MDR1 Shift Assay from CHEMICON
Description:The CHEMICON MDR1 Shift Assay provides a convenient method to probe conformational changes in MDR1 that occur upon transport of MDR1 substrates. Thus, the kit may be used to determine the extent to which small molecules act as transport substrates for MDR1. Because UIC2 binding is drastically increased in the presence of MDR1 substrates, the MDR1 Shift Assay can be utilized for improved, highly s...