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Lipofuscin in Medical News

Video: New Online Film Introduces Longevinex Advantage(TM) -- The First Resveratrol-Based Dietary Supplement to Address Both Cellular and Connective Tissue Aging

...g of telomeres (end caps on chromosomes), loss of cellular energy produced in the mitochondria, and progressive accumulation of cellular debris called lipofuscin which generates free radicals. The film explains, as exciting as the prospect of slowing the rate of aging is, so-called anti-aging resveratrol s...

Photos: For the First Time Researchers Show Reversal of an Aging Marker in the Human Retina Correlated with Visual Improvement Using a Nutraceutical Matrix (Longevinex(R))

...ve or reversing effect. Furthermore, it becomes evident that by measuring lipofuscin deposits, that not only the biological age of the human eye can be assessed...elp determine the biological age and the "speed of aging" of an individual. lipofuscin accumulates in all tissues of the body with advancing age. System-wide age-...

Blindness can be stopped with drug for acne treatment

... now found that Accutane, an acne treatment drug, stops the accumulation of lipofuscin in the eyes of mice with Stargardt's macular degeneration. Upon examination...el with humans with Stargardt's makes it likely that Accutane will suppress lipofuscin from accumulating in Stargardt's patients. ...
Lipofuscin in Medical Dictionary

Lipofuscin

Lipofuscin is the name given to finely granular yellow-brown pigment granules composed of lipid-containing residues of lysosomal digestion. It is considered one of the aging or "wear and tear" pigments, found in the liver, kidney, heart muscle, adrenals, nerve cells,... lipof...
Lipofuscin in Biological News

Iron-moving malfunction may underlie neurodegenerative diseases, aging

...scin, known as the "aging pigment." In skin cells, lipofuscin is the culprit responsible for the dreaded liver s...ccumulation has more serious consequences. "How lipofuscin causes problems in neurons and muscles is not clea...going to suffer." Indeed, abnormal accumulation of lipofuscin is associated with a range of disorders including ...
Lipofuscin in Biological Technology

Video: 8-Minute Film Documentary Explores Why Humans Age

... first-of-its-kind experiment where measurement of lipofuscin was performed by direct photography of the retina ...ggests a day when retinal photographs will measure lipofuscin levels to determine the biological age of an indiv...loyed to turn back biological time. The removal of lipofuscin would remove any theoretical limits on the maximum...

Sirion Therapeutics Preclinical Studies: Two New Potential Advances in Treatment of Retinal Diseases to be Presented at ARVO

...ll molecule non-retinoid modulators (NRMs) for reducing the accumulation of lipofuscin and A2E in the eye. Excessive accumulation of lipofuscin and a toxic vitamin A-based fluorophore (A2E) has been implicated in the de...
Lipofuscin in Biological Products

Autofluorescence Eliminator Reagent from CHEMICON

Description:... With increasing age, the autofluorescent pigment lipofuscin accumulates in the cytoplasm of many cell types, including neurons. The presence of lipofuscin granules can complicate the use of fluorescence microscopy in the central n...
Company:CHEMICON
Lipofuscin in Biological Definition

Neuron

...fibrils . Some neurons also contain pigment granules, such as neuromelanin (a brownish-black pigment, byproduct of synthesis of catecholamines) and lipofuscin (yellowish-brown pigment that accumulates with age). Neurons of the brain The nematode worm ( Caenorhabditis elegans ) has 302 neurons. Sc...
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