HRT Raises Risk of Lobular Breast Cancer
Incidence increased with popularity of hormone therapy, study finds WEDNESDAY, Jan. 16 (HealthDay News) -- Not only does hormone replacement therapy raise the risk of breast cancer in postmenopausal women, it really raises the risk of a specific type of malignancy: lobular breast cance...Combined HRT increases risk of lobular breast cancer fourfold after just 3 years of use
SEATTLE Postmenopausal women who take combined estrogen/progestin hormone-replacement therapy for three years or more face a fourfold increased risk of developing various forms of lobular breast cancer, according to new findings by researchers at Fred Hutchinson Cancer Research Center. Previous ...Gene Warfare and Lobular Cancer
Every one in ten or fifteen cases of breast cancer can be attributed to Classic Lobular Carcinomas (CLC).// Breast tissue is made up of ducts or tubes and lobules( milk producing glands). Invasive(spreading) lobular cancer can occur in women of the age group 45 to 55. As the symptoms of th...Atypical Lobular Hyperplasia increases risk of breast cancer
Researchers in Tennessee who studied 7600 women who had a breast biopsy because they had detected a lump, found that women with a condition called atypical lobular hyperplasia went// on to develop invasive breast cancer. Invasive breast cancer is a condition where cancer cells break through the duc...Novel gene predicts local recurrence in early onset breast cancer
...nd evidence that DEAR1 plays a critical regulatory role in acinar morphogenesis, or the orderly development and differentiation of the terminal ductal lobular units (TDLU) in the breast. TDLUs are structures present at the ends of a branching network of ducts in the normal mammary gland which also are thoug...Novel gene predicts local recurrence in early-onset breast cancer
...nd evidence that DEAR1 plays a critical regulatory role in acinar morphogenesis, or the orderly development and differentiation of the terminal ductal lobular units (TDLU) in the breast. TDLUs are structures present at the ends of a branching network of ducts in the normal mammary gland which also are thoug...Drop in Breast Cancer Rates Due to Drop in HRT Use
... cancer, and following them until mid-2005. They found that the risk of breast cancer increased substantially after three years of using HRT -- for lobular cancer, the therapy doubled the risk at three years -- but there was no increased risk for those who used it for less than two years. However, Chlebow...Dual role in breast tissue for a protein involved in leukemia
...receptor-positive as compared to estrogen receptor-negative. When estrogen receptor levels were overexpressed, loss of Stat5a reduced development of a lobular type of preneoplasia. However, when estrogen receptor levels were normal, loss of Stat5a not only had no effect on reducing preneoplasia, but increase...In just 5 years, gene discovery to clinical trial of potential treatment
...cause progerin wreaks havoc, cells become unstable and abnormal. The resulting gross disfigurement of the cell's nucleus is described as "blebbed," or lobular in shape. (Recent research indicates that all people, not just children with HGPS, produce small amounts of progerin, and that this mutant protein ...'New' estrogen receptor found to be key player in tamoxifen resistance
...that the discovery could help explain why invasive lobular carcinoma the sub-type of breast cancer in which...sistance apparently plays in treatment of invasive lobular cancer." Invasive lobular carcinoma, which accounts for 15 percent of newly ...Two nerve cells in direct contact
...the tangential cells of the lobula plate in detail. This was based on a multitude of experiments in which the connections between the cells within one lobular plate and those between the two hemispheres were examined. In the end it turned out that there were two ways in which movement information from one ha...Terahertz imaging may reduce breast cancer surgeries
...t three samples yielded invasive cancers. In total, there were two invasive lobular carcinomas, 14 invasive ductal carcinomas, three mixed invasive ductal and lobular carcinomas, two cases of pure ductal carcinoma in situ and one dense radial...Breast-Specific Gamma Imaging (BSGI) Offers Greater Sensitivity Over Mammography, Ultrasound and MRI
...s Conclusive Findings in the Detection of Invasive lobular Carcinoma NEWPORT NEWS, Va., March 3 /PRNews...ve imaging technique for the diagnosis of invasive lobular carcinoma (ILC) -- a type of breast cancer that be...re classified as positive or negative for invasive lobular carcinoma by experienced breast imagers. Ultrasou...