New Guidelines Issued for Management of IBS
...n larger numbers of people is evaluated. Psychological counseling may also provide some relief. Selective C-2 chloride channel activators, notably lubiprostone (Amitiza), are effective for "constipation-predominant IBS." 5HT 3 antagonists such as alosetron (Lotronex) relieve symptoms of diarrhea but can c...Drug brings relief for many IBS patients who experience constipation
...ogist William D. Chey, M.D., the studies show that lubiprostone significantly improves all of the symptoms associa...nvolving 1,154 participants. These trials compared lubiprostone versus a placebo during the course of 12 weeks. Ea...-C symptoms. After one week, 20 percent of the lubiprostone participants reported moderate to significant reli...Silence Puts Comfort For Digestive Syndrome
...elabeled in 2004 to warn of a rare, serious side effect involving low blood pressure. IBS patients whose primary symptom is constipation, can take lubiprostone (Amitiza), which was approved in January for the treatment of chronic constipation in adults. Dr. Robert Sandler, vice president of the American s...New compounds Help Sustain relief For Patients With Symptoms of Bowel Disorders
...Ranging, Double-Blind, Placebo-Controlled Study of lubiprostone in Subjects with Irritable Bowel Syndrome and Cons...tinal system. This study tested different doses of lubiprostone over 12 weeks in subjects with constipation-specif... four treatment groups: placebo or 16, 32 or 48 μg lubiprostone daily. Patients were asked to keep a log of their ...New Study Shows Probiotic Strain Effective in Improving Irritable Bowel Syndrome Symptoms
..., are FDA-approved only for certain types of IBS: alosetron is for women with severe IBS-related diarrhea only and has serious potential side effects; lubiprostone is only for women with IBS-related constipation. Doctors commonly recommend over-the-counter medications such as laxatives, antidiarrheals, and bulki...