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Mad in Medical News

Farmed fish may pose risk for mad cow disease

LOUISVILLE, Ky. University of Louisville neurologist Robert P. Friedland, M.D., questions the safety of eating farmed fish in the June issue of the Journal of Alzheimer's Disease , adding a new worry to concerns about the nation's food supply. Friedland and his co-authors suggest farmed fish...

Protein Branded As Culprit in Mad Cow Disease

Misfolded protein kicks off brain cell damage, lab study finds THURSDAY, June 11 (HealthDay News) -- Mad cow disease and similar conditions may start with one protein that somehow goes astray and deprives the healthy brain cells of another essential protein, researchers say. Mad co...

It's a Mad Dash in the Race Against Heart Disease

Mrs. Dash(R) Kicks off Virtual Women's Heart Health Dash to Benefit WomenHeart: The National Coalition for Women with Heart Disease CHICAGO, Feb. 3 /PRNewswire/ -- Ever imagine strapping on your sneakers and running across the country for a good cause? Well, now you can, virtually, i...

New Test Scans Beef for Mad Cow Disease

Method enables real-time identification of contaminated tissue, study says TUESDAY, Aug. 12 (HealthDay News) -- The first test for instantly detecting beef that's been contaminated with tissue from a cow's brain or spinal cord during slaughter has been developed by U.S. researchers. Th...

New prion protein discovered by Canadian scientists may offer insight into mad cow disease

Scientists have discovered a new protein that may offer fresh insights into brain function in mad cow disease. Our team has defined a second prion protein called Shadoo, that exists in addition to the well-known prion protein called PrP said Professor David Westaway, director of the Centre for P...

New Diagnostic Test for Mad Cow Disease Developed

Scottish scientists have developed a new technique to diagnose mad cow disease in humans. Researchers at Edinburgh University say that the currently available screening process for the brain condition is not completely reliable, and causes specialists to wrongly tell people that they are ...

Proteins Behind Mad Cow Disease may Protect Against Alzheimer's

A study conducted by University of Leeds researchers suggests that proteins that cause mad cow disease may be exploited to protect against Alzheimer's. In laboratory tests, the researchers observed that high levels of the prions in the brain prevented the accumulation of beta amyloid, the ...

Researchers Develop Resin Beads That Capture Mad Cow Disease Agent From Blood

For the first time, experimental results indicate that it is possible to use a resin filter to remove harmful prion proteins from the blood of an infected animal, //a finding that has major implications for the removal of infectious prion proteins – the agents associated with variant Creutzfeldt-Ja...

Early Treatment May Thwart Mad Cow-Type Disease

A number of brain diseases caused by mutant prion proteins, such as mad cow disease or scrapie in sheep, //might be averted if normal prion proteins can be depleted, researchers report. Prion disease, which includes the human form of mad cow disease called variant Creutzfeldt-Jakob disease, i...

Potentially Pathogenic Virus Found in Mad Cow Cells

The alternative view that a virus causes spongiform encephalopathies of the brain, such as 'mad cow' and Creutzfeldt-Jakob (CJD) disease, rather than prion// proteins, which are normally produced throughout life, is bolstered in a new study by Yale School of Medicine researchers. The report p...

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Mad in Medical Technology

Variant of Mad Cow Disease May Be Transmitted by Blood Transfusions, According to Animal Study

WASHINGTON, Aug. 28 /PRNewswire-USNewswire/ -- Blood transfusions are a valuable treatment mechanism in modern medicine, but can come with the risk of donor disease transmission. Researchers are continually studying the biology of blood products to understand how certain diseases are transmitt...

InterMune Provides Additional Information on ITMN-191 (R7227) MAD Study Results

BRISBANE, Calif., April 2, 2008 /PRNewswire-FirstCall/ -- Following its press release and conference call of April 1, 2008, InterMune, Inc. (Nasdaq: ITMN ) today provided additional information on its Phase 1b multiple-ascending-dose (MAD) study of ITMN-191 to facilitate comparison with previ...

InterMune Announces Start of 14-Day Triple Combination Study of ITMN-191 in Patients With Chronic Hepatitis C

... - Fifth cohort of mad study supports continued development in treatment-experi... patients. InterMune expects to submit results from all dose cohorts in the mad study for possible presentation at the Annual Meeting of the American Assoc...

