Molecular machine may lead to new drugs to combat human diseases
The crystallized form of a molecular machine that can cut and paste genetic material is revealing possible new paths for treating diseases such as some forms of cancer and opportunistic infections that plague HIV patients. Purdue University researchers froze one of these molecular machines, which are chemical complexes known as a Group I intron, at mid-point in its work cycle. When frozen...Building a protein name dictionary from full text: a machine learning term extraction approach
The majority of information in the biological literature resides in full text articles, instead of abstracts. Yet, abstracts remain the focus of many publicly available literature data mining tools. Most literature mining tools rely on pre-existing lexicons of biological names, often extracted from curated gene or protein databases. This is a limitation, because such databases have low coverage o...DNA constraints control structure of attached macromolecules
A new method for manipulating macromolecules has been developed by researchers at the University of Illinois at Urbana-Champaign. The technique uses double-stranded DNA to direct the behavior of other molecules. In previous DNA nanotechnology efforts, duplex DNA has been used as a static lattice to construct geometrical objects in three dimensions. Instead of manipulating DNA alone into s...Scientists take aim at virulent bacteria by decoding machinery of key control enzyme
By deciphering the ingenious mechanism used by a particular enzyme to modify bacterial chromosome chemistry, scientists have come a step closer to designing a new kind of drug that could stop virulent bacterial infections in their tracks. Their research will be published in the May 6 issue of the journal Cell. Scientists have known for many years that an enzyme called Dam (DNA adenine meth...Functional Genomics & Pharmacogenomics from Dominion Pharmakine S.L.
Description:Gene expression profiling allows a high-throuput screening of a biological systems phenotype, so that naturally occuring or artifitially induced changes in the expression levels of the genes in that system can be detected, studied, classified and compared to each other, covering a broad range of genes at a glance. Automatized scanning of the hybridized slides in Agilent Technologies G2565 Microar...Functional Proteomics & Pharmacoproteomics from Dominion Pharmakine S.L.
Description:The proteomic service includes protein separation by two-dimensional electrophoresis (2D-PAGE), image analysis using the PDQuest software package from Bio-Rad and protein identification by MALDI-TOF mass spectrometry. In order to meet customers requirements regarding experimental design, sample preparation, data analysis and format of the results permanent contact with our Functional Proteomic Un...MACS Protein A/G Starting Kit from Miltenyi Biotec
Description:Kit containing MACS equipment and reagents for immunopurification of proteins....Pharmaceutical Compounding Chamber from Terra Universal, Inc.
Description:This sealed isolation chamber provides a safe, clean environment for compounding and repackaging sterile pharmaceuticals, in accord with USP-797 requirements. HEPA filtration module creates Class 100 (ISO 5) cleanliness conditions in the work area. Includes an antechamber, IV rod and tilt-up front panel for easy access and cleaning....Purification of the Components of Human Macular Carotenoid-Binding Complex, Rev A
The macular region of the human retina is responsible for almost all color vision and most of the high resolution visual acuity. This part of the retina, known as the macula lutea, or yellow spot, accumulates approximately 200 ng of two closely-related compounds, lutein and zeaxanthin....Third Wave receives FDA clearance of pharmacogenetic test
It is the first pharmacogenetic test to be approved by the FDA for use as a companion diagnostic to a specific drug therapy. The test is c...Rapid PCR* Using Active Tube Temperature Control On Thermo's PCR Machines
Solutions Note The time taken to complete a standard PCRprotocol is becoming increasingly important forresearchers today. Whilst many manufacturers ofthermal cyclers focus on pushing the limits of ramprates, in this article we highlight how Thermo's approach of focussing on ach...South Africa Wins landmark case against pharmaceutical giants
South Africa has scored a landmark legal victory over pharmaceutical giants wanting to stop South Africa from importing cheap AIDS drugs. The country with largest number of AIDS patients in the world now wants to secure affordable drugs from around the world to tackle its AIDS epidemic. The Health Ministry of South Africa, published 70 pages of draft legislation that would allow it to s...Pharmaceutical giant offers AIDS related antifungal drug free to 50 countries
Diflucan Partnership seems to be the latest mantra of Pfizer. The pharmaceutical giant has announced that it will supply free antifungal drug to 50 countries hardest hit by the AIDS virus. The decision by the Pfizer comes close on the heels of the South African Government winning a landmark case against pharmaceutical companies. In an announcement on Wednesday Pfizer said AIDS related a...Pharmaceutical giant offers AIDS related antifungal drug free to 50 countries
Diflucan Partnership seems to be the latest mantra of Pfizer. The pharmaceutical giant has announced that it will supply free antifungal drug to 50 countries hardest hit by the AIDS virus. The decision by the Pfizer comes close on the heels of the South African Government winning a landmark case against pharmaceutical companies. In an announcement on Wednesday Pfizer said AIDS related a...Lose stomach for Life....Preventive removal of stomach saves the risk of cancer
This is a story about five gentlemen with a rare genetic mutation that confers a very high risk of stomach cancer. Yes! Dr. David G. Huntsman of the British Columbia Cancer Agency in Vancouver, Canada and colleagues report on five members of two families with a rare form of hereditary gastric cancer caused by a mutation of the E-cadherin gene. These people had a very bad family histo...Setting up a new pharmaceutical industry in India
Erweka Germany is setting up a new pharmaceutical company in India in the name of Erweka India Pvt Ltd to be based at Ahmedabad. Erweka has started manufacturing 50 years ago in Germany and today is world leader in testing equipment. Erweka, Germany, one of the biggest manufacturer - Supplier of testing and R&D equipment to phamaceutical industries worldwide has a strong brand name in the...Mackool-Bechert Nucleus Rotator
Description:The popular Bechert nucleus rotator has been modified to have the shaft angled 10 mm from tip to bend for ease of manipulation of the lens nucleus in the anterior chamber. Round knurled handle....BioSante Pharmaceuticals Announces New Findings for Potential Bird Flu Vaccine
LINCOLNSHIRE, Ill.--(BUSINESS WIRE)--Jul 11, 2007 - BioSantePharmaceuticals, Inc. (Amex: BPA) today announced new positiveresults demonstrating that its calcium phosphate (CaP)nanoparticle-based vaccine adjuvant, BioVant(TM), may serve as aneffective vaccine adjuvant for the development of a dose sparingvaccine against H5N1 avian flu, widely known as bird flu. The new results are based on...Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone
- Results Fail to Demonstrate Meaningful Placebo Adjusted WeightLoss; Obesity Program to be Discontinued NEW YORK, July 09, 2007 /PRNewswire-FirstCall/ -- ManhattanPharmaceuticals, Inc. today announced results of the company's twoPhase 2a clinical trials of oral Oleoyl-estrone (OE). The resultsof both randomized, double-blind, placebo-controlled studies, onein common obesity and the other...Auxilium Pharmaceuticals to Present at the 2007 CEUT Emerging Growth Opportunities Conference
MALVERN, Pa., June 28, 2007 /PRNewswire-FirstCall/ -- AuxiliumPharmaceuticals, Inc. today announced that Mr. Armando Anido, ChiefExecutive Officer and President, and Mr. Jim Fickenscher, ChiefFinancial Officer, will participate in the 2007 CEUT EmergingGrowth Opportunities Conference to be held July 10 through July 12,2007 at the Mandarin Oriental Hotel in New York City. Mr. Anido issche...