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Lubiprostone in Medical News

New Guidelines Issued for Management of IBS

...n larger numbers of people is evaluated. Psychological counseling may also provide some relief. Selective C-2 chloride channel activators, notably lubiprostone (Amitiza), are effective for "constipation-predominant IBS." 5HT 3 antagonists such as alosetron (Lotronex) relieve symptoms of diarrhea but can c...

Drug brings relief for many IBS patients who experience constipation

...ogist William D. Chey, M.D., the studies show that lubiprostone significantly improves all of the symptoms associa...nvolving 1,154 participants. These trials compared lubiprostone versus a placebo during the course of 12 weeks. Ea...-C symptoms. After one week, 20 percent of the lubiprostone participants reported moderate to significant reli...

Silence Puts Comfort For Digestive Syndrome

...elabeled in 2004 to warn of a rare, serious side effect involving low blood pressure. IBS patients whose primary symptom is constipation, can take lubiprostone (Amitiza), which was approved in January for the treatment of chronic constipation in adults. Dr. Robert Sandler, vice president of the American s...

New compounds Help Sustain relief For Patients With Symptoms of Bowel Disorders

...Ranging, Double-Blind, Placebo-Controlled Study of lubiprostone in Subjects with Irritable Bowel Syndrome and Cons...tinal system. This study tested different doses of lubiprostone over 12 weeks in subjects with constipation-specif... four treatment groups: placebo or 16, 32 or 48 μg lubiprostone daily. Patients were asked to keep a log of their ...
Lubiprostone in Medical Technology

Sucampo Pharmaceuticals, Inc. Begins Pivotal Phase III Studies of Oral Lubiprostone to Treat Opioid-Induced Bowel Dysfunction (OBD)

First Patient Enrolled in Pivotal Studies BETHESDA, Md., Sept. 13 /PRNewswire-FirstCall/ -- Sucampo Pharmaceuticals, Inc. (Nasdaq: SCMP ) and Takeda Pharmaceuticals North America, Inc. today announced that the first patient has been enrolled in a Phase III study of lubiprostone...

New Study Demonstrates that Lubiprostone May Improve Symptom Relief Rates in Adults with Irritable Bowel Syndrome with Constipation (IBS-C)

WASHINGTON, May 21, 2007 /PRNewswire/ -- A new study demonstrated that the active ingredient in Amitiza (lubiprostone), given 8 mcg twice a day, may improve symptom relief rates in adults with irritable bowel syndrome with constipation (IBS-C). These results were presented as a late-breaker at Dig...

New Study Shows Probiotic Strain Effective in Improving Irritable Bowel Syndrome Symptoms

..., are FDA-approved only for certain types of IBS: alosetron is for women with severe IBS-related diarrhea only and has serious potential side effects; lubiprostone is only for women with IBS-related constipation. Doctors commonly recommend over-the-counter medications such as laxatives, antidiarrheals, and bulki...

New AMITIZA 8 mcg Phase III Studies Demonstrated Overall Symptom Improvement in Adult Women with Irritable Bowel Syndrome with Constipation (IBS-C)

... Oral; Sunday, May Improvement with lubiprostone in 18, 2008 at 3:00pm Patients ...d, Placebo- controlled Trials S1272 lubiprostone is Effective and Well Poster; Sunday, May ... presentation from Studies with lubiprostone 12pm-2pm PDT M1706 Discontinu...
Lubiprostone in Biological Technology

FDA Accepts Sucampo's sNDA for Lubiprostone (8 mcg) for the Treatment of Irritable Bowel Syndrome with Constipation (IBS-C)

Lower Strength of Approved Constipation Drug Offers Potential Treatment Option to Americans Suffering from IBS-C BETHESDA, Md., Sept. 17 /PRNewswire-FirstCall/ -- Sucampo Pharmaceuticals, Inc., (Nasdaq: SCMP ) today announced that the supplemental New Drug Application (sNDA) fo...

'Move to AMITIZA' Advertising Campaign Underscores the Power of Not Letting Chronic Constipation Slow People Down

...ce of such an obstruction prior to initiating AMITIZA treatment. The safety of AMITIZA in pregnancy has not been evaluated in humans. In guinea pigs, lubiprostone has been shown to have the potential to cause fetal loss. AMITIZA should be used during pregnancy only if the benefit justifies the potential risk to ...
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