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Luminal in Medical News

Prescient Medical Receives Frost & Sullivan Product Innovation of the Year Award

...hs related to heart attacks using the vProtect(TM) luminal Shield. Heart attacks are now widely belie...disrupts blood flow to the heart. The vProtect(TM) luminal Shield is a self-expanding nitinol device designed...t, Frost & Sullivan. The vProtect(TM) luminal Shield recently completed phase 1 first-in-human t...

Breast cancer etiology may vary by subtype

...cs of women with different breast cancer subtypes: luminal A, luminal B, triple negative and Her2-overexpressing. She sa...oses". The researchers found that patients with luminal B tumors were generally younger at diagnosis than ...

OrbusNeich Files Patent Infringement Lawsuit Against Boston Scientific

...ing Helical Elements." In its complaint Orbus alleges, among other things, that BSC has infringed these two Orbus patents relating to its proprietary luminal stent technology. Specifically the complaint alleges: In July of 2000, the Company entered into a Confidential Disclosure Agreement (...

Bioabsorbable stents show promise

...ears, and images showing the stents had disappeared to a great extent, which was a very promising finding. The study showed an overall 19 % loss in luminal diameter at 18 months and an angiographic in- stent late loss of 0.48mm at two years. These results fall intermediate between those commonly seen for ...

New Test May Mean Faster Breast Cancer Treatment

...dentify each of the four types of breast tumors -- luminal A, luminal B, HER2-enriched and basal-like. A genetic test ca...ast cancer patients would respond to chemotherapy. luminal A was not sensitive to chemotherapy, which suggest...

Cell microenvironments hold key to future stem cell therapies

...e in Denmark. Human breast tissue harbors two types of epithelial cells: luminal - the cells that are able to produce milk and generally the ones that become cancerous; and myoepithelial the cells that surround the luminal cells and push milk down the ducts to the nipples, but which rarely become ...

New genomic test can personalize breast cancer treatment

...ypes have been previously defined and are known as luminal A, luminal B, HER2-enriched and basal-like. The latter three ...s or HER2 gene expression status. They found that luminal A was not sensitive to the chemotherapy, suggestin...

GEN Reports on Strategies to Overcome Blood-Brain Barrier

...factor (IGF), leptin, transferrin, and low-density lipoprotein (LDL). In RMT, molecules in the circulation may bind to specific receptors on the luminal surface of brain capillaries (i.e., the surface that interfaces with the bloodstream). Upon binding, the receptor-ligand complex is internalized into ...

Also in the Dec. 30 JNCI

...of breast cancer. Researchers have identified five subtypes of breast cancer by their gene expression patterns. The subtypes basal, HER2-positive, luminal A and B, and normal-like vary in their natural history and response to therapy. CellSearch is an antibody-based test, approved by the U.S. Food and D...

A new screening test for chronic abdominal pain

... Evaluation of chronic abdominal pain of luminal etiology is a challenging problem for the primary ...g tool for subjects with chronic abdominal pain of luminal origin where site of involvement (small or large b... screening subjects with chronic abdominal pain of luminal origin. Following this approach, one would be able...
Luminal in Medical Technology

vProtect(TM) Luminal Shield Stabilizes Vulnerable Plaque

Six-Month Follow-Up Shows Reduced Stenosis, Healthy Endothelial Regrowth in Vessel Treated Proactively for Vulnerable Plaque DOYLESTOWN, Pa., June 1 /PRNewswire/ -- Six months after placement of a vProtect(TM) Luminal Shield to treat a "vulnerable" plaque, a follow-up exam revealed reduced ...

Prescient Medical Achieves Milestones in Clinical Studies of vProtect(TM) Luminal Shield

100% Technical Success, No Peri-procedural Complications Reported With Coronary Device DOYLESTOWN, Pa., March 4 /PRNewswire/ -- Prescient Medical, Inc. reached a crucial milestone in February by completing the enrollment of 30 patients in the first phase of its first-in-human clinical trial f...

Patient Receives vProtect(TM) Luminal Shield in First-Ever Vulnerable Plaque Clinical Trial

Prescient Medical - SECRITT I Study to Evaluate Preventive Treatment of Potentially Life Threatening Vulnerable Plaques ROTTERDAM, Netherlands and DOYLESTOWN, Pa., June 30 /PRNewswire/ -- An interventional cardiology team led by Professor Patrick W. Serruys successfully placed a vPr...

Prescient Medical, Inc. Achieves Successful Clinical Debut of vProtect(TM) Luminal Shield

Novel self-expanding intracoronary prosthesis successfully placed in three patients with coronary artery disease DOYLESTOWN, Pa., May 29 /PRNewswire/ -- Three patients with established cardiac ischemia recently became the first recipients of the vProtect Luminal Shield, a self-e...