InterMune Announces Top-Line Results of Phase 1b Trial of ITMN-191 (R7227) and Provides Program Update

...ultiple doses of ITMN-191 given as monotherapy on viral kinetics, viral resistance, pharmacokinetics, safety and tolerability. A principal goal of the mad study is to help choose the range of doses of ITMN-191 that when administered in combination with Pegasys(R) (pegylated interferon alfa-2a) and Copegu...

Pharmacopeia Completes Enrollment in Phase 2 Hypertension Study with PS433540 (DARA)

...pport that this result is a strong indication that PS433540 can be expected to lower blood pressure in hypertensive patients. Additional data from the mad study demonstrated that PS433540 produced statistically significant, dose dependent increases versus placebo in plasma-renin activity, as well as redu...

Pharmacopeia Announces Additional Positive Findings from Phase 1 Multiple Ascending Dose Study of PS433540 (DARA)

...on to previously reported initial results from the mad trial that showed all doses of PS433540 to be safe and well-tolerated. This mad study was designed to evaluate the 14-day safety a... to 1,000 mg are the most important results of the mad study, we are especially pleased to see, that even...

Ardea Biosciences, Inc. Announces New Clinical Development Program Directed Toward the Treatment of Gout

...d triglyceride levels was reported. Further analysis of the data from the mad study showed a statistically significant, exposure-dependent reduction in s...se group. Effect of RDEA806 on Serum Uric Acid (SUA) Levels in Phase 1 mad Study Mean SUA Level (mg/dL) ...

R-CALF United Stockgrowers of America: 'Fighting for the U.S. Cattle Producer'

...ver 30 months (OTM) of age, scheduled to begin Nov. 19. The plaintiffs maintain that Canada's problems with bovine spongiform encephalopathy (BSE), or mad cow disease, pose a threat both to the health of the U.S. cattle herd and to U.S. beef consumers. WHEN: 9 a.m. EDT, West Room, National Press Club, ...

K-State Researchers Bringing Expertise to Kansas City Symposium on Disease and National Security

...standing of prion diseases, especially bovine spongiform encephalopathy, or mad cow disease. He'll discuss the molecular features of typical and atypical cases of mad cow disease, the molecular nature of influenza virus evolution and will int...

InterMune Presents Research on ITMN-191 in Hepatitis C at Digestive Disease Week Meeting

...ll tolerated and safe at the doses intended for the Phase 1b multiple-ascending dose (MAD) trial of ITMN-191. InterMune currently anticipates that the mad trial will begin in the third quarter of 2007 and initial top-line viral kinetic data reported in the fourth quarter of 2007. InterMune and Roche have...

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Mad in Biological News

Tracking down the cause of mad cow disease

This release is available in German . The cause of diseases such as BSE in cattle and CreutzfeldJakob disease in humans is a prion protein. This protein attaches to cell membranes by way of an anchor made of sugar and lipid components (a glycosylphosphatidylinositol, GPI) anchor. The ...

K-State professor's USDA research shows mad cow disease also caused by genetic mutation

MANHATTAN, KAN. -- New findings about the causes of mad cow disease show that sometimes it may be genetic. "We now know it's also in the genes of cattle," said Juergen A. Richt, Regents Distinguished Professor of Diagnostic Medicine and Pathobiology at Kansas State University's College of Veter...

Federal testing for mad cow disease a failure, law review editor says

The U.S. Agriculture Department's mad cow disease-testing program is wholly inadequate and the agency's refusal to let processors do their own testing further undercuts the safety of American beef, a University of Illinois scholar writes. Eating meat from cattle infected with bovine spongiform en...

Successful cell engineering may lead to mad cow prevention, say researchers

Researchers at Texas A&M University have successfully "knocked down" the expression of possible disease-causing genes in a cloned goat fetus, perhaps paving the way for breeding disease resistance in other animals, even those genes that might cause bovine spongiform encephalopathy (BSE), common...

Iron is involved in prion disease-associated neuronal demise

...e other neurodegenerative conditions, prion disorders are sporadic, inherited, and infectious, and affect both humans and animals; common examples are mad cow disease in cattle, scrapie in sheep, and Creutzfeldt-Jakob disease in humans. The causative agent is a misfolded protein referred to as PrP-scrapi...

