MacroVascular

Effect of Strict Diabetes Control on Heart Still Unclear

...ergenstahl, executive director of the International Diabetes Center in Minneapolis and ADA's president-elect of medicine and science. "Data related to macrovascular effects on the heart are less well understood or less conclusive." Research presented last year on the ACCORD trial found that intensive lowering o...

Drug May Lessen Amputation Risk for Diabetics

...eight was found to be a major predictor of amputations, with a 1.6-fold increase for every additional 10 centimeters in height. "Classic markers of macrovascular and microvascular risk were associated with lower-extremity amputations in patients with type 2 diabetes," concluded Professor Anthony Keech, of the N...

FDA Approves ACTOplus met(R) XR (pioglitazone HCl and metformin HCl extended-release) Tablets for the Treatment of Type 2 Diabetes

...TO plus met XR must be swallowed whole and not chewed, cut, or crushed. There have been no clinical studies establishing conclusive evidence of macrovascular risk reduction with ACTO plus met, ACTO plus met XR, or any other antidiabetic drug. Please visit the Takeda Pharmaceuticals North America, Inc...

Glitazones have not yet been sufficiently investigated

...late vascular complications IQWiG found no proof in the available study data of an additional benefit of glitazones with regard to late micro- and macrovascular complications of type 2 diabetes (e.g., cardiac disease, stroke, eye or kidney damage) or mortality. However, the findings provide indications of an ...

Experts Say Blood Sugar Guidelines Remain Effective

...ingent AIC goals should be considered for diabetes patients with a "history of severe hypoglycemia, limited life expectancy, advanced microvascular or macrovascular complications, extensive comorbid conditions, and those with longstanding diabetes in whom the general goal is difficult to attain despite diabetes se...

New Criteria Could Expand Number of Liver Transplant Candidates

...ver cancer patients with a single tumor of 5 centimeters or less in diameter, or three or fewer tumors, each no more than 3 cm in diameter and with no macrovascular invasion, can expect an excellent outcome after liver transplantation, with only a 10 percent risk of cancer recurrence. Survival of patients who d...

Hypertension May Hit Black Males Earlier

...d in older people and is associated with atherosclerosis. "Although having a similar cardiovascular risk factor profile as young white men, diffuse macrovascular and microvascular dysfunction is present at a young age in apparently healthy African-American men," the researchers wrote. "Values seen are comparabl...

New Study Data: JANUVIA™ (sitagliptin) Significantly Reduced Blood Sugar Levels and Was Not Associated with Hypoglycemia in Elderly Patients with Type 2 Diabetes

...inical studies establishing conclusive evidence of macrovascular risk reduction with JANUVIA or any other anti-diab...MAJOR CHANGES Warnings and Precautions macrovascular Outcomes (5.4) 07/2008 INDICATIONS AND USAGE...inical studies establishing conclusive evidence of macrovascular risk reduction with JANUVIA or any other anti-diab...

Studies Differ on Benefits of Aggressive Blood Sugar Control

...ivision at the George Institute for International Health in Sydney, Australia, said during a teleconference Friday. "There were no clear effects on macrovascular complications such as heart attack or stroke," Patel said. "Most importantly, using the strategy we employed for intensive glucose control, there was ...

A rare case of ischemic colitis caused by chronic venous insufficiency

...al and clinical findings. A sudden drop in the colonic blood supply is key to its development. However, chronic venous insufficiency by obstruction of macrovascular mesenteric vein rarely causes ischemia of the bowel. This report describes the first case of ischemic colitis caused by obstruction of the mesenteric ...

MacroVascular in Medical Technology

Diabetes Patients with High Triglycerides and Low HDL Cholesterol Get the Most Benefit From Fenofibrate Treatment: New Data From the FIELD Study

...rne , Austin and Northern Clinical Schools, added: These findings on macrovascular disease build on earlier results of the FIELD trial showing clear benefits ...ria and non-traumatic lower-extremity amputation. What were the key macrovascular findings in the FIELD study? After a mean of 5 years treatment, feno...

New Data Showed ACTOS(R) (pioglitazone HCl) Prevented Progression of Atherosclerotic Plaque Volume in Patients With Type 2 Diabetes

...active (PROspective PioglitAzone Clinical Trial In macrovascular Events) trial, which showed that ACTOS was not ass...238 patients with type 2 diabetes and a history of macrovascular disease, who were force-titrated up to 45 mg daily...is study, there was no difference in the number of macrovascular events between standard of care and ACTOS, and sta...

Synvista Announces New Data Showing Haptoglobin Type Predicts Effectiveness of Tight Glycemic Control on Cardiovascular Outcomes in Patients with Diabetes

...pted that tight glycemic control can limit microvascular disease like retinopathy in patients with diabetes, the potential benefits of such control on macrovascular disease have been less clear. This large, prospective evaluation of Hp typing, for which Synvista is developing a clinical diagnostic test, demonstrat...

ACTOS(R) (pioglitazone HCl) Demonstrates Reduced Risk of Ischemic Cardiovascular Disease in Patients with Type 2 Diabetes

..., senior medical director of diabetes and metabolism. "These outcomes - in a real world setting - are consistent with findings of no increase in total macrovascular events or death from PROactive, a prospective, randomized, controlled outcomes study." Case records from January 2003 through June 2006 from a large ...

MacroVascular in Medical Dictionary

Distal

... Types I–III are termed macrovascular disease, whereas type IV disease is termed distal disease. ... Type IV ( distal ) disease in the upper limb. ... Shop for The Distal Limb ...

MacroVascular in Biological News

Hypertension develops early, silently, in African-American men

... as the blood flows through with each beat of the heart. "Although having a similar cardiovascular risk factor profile as young white men, diffuse macrovascular and microvascular dysfunction is present at a young age in apparently healthy African American men," the authors wrote. "Values seen are comparable to...

Backpack straps can decrease blood flow in the shoulder and arm

...eased from 2.66 0.36 to 1.52 0.27 mL/s (p Conclusions The researchers concluded that backpack loads of just 26 pounds decrease upper extremity macrovascular and microvascular blood flows, and may result in a loss of fine motor control and increased fatigue. According to Timothy Neuschwander, MD, the first ...