Prescient Medical, Inc. Acquires New Technology to Detect Inflammation in Coronary Blood Vessels

...ral other revolutionary diagnostic and treatment approaches in 2008. This will include the first human clinical studies of the stent-like vProtect(TM) luminal Shield, a prosthesis that treats soft coronary plaques, and the vPredict(TM) Optical Catheter System, a diagnostic catheter designed to analyze and qu...
Luminal in Medical Products

Webster Luminal Decapolar (Coronary Sinus Fixed Curve Catheters)

Description: Biosense Webster is the source for a complete line of diagnostic coronary sinus catheters for left-sided mapping - all with the quality, reliability and precise performance you've come to expect from the leader in catheter technology. All of our coronary sinus catheters are specifically designed an...
Company:Biosense Webster, a Johnson & Johnson Company

MULTI-LINK MINI VISIONCoronary Stent System

Description:...el treatment. The Guidant MULTI-LINK MINI VISION RX and Guidant MULTI-LINK MINI VISION OTW Coronary Stent Systems are indicated for improving coronary luminal diameter in patients with abrupt or threatened abrupt closure with failed interventional therapy of de novoand restenotic native coronary artery lesio...
Company:Guidant Corporation

GORE-TEX INTERING Vascular Graft-Revision Stretch

Description:...d, unibody construction, the GORE-TEX INTERING Vascular Graft is the lowest profile, radially supported graft available today. The graft has a smooth, luminal surface that's soft to the touch, and yet is exceptionally strong. It resists kinking and compression, thanks to an all-PTFE, no-profile radial suppor...
Company:W. L. Gore & Associates, Inc.

GORE-TEX® INTERING Vascular Graft-Standard Walled

Description:...ibody construction, the GORE-TEX® INTERING Vascular Graft is the lowest profile, radially supported graft available today. The graft has a smooth, luminal surface that's soft to the touch, and yet is exceptionally strong. It resists kinking and compression, thanks to an all-PTFE, no-profile radial suppor...
Company:W. L. Gore & Associates, Inc.

GORE-TEX INTERING Vascular Graft-Standard Walled Stretch

Description:...d, unibody construction, the GORE-TEX INTERING Vascular Graft is the lowest profile, radially supported graft available today. The graft has a smooth, luminal surface that's soft to the touch, and yet is exceptionally strong. It resists kinking and compression, thanks to an all-PTFE, no-profile radial suppor...
Company:W. L. Gore & Associates, Inc.

GORE-TEX INTERING Vascular Graft-Peripheral Thin Walled Stretch

Description:...d, unibody construction, the GORE-TEX INTERING Vascular Graft is the lowest profile, radially supported graft available today. The graft has a smooth, luminal surface that's soft to the touch, and yet is exceptionally strong. It resists kinking and compression, thanks to an all-PTFE, no-profile radial suppor...
Company:W. L. Gore & Associates, Inc.

TAXUS Express2 Monorail Paclitaxel-Eluting Coronary Stent System

Description:... The TAXUS Express Paclitaxel-Eluting Coronary Stent System is indicated for improving luminal diameter for the treatment of de novo lesions = 28 mm in length in native coronary arteries = 2.5 to = 3.75 mm in diameter....
Company:Boston Scientific Corporation

TAXUS Express2 Over-the-wire Paclitaxel-Eluting Coronary Stent System

Description:... The TAXUS Express Paclitaxel-Eluting Coronary Stent System is indicated for improving luminal diameter for the treatment of de novo lesions = 28 mm in length in native coronary arteries = 2.5 to = 3.75 mm in diameter....
Company:Boston Scientific Corporation

MULTI-LINK RX PENTA Coronary Stent System

Description:... The MULTI-LINK RX PENTA Coronary Stent Systems with new ACCESS-LINK Stent Design are indicated for improving coronary luminal diameter....
Company:Guidant Corporation

MULTI-LINK OTW PENTA Coronary Stent System

Description:... The MULTI-LINK RX PENTA Coronary Stent Systems with new ACCESS-LINK Stent Design are indicated for improving coronary luminal diameter....
Company:Guidant Corporation
Luminal in Biological News

Stem cell 'daughters' lead to breast cancer

...ave found that a population of breast cells called luminal progenitor cells are likely to be responsible for ...esearch Consortium Laboratory have discovered that luminal progenitor cells the 'daughters' of breast stem c...h BRCA1 mutations has unexpectedly high numbers of luminal progenitor cells," she said. "Further, our gen...

