Opposing fat metabolism pathways triggered by a single gene
Regulating metabolism of fat is an important challenge for any animal, from nematodes to humans. Central players in the regulatory network are the nuclear hormone receptors (NHRs), which are transcription factors that turn on or off a set of target genes when bound by specific lipid molecules. In the premier open-access journal PLoS Biology, Keith Yamamoto and colleagues show that the nuclear hor...Not-for-profit publishers call NIH public access rule a missed opportunity
The final National Institutes of Health (NIH) rule on Enhanced Public Access to NIH Research Information is wasteful of federal research dollars and a missed opportunity to take advantage of...Comprehensive biodefense text published
A new book, Biological Weapons Defense: Infectious Disease and Counterbioterrorism, deals with the intentional causality of disease. Published by Humana Press, this text is also available in e-Book. Many of the contributors come from the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID), the nation's premier biodefense laboratory. In this 624-page, hardcover text edite...Enlisting genomics to understand flu evolution
Multiple strains of the flu virus, circulating in a population at the same time, can reshuffle their genes and create a new virus, one capable of infecting many more people, according to a new study in the open-access journal PLoS Biology. This finding may help scientists make better predictions about which viral strains will attack during upcoming flu seasons and design more effective flu vaccin...First production of human monoclonal antibodies in chicken eggs published in Nature Biotechnology
Chicken-produced antibodies demonstrate enhanced cell killing compared to conventionally produced anti-cancer antibodies Origen Therapeutics today announced the first published scientific report of fully functional, human sequence monoclonal antibodies (mAbs) produced in chickens. The antibodies were expressed solely in the chicken oviduct and deposited into egg white in concentrations of...Free Activin A ELISA Kit from Diagnostic Systems Laboratories, Inc.
Description:Activins are polypeptide hormones which belong to the transforming growth factor- (TGF-) superfamily. The TGF- superfamily is a large group of extra-cellular growth factors which control many aspects of development, reproductive function and tumor formation (1). Other members incude TGF-s, bone morphogenetic proteins, growth differentiation factors, AMH/MIS (Anti-Mullerian Hormone/Mullerian Inhib...Free Activin AB ELISA Kit from Diagnostic Systems Laboratories, Inc.
Description:Activins are polypeptide hormones which belong to the transforming growth factor- (TGF-) superfamily. The TGF- superfamily is a large group of extra-cellular growth factors which control many aspects of development, reproductive function and tumor formation (1). Other members incude TGF-s, bone morphogenetic proteins, growth differentiation factors, AMH/MIS (Anti-Mullerian Hormone/Mullerian Inhib...Free Activin B ELISA Kit from Diagnostic Systems Laboratories, Inc.
Description:Activins are polypeptide hormones which belong to the transforming growth factor- (TGF-) superfamily. The TGF- superfamily is a large group of extra-cellular growth factors which control many aspects of development, reproductive function and tumor formation (1). Other members incude TGF-s, bone morphogenetic proteins, growth differentiation factors, AMH/MIS (Anti-Mullerian Hormone/Mullerian Inhib...HIV-1 p24 ELISA Kit, Alliance (480 Tests) from PerkinElmer
Description:The PerkinElmer kit provides reagents for immune complex disruption (ICD) of antigen/antibody complexes in serum and plasma samples using a combination of low pH and heat. The samples are then neutralized and transferred to microplate wells which are coated with a highly specific mouse monoclonal antibody to HIV-1 p24. The immobilized monoclonal antibody captures both free HIV-1 p24 and that whic...Porcine Leptin ELISA Kit from Diagnostic Systems Laboratories, Inc.
Description:Leptin is a proteohormone with a molecular weight of 16 kDa. Leptin is a protein encoded by the ob gene and produced by adipocytes [1,2]. Leptin is thought to play a key role in the regulation of body weight [1-3]. In the human, leptin levels are elevated with increasing adiposity in both men and women [4]. A relationship between serum leptin levels and several measures of adiposity (e.g. bod...Two-dimensional Optimization of a Semi-nested PCR for Detecting Listeria monocytogenes
for Detecting Listeria monocytogenes Andrea Tanzer, Institute of Milk Hygiene, Milk Technology and Food Science, Austria Christian Rohrer, Eppendorf AG, Germany Introductio...Apollo Hospitals to consider listing on US Bourses in 2003
Health care major Apollo Hospitals announced on Thursday that plans are afoot to consider listing on US bourses in 2003. "We would consider listing on the US bourses after 2002," Pratap C Reddy, chairman of the Apollo Hospitals group said, adding it was a part of the business plan for the post-2002 period. Though further details are not available at the moment, Dr. Reddy added that plans...Long travel increase pulmonary embolism
According to researchers from France, the number of miles you fly affects your risk of pulmonary embolism. There's increasing concern that long haul travel could increase the risk of blood clotting in the veins of the legs (deep vein thrombosis, or DVT). If the clot breaks off, it may travel to the lungs, forming a pulmonary embolism (PE) which is a potentially life-threatening condition....Ranbaxy gets US FDA approval for Lisinopril
Ranbaxy Pharmaceuticals Inc (RPI) has received a tentative approval from the US FDA for Lisinopril tablets. Lisinopril is recommended for hypertension, either alone for initial therapy or with other classes of anti-hypertenive agents. It is also used as adjunctive therapy in the management of heart failure and patients who do not respond to diuretics. // However it expects to launch...Teens listen to parents about smoking
Contrary to the notion of the rebellious teenager who spurns parental guidance in favor of peer influence, new study findings suggest that adolescents who think their parents disapprove of smoking are less likely to pick up the habit. Teens are much less likely to smoke if they think their parents disapprove of the habit. Parental disapproval works even if the parents are smokers. Pa...Alcoholism Drug Fails To Prevent Drinking Relapses
The Food and Drug Administration approved naltrexone for the treatment of alcoholism in 1994. At that time, the only other drug therapy available was disulfiram, or Antabuse, which provokes a sickening reaction to alcohol.// A new study casts sobering doubts on earlier claims that an alcoholism drug can truly treat the addiction. The government is sponsoring a large trial comparing na...Holladay Posterior Capsule Polisher and Curette
Description:0.5 mm curette cup, reverse side of sandblasted to polish capsule. Round knurled handle with polished finish. Overall length: 5 inches....Gills-Welsh Curette Capsule Polisher
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Description:Silicone Capsule Polisher, 27 g. Silicon tip to provide squeegee effect. Overall length 22 mm. 5/box....Cobalis Reports Phase III Trial Results for PreHistin in Seasonal Allergic Rhinitis
IRVINE, Calif.--(BUSINESS WIRE)--Jul 6, 2007 - Cobalis Corp.(OTCBB:CLSC), a pharmaceutical development company specializing inanti-allergy medications, today reported preliminary top-lineresults from two Phase III clinical trials for its drugPreHistin(TM) in patients with moderate to moderately severeseasonal allergic rhinitis, commonly known as hay fever. The trialsshowed very low symptom...