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Localize in Medical News

Scientists use nanomaterials to localize and control drug delivery

Using nanotechnology, scientists from UCLA and Northwestern University have developed a localized and controlled drug delivery method that is invisible to the immune system, a discovery that could provide newer and more effective treatments for cancer and other diseases. The study, published J...

Brookhaven Lab and Hybridyne Imaging Technologies Inc., win R&D 100 award

...g a compact gamma camera for high-resolution imaging of prostate cancer. The camera system, called ProxiScan, is a nuclear medical instrument that can localize cancer tissue in the prostate gland in detail at an early stage, which is important for the successful diagnosis and early treatment of the potentiall...

European Medicines Agency (EMEA) Approves Cell Therapeutics, Inc.'s September Meeting Request to Discuss OPAXIO(TM) Marketing Authorization Application

...ntially distributed to tumors due to their leaky blood vessels and trapped in the tumor bed allowing significantly more of the dose of chemotherapy to localize in the tumor than with standard paclitaxel. Once inside the tumor cell, enzymes metabolize the protein polymer, releasing the paclitaxel chemotherapy....

Set Up Your Computer to Work in Another Language – New Tips at Argotrans.com

...re effectively across languages,” said Peter Argondizzo, president of Argo Translation. “Sometimes that’s helping them translate or localize their products or media content while at other times we’re just giving them - tips and advice on how to operate more effectively in other langua...

Faster, better diagnosis for patients with heart rhythm disorders

...quipment allows us to better visualize electrical activity in the heart and localize the source of rhythm disturbance," says Dr. Eugene Downar, cardiologist in ... in the heart which are displayed on a screen and help electrophysiologists localize the source of the abnormal heart rhythm. "Visualizing the catheters in t...

University of Notre Dame Chooses Latest Technology From Carestream Molecular Imaging For Disease Research

...odal capability," he added. "The system's X-ray mode provides a convenient anatomical map with which to precisely co-register and accurately localize optical or radioisotopic signals emanating from target disease cells. This is an extremely powerful and useful combination." Notre Dame&rsquo...

Kidney Care Partners Raises Alarm on Racial Disparities in Kidney Disease; Joins With National Minority Quality Forum to Educate Public, Congress During National Kidney Month

...reventable illness in racial and ethnic minorities and other special populations. "Our partnership with Kidney Care Partners will enable us to localize data on Chronic Kidney Disease (CKD) prevalence and End-Stage Renal Disease (ESRD) incidence by various cohorts, identify trends, and forecast risk." ...

CTI Focuses on Late-Stage Drug Approvals and Commercialization and Cuts Operating Costs: to Close Bresso Research Center

...ntially distributed to tumors due to their leaky blood vessels and trapped in the tumor bed allowing significantly more of the dose of chemotherapy to localize in the tumor than with standard paclitaxel. Once inside the tumor cell, enzymes metabolize the protein polymer, releasing the paclitaxel chemotherapy...

Bio-imaging mass spectrometry techniques reveal molecular details about complex systems

...rushing. Using histological samples provided by Timothy Cox, a professor of medicine at the University of Cambridge, the researchers could profile and localize many different lipid species in the samples. Specifically, they localized sphingolipids that accumulate in the brain when there is a genetic defect. T...

Cancer research highlights

...T/PET breast scanner would allow clinicians to, among other uses, precisely localize and monitor the response of a tumor to chemotherapy, determine the extent (...s an image of the 3D distribution of metabolic activity. To help physically localize the source, a dedicated breast CT scan, also developed in Tornai's lab, wit...
Localize in Medical Technology

OPAXIO(TM) Combined with Alimta(R) Well Tolerated in Dose-Ranging Study of Patients with Advanced Non-Small Cell Lung Cancer

...ntially distributed to tumors due to their leaky blood vessels and trapped in the tumor bed allowing significantly more of the dose of chemotherapy to localize in the tumor than with standard paclitaxel. Once inside the tumor cell, enzymes metabolize the protein polymer, releasing the paclitaxel chemotherapy....

Paclitaxel Poliglumex (OPAXIO(TM)) Added to Cisplatin and Radiation Produces 45% Pathologic Complete Remissions in Patients With Esophageal Cancer

...ntially distributed to tumors due to their leaky blood vessels and trapped in the tumor bed allowing significantly more of the dose of chemotherapy to localize in the tumor than with standard paclitaxel. Once inside the tumor cell, enzymes metabolize the protein polymer, releasing the paclitaxel chemotherapy....

