Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats
Dana-Farber Cancer Institute researchers have identified a molecular mechanism in the liver that explains, for the first time, how consuming foods rich in saturated fats and trans-fatty acids causes elevated blood levels of cholesterol and triglycerides and increases one's risk of heart disease and certain cancers. In the Jan. 28 issue of Cell, scientists led by Bruce Spiegelman, PhD, rep...Research Gives Hope For Liver Damage
Millions of patients suffering from liverdamage (cirrhosis) and failure may benefit from research by theUniversities of Edinburgh and Southampton which may lead to newlife-saving treatments. There is currently no cure for liver cirrhosisand a patient's only hope of survival is to receive a liver transplant.The Edinburgh scientists from the University's Centre for InflammationResearch, in co...New methods of gene delivery using lasers
Leading laser scientists at the University of St Andrews have developed a new method of delivering genes to cells using laser light. The new technique, which is cheap and powerful, could have important implications for future studies in biomedicine and healthcare. Optical technology has huge potential for novel developments in the bio-medical field and St Andrews has outstanding research...Gene Therapy Cures Inherited Liver Disease In Rats
A single dose of gene-virus combination cured rats of a inherited liver disease in which lack of a gene causes the accumulation of bilirubin –which, untreated, results in jaundice and brain damage, said researchers at Baylor College of Medicine in a report in the Proceedings of the Natural Academy of Sciences. "This is the first time this disease (Crigler-Najjar syndrome) has been complete...UNC launches study of liver injury caused by drugs
The University of North Carolina at Chapel Hill is one of five clinical centers nationwide to receive funds from the National Institutes of Health to study why good medications are sometimes bad for the liver. During the next seven years, the Drug-Induced Liver Injury Network, or DILIN, will study patients who have suffered severe liver injury caused by prescription and over-the-counter m...Interspecies Trial Array 2: N Brain, N Liver, N Muscle, N Kidney from CHEMICON
Description:Chemicon Select Tissue Arrays are intended for laboratory research use only. The individual tissues were fixed in neutral buffered formalin and embedded in paraffin. Tissue identification and diagnosis was performed by certified pathologists. Tissue cores were removed from their paraffin blocks and relocated into a new recipient paraffin block, in an array pattern, using Chemicons Advanced Tis...Hep G2 cell line slides ( human: liver; hepatocellular carcinoma ) from GeneTex
Description:Human Hep G2 cells were cultured in Minimum Essential Medium (Eagle) with 2 mM L-glutamine and harvested at the log phase of growth. In order to keep the antigens in their native forms, cells were fixed in acetone-methanol. The cells are arrayed on a 12-well (5 mm) adhesive coated slide, with each wells surface specifically treated to enhance cellular attachment and to minimize background stain...PULSin Protein & Antibody Delivery Reagent from Polyplus Transfection
Description:PULSin is an innovative reagent for highly efficient transfer of functional proteins to the cytoplasm of living cells. Unlike DNA transfection, with PULSin Protein & Antibody Delivery Reagent the amount and timing of exogenous proteins in cells can be controlled, even lethal proteins can now be studied. Real time function blocking and protein localization studies can now be easily performed u...PULSin Protein & Antibody Delivery Reagent from Polyplus Transfection
Description:Protein/antibody delivery using PULSin may be superior to transfection in some applications. For example, unlike traditional transfection, with PULSin you can study lethal proteins and control the level and time course of proteins in cells. Likewise, delivery of blocking antibodies may provide more information than traditional RNA interference experiments. With PULSin you can target in...PULSin Protein & Antibody Delivery Reagent from Polyplus Transfection
Description:Protein/antibody delivery using PULSin may be superior to transfection in some applications. For example, unlike traditional transfection, with PULSin you can study lethal proteins and control the level and time course of proteins in cells. Likewise, delivery of blocking antibodies may provide more information than traditional RNA interference experiments. With PULSin you can target in...pFB-ERV: Retroviral Delivery of the Ecdysone Receptor Proteins
Faster, easier screening for difficult transfections when using thecomplete control kit Stratagene We describe the vector pFB-ERV, an MMLV-based replication-defectiveretroviral vector for delivery of the ecdysone receptor proteins RXR and VgEcR.In stable cell lines infected with an estima...High-Titer Retroviral Vectors for Gene Delivery
