancer, uterine fibroids and malformed arteries. It's also been tested or is in testing on dental implants, orthopedic implants, breast implants and catheters. Because it is a coating, like...
Malformed in Medical Technology

Positive Mid-Term Results on CryoValve(R) SG Pulmonary Human Heart Valve Presented at Western Thoracic Meeting

...the integrity of the underlying collagen matrix. The CryoValve SG pulmonary human heart valve is indicated for the replacement of diseased, damaged, malformed or malfunctioning native pulmonary valves. The valve can be used in conjunction with right ventricular outflow tract reconstruction procedures (RVOT),...

Clinical Data Reported on Vidaza in Hematologic Malignancies and Advanced Solid Tumors

...tic syndromes are a serious and life-threatening group of diseases in which the bone marrow does not function normally, resulting in the production of malformed or immature blood cells. The disease begins when a defect occurs in the genetic material (chromosomes) of one of the stem cells in the bone marrow. Th...
Malformed in Medical Dictionary

Treacher Collins Syndrome

...... Treacher Collins syndrome is a condition that affects the lower eyelids, the ... Children with Treacher Collins syndrome also have malformed or absent ears (see ... Treacher Collins syndrome (TCS) is a genetic disorder involving abnormal facial development. ... Treacher Colli...

Arteriovenous malformation

...ich grow in the brain. ... focused beam radiation to the malformation , and avoid surgery. ... Cerebral arteriovenous malformation (AVM) is a malformed collection of blood ... While an arteriovenous malformation can occur elsewhere in the body, this ... Online Medical Dictionary and glossary...

Airway

...OTRACHEAL INTUBATION/OTHER ADVANCED LIFE SUPPORT AIRWAY ALTERNATIVES ... out-of-hospital advanced airway management in an urban ... Summary: A malformed airway can wreak havoc with muscle tone and head position. ... This essential airway tube is formed in utero and continues to develop from ... ...
Malformed in Biological News

Brain malformations significantly associated with preterm birth, Wake Forest research shows

...ated with preterm birth, there may be blood clots coming from the placenta, causing brain damage and malformations in the brain and then, perhaps, the malformed fetus induces its own preterm birth or perhaps the coagulopathy causes the preterm birth through some other mechanism. The next step is to look at the...

New insights into progressive hearing loss

...tion of the miR-96 gene seemed to disrupt development of intricate sensory hair cells in the mutant mice. Mice with two copies of the mutant gene had malformed hair cells from birth and the cells degenerated from an early age. In mice with one copy of the mutant gene, the effects were less severe, but became ...

Rare disease provides clues about enzyme role in arrhythmias

.... Timothy syndrome has been reported in only about 20 people worldwide. In addition to causing an irregular heartbeat, Timothy syndrome can cause a malformed heart, autism and other nervous system problems. Timothy Syndrome is a type of long QT syndrome, which can cause sudden death in people with normal-ap...

UCR researchers propose minocycline as a promising drug for patients with Fragile X syndrome

...Fragile X through their basic research. By bringing their unique perspective to Fragile X research, they have helped us to understand why neurons are malformed in this disorder, and more importantly, how we can treat it. "We were so impressed with their work that we just awarded Dr. Iryna Ethell the FRAX...

Various species' genes evolve to minimize protein production errors

...efforts to prevent or tolerate errors in protein production. Their study also suggests that the cost of errors in protein production may lie in the malformed proteins themselves, rather than the loss of functional proteins. Misfolded proteins can build up in long-lived cells, like neurons, and cause neurode...

Weill Cornell science briefs June/July 2008

...od-cell count. Common symptoms of the disease include fatigue, shortness of breath and an enlarged spleen, called splenomegaly, caused by a buildup of malformed red blood cells within the body. The spleen works to filter out these unhealthy cells in order to protect the body from harm, such as in a stroke, but...

Genetics of ALS progression

...uron cell death and the progression of ALS. The researchers characterized a molecular pathway by which mutated SOD1 contributes to the accumulation of malformed proteins inside the endoplasmic reticulum (ER) compartment of motor neuron cells. Beyond a certain threshold, this ER stress induces cell death. I...

Fruit fly helps identify protein critical to eggshell formation that may be pesticide target

...ic science point of view, it's a model for matrix assembly," Dr. LeMosy says. In the case of PCDH15 at least, problems with this protein can result in malformed microvilli and deafness in humans. She believes the vitelline membrane also has a role in embryonic patterning, which is essentially how the embryo le...

Avoiding Spleen Removal for Cooley's Anemia SufferersAvoiding spleen removal for Cooley's anemia suf

...od-cell count. Common symptoms of the disease include fatigue, shortness of breath and an enlarged spleen, called splenomegaly, caused by a buildup of malformed red blood cells within the body. The spleen works to filter out these unhealthy cells in order to protect the body from harm, such as in a stroke, but...

Promising new drug targets identified for Huntington's disease

...stigate further which encourage cells to "eat" the malformed proteins that lead to the disease. Huntington's...r of degenerative diseases marked by build up of a malformed proteins in brain cells, mainly in the basal gangl...he cells can be an effective way of preventing the malformed proteins from building up. However, there are curr...
Malformed in Biological Technology

Sangamo BioSciences Initiates Phase 1 Trial of CCR5-ZFP Therapeutic to Treat HIV/AIDS

...ns. A small fraction of the population carries a mutation in their CCR5 gene, called the delta32 mutation. This mutated version of the gene produces malformed CCR5 proteins, which cannot be used by HIV as a co-receptor. Individuals that have two copies of this mutant form of CCR5 (delta32) are resistant to ...

Sangamo BioSciences Presents Data at ICAAC Demonstrating 'In Vivo' Protection Against HIV Infection by CCR5-ZFN Therapeutic

...ains. A small fraction of the population carries a mutation in their CCR5 gene, called the delta32 mutation. This mutated version of the gene produces malformed CCR5 proteins, which cannot be used by HIV as a co-receptor. Individuals that have two copies of this mutant form of CCR5 (delta32) are resistant to i...

CryoLife Receives FDA 510(k) Clearance for SynerGraft(R) Processed Human Pulmonary Heart Valves

...the integrity of the underlying collagen matrix. The CryoValve SG pulmonary human heart valve is indicated for the replacement of diseased, damaged, malformed or malfunctioning native pulmonary valves. The valve can be used in conjunction with right ventricular outflow tract reconstruction procedures (RVOT),...

Sangamo BioSciences Presents Data Demonstrating 'In Vivo' Protection Against HIV Infection by CCR5-ZFN Therapeutic

...ains. A small fraction of the population carries a mutation in their CCR5 gene, called the delta32 mutation. This mutated version of the gene produces malformed CCR5 proteins, which cannot be used by HIV as a co-receptor. Individuals that have mutant delta32 versions of both of their CCR5 genes are resistant t...
Malformed in Biological Dictionary

Fetus

... Leonardo da Vinci. ... Information about fetus in the free online English dictionary and encyclopedia. human fetus , ... (medicine) a grossly malformed and usually nonviable fetus ... fetus - 22 definitions - Main entree in a delicious buffet. ... Fetus Cannon. fetus chucker. Fetus Cleava...
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