UNC study identifies genetic cause of most common form of breast cancer

...leagues specifically targeted the role that p18 plays in the development of luminal breast cancers. Using genetically-engineered mice with deletion of p18 gen...sed expression of the p18 gene is highly correlated with the development of luminal tumors. "The mechanism behind these tumors is quite different from that ...

GEN reports on strategies to overcome blood-brain barrier

...h factor (IGF), leptin, transferrin, and low-density lipoprotein (LDL). In RMT, molecules in the circulation may bind to specific receptors on the luminal surface of brain capillaries (i.e., the surface that interfaces with the bloodstream). Upon binding, the receptor-ligand complex is internalized into ...

Simulations unravel outer membrane transport mechanism

...cules can pass. Another region of the protein, the luminal domain, clogs this barrel until the cell is ready ...tudies had shown that TonB binds to one end of the luminal domain. Researchers had hypothesized that TonB somehow draws the luminal domain out of the barrel or changes its conformati...

Clues to breast cancer hidden inside stem cells

... form during pregnancy. "This caught our attention, and has driven our research," Sigurdsson pointed out. Breast cancer almost always occurs in the luminal epithelial compartment, which is also where milk is produced. Perhaps it is not surprising then, that stem cells reside in this compartment. In 2002,...

Study reveals dramatic difference between breast cancers in US and Africa

...ficant differences: -- First, breast cancers in African women were more likely to arise from basal-like cells, rather than the inner milk-secreting luminal cells, which are the most common source of breast cancers for U.S. and European women. (This type of basal-like breast cancer is also observed among w...
Luminal in Biological Technology

vProtect(TM) Luminal Shield Stabilizes Life-Threatening Plaque

Healthy Vessel Seen in 6-Month Follow-up Exam on First Patient to Receive Preventive Treatment for Vulnerable Plaque ROTTERDAM, Netherlands and DOYLESTOWN, Pa., Jan. 15 /PRNewswire/ -- The first patient receiving focal preventive treatment for vulnerable plaque recently underwent a 6-month f...

Tigris Pharmaceuticals Presents Results of Breast Cancer Research at AACR Annual Meeting

...ara Ann Karmanos Cancer Institute and professor of Pharmacology at Wayne State University School of Medicine in Detroit. The research found that the luminal (ER-positive) and the triple negative (ER, PR, and HER-2 negative) breast cancer cell lines with the basal A gene profile subtype were very sensitive ...

Clarient Granted Exclusive License to Commercialize Breast Cancer Biomarker by Indiana University Research and Technology Corporation

...ts of breast cancer characteristics, which include luminal A and B subtypes," said Ken Bloom, M.D., Clarient'...stic significance," Dr. Bloom said. "Although both luminal subtype A and B correspond to ER-positive breast cancers, we have always known that luminal A subtype patients are associated with a significa...

Prescient Medical, Inc. to Present Data on Identification and Treatment of Rupture-Prone Coronary Plaques at EuroPCR 2008

...t(TM) Optical Catheter System and the vProtect(TM) luminal Shield, at the upcoming EuroPCR 2008 conference to...Barcelona, Spain from May 13 to 16. The vProtect luminal Shield was designed by Prescient Medical to treat ...nt for coronary artery disease (CAD). The vProtect luminal Shield has been designed to limit complications co...

Differential Gene Expression Analysis of Pure Cell Populations from Frozen UterineTissue Using Laser Capture Microdissection (LCM) and cDNA Microarrays

...um and myometrium. The endometrium is comprised of luminal epithelium, densely packed stroma, and the germina...ical uterine contact with the maternal endometrial luminal epithelium. In previous analyses of global gene ex...l population. 1,2 Using LCM, a pure population of luminal epithelial tissue was obtained, without stromal ce...
Luminal in Biological Products

Mouse Anti-Human Embryonal Carcinoma Ab-1 Monoclonal Antibody, Unconjugated, Clone 4C4 from Lab Vision

Description:...a of testis and ovary but not other type of germ cell tumors like seminoma. Glandular epithelium of yolk sac tumor and immature teratoma are positive. luminal and endocrine cells of stomach and acini cells of pancreas and lobules of breast are also positive. Epitope: Carbohydrate portion on human embryonal...
Company:Lab Vision
Luminal in Biological Dictionary

Anchor Sequence

...amilies yielded anchor sequences that ... MITE elements indicate similar sequence blocks on MITEs to the anchor . elements. ... ... of the luminal juxtamembrane hydrophobic sequence (aa 717 to 747), TM anchor ... that aa 751 to 771 function as the TM anchor sequence of gB and that derivat...
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