Antibody key to treating variant CJD, scientists find

...ected through the consumption of cattle products contaminated with Bovine Spongiform Encephalopathy (BSE) a brain disorder in cows, commonly known as mad Cow Disease. Prion diseases can develop when a naturally occurring brain prion protein called, PrP, comes into contact with infectious prions. Thi...

Common soil mineral degrades the nearly indestructible prion

...arped pathogens that lack both DNA and RNA, prions are believed to cause such fatal brain ailments as chronic wasting disease (CWD) in deer and moose, mad cow disease in cattle, scrapie in sheep and Creutzfeldt-Jakob disease in humans. In addition to being perhaps the weirdest infectious agent know to sc...

Girls have superior sense of taste to boys

...e declare they are not fussy eaters. Past studies have shown that children who like sour things tend not to be nearly as fussy as children who are not mad about sour foods. Those who prefer sour flavours are also more open to tasting new foods. ...

'Fly guy' makes memory breakthrough

...manipulates their genes and then tests their mental abilities. He's called the "fly guy," and he may sound like a comic book villain, but Bolduc is no mad scientist. A new recruit to the University of Alberta's Faculty of Medicine & Dentistry, Bolduc has shown that genetically disrupting a specific g...

American Chemical Society's Weekly PressPac -- Aug. 6, 2008

... Test to protect food chain from human form of mad Cow Disease Journal of Agricultural and Food Che...cting against possible spread of the human form of mad Cow Disease. The study is scheduled for the August...bovine spongiform encephalopathy," better known as mad Cow Disease. "No currently available method enable...

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Mad in Biological Technology

Lets Use Science to Corral Mad Cow Disease and the Public Stampede

Madison, Wis. During the height of the mad cow scare in Great Britain, the parody newspaper The Onion ran a story headlined English beef approved for Irish consumption. The headline was good for a laugh but it also carried a smidgeon of truth about how choices were made during the 1996 British ou...

Staying sane in a MAD world

The business world is going MAD again. That is MAD as in mergers, acquisitions and divestitures. The value of MAD that took place in the fourth quarter of 2004 outpaced all of 1999 heretofore a record year for corporate buying and selling activity. And 2005 is shaping up to be a blockbuster as w...

InterMune Reports Second Quarter 2009 Financial Results and Business Highlights

... combination with standard of care in August; our plans to start a Phase 1b mad study of ITMN-191 in combination with low dose ritonavir in HCV patients in...--------------------- ----------- Initiate ritonavir boosting mad study in HCV Patients ...

GeneThera Extends its Reach Overseas

...er tests that are presently not available from other technologies. The GES is designed for a host of individual diseases, the current priorities being mad Cow disease, E. coli 0157:H7 and Johne's disease. For more information, contact Dr. Tony Milici at 303-463-6371 or Richard Dopkin at JR Dopkin & A...

International science consortium publishes analysis of domestic cattle genome sequence

...ategies for treating and preventing diseases that affect cattle. Some of those diseases, including bovine spongiform encephalopathy, commonly known as mad cow disease, also can be transmitted although very rarely to humans. Like humans and other mammals, the chromosomes of domestic cattle contai...

Publication of Shire plc's Annual Report 2008

... and ELAPRASE. The discovery of additional cattle in North America or the discovery of cattle in New Zealand with bovine spongiform encephalopathy, or mad cow disease, could cause the regulatory agencies in some countries to impose restrictions on these products, or prohibit the Group from using these pr...

Could Database Software Help Cure Alzheimer's and Save the Earth?

...mensional structures. Experts believe that incorrectly folded proteins may be responsible for some of the most menacing diseases of our era, including mad cow disease, Alzheimer's disease, Parkinson's disease, emphysema and cystic fibrosis. Because experimental approaches provide only limited amounts o...

STC.UNM Signs License Option Agreement With GeneThera for E. coli O157:H7 Vaccine

...er tests that are presently not available from other technologies. The GES is designed for a host of individual diseases, the current priorities being mad Cow disease, Chronic Wasting Disease, E. coli 0157:H7 and Johne's disease, all diseases affecting cattle worldwide. For more information, contact Dr. ...

