New Guidelines Issued for Management of IBS
...n larger numbers of people is evaluated. Psychological counseling may also provide some relief.
Selective C-2 chloride channel activators, notably lubiprostone
(Amitiza), are effective for "constipation-predominant IBS."
5HT 3 antagonists such as alosetron (Lotronex) relieve symptoms of diarrhea but can c...
Drug brings relief for many IBS patients who experience constipation
...ogist William D. Chey, M.D., the studies show that lubiprostone
significantly improves all of the symptoms associa...nvolving 1,154 participants. These trials compared lubiprostone
versus a placebo during the course of 12 weeks. Ea...-C symptoms.
After one week, 20 percent of the lubiprostone
participants reported moderate to significant reli...
Silence Puts Comfort For Digestive Syndrome
...elabeled in 2004 to warn of a rare, serious side effect involving low blood pressure.
IBS patients whose primary symptom is constipation, can take lubiprostone
(Amitiza), which was approved in January for the treatment of chronic constipation in adults.
Dr. Robert Sandler, vice president of the American s...
New compounds Help Sustain relief For Patients With Symptoms of Bowel Disorders
...Ranging, Double-Blind, Placebo-Controlled Study of lubiprostone
in Subjects with Irritable Bowel Syndrome and Cons...tinal system. This study tested different doses of lubiprostone
over 12 weeks in subjects with constipation-specif... four treatment groups: placebo or 16, 32 or 48 μg lubiprostone
daily. Patients were asked to keep a log of their ...
Lubiprostone in Medical Technology
Sucampo Pharmaceuticals, Inc. Begins Pivotal Phase III Studies of Oral Lubiprostone to Treat Opioid-Induced Bowel Dysfunction (OBD)
First Patient Enrolled in Pivotal Studies
BETHESDA, Md., Sept. 13 /PRNewswire-FirstCall/ -- Sucampo
Pharmaceuticals, Inc. (Nasdaq: SCMP ) and Takeda Pharmaceuticals North
America, Inc. today announced that the first patient has been enrolled in a
Phase III study of lubiprostone...
New Study Demonstrates that Lubiprostone May Improve Symptom Relief
Rates in Adults with Irritable Bowel Syndrome with Constipation
WASHINGTON, May 21, 2007 /PRNewswire/ -- A new study
demonstrated that the active ingredient in Amitiza (lubiprostone),
given 8 mcg twice a day, may improve symptom relief rates in adults
with irritable bowel syndrome with constipation (IBS-C). These
results were presented as a late-breaker at Dig...
New Study Shows Probiotic Strain Effective in Improving Irritable Bowel Syndrome Symptoms
..., are FDA-approved only for certain types of IBS: alosetron is for women with severe IBS-related diarrhea only and has serious potential side effects; lubiprostone
is only for women with IBS-related constipation. Doctors commonly recommend over-the-counter medications such as laxatives, antidiarrheals, and bulki...
New AMITIZA 8 mcg Phase III Studies Demonstrated Overall Symptom Improvement in Adult Women with Irritable Bowel Syndrome with Constipation (IBS-C)
... Oral; Sunday, May Improvement with lubiprostone
in 18, 2008 at 3:00pm Patients ...d, Placebo- controlled Trials
is Effective and Well Poster; Sunday, May ... presentation from Studies with lubiprostone
Lubiprostone in Biological Technology