European Regulatory Agency Accepts Cell Therapeutics, Inc.'s Marketing Authorization Application for XYOTAX(TM) for Lung Cancer for Review

...ntially distributed to tumors due to their leaky blood vessels and trapped in the tumor bed allowing significantly more of the dose of chemotherapy to localize in the tumor than with standard paclitaxel. Once inside the tumor cell, enzymes metabolize the protein polymer, releasing the paclitaxel chemotherapy....

Cell Therapeutics, Inc. (CTI) Submits European Marketing Authorization Application for XYOTAX(TM)

...ntially distributed to tumors due to their leaky blood vessels and trapped in the tumor bed allowing significantly more of the dose of chemotherapy to localize in the tumor than with standard paclitaxel. Once inside the tumor cell, enzymes metabolize the protein polymer, releasing the paclitaxel chemotherapy....

Semafore's SF1126 Exhibits Antitumor and Antiangiogenic Activity

...uding prostate, breast, neuroblastoma, and glioblastoma. SF1126 differs from other known PI3K inhibitors in that it has a homing feature designed to localize more drug in the tumor compartment. Based on the studies reported in the paper, SF1126 also significantly enhanced the activity of docetaxel in a comb...

Cell Therapeutics, Inc. (CTI) Supports Panel Discussion on Women and Lung Cancer on Capitol Hill

...ntially distributed to tumors due to their leaky blood vessels and trapped in the tumor bed allowing significantly more of the dose of chemotherapy to localize in the tumor than with standard paclitaxel. Once inside the tumor cell, enzymes metabolize the protein polymer, releasing the paclitaxel chemotherapy....

Cell Therapeutics, Inc. (CTI) Sponsors Panel Discussion on Women and Lung Cancer on Capitol Hill

...ntially distributed to tumors due to their leaky blood vessels and trapped in the tumor bed allowing significantly more of the dose of chemotherapy to localize in the tumor than with standard paclitaxel. Once inside the tumor cell, enzymes metabolize the protein polymer, releasing the paclitaxel chemotherapy....

XYOTAX More Cost Effective With Fewer Side Effects Than Gemcitabine or Vinorelbine in Treating Non-Small Cell Lung Cancer

...ntially distributed to tumors due to their leaky blood vessels and trapped in the tumor bed allowing significantly more of the dose of chemotherapy to localize in the tumor than with standard paclitaxel. Preclinical and clinical studies support that XYOTAX metabolism by lung cancer cells may be influenced by ...
Localize in Medical Products

OmniSight™ EXcel System: Image-Guided Surgery

Description:...ured image guidance while maintaining simplicity in design and use. It provides unparalleled three-dimensional visualization, allowing the surgeons to localize critical anatomy and plan optimal surgical trajectories. This new system gives surgeons an easy-to-use, technologically advanced approach to surgical ...
Company:Integra Radionics, Inc.

Dornier Lithotripter S II

Description:...ple. This is accomplished by adding the optional ultrasound system with X-ray during stone therapy. The X-ray function can be used to pre-position and localize the stone before switching to ultrasound to monitor the treatment progress....
Company:Dornier MedTech

OmniSight image guided surgery system with Calyx 2 Fluoroscopic Tracking Module

Description:... image guidance while maintaining simplicity in design and use. It provides unparalleled three-dimensional visualization, allowing the neurosurgeon to localize critical anatomy and plan optimal surgical trajectories. This new system gives surgeons an easy-to-use, technologically advanced approach to surgical ...
Company:Integra Radionics, Inc.

OmniSight Image Guided Surgery System

Description:... image guidance while maintaining simplicity in design and use. It provides unparalleled three-dimensional visualization, allowing the neurosurgeon to localize critical anatomy and plan optimal surgical trajectories. This new system gives surgeons an easy-to-use, technologically advanced approach to surgical ...
Company:Integra Radionics, Inc.

Implant Stabilizer

Features:... Adjustable Velcro® straps allow the doctorto localize the implants to achieve the desired appearance, shape and to correctly position the breast implants after surgery....
Company:Contemporary Design Inc.

Novalis

Features:...lis Body features image-guided radiosurgery for high precision treatment of body targets. Its X-ray-based localization technology allows physicians to localize tumors with sub-millimeter accuracy and to position patients automatically and with a higher degree of precision than previously possible. With Novali...
Company:BrainLAB Inc.

TC 22

Features:...flow of the entire exam as you define it, making advancements from one signal to the next as simple as a button push. The new search feature helps you localize the best signal even in the toughest of patients....
Company:SciMed Limited
Localize in Medical Dictionary

In situ

...ted States. In situ hybridization, also referred to a hybridization histochemistry, was ... Using in situ hybridization, it is possible to localize gene expression to ... in situ DESIGN Therefore, the in situ gene conservation strategies and methods developed ... selection of t...
Localize in Biological News

Reprogramming human cells without inserting genes

...vation," said Raymond Page, PhD, research assistant professor of biology and biotechnology at WPI and lead author on the paper. "Having these proteins localize to the nucleus is the first step of reprogramming these cells." Even more surprising, the team found that the stem cell genes OCT4, SOX2 and NANOG ...