High-TiterRetroviral Vectors for Gene Delivery Stratagene The high-titer retroviral vectors pFB and pFB-Neo can be used with anyMoloney Murine L...Unique Enhanced DNA Polymerase Delivers High Fidelity and Great PCR Performance
Improve reliability of PCR reactions with Herculase enhanced DNApolymerase Stratagene enhanced DNApolymerase,* a novel enzyme formulation that providessuperior performance in both routine and demanding PCR applications. Previous...Effectene Transfection Reagent provides efficient gene delivery to primary neuronal cell cultures
Jochen Meier, Ivonne Strmel, Radu Iosub, Sonja Schmidt, and Rosemarie Grantyn Developmental Physiology, Johannes Mller Institute, Humboldt University Medical School (Charit), Berlin, Germany Efficient delivery of DNA to primary neuronal cell cultures is of critical importance...Blood Cells Capable of Regenerating Liver
Livers can be regenerated using stem cells from blood -- an important discovery that means patients may be able to grow their own liver transplants using bone marrow. This adds to a growing body of evidence that stem cells, known as "master cells" because they can produce a variety of different kinds of cells, might one day be manipulated to create custom-grown organ transplants....Laboratory Testing Can Identify Risk of Pre-Term Labor and Delivery
A test for fetal fibronectin can predict whether a pregnant woman is at risk for early labor and delivery. Those at high risk for pre-term births are women with previous pre-term deliveries, those with multiple gestation pregnancy, and those who suffer from diabetes and/or hypertension. The current approach for finding whether a woman will go into premature labor is the use of a clinical scoring...Infant receives first bloodless liver transplant
An Iowa infant aged 7 months was the first recipient of a bloodless liver transplant in Los Angeles, the United States of America. The seven month old, Aiden Michael Rush, whose parents are Jehovah’s Witnesses are prohibited by their religion to receive transfusions. The boy received 20% of his mother’s liver during the transplantation on February 7th at the children’s hospital i...Liver donors can thrive after transplant
Contrary to belief that donating liver can injure the donor, it is now established without doubt that a living person can donate a part of his liver to a person needing it. And the good news is that the donor would continue to live well and thrive after donating part of his/her liver. Donation of a piece of the liver's right lobe from one adult to another is a relatively new procedure. I...Antibiotic induces liver damage in children with E.COLI infections.
The strain of bacteria known as E. coli 0157:H7 causes some of the most serious digestive infections in both children and adults. Infections with this organism are often caused by eating undercooked meat. A major study shows using antibiotics to treat children with E. coli bacterial infection increases the risk of developing a potentially deadly liver disorder. "Our data suggests that an...Topcon IDS-200 Instrument Delivery System
Description:This exciting new product has generated lots of interest, and continues to be one of the most efficient instruments in Ophthalmology and Optometry today. Time Saving benefits any practice. This system can present the auto refractor values directly to the patient. The ultimate in space efficiencyfits comfortably in a 7' X 7' examination room without the need for external projection mirrors....Monarch II IOL Delivery System
Description:Lens Loading and Folding for Multipiece & Single-Piece ACRYSOF Lens with Standard Forceps...Attain™ Deflectable Catheter Delivery System
Description:The Attain™ Deflectable Catheter - designed to be your best option for cannulation using a single catheter. Steerablility - Create a variety of curve shapes during the procedure with a single, steerable guide catheter. Lock the easy-to-use handle mechanism in the desired shape to address each patient's unique anatomy during CS cannulation. Stable, Versatile Workstation. Inject contrast thro...Attain Left Heart Delivery System
Description:Attain Left-heart Lead Delivery Systems. Medtronic offers left-heart lead delivery systems to assist with accessing the coronary sinus (cs)....Attain Prevail™ Steerable Catheter Left-Heart Lead Delivery System
Description:Steerability - Use the Attain Prevail's steerable tip, along with various fixed-shape guide catheters and guide wires, to obtain the curve you need, when you need it. Inject contrast media for improved visualization of the cardiac venous anatomy, adjust course as needed with tip deflection. Telescoping - Adjust curve and reach by telescoping the Attain Prevail through a straight or fixedshape gu...When Volume Matters, Immunoassay Systems Deliver
Although new and innovative technology has enabled more and more laboratory testing to occur at the bedside or physicians office, the central laboratory is hardly threatened with extinction. National volume data suggest that medium and large labs are busier than ever before, and the huge range of their capabilities, gold standard reliability and ability to handle very large volumes of tests a...