[video] Dr. Tony Milici, Chairman and CEO of GeneThera, Inc., Discusses Worldwide Rights to E.Coli Vaccine on WallSt.net's 3-Minute Press Show

...ffer tests that are presently not available from other technologies. The GES is designed for a host of individual diseases, the current priority being mad Cow disease, Chronic Wasting Disease, E.Coli 0157:H7 and Johne's disease, all diseases affecting cattle worldwide. About WallStreet Direct, Inc. W...

InterMune to Present Four Abstracts on HCV Protease Inhibitor ITMN-191 at the AASLD Meeting

...e of other direct antiviral compounds studied in similar experiments. The mad study also included one exploratory cohort of ITMN-191 given as mono-therap... -- Pharmacokinetic (pk) and Pharmacodynamic (pd) Results in the Phase 1b mad Study (Poster #1861): ITMN-191 was intentionally designed to achieve a high...

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Mad in Biological Definition

Francis Crick

...gy for his other interest, consciousness . His autobiographical book What mad Pursuit includes a description of why he left molecular biology and switch...(Prometheus Books, 2004; original edition 1967) ISBN 1591021855 What mad Pursuit: A Personal View of Scientific Discovery (Basic Books reprint edit...

Prion

...red between mammalian and yeast prions. The prion variant responsible for mad cow disease has the remarkable ability to bypass the species barrier to t.... Dr. Sean Heaphy, Leicester University. Madcowering A BSE-TSE blog. mad Cow Disease Information from the Center for Global Food Issues. ...
Mad in Biological Dictionary

Xenobiology

...co, 2:07 PM. Tue Jul 28. 34 ... The Lab of Dr. Brainz, a secret research center that covers all manner of theoretical scientific subjects including mad Science, Alternative Energy, Antigravity, ... Observations on Xenobiology . Species: Time Lord. by Dr. Grace Holloway. Cardiovascular system. I .....

Cross breeding

...eding ... Christian Science Monitor, Cross - breeding American chestnut trees is a challenge ... Pacers and Pistons are cross - breeding to create mad Ants. ... with cross breeding . We breed the stockier, calm, healthy Paris. Poodle. ... two different breeds there can be absolutely no guaran...

Cork cambium

...ew years. ... Secondary meristems (vascular cambium and cork cambium ) then add girth to the ... The cork cambium , phellem, and phelloderm mad us the the periderm, or bark. ... 2. Cork cambium - gives rise to the periderm which replaces the epidermis in woody plants ... c. Phellode...

Chaperone Proteins

...h free online dictionary, ... chaperone protein . the drowsy chaper... verizon wireless ... the drowsy chaper... Yeast chaperone protein and mad cow disease. Article highlights or off-site fulltexts 1, 2 ... Chaperone -supervised conversion of prion protein to its protease ... The fir...

Chaperone protein

...More Not Always Better ... Dysregulation of this chaperone protein may underlie the type of wasting seen in ... Yeast chaperone protein and mad cow disease. Article highlights or off-site fulltexts 1, 2 ... Chaperone -supervised conversion of prion protein to its protease ... Chaper...
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Breaking Medicine News(10 mins):Health News:Snoring: Bad for Relationships, Bad for Health 2Health News:Snoring: Bad for Relationships, Bad for Health 3Health News:Leaky Gut Cure Review Reveals Unique Method to Stop Chronic Symptoms 2Health News:LiveStreamingFitness.com is New Trend In Fitness 2Health News:Big Name Bank Hacks Highlight the Importance of Regular Testing and Effective Emergency Response 2Health News:Big Name Bank Hacks Highlight the Importance of Regular Testing and Effective Emergency Response 3Health News:Big Name Bank Hacks Highlight the Importance of Regular Testing and Effective Emergency Response 4Health News:Big Name Bank Hacks Highlight the Importance of Regular Testing and Effective Emergency Response 5
(Date:8/29/2014)... been known about what genetic changes transform wild animals ... of whom is a University of Montana assistant professor, ... the development of the brain and the nervous system ... published Aug. 28 in Science and gives ... http://www.sciencemag.org/ ., The domestication of animals and plants, ...
(Date:8/29/2014)... and number of connections in transcription factor networks (TFNs) ... a study published in PLOS Computational Biology ... signature contributes to a network,s resilience against mutations. ... assortativity of TFN models has a greater effect on ... of assortativity," said Dov A. Pechenick, PhD, lead author ...
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