Spontaneous assembly

...al proteins. "Since individual proteins are imaged one at a time, we can localize and count them, and then computationally assemble the locations of all prot...embrane. "Chemotaxis proteins cluster into large sensory complexes that localize to the poles of the bacterial cell," Liphardt said. "We wanted to understan...

Manatees can probably hear which directions boats approach from

...atees perceive their environment. Whether they can localize sounds, and specifically whether they can tell whi...rd these sounds. So how are the animals able to localize sounds? Colbert explains that many terrestrial ani... combinations of these and other cues to help them localize sounds, as they were able to locate the sources of...

Researchers develop flow sensors based on hair structures of blind cavefish

... researchers to mimic the hairs of these blind cavefish in the laboratory. While the fish use these hairs to detect obstacles, avoid predators and localize prey, researchers believe the engineered sensors they are developing could have a variety of underwater applications, such as port security, surveilla...

Lipid droplets lead a Spartin existence

...1 removed Spartin from LDs and promoted its degradation. A truncated form of Spartin found in a rare neuronal disease called Troyer syndrome didn't localize to LDs or bind to TIP47. It remains to be seen whether defects in LD function are the root cause of the defects seen in Troyer patients, but author Pa...

CSHL researchers pinpoint structure-building role for 2 non-coding RNAs

...nto the cell's cytoplasm like their protein-coding RNA cousins. ncRNAs localize to paraspeckles Cells usually increase their production of ncRNAs when ..."One way to figure out hints as to what ncRNAs do is to find out where they localize within cells, which might reveal the molecules they interact with and the p...

Engineers create intelligent molecules that seek-and-destroy diseased cells

... that trigger cell death only in the presence of such markers. "A lot of the trick with developing effective therapeutics is the ability to target and localize the therapeutic effect, while minimizing nonspecific side effects," she said. Smolke will present the latest applications of her lab's work at the ...

Billion-year revision of plant evolution timeline may stem from discovery of lignin in seaweed

...nal Current Biology , lead author Patrick Martone and colleagues describe using powerful chemical and microscopic anatomy techniques to identify and localize lignin within cell walls of a red alga that thrives along the wave-swept California coast. Martone conducted the work described in the paper while a g...

Risk and reward compete in brain

...f the interaction between two brain regions. Co-author Zhong-Lin Lu, professor of psychology at USC, said: "What this study has done is essentially localize two separate centers for the fear of risk and the lure of reward." ...

FBI unveils science of anthrax investigation

...roanalysis in the SEM is not a surface-sensitive tool," says Kotula. "Because a spore body can be 1.5 to 2 microns wide by 1 micron long, a SEM cannot localize the elemental signal from whole spore bodies." Using more sensitive transmission electron microscopy (TEM), Kotula and Michael's research indicated...
Localize in Biological Technology

University of Maryland Announces Finalists for $75K Business Plan Competition

...any will design and build micro-power plants using renewable energy sources available in the communities, while also establishing processing plants to localize value-added services for the region's raw materials. The power plant and the processing plant will be linked and interdependent, with the electricity ...

Mindray Announces 2008 Fourth Quarter and Full Year Results

...price products to an increasingly cost-conscious customer base. In addition, to improve our international distribution platform, we plan to expand and localize our international distribution teams at reasonable costs. Mindray is well positioned to navigate these unprecedented times and to capitalize on any op...

FBI unveils science of anthrax investigation

...roanalysis in the SEM is not a surface-sensitive tool," says Kotula. "Because a spore body can be 1.5 to 2 microns wide by 1 micron long, a SEM cannot localize the elemental signal from whole spore bodies." Using more sensitive transmission electron microscopy (TEM), Kotula and Michael's research indicated...

Health Robotics Announces Strategic Partnership in Japan for its CytoCare(TM) Robot with TOSHO Inc.

...rvice provider in Japan. The companies will jointly implement CytoCare(TM) at TOSHO's Oncology-focused customers in Japan and have agreed to adapt and localize Health Robotics' software applications for the Japanese market. "We are very pleased to have been selected by Health Robotics as their exclusive par...

Clontech Laboratories, Inc. Recognizes the 2008 Winners of the Nobel Prize in Chemistry

...tionized life science research and biotechnology: they enable researchers to monitor cellular activity in real time, characterize gene expression, and localize specific proteins, organelles, or cells of interest. Thus, fluorescent proteins have facilitated many groundbreaking discoveries in cell biology over ...

FBI unveils science of anthrax investigation

...roanalysis in the SEM is not a surface-sensitive tool," says Kotula. "Because a spore body can be 1.5 to 2 microns wide by 1 micron long, a SEM cannot localize the elemental signal from whole spore bodies." Using more sensitive transmission electron microscopy (TEM), Kotula and Michael's research indicated...

/R E P E A T -- Oncolytics Biotech Inc. Announces U.S. Phase 2 Combination Clinical Trial for Non-Small Cell Lung Cancer Patients with K-RAS or EGFR-Activated Tumours/

...roup. This study targets patients with either EGFR-activated tumours or K-RAS mutations. "Previous preclinical data indicates that reovirus tends to localize in the lungs, and we have seen clinical responses in metastatic lung lesions with REOLYSIN(R) as a monotherapy or in combination with paclitaxel and c...

Oncolytics Biotech Inc. Announces U.S. Phase 2 Combination Clinical Trial for Non-Small Cell Lung Cancer Patients with K-RAS or EGFR-Activated Tumours

...roup. This study targets patients with either EGFR-activated tumours or K-RAS mutations. "Previous preclinical data indicates that reovirus tends to localize in the lungs, and we have seen clinical responses in metastatic lung lesions with REOLYSIN(R) as a monotherapy or in combination with paclitaxel and c...

John Grisham Joins Focused Ultrasound Surgery Foundation Board, Citing Novel Technology's Potential to Help 'Millions of Patients'

... delivery, or liquification of blood clots. Magnetic resonance imaging is used to visualize normal anatomy and abnormal structures within the body, to localize the tissue to be targeted, to guide and control the treatment interactively, and to evaluate the effectiveness of therapy. About The Focused Ultraso...

New kind of MRI enables study of magnets for computer memory

...y the new technique works. Every atom emits radio waves at a particular frequency. But to know where those atoms are, scientists need to be able to localize where the radio waves are coming from. Large-scale MRI machines, such as those in hospitals, get around this problem by varying the magnetic field ...
Localize in Biological Products

Imaging Mass Spectrometry for Small Molecule Localization from Protein Discovery, Inc.

Description:...sing mass spectrometry. Protein Discoverys imaging mass spectrometry service maps unlabeled ions and aligns them with histological images so you can localize drugs and metabolites prior to synthesizing radiolabeled compound. Imaging mass spectrometry enables cell type specific analysis without microdissecti...
Company:Protein Discovery, Inc.
Localize in Biological Definition

Tubulin

...owever, the prokaryotic cell division protein FtsZ was shown to be evolutionarily related to tubulin. Delta and epsilon tubulin have been found to localize at centrioles and may play a role in forming the mitotic spindle during mitosis. Pharmacology Tubulins are targets for anticancer drugs lik...
Localize in Biological Dictionary

Localize

National varieties of languages (see language localization ) ... http://blog.i18n.ro/are-we -supposed-to- localize -keyboard -shortcuts ... localize ( ) v. , -ized , -izing , -izes . v.tr. To make local: decentralize and localize political authority ... difference between localize ...

Nucleoli

...ied from the genomic ribosomal RNA genes into ... Several individual nucleoli are shown in each differential interference contrast ... snoRNAs localize to nucleoli in RanGAP (rna1-1) mutant cells. ... ... one, two, or more apparently normal nucleoli in addition to the four which are ... The pr...

In situ hybridization

...on that uses a labeled complementary DNA or RNA strand (i.e., probe) to localize a specific DNA or RNA sequence in a portion or section of tissue ( i...ectly well for ... Using in situ hybridization , it is possible to localize gene expression to ... The first step of in situ hybridization i...

Germline

...hild. 3 Germ line development in mammals. 4 Differentiation of primordial germ cells ... These genes play a role in germ line development to localize nanos mRNA to the ... 3. L1-L3: germline proliferation, survival and differentiation. 4. Late larval and adult stages: germline proliferatio...

DNA probes

... nucleic acid ( DNA or RNA) whose base sequence allows probe-target base pairing due... FISH is a cytogenetic technique used to detect and localize the presence or absence of specific DNA sequences on chromosomes. FISH uses fluorescent probes that bind to only those parts of the chromosome ...

Cytochromes

...0 and c552 and to the cbb3 ... To examine whether the outer membrane (OM) cytochromes of MR-1 play a role in Mn ... lost the ability to properly localize multiple OM cytochromes to the OM. ... ... bioelectrical circuit are mostly iron-containing proteins called cytochromes . Chemist Kenneth